JP5340265B2 - 効率的な人工多能性幹細胞の樹立方法 - Google Patents
効率的な人工多能性幹細胞の樹立方法 Download PDFInfo
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- JP5340265B2 JP5340265B2 JP2010506749A JP2010506749A JP5340265B2 JP 5340265 B2 JP5340265 B2 JP 5340265B2 JP 2010506749 A JP2010506749 A JP 2010506749A JP 2010506749 A JP2010506749 A JP 2010506749A JP 5340265 B2 JP5340265 B2 JP 5340265B2
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/602—Sox-2
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
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- C12N2510/00—Genetically modified cells
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- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
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- Cell Biology (AREA)
- Transplantation (AREA)
- Developmental Biology & Embryology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7648708P | 2008-06-27 | 2008-06-27 | |
| US61/076,487 | 2008-06-27 | ||
| US9557308P | 2008-09-09 | 2008-09-09 | |
| US61/095,573 | 2008-09-09 | ||
| US19470008P | 2008-09-30 | 2008-09-30 | |
| US61/194,700 | 2008-09-30 | ||
| US20030708P | 2008-11-25 | 2008-11-25 | |
| US61/200,307 | 2008-11-25 | ||
| US20968609P | 2009-03-10 | 2009-03-10 | |
| US61/209,686 | 2009-03-10 | ||
| PCT/JP2009/062173 WO2009157593A1 (en) | 2008-06-27 | 2009-06-26 | Method of efficiently establishing induced pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011525793A JP2011525793A (ja) | 2011-09-29 |
| JP2011525793A5 JP2011525793A5 (https=) | 2012-08-16 |
| JP5340265B2 true JP5340265B2 (ja) | 2013-11-13 |
Family
ID=41444650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010506749A Active JP5340265B2 (ja) | 2008-06-27 | 2009-06-26 | 効率的な人工多能性幹細胞の樹立方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8530238B2 (https=) |
| EP (1) | EP2288692B1 (https=) |
| JP (1) | JP5340265B2 (https=) |
| KR (1) | KR101606943B1 (https=) |
| CN (1) | CN101835890B (https=) |
| CA (1) | CA2695590C (https=) |
| SG (1) | SG10201402428WA (https=) |
| WO (1) | WO2009157593A1 (https=) |
Families Citing this family (119)
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| CA2695590C (en) * | 2008-06-27 | 2018-01-09 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| WO2010013845A1 (en) * | 2008-07-30 | 2010-02-04 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| US9045737B2 (en) | 2008-12-13 | 2015-06-02 | Dnamicroarray, Inc. | Artificial three-dimensional microenvironment niche culture |
| US8470308B2 (en) * | 2009-01-03 | 2013-06-25 | Ray C. Wasielewski | Enhanced medical implant comprising disrupted tooth pulp and tooth particles |
| US10328103B2 (en) | 2009-01-03 | 2019-06-25 | Ray C. Wasielewski | Medical treatment composition comprising mammalian dental pulp stem cells |
| JP5637354B2 (ja) * | 2009-03-30 | 2014-12-10 | 独立行政法人産業技術総合研究所 | 精製転写因子の調製法と細胞導入技術 |
| DK2438160T3 (en) | 2009-06-05 | 2016-01-11 | Cellular Dynamics Int Inc | Reprogramming of T cells and hematopoietic cells |
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| KR20120061053A (ko) | 2009-08-27 | 2012-06-12 | 시냅틱 리서치, 엘엘씨 | 유도 만능 줄기(iPS) 세포 또는 조직 특이적 세포를 생성하기 위한 신규한 단백질 전달 시스템 |
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| US9206394B2 (en) | 2010-02-03 | 2015-12-08 | The University Of Tokyo | Method for reconstructing immune function using pluripotent stem cells |
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| AU2011241514A1 (en) * | 2010-04-16 | 2012-12-06 | Dnavec Corporation | Method for producing induced pluripotent stem cells |
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| JP5888753B2 (ja) | 2010-11-04 | 2016-03-22 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| JP6029137B2 (ja) * | 2010-12-03 | 2016-11-24 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| US9404082B2 (en) | 2010-12-03 | 2016-08-02 | Kyoto University | Method for production of eosinophil from pluripotent stem cell |
| CN102559587A (zh) * | 2010-12-16 | 2012-07-11 | 中国科学院上海药物研究所 | 诱导性多能干细胞的制备方法以及用于制备诱导性多能干细胞的培养基 |
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| PT2705143T (pt) | 2011-05-02 | 2021-04-07 | Univ Wayne State | Tecnologia de células pluripotentes induzidas por proteínas e utilizações da mesma |
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| NZ513487A (en) * | 1999-01-29 | 2003-02-28 | Univ Illinois | The use of a P53 inhibitor for the treatment of cancer, hyperthermia, hypoxia, a burn, trauma to the central nervous system, a seizure, acute inflammation, tissue ageing, preservation of organs for transplant and preparation of a host for bone marrow transplant |
| EP1619242A4 (en) * | 2003-03-25 | 2006-09-06 | Japan Science & Tech Agency | CONTROL OF THE INDUCTION AND STRENGTH OF STEM CELL DIFFERENTIATION |
| WO2005019440A1 (en) * | 2003-08-20 | 2005-03-03 | Northern Sydney And Central Coast Area Health Service | Methods for enhancing embryo viability |
| CA2561690A1 (en) | 2004-03-30 | 2005-10-27 | Kyoto University | Process for producing multipotential stem cell originating in testoid cell |
| KR20080009263A (ko) * | 2005-02-23 | 2008-01-28 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 불멸화된 지지 세포 |
| WO2006111010A1 (en) * | 2005-04-18 | 2006-10-26 | Research In Motion Limited | Centralized memory management in wireless terminal devices |
| BRPI0619794B8 (pt) | 2005-12-13 | 2022-06-14 | Univ Kyoto | Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| EP1847595B1 (en) * | 2006-04-20 | 2010-01-06 | Northern Sydney and Central Coast Area Health Service | Methods of assessing embryo viability |
| DK3399025T3 (da) | 2007-03-23 | 2025-06-16 | Wisconsin Alumni Res Found | Omprogrammering af somatiske celler |
| CN101550406B (zh) | 2008-04-03 | 2016-02-10 | 北京大学 | 制备多潜能干细胞的方法,试剂盒及用途 |
| CA2695590C (en) | 2008-06-27 | 2018-01-09 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| KR101774206B1 (ko) | 2009-08-07 | 2017-09-04 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
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| CN101835890A (zh) | 2010-09-15 |
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| EP2288692A1 (en) | 2011-03-02 |
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