JP5483883B2 - 多環式アミノ酸誘導体及びその使用方法 - Google Patents

多環式アミノ酸誘導体及びその使用方法 Download PDF

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JP5483883B2
JP5483883B2 JP2008548561A JP2008548561A JP5483883B2 JP 5483883 B2 JP5483883 B2 JP 5483883B2 JP 2008548561 A JP2008548561 A JP 2008548561A JP 2008548561 A JP2008548561 A JP 2008548561A JP 5483883 B2 JP5483883 B2 JP 5483883B2
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amino
phenyl
propionic acid
pyrimidin
alkyl
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JP2009522265A (ja
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アロキアサミー デヴァサガヤラジ
ハイホン ジン
チンワン リウ
ブレット マリネリ
ラクシャマ サマラ
ジーカイ シー
アショック トゥヌーリ
イン ワン
ウェンシュエ ウー
チェンミン チャン
ハイミン チャン
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レクシコン ファーマシューティカルズ インコーポレイテッド
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    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
    • C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
    • C07D251/18—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom with nitrogen atoms directly attached to the two other ring carbon atoms, e.g. guanamines
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
JP2008548561A 2005-12-29 2006-12-12 多環式アミノ酸誘導体及びその使用方法 Active JP5483883B2 (ja)

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US75495505P 2005-12-29 2005-12-29
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PCT/US2006/047579 WO2007089335A2 (en) 2005-12-29 2006-12-12 Multicyclic amino acid derivatives and methods of their use

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JP5483883B2 true JP5483883B2 (ja) 2014-05-07

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EP2386547A1 (en) 2011-11-16
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