JP5331680B2 - ｃ−ｆｍｓキナーゼの阻害剤 - Google Patents

ｃ−ｆｍｓキナーゼの阻害剤 Download PDF

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Publication number
JP5331680B2
JP5331680B2 JP2009506742A JP2009506742A JP5331680B2 JP 5331680 B2 JP5331680 B2 JP 5331680B2 JP 2009506742 A JP2009506742 A JP 2009506742A JP 2009506742 A JP2009506742 A JP 2009506742A JP 5331680 B2 JP5331680 B2 JP 5331680B2
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alkyl
compound
formula
pharmaceutically acceptable
cancer
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JP2009534406A5 (enExample
JP2009534406A (ja
Inventor
イリグ，カール・アール
チエン，ジンシエング
デスジヤーレイス，レネー・ルイーズ
ウイルソン，ケネス
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Janssen Pharmaceutica NV
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
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  • Hematology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
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  • Communicable Diseases (AREA)
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JP2009506742A 2006-04-20 2007-04-18 ｃ−ｆｍｓキナーゼの阻害剤 Expired - Fee Related JP5331680B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79366706P 2006-04-20 2006-04-20
US60/793,667 2006-04-20
PCT/US2007/066870 WO2007124321A1 (en) 2006-04-20 2007-04-18 Inhibitors of c-fms kinase

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Publication Number Publication Date
JP2009534406A JP2009534406A (ja) 2009-09-24
JP2009534406A5 JP2009534406A5 (enExample) 2010-05-13
JP5331680B2 true JP5331680B2 (ja) 2013-10-30

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JP2009506742A Expired - Fee Related JP5331680B2 (ja) 2006-04-20 2007-04-18 ｃ−ｆｍｓキナーゼの阻害剤
JP2009506744A Expired - Fee Related JP5331681B2 (ja) 2006-04-20 2007-04-18 ｃ−ｆｍｓキナーゼの阻害剤
JP2009506741A Expired - Fee Related JP5331679B2 (ja) 2006-04-20 2007-04-18 ｃ−ｆｍｓキナーゼの阻害剤

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JP2009506741A Expired - Fee Related JP5331679B2 (ja) 2006-04-20 2007-04-18 ｃ−ｆｍｓキナーゼの阻害剤

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US (7) US8815867B2 (enExample)
EP (3) EP2016070B1 (enExample)
JP (3) JP5331680B2 (enExample)
KR (3) KR101367646B1 (enExample)
CN (1) CN101472914B (enExample)
AR (3) AR060612A1 (enExample)
AU (3) AU2007240443B2 (enExample)
BR (1) BRPI0710548B8 (enExample)
CA (3) CA2649924C (enExample)
ES (3) ES2565238T3 (enExample)
IL (1) IL194845A (enExample)
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NZ (3) NZ572070A (enExample)
PE (1) PE20080074A1 (enExample)
RU (1) RU2475483C2 (enExample)
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TW (3) TWI411612B (enExample)
UA (1) UA93085C2 (enExample)
UY (1) UY30297A1 (enExample)
WO (3) WO2007124319A1 (enExample)
ZA (1) ZA200809873B (enExample)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
US20060281788A1 (en) * 2005-06-10 2006-12-14 Baumann Christian A Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor
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RU2008145763A (ru) 2010-05-27
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JP5331679B2 (ja) 2013-10-30
AR060612A1 (es) 2008-07-02
RU2475483C2 (ru) 2013-02-20
PE20080074A1 (es) 2008-02-11
US9403804B2 (en) 2016-08-02
CN101472914B (zh) 2015-05-20
WO2007124319A1 (en) 2007-11-01
KR20090015066A (ko) 2009-02-11
EP2016058B1 (en) 2016-01-06
EP2016074A1 (en) 2009-01-21
AU2007240443B2 (en) 2012-11-01
BRPI0710548B8 (pt) 2021-05-25
CA2649739A1 (en) 2007-11-01
CA2649924C (en) 2014-08-19
ES2565238T3 (es) 2016-04-01
TWI411612B (zh) 2013-10-11
US20140200245A1 (en) 2014-07-17
JP2009534405A (ja) 2009-09-24
US8722718B2 (en) 2014-05-13
KR101406877B1 (ko) 2014-06-13
EP2016070A1 (en) 2009-01-21
TW200806659A (en) 2008-02-01
MX2008013531A (es) 2009-01-20
TW200815414A (en) 2008-04-01
IL194845A0 (en) 2009-08-03
US9394289B2 (en) 2016-07-19
US20140378457A1 (en) 2014-12-25
EP2016074B1 (en) 2016-01-13
JP2009534407A (ja) 2009-09-24
UA93085C2 (en) 2011-01-10
NO20084896L (no) 2009-01-12
US9266866B2 (en) 2016-02-23
US20140329815A1 (en) 2014-11-06
EP2016058A1 (en) 2009-01-21
JP2009534406A (ja) 2009-09-24
AU2007240440B2 (en) 2012-09-20
IL194845A (en) 2014-11-30
AR060610A1 (es) 2008-07-02
HK1133878A1 (en) 2010-04-09
US20070249680A1 (en) 2007-10-25

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