JP5015896B2 - 流体を加圧するための装置 - Google Patents
流体を加圧するための装置 Download PDFInfo
- Publication number
- JP5015896B2 JP5015896B2 JP2008275711A JP2008275711A JP5015896B2 JP 5015896 B2 JP5015896 B2 JP 5015896B2 JP 2008275711 A JP2008275711 A JP 2008275711A JP 2008275711 A JP2008275711 A JP 2008275711A JP 5015896 B2 JP5015896 B2 JP 5015896B2
- Authority
- JP
- Japan
- Prior art keywords
- hollow piston
- valve member
- fluid
- piston
- cylinder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1001—Piston pumps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1066—Pump inlet valves
- B05B11/1067—Pump inlet valves actuated by pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/108—Means for counting the number of dispensing strokes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
- B05B11/1091—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring being first hold in a loaded state by locking means or the like, then released
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
- F04B53/10—Valves; Arrangement of valves
- F04B53/12—Valves; Arrangement of valves arranged in or on pistons
- F04B53/125—Reciprocating valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7545—General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
- B05B11/026—Membranes separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
- Y10T137/7837—Direct response valves [i.e., check valve type]
- Y10T137/7904—Reciprocating valves
- Y10T137/7908—Weight biased
- Y10T137/7909—Valve body is the weight
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
- Y10T137/7837—Direct response valves [i.e., check valve type]
- Y10T137/7904—Reciprocating valves
- Y10T137/7908—Weight biased
- Y10T137/7909—Valve body is the weight
- Y10T137/7913—Guided head
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
- Y10T137/7837—Direct response valves [i.e., check valve type]
- Y10T137/7904—Reciprocating valves
- Y10T137/7908—Weight biased
- Y10T137/7909—Valve body is the weight
- Y10T137/7913—Guided head
- Y10T137/7915—Guide stem
- Y10T137/7916—With closing stop
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Details Of Reciprocating Pumps (AREA)
- Reciprocating Pumps (AREA)
- Nozzles (AREA)
- Catching Or Destruction (AREA)
- Pens And Brushes (AREA)
- Fluid-Pressure Circuits (AREA)
- Spray Control Apparatus (AREA)
Description
弁部材は中空ピストンに対していくぶん変位できるが、実質的には中空ピストンと一緒に動く。
弁部材はそれが可動状態で取付けられた室で案内され、円筒形の弁部材が必要に応じてその軸線まわりに回転することができるが、その軸線は中空ピストンの軸線に対して常に平行にとどまる。これは、密封面を弁部材の入口端部に作り出す。
弁部材が中空ピストンに対して移動できる距離は、可動弁部材を中空ピストンと一緒に保持する止めあるいは止め手段によって制限される。
弁部材が中空ピストンの止めと当接する位置で、弁は開く。弁部材が、密封面と当接する位置で、弁は閉じる。
中空ピストンの内側に配置された弁部材は、実質的に、中空ピストンの内壁面との摩擦がない。中空ピストンの端部の前に直接配置された弁部材は、装置の主ポンプ・シリンダの壁面とこすれ合う可能性がある。この場合、弁部材とシリンダ壁面との摩擦のため、中空ピストンが動くにつれて弁は積極的に開閉される。
流体が吸い込まれるとき、高圧室は中空ピストンによって流体の供給源に連結される。中空ピストンの吸入ストロークの間、流体は中空ピストンを通して、そして、弁部材を過ぎてシリンダの高圧室に流れる。中空ピストンの排出ストロークの間、弁座は、高圧の緊密な方法で弁部材の密封面に対して密閉される。
広くなった入口端部を持つ中空ピストンは、好ましくは、金属で構成される。
以下、アトマイザのさらに好ましい特徴を説明する。このアトマイザは、好ましくは、計量式投与吸入器である。
ノズル部材におけるノズルは、好ましくは、ミクロ構造で作られる。すなわち、マイクロ技術によって製造される。ミクロ構造に作られたノズル部材は、たとえば、米国特許第5472143号(これの全内容をここに援用する)に開示されている。
このリングは、アトマイザの軸線に対して直角に配置される。ばねのバイアス作用後、阻止部材の阻止面は、従動フランジの経路内へ動き、ばねが解放されるのを防ぐ。阻止部材はボタンによって作動させられる。作動ボタンは阻止部材に連結される。阻止機構を作動させるためには、作動ボタンをリングの平面に対して平行に、好ましくはアトマイザ内へ押し込む。それによって、変形可能なリングはリングの平面内で変形し、フランジを解放してばねによって動けるようにする。
下方ハウジング部分は、ばねハウジング上を軸線方向に押され、取り付け部、スピンドルの駆動装置および流体のための貯蔵容器を覆う。スライダの位置は下方ハウジング部分の凹部を通して見ることができ、たとえば下方ハウジング部分にあるスケール上で読み取ることができる。
スライダの位置は、霧化すべき流体のどのくらいの割合が貯蔵容器から既に吸い出されているか、ならびに、どのくらいをまだ利用できるかを示す。スピンドル上のスライダは、必要に応じて、リセット用突起によってリセットすることができる。
寸法的に安定した外側の部分と液体を取り出したときに折り畳むことができる内側部分とを備えた適当な容器が米国特許第5316135号に開示されている。この米国特許の全内容をここに援用する。
アトマイザの構成要素は、この作用にふさわしい材料で作る。アトマイザのハウジング、そして、機能的に許す限り、他の部分はプラスチックで、たとえば射出成形によって作ると好ましい。医薬の目的のために、生理学的に許容可能な材料が使われる。
溶液は薬学的に受け入れ可能な補形薬を含んでいてもよい。
− この装置は、いかなる補助力(ばねによって生成される)もなしに作動し、弁部材に加わる流体の流れ抵抗あるいはシリンダ壁面に対する摩擦の結果として閉まる弁を包含する。
− 弁が、一般に3MPa(30バール)よりかなり上の圧力に対して緊密である。
− 弁部材は一体片として作られ、製造、組み立てが簡単である。
− 弁は、弁部材が密封面に到着するために移動する距離が短いために、かなり急速に閉じる。
− 弁は高い密閉作用を有する。
− 短軸方向に回転対称である弁部材を案内する結果として、密封面が作り出され、これは非常に多い回数の中空ピストンの移動サイクルを通じて高圧に対して気密である。
− アトマイザは、ばねを片寄せ、霧化プロセスを開始させるのに技術的に未熟な人によっても安全かつ容易に操作することができる。
− アトマイザはスプレー用のガスなしで作動し、したがって、環境に優しい。
− 流体貯蔵容器を、加圧しないか、実質的に加圧しない。
− 阻止部材の動きが、単純な方法によって、ばねに片寄せる回転運動に自動的に連結される。
− 好ましい実施の形態において、アトマイザは低摩耗性の純粋に機械的な構成要素からなり、長期間にわたって信頼性をもって動作する。
− 従動部分のための定まった当接により、流体の計量は非常に正確である。
− アトマイザを、安価に製作し、簡単に組み立てることができる。
− アトマイザが正しく使われているとき、カウンタにはアクセスできず、偶発的に故障することがあり得ない。
− カウンタは貯蔵容器から流体を何回も放出させることができ、1つのアトマイザで異なった数の貯蔵容器を使用できる。
− カウンタはアトマイザに組み込まれ、なんら追加のスペースも必要としない。
− 物質がカウンタから霧化すべき物質に通過することができない。
ポンプ装置のいろいろな実施の形態を既に一般的な用語で説明してきたが、これらの説明を、以下、図面を参照した更なる説明で補うことにする。
図1aは、流体に高圧を発生させるための本発明による装置の第1の実施の形態の縦断面斜視図を示す。同軸のボア(7)を持つ中空ピストン(2)と、弁の部分的に開いた位置における弁部材(3)が、シリンダ(1)内にある。高圧室(4)が、弁部材(3)の底とシリンダ端部との間にある。高圧室は、別の構成要素(図示せず)によって閉じられている。中空ピストンをシリンダ内で変位させることができる装置(図示せず)が、中空ピストン上でシリンダの外側に取付けられている。
組み立て中、弁部材(3)は中空ピストン(2)の端部上に置かれ、フック(10)が溝の中に摺動する。次に、弁部材と一緒に中空ピストンをシリンダ内に押し込む。
流体を取り入れるために、中空ピストンはシリンダから部分的に持ち上げられる。このとき、弁は自動的に開く。流体は、中空ピストンのボア(7)を通って、そして、弁部材を過ぎて高圧室(4)内に流れる。流体を追い出すために、中空ピストン(2)をシリンダ(1)に押し込み、このとき弁がほぼ瞬時に自動的に閉まり、高圧が流体に生じる。
図2bは、中空ピストン(11)の形成出口端部(12)をもった中空ピストン(11)の縦断面図を示す。変位体(26)を中空ピストン内に固定して設置するのがよい。
図3bは、形成端部(19)を持つ中空ピストン(17)の斜めに見た縦断面図を示す。中空ピストンの出口端部のところには広くなった部分(20)があり、ここにおいて、弁部材(18)は軸線方向に移動できる方法で案内され、取付けられている。広くなった部分(20)の入口端部は面取りしてあってもよいし、あるいは、平らであってもよい。
図4bは、内曲がりのリップを形成する形成出口端部(24)を持つ中空ピストン(22)および周方向のくびれ(25)の縦断面斜視図を示す。変位体として作用する厚肉管(26)を中空ピストン(22)内に押し込み、そこに固着してもよい。
図4dは、本発明に関連する装置の第2の例の変形例を縦断面斜視図で示す。選択的には、変位体(26)を有する中空ピストン(28)がシリンダ(1)内にあり、弁は閉じた位置にある。弁部材(29)の直径は中空ピストンの内径撚りも小さい。
図4fは、弁部材(29)を斜視図で示す。この場合、弁部材は凹部のない真っ直ぐなシリンダである。
図面に示した実施の形態はさらに変更可能である。構成要素は図面に示す方法以外の方法で一緒に使用してもよい。
図1aに示す医薬アトマイザの弁領域は、1.6mmの内径と5mmの外径を持つポリブチレン−テレフタレートで作ったシリンダからなる。高圧室は、ノズル・キャリヤ・プレートで閉じてある。このプレートにおいて、ノズル直径は20μmであり、ノズル・チャネルは長さ2mmである。
図3aに対応する化粧用アトマイザの弁領域は、2.5mm内径と8mm外径を持つポリエーテルエーテル−ケトン(polyetherether-ketone)のシリンダからなる。高圧室は、ノズル・キャリヤ・プレートで閉じられている。このプレートには、2mm長のノズル・チャネルを持つ直径25μmのノズルがある。
2.48mm外径を持ち、0.5mm直径のボアを有する強化プラスチックの中空ピストンをシリンダに押し込む。中空ピストンはシリンダ内へ45mm押し込むことができ、そのストロークは24mmである。中空ピストンは、その出口端部で5.0mmの長さにわたって1.85mmの内径まで穿孔してある。中空ピストンにおける穿孔形成した室のベースは面取りしてある。中空ピストンの出口端部は熱的に変形させる。
投与体積は約116mm3である。流体の圧力は約3MPa(30バール)である。
このアトマイザはヘアスプレーを霧化するのに使用される。
2 中空ピストン
3 弁部材
4 高圧室
5 溝
6 スナップ・フック
7 ボア
8 段部
9 チャネル
10 フック
11 中空ピストン
13 弁部材
12 縁
14 アンダカット・ペグ
15 ペグの端部
16 ボア
Claims (2)
- 流体を加圧するための小型化された構造の装置であって、
該装置は、シリンダ(1)内で移動できるピストン(2、11、17、22、28、33)と、前記シリンダ内でピストンの前方に位置した高圧室(4)と、弁部材(3、13、18、23、29、37)とを備え、
前記ピストン(2)は円筒形の中空ピストンであり、
前記弁部材(3)は、円筒形の弁部材であり、前記弁部材の外周面を延びる一又は二以上のチャネルを有し、
前記円筒形の弁部材は、いかなる補助的な力もなしに開放位置と閉鎖位置との間を移動可能であり、
前記円筒形の弁部材は、前記中空ピストンによって案内され、前記中空ピストンに抗して軸線方向に移動でき、
前記円筒形の弁部材の軸線方向の移動を制限する止め手段が、前記中空ピストンに設けられ、
密封面が、前記弁部材の入口端部に設けられている、
ことを特徴とする装置。 - 前記中空ピストン(2)の出口端部のところの前記止め手段は、周方向の溝、又は、周方向の外向きのロート形の縁を有して形成されたテーパとして形成され、前記中空ピストンの出口端部のところでの外径は、前記溝のベース直径、又は、前記テーパの外径より大きく、かつ、前記シリンダの直径よりも小さく、或いは、
平らな表面をもつ前記中空ピストンの出口端部に設けられた直径方向内方に延びるいくつかの部分と、段部とが前記止め手段として作用する、
請求項1に記載の装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19536902.5 | 1995-10-04 | ||
DE19536902A DE19536902A1 (de) | 1995-10-04 | 1995-10-04 | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007006590A Division JP2007092762A (ja) | 1995-10-04 | 2007-01-16 | アトマイザ |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2009019637A JP2009019637A (ja) | 2009-01-29 |
JP2009019637A6 JP2009019637A6 (ja) | 2009-04-02 |
JP5015896B2 true JP5015896B2 (ja) | 2012-08-29 |
Family
ID=7773961
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002150712A Withdrawn JP2003056458A (ja) | 1995-10-04 | 2002-05-24 | 流体を加圧するための小型化された構造の装置 |
JP2007006590A Pending JP2007092762A (ja) | 1995-10-04 | 2007-01-16 | アトマイザ |
JP2008275711A Expired - Lifetime JP5015896B2 (ja) | 1995-10-04 | 2008-10-27 | 流体を加圧するための装置 |
JP2010053741A Pending JP2010138913A (ja) | 1995-10-04 | 2010-03-10 | アトマイザ |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002150712A Withdrawn JP2003056458A (ja) | 1995-10-04 | 2002-05-24 | 流体を加圧するための小型化された構造の装置 |
JP2007006590A Pending JP2007092762A (ja) | 1995-10-04 | 2007-01-16 | アトマイザ |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010053741A Pending JP2010138913A (ja) | 1995-10-04 | 2010-03-10 | アトマイザ |
Country Status (39)
Country | Link |
---|---|
US (7) | US5964416A (ja) |
EP (2) | EP0853501B1 (ja) |
JP (4) | JP2003056458A (ja) |
KR (1) | KR100431011B1 (ja) |
CN (1) | CN1091660C (ja) |
AR (1) | AR003794A1 (ja) |
AT (2) | ATE352379T1 (ja) |
AU (1) | AU730797B2 (ja) |
BG (1) | BG64081B1 (ja) |
BR (1) | BR9611140A (ja) |
CA (4) | CA2232151C (ja) |
CO (1) | CO4560418A1 (ja) |
CZ (1) | CZ295103B6 (ja) |
DE (3) | DE19536902A1 (ja) |
DK (2) | DK0853501T3 (ja) |
EE (1) | EE03519B1 (ja) |
EG (1) | EG21374A (ja) |
ES (2) | ES2280442T3 (ja) |
HK (1) | HK1015304A1 (ja) |
HR (1) | HRP960448B1 (ja) |
HU (1) | HU221232B1 (ja) |
IL (3) | IL123634A (ja) |
MY (1) | MY115214A (ja) |
NO (2) | NO981521L (ja) |
NZ (1) | NZ320179A (ja) |
PE (1) | PE29098A1 (ja) |
PL (2) | PL185631B1 (ja) |
PT (2) | PT1214985E (ja) |
RU (1) | RU2179075C2 (ja) |
SA (1) | SA97170624B1 (ja) |
SI (2) | SI1214985T1 (ja) |
SK (1) | SK283515B6 (ja) |
TR (1) | TR199800586T1 (ja) |
TW (1) | TW364041B (ja) |
UA (1) | UA54402C2 (ja) |
UY (1) | UY24339A1 (ja) |
WO (1) | WO1997012687A1 (ja) |
YU (1) | YU49228B (ja) |
ZA (1) | ZA968317B (ja) |
Families Citing this family (291)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
DE19536902A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
DE19545226C1 (de) * | 1995-12-05 | 1997-06-19 | Boehringer Ingelheim Int | Sperrspannwerk für einen federbetätigten Abtrieb |
DE19653969A1 (de) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
US20030215396A1 (en) * | 1999-09-15 | 2003-11-20 | Boehringer Ingelheim Pharma Kg | Method for the production of propellant gas-free aerosols from aqueous medicament preparations |
US20030203036A1 (en) | 2000-03-17 | 2003-10-30 | Gordon Marc S. | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients |
DE19708143A1 (de) * | 1997-02-28 | 1998-09-03 | Itt Mfg Enterprises Inc | Pumpenkolben mit Verstärkungseinsatz und/oder Kunststoffventilkörper |
DE19733651A1 (de) * | 1997-08-04 | 1999-02-18 | Boehringer Ingelheim Pharma | Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole |
US20060239930A1 (en) * | 1997-08-04 | 2006-10-26 | Herbert Lamche | Process for nebulizing aqueous compositions containing highly concentrated insulin |
DE19742439C1 (de) | 1997-09-26 | 1998-10-22 | Boehringer Ingelheim Int | Mikrostrukturiertes Filter |
US7963955B2 (en) * | 1998-02-27 | 2011-06-21 | Boehringer Ingelheim International Gmbh | Container for a medicinal liquid |
DE19808295A1 (de) | 1998-02-27 | 1999-11-11 | Boehringer Ingelheim Int | Behälter für eine medizinische Flüssigkeit |
DE19847968A1 (de) | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen |
DE19851404A1 (de) | 1998-11-07 | 2000-05-11 | Boehringer Ingelheim Int | Druckausgleichsvorrichtung für einen Doppelbehälter |
DE19940713A1 (de) | 1999-02-23 | 2001-03-01 | Boehringer Ingelheim Int | Kartusche für eine Flüssigkeit |
ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
US20020025827A1 (en) * | 2000-08-21 | 2002-02-28 | Song Chang June | Extendable antenna for wireless telephones |
DE10190607B4 (de) * | 2000-02-17 | 2007-12-06 | Lg Electronics Inc. | Ansauggasventilvorrichtung eines Kolbenverdichters |
US6689092B2 (en) * | 2000-03-03 | 2004-02-10 | Boehringer International Gmbh | Needle-less injector of miniature type |
DE10010123A1 (de) * | 2000-03-03 | 2001-09-20 | Boehringer Ingelheim Int | Nadelloser Injektor in Miniaturausführung |
US7575761B2 (en) | 2000-06-30 | 2009-08-18 | Novartis Pharma Ag | Spray drying process control of drying kinetics |
GB0016123D0 (en) * | 2000-07-01 | 2000-08-23 | Glaxo Group Ltd | Valve for aerosol container |
AU2001277230A1 (en) * | 2000-08-01 | 2002-02-13 | Inhale Therapeutic Systems, Inc. | Apparatus and process to produce particles having a narrow size distribution andparticles made thereby |
US20020137764A1 (en) * | 2000-10-31 | 2002-09-26 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
US20020111363A1 (en) * | 2000-10-31 | 2002-08-15 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
EP1837021A3 (de) * | 2000-10-31 | 2008-03-19 | Boehringer Ingelheim Pharma GmbH & Co. KG | Inhalative Lösungsformulierung mit einem Tiotropiumsalz |
FR2817247B1 (fr) * | 2000-11-24 | 2003-02-14 | Valois Sa | Dispositif de distribution de produit fluide |
EG24184A (en) | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
DE10131178A1 (de) * | 2001-06-29 | 2003-01-16 | Boehringer Ingelheim Pharma | Vernebler zur Applikation von Flüssigkeiten in die Augen |
DE10136555A1 (de) | 2001-07-27 | 2003-02-13 | Boehringer Ingelheim Int | Optimierte Verfahren zur Bestimmung der Aerosol-Partikelgrößenverteilung und Vorrichtung zur Durchführung derartiger Verfahren |
US6945472B2 (en) | 2001-09-04 | 2005-09-20 | Boehringer Ingelheim International Gmbh | Locking-stressing mechanism for a miniaturised high pressuriser |
DE10143350A1 (de) * | 2001-09-04 | 2003-03-20 | Boehringer Ingelheim Int | Sperrspannwerk für einen miniaturisierten Hochdruckerzeuger |
DE60227691D1 (de) | 2001-11-01 | 2008-08-28 | Nektar Therapeutics | Sprühtrocknungsverfahren |
DE10154237A1 (de) | 2001-11-07 | 2003-05-15 | Steag Microparts Gmbh | Zerstäuber für manuelle Betätigung |
SE0200312D0 (sv) * | 2002-02-01 | 2002-02-01 | Astrazeneca Ab | Novel composition |
US20030225089A1 (en) * | 2002-04-10 | 2003-12-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and p38 kinase inhibitors |
DE10216036A1 (de) | 2002-04-11 | 2003-10-23 | Boehringer Ingelheim Pharma | Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz |
DE10216429A1 (de) | 2002-04-12 | 2003-10-23 | Boehringer Ingelheim Pharma | Arzneimittel enthaltend Steroide und ein neues Anticholinergikum |
GB0216562D0 (en) | 2002-04-25 | 2002-08-28 | Bradford Particle Design Ltd | Particulate materials |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
DK1509266T3 (da) | 2002-05-16 | 2009-10-19 | Boehringer Ingelheim Int | System omfattende en dyse og et holdersystem |
DE10225470A1 (de) | 2002-06-08 | 2003-12-18 | Boehringer Ingelheim Int | Vernebler mit Merkhilfe für das Therapieregiment |
JP2005538066A (ja) | 2002-07-09 | 2005-12-15 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 新規な抗コリン作用薬及びp38キナーゼ阻害剤を用いた新規な医薬組成物 |
DE10230751A1 (de) | 2002-07-09 | 2004-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern |
US20040166065A1 (en) | 2002-08-14 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation comprising an anticholinergic |
US7396341B2 (en) | 2002-08-28 | 2008-07-08 | Boehringer Ingelheim International Gmbh | Blocking device for a locking stressing mechanism having a spring-actuated output drive device |
DE10239443A1 (de) * | 2002-08-28 | 2004-03-11 | Boehringer Ingelheim International Gmbh | Blockiervorrichtung für ein Sperrspannwerk mit federbetätigtem Abtrieb |
US7699052B2 (en) * | 2002-09-05 | 2010-04-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Apparatus for the dispensing of liquids, container cartridge suitable for this, and system comprising the apparatus for the dispensing of liquids, and the container cartridge |
CA2497680C (en) * | 2002-09-05 | 2010-12-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Apparatus for the dispensing of liquids, container cartridge suitable for this, and system comprising the apparatus for the dispensing of liquids and the container cartridge |
DE10243255A1 (de) | 2002-09-17 | 2004-03-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zum Messen der Dichtigkeit von Folienbehältnissen |
US7056916B2 (en) | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
BR0316603B1 (pt) * | 2002-12-13 | 2014-03-11 | Otsuka Pharma Co Ltd | Dispositivo de inalação para administração transpulmonar |
JP4808970B2 (ja) | 2002-12-30 | 2011-11-02 | ネクター セラピューティクス | 噴霧乾燥システム |
DE10300983A1 (de) | 2003-01-14 | 2004-07-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Düsensystem für eine Ausbringungsvorrichtung für Flüssigkeiten bestehend aus Düse und Düsenhalter und/oder Überwurfmutter |
US7621266B2 (en) * | 2003-01-14 | 2009-11-24 | Boehringer Ingelheim International Gmbh | Nozzle-system for a dispenser for fluids consisting of a nozzle and a nozzle-holder and/or screw cap |
GB0300939D0 (en) * | 2003-01-16 | 2003-02-12 | Unilever Plc | Method of creating a cosmetic spray |
PE20040950A1 (es) | 2003-02-14 | 2005-01-01 | Theravance Inc | DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS |
DE50306841D1 (de) * | 2003-02-21 | 2007-05-03 | Boehringer Ingelheim Micropart | Spender zum Abgeben eines flüssigen oder pastösen Mediums |
US7683029B2 (en) * | 2003-05-07 | 2010-03-23 | Philip Morris Usa Inc. | Liquid aerosol formulations containing insulin and aerosol generating devices and methods for generating aerosolized insulin |
CN100435970C (zh) * | 2003-07-16 | 2008-11-26 | 泊灵格英格尔海姆药品两合公司 | 一种用板状复合结构来生产微流体装置的工艺方法 |
PT1644129E (pt) * | 2003-07-16 | 2007-01-31 | Boehringer Ingelheim Pharma | Processo de produção de configurações microfluídicas a partir de uma estrutura compósita em forma de placa |
US20050017089A1 (en) * | 2003-07-21 | 2005-01-27 | Marc Rohrschneider | Finger operated spray pump |
PL1651270T3 (pl) | 2003-07-29 | 2007-06-29 | Boehringer Ingelheim Int | Leki do inhalacji zawierające betamimetyki i środki przeciwcholinergiczne |
US20050026948A1 (en) * | 2003-07-29 | 2005-02-03 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a betamimetic |
UY28526A1 (es) | 2003-09-24 | 2005-04-29 | Boehringer Ingelheim Pharma | Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos |
CN1875020B (zh) | 2003-11-03 | 2010-04-28 | 贝林格尔.英格海姆国际有限公司 | 新颖的噻托铵盐,其制备方法及其药物制剂 |
SG137859A1 (en) | 2003-11-03 | 2007-12-28 | Boehringer Ingelheim Int | Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same |
DE102004001451A1 (de) * | 2004-01-08 | 2005-08-11 | Boehringer Ingelheim International Gmbh | Vorrichtung zum Haltern eines fluidischen Bauteiles |
CN100337049C (zh) * | 2004-02-23 | 2007-09-12 | 沈阳东岳液压工程有限公司 | 一种用于大型设备防冲击振动的微分动压反馈装置 |
DE102004009434A1 (de) | 2004-02-24 | 2005-12-15 | Boehringer Ingelheim International Gmbh | Zerstäuber |
JP2007522902A (ja) | 2004-02-24 | 2007-08-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
DE102004009435A1 (de) | 2004-02-24 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Zerstäuber |
DE102004009436A1 (de) * | 2004-02-24 | 2005-10-13 | Boehringer Ingelheim International Gmbh | Zerstäuber |
US20050272726A1 (en) * | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
ATE539754T1 (de) | 2004-04-22 | 2012-01-15 | Boehringer Ingelheim Int | Arzneinmittelkombinationen enthaltend benzoxazine zur behandlung von atemwegserkrankungen |
DE102004021789A1 (de) * | 2004-05-03 | 2006-04-27 | Boehringer Ingelheim International Gmbh | Zerstäuber zum Ausbringen von Flüssigkeiten für medizinische Zwecke |
US7723306B2 (en) | 2004-05-10 | 2010-05-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation |
US7611709B2 (en) | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
US7727962B2 (en) | 2004-05-10 | 2010-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder comprising new compositions of oligosaccharides and methods for their preparation |
US20050255050A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
US7220742B2 (en) * | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
DE602005022499D1 (de) | 2004-05-31 | 2010-09-02 | Almirall Sa | Kombinationen mit Antimuskarin-Wirkstoffen und PDE4-Hemmern |
ES2257152B1 (es) | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
US20060035893A1 (en) | 2004-08-07 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders |
US20060081242A1 (en) * | 2004-09-15 | 2006-04-20 | Tai-Kang Han | Portable air pre-treating device for medical treatment |
US20070020330A1 (en) | 2004-11-24 | 2007-01-25 | Medpointe Healthcare Inc. | Compositions comprising azelastine and methods of use thereof |
US8758816B2 (en) | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
LT2486942T (lt) | 2004-11-24 | 2019-01-25 | Meda Pharmaceuticals Inc. | Kompozicijos, apimančios azelastiną ir jų panaudojimo būdai |
WO2006102783A1 (de) * | 2005-03-30 | 2006-10-05 | Sogno Ag | Kleberauftragsstation zum binden von druckerzeugnissen |
CN101184522B (zh) | 2005-05-18 | 2011-12-21 | 尼克塔治疗公司 | 用于支气管内治疗的阀、设备和方法 |
ES2265276B1 (es) | 2005-05-20 | 2008-02-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
DE102005024439A1 (de) | 2005-05-24 | 2006-12-07 | Boehringer Ingelheim International Gmbh | Zerstäuber |
WO2006134022A1 (en) * | 2005-06-17 | 2006-12-21 | Boehringer Ingelheim International Gmbh | Mrp iv inhibitors for the treatment of respiratory diseases |
FR2887232B1 (fr) * | 2005-06-21 | 2010-11-05 | Rexam Dispensing Sys | Embout poussoir pour distributeur de produit liquide |
DE102005063657B3 (de) | 2005-06-24 | 2022-11-03 | Boehringer Ingelheim International Gmbh | Zerstäuber und Behälter |
DE102005029746B4 (de) | 2005-06-24 | 2017-10-26 | Boehringer Ingelheim International Gmbh | Zerstäuber |
DE602006016280D1 (de) | 2005-06-29 | 2010-09-30 | Boehringer Ingelheim Int | Verfahren und vorrichtung zum zerstäuben einer flüssigkeit |
DE102005030733A1 (de) | 2005-07-01 | 2007-01-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff |
DE102005035715A1 (de) | 2005-07-27 | 2007-02-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Überprüfung der Permeabilitätsrate eines geschlossenen Behälters |
ES2530991T3 (es) | 2005-08-15 | 2015-03-09 | Boehringer Ingelheim Int | Procedimiento para la obtención de betamiméticos |
CN101247897B (zh) | 2005-08-24 | 2013-06-12 | 贝林格尔·英格海姆国际有限公司 | 雾化器 |
TWI396541B (zh) | 2005-10-10 | 2013-05-21 | Boehringer Ingelheim Int | 用於治療呼吸疾病之新穎藥物組合 |
DE102005052898A1 (de) * | 2005-11-03 | 2007-05-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren und Vorrichtung zum Dosieren von Arzneimitteln |
US7423146B2 (en) | 2005-11-09 | 2008-09-09 | Boehringer Ingelheim International Gmbh | Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones |
EP1792660A1 (en) | 2005-12-02 | 2007-06-06 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
ATE460993T1 (de) * | 2006-01-25 | 2010-04-15 | Technical Concepts Bentfield B | Flüssigkeitsspender und pumpe mit ständig offenem einlassventil |
DE102006022002A1 (de) * | 2006-05-10 | 2007-11-15 | Boehringer Ingelheim International Gmbh | Zerstäuber und Verfahren zur Zerstäubung von Fluid |
EP2026785A1 (de) | 2006-05-19 | 2009-02-25 | Boehringer Ingelheim International GmbH | Treibgasfreie aerosolformulierung für die inhalation enthaltend ipratropiumbromid und salbutamolsulfat |
US8061350B2 (en) * | 2006-06-02 | 2011-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process and device for dosing pharmaceutical agents |
EP2044352A4 (en) * | 2006-07-25 | 2013-01-23 | Waters Technologies Corp | NON-RETURN VALVE WITH FLEXIBLE SEAL |
EP2081905B1 (en) | 2006-07-28 | 2012-09-12 | Boehringer Ingelheim International GmbH | Sulfonyl compounds which modulate the cb2 receptor |
ATE505193T1 (de) | 2006-08-07 | 2011-04-15 | Boehringer Ingelheim Int | Arzneimittelkombinationen zur behandlung von atemwegserkrankungen |
PE20080610A1 (es) | 2006-08-22 | 2008-07-15 | Boehringer Ingelheim Int | Nuevos beta-agonistas enantiomericamente puros, procedimientos para su preparacion y uso como medicamentos |
JP5030114B2 (ja) | 2006-09-25 | 2012-09-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体をモジュレートする化合物 |
DE102006049185A1 (de) | 2006-10-18 | 2008-04-24 | Bayerl, Thomas M., Prof. Dr. | Verwendung von Deuteriumdioxid zur Behandlung von hyperproliferativen Erkrankungen der Haut |
ES2306595B1 (es) | 2007-02-09 | 2009-09-11 | Laboratorios Almirall S.A. | Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2. |
ES2320955B1 (es) | 2007-03-02 | 2010-03-16 | Laboratorios Almirall S.A. | Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida. |
DE102007020578A1 (de) * | 2007-05-02 | 2008-11-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Wässrige Aerosolzubereitungen enthaltend therapeutisch wirksame Mikroorganismen oder Teile von Mikroorganismen und Verfahren zur Erzeugung entsprechender Aerosole |
DE102007023012A1 (de) | 2007-05-15 | 2008-11-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Zerstäuber und Filter |
EP2155306A2 (en) | 2007-06-15 | 2010-02-24 | Boehringer Ingelheim International GmbH | Inhaler |
DE102007031397A1 (de) | 2007-07-05 | 2009-01-08 | D2O Bioscience Group Ltd. | Verwendung von Deuteriumoxid zur Behandlung von Virus-basierten Erkrankungen der Haut |
EP2044967A1 (de) * | 2007-10-01 | 2009-04-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Zerstäuber |
ES2320961B1 (es) | 2007-11-28 | 2010-03-17 | Laboratorios Almirall, S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2. |
JP5427185B2 (ja) | 2007-11-29 | 2014-02-26 | グラクソ グループ リミテッド | 分配デバイス |
EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
DE102008003542A1 (de) * | 2008-01-08 | 2009-07-09 | Franz Und Peter Brunner Gbr (Vertretungsberechtigte Gesellschafter: Franz Brunner | Vorrichtung zum Zerstäuben von wenigstens zwei unterschiedlichen Fluiden |
EP2093219A1 (de) | 2008-02-22 | 2009-08-26 | Boehringer Ingelheim International Gmbh | Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel |
EP2096105A1 (en) | 2008-02-28 | 2009-09-02 | Laboratorios Almirall, S.A. | Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor |
EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
EP2108641A1 (en) | 2008-04-11 | 2009-10-14 | Laboratorios Almirall, S.A. | New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors |
ES2459198T3 (es) | 2008-04-20 | 2014-05-08 | D2 Bioscience Group Ltd | Utilización de óxido de deuterio como inhibidor de elastasa |
EP2113503A1 (en) | 2008-04-28 | 2009-11-04 | Laboratorios Almirall, S.A. | New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors |
ES2609294T5 (es) * | 2008-06-10 | 2021-12-01 | Meadwestvaco Calmar Gmbh | Cabeza de descarga de fluido |
EP2135632A1 (de) * | 2008-06-20 | 2009-12-23 | Boehringer Ingelheim International Gmbh | Inhalator |
CA2730037A1 (en) | 2008-07-10 | 2010-01-14 | Boehringer Ingelheim International Gmbh | Sulfone compounds which modulate the cb2 receptor |
US8680263B2 (en) | 2008-09-19 | 2014-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
CA2737639A1 (en) | 2008-09-25 | 2010-04-01 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the cb2 receptor |
DE202008015493U1 (de) | 2008-11-21 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Faltschachtel |
EP2379524A1 (en) | 2008-12-18 | 2011-10-26 | Boehringer Ingelheim International GmbH | Serotonin 5-ht2b receptor inhibitors |
UY32297A (es) | 2008-12-22 | 2010-05-31 | Almirall Sa | Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico |
DE102009003992A1 (de) | 2009-01-07 | 2010-07-08 | D2O Biosience Group Ltd., Hamilton | Verwendung von Deuteriumoxid zur Behandlung Virus-basierter Erkrankungen des Respirationstraktes |
EP3620154A1 (en) | 2009-02-06 | 2020-03-11 | University Of Southern California | Therapeutic compositions comprising monoterpenes |
US20120129820A1 (en) | 2009-02-09 | 2012-05-24 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders |
EP2221055A1 (en) | 2009-02-18 | 2010-08-25 | Almirall, S.A. | 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function |
EP2221297A1 (en) | 2009-02-18 | 2010-08-25 | Almirall, S.A. | 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases |
EP2226323A1 (en) | 2009-02-27 | 2010-09-08 | Almirall, S.A. | New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives |
EP2228368A1 (en) | 2009-03-12 | 2010-09-15 | Almirall, S.A. | Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one |
WO2010103384A1 (en) * | 2009-03-13 | 2010-09-16 | Nucitec S.A. De C.V. | Compositions and methods for treatment and prevention of cardiovascular disease |
EP2236224B1 (de) | 2009-03-30 | 2013-03-06 | Boehringer Ingelheim International GmbH | Umformwerkzeug mit einem rotierbaren Grundkörper zum Formen einer Inhalatorkartusche und Verwendung eines solchen Umformwerkzeugs |
EP2236227B1 (de) | 2009-03-30 | 2013-12-18 | Boehringer Ingelheim International GmbH | Umformwerkzeug mit einem rotierbaren Grundkörper |
US10011906B2 (en) | 2009-03-31 | 2018-07-03 | Beohringer Ingelheim International Gmbh | Method for coating a surface of a component |
US9108011B2 (en) | 2009-04-28 | 2015-08-18 | Boehringer Ingelheim International Gmbh | Inhalation device |
EP3508239B1 (de) | 2009-05-18 | 2020-12-23 | Boehringer Ingelheim International GmbH | Adapter, inhalationseinrichtung und zerstäuber |
US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
US8383615B2 (en) | 2009-06-16 | 2013-02-26 | Boehringer Ingelheim International Gmbh | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor |
US9084660B2 (en) * | 2009-06-25 | 2015-07-21 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
WO2011005645A1 (en) | 2009-07-06 | 2011-01-13 | Boehringer Ingelheim International Gmbh | Polymorph of [4,6-bis(dimethylamino)-2-(4-{[4-(trifluoromethyl)benzoyl]amino}benzyl)pyrimidin-5-yl] |
US8383651B2 (en) | 2009-09-22 | 2013-02-26 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
DE102009051570B3 (de) * | 2009-10-23 | 2011-06-22 | Ing. Erich Pfeiffer GmbH, 78315 | Austragvorrichtung |
EP2322176A1 (en) | 2009-11-11 | 2011-05-18 | Almirall, S.A. | New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives |
JP2013512239A (ja) | 2009-11-24 | 2013-04-11 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ピリミジン−5−イル酢酸誘導体の新規な塩の形態 |
AU2010324980A1 (en) | 2009-11-24 | 2012-05-03 | Boehringer Ingelheim International Gmbh | Process for preparing a polymorph of the choline salt of a pyrimidin-5-yl acetic acid derivative |
UA107097C2 (en) | 2009-11-25 | 2014-11-25 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Dispenser |
WO2011064163A1 (en) * | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9315454B2 (en) | 2010-01-15 | 2016-04-19 | Boehringer Ingelheim International Gmbh | Compounds which modulate the CB2 receptor |
EP2534069B1 (en) * | 2010-02-10 | 2015-08-26 | S.C. Johnson & Son, Inc. | Overcap for an aerosol container |
BR112012022209A2 (pt) | 2010-03-03 | 2017-06-06 | Neonc Tech Inc | composições farmacêuticas compreendendo monoterpenos |
WO2011109324A1 (en) | 2010-03-05 | 2011-09-09 | Boehringer Ingelheim International Gmbh | Tetrazole compounds which selectively modulate the cb2 receptor |
EP2380890A1 (en) | 2010-04-23 | 2011-10-26 | Almirall, S.A. | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors |
EP2381237B1 (de) | 2010-04-23 | 2019-06-19 | Boehringer Ingelheim microParts GmbH | Verfahren und Vorrichtung zur Bestimmung der Arbeitsweise einer Dosiervorrichtung |
CN101839227B (zh) * | 2010-04-30 | 2012-07-04 | 浦坚 | 一种泵及便携式水净化设备 |
EP2386555A1 (en) | 2010-05-13 | 2011-11-16 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities |
EP2394998A1 (en) | 2010-05-31 | 2011-12-14 | Almirall, S.A. | 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors |
WO2011154295A2 (de) | 2010-06-08 | 2011-12-15 | Boehringer Ingelheim International Gmbh | Medizinisches gerät mit zählwerk mit voreingestelltem zählbereich gerät mit zählwerksvariation |
JP5874724B2 (ja) | 2010-06-24 | 2016-03-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
WO2012009702A1 (en) | 2010-07-15 | 2012-01-19 | Corinthian Ophthalmic, Inc. | Method and system for performing remote treatment and monitoring |
CA2805426C (en) | 2010-07-15 | 2020-03-24 | Corinthian Ophthalmic, Inc. | Drop generating device |
WO2012009696A2 (en) | 2010-07-15 | 2012-01-19 | Corinthian Ophthalmic, Inc. | Ophthalmic drug delivery |
JP5900494B2 (ja) | 2010-07-16 | 2016-04-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医療器具用フィルタシステム |
US8846936B2 (en) | 2010-07-22 | 2014-09-30 | Boehringer Ingelheim International Gmbh | Sulfonyl compounds which modulate the CB2 receptor |
US20160038600A1 (en) | 2012-08-03 | 2016-02-11 | Neonc Technologies Inc. | Pharmaceutical compositions comprising poh derivatives |
BR112013004698B1 (pt) | 2010-08-27 | 2022-03-22 | Neonc Technologies Inc. | Composições farmacêuticas compreendendo derivados de poh |
DE102010045059A1 (de) | 2010-09-10 | 2012-03-15 | F. Holzer Gmbh | Dosiervorrichtung |
EP2441755A1 (en) | 2010-09-30 | 2012-04-18 | Almirall, S.A. | Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors |
DE102010048085A1 (de) * | 2010-10-04 | 2012-04-05 | Ing. Erich Pfeiffer Gmbh | Austragvorrichtung |
EP2447694B1 (de) | 2010-10-28 | 2014-05-21 | Boehringer Ingelheim Pharma GmbH & Co. KG | Prüfleck zur Überprüfung von Leckagemesssystemen |
JP2013542255A (ja) | 2010-11-10 | 2013-11-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ミネラルコルチコイド受容体アンタゴニストとしてのピリジル尿素 |
EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
EP2463289A1 (en) | 2010-11-26 | 2012-06-13 | Almirall, S.A. | Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors |
DK2651864T3 (en) | 2010-12-17 | 2016-09-05 | Neonc Tech Inc | Methods and devices for use of isoperillylalkohol |
EP2489663A1 (en) | 2011-02-16 | 2012-08-22 | Almirall, S.A. | Compounds as syk kinase inhibitors |
EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
EP2518070A1 (en) | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Pyrrolotriazinone derivatives as PI3K inhibitors |
EP2518071A1 (en) | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Imidazopyridine derivatives as PI3K inhibitors |
US8590614B2 (en) | 2011-05-03 | 2013-11-26 | Halliburton Energy Services, Inc. | High pressure stimulation pump |
US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
EP2526945A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | New CRTH2 Antagonists |
EP2527344A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases |
EP2548863A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists. |
EP2548876A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists |
EP2554544A1 (en) | 2011-08-01 | 2013-02-06 | Almirall, S.A. | Pyridin-2(1h)-one derivatives as jak inhibitors |
EP2578570A1 (en) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis. |
EP2592077A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
EP2592078A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
WO2013090468A1 (en) | 2011-12-12 | 2013-06-20 | Corinthian Ophthalmic, Inc. | High modulus polymeric ejector mechanism, ejector device, and methods of use |
WO2013127738A1 (de) * | 2012-02-28 | 2013-09-06 | Boehringer Ingelheim International Gmbh | Neue treibgashaltige tiotropium-formulierung |
JP6174056B2 (ja) * | 2012-03-09 | 2017-08-02 | ベクチュラ・ゲーエムベーハー | 吸入用装置及び吸入用装置のための混合流路 |
EP2641900A1 (en) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor. |
US9415401B2 (en) | 2012-04-04 | 2016-08-16 | Alternative Packaging Solutions Llc | One turn actuated duration spray pump mechanism |
US9220852B2 (en) | 2012-04-10 | 2015-12-29 | Boehringer Ingelheim Microparts Gmbh | Method for producing trench-like depressions in the surface of a wafer |
WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
WO2014060431A1 (en) | 2012-10-16 | 2014-04-24 | Almirall, S.A. | Pyrrolotriazinone derivatives as pi3k inhibitors |
EP2738172A1 (en) | 2012-11-28 | 2014-06-04 | Almirall, S.A. | New bicyclic compounds as crac channel modulators |
TWM450427U (zh) * | 2012-12-14 | 2013-04-11 | Microbase Technology Corp | 控制定量液體之霧化裝置 |
BR112015013628A2 (pt) | 2012-12-18 | 2017-07-11 | Almirall Sa | derivados de carbamato de ciclo-hexila e quinuclidinila tendo atividades agonista adrenérgica de beta2 e antagonista muscarínica de m3 |
NZ706573A (en) | 2012-12-21 | 2019-11-29 | Boehringer Ingelheim Vetmedica Gmbh | Ciclesonide for the treatment of airway disease in horses |
TWM458224U (zh) * | 2012-12-21 | 2013-08-01 | Microbase Technology Corp | 旋動式霧化裝置 |
LT2934544T (lt) | 2012-12-21 | 2019-02-25 | Boehringer Ingelheim Vetmedica Gmbh | Farmacinė kompozicija, apimanti ciklezonidą |
AR094797A1 (es) | 2013-02-15 | 2015-08-26 | Almirall Sa | Derivados de pirrolotriazina como inhibidores de pi3k |
EP2803668A1 (en) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles |
GB2514893B (en) * | 2013-06-04 | 2017-12-06 | Nicoventures Holdings Ltd | Container |
EP2848615A1 (en) | 2013-07-03 | 2015-03-18 | Almirall, S.A. | New pyrazole derivatives as CRAC channel modulators |
EP3030298B1 (en) | 2013-08-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Nebulizer |
ES2836977T3 (es) | 2013-08-09 | 2021-06-28 | Boehringer Ingelheim Int | Nebulizador |
CA2913811C (en) | 2013-08-20 | 2022-06-07 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
CA2913828C (en) | 2013-08-20 | 2022-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
CA3129707C (en) | 2013-08-20 | 2023-04-25 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
US10292424B2 (en) * | 2013-10-31 | 2019-05-21 | Rai Strategic Holdings, Inc. | Aerosol delivery device including a pressure-based aerosol delivery mechanism |
EP2893947A1 (de) | 2014-01-10 | 2015-07-15 | Boehringer Ingelheim International Gmbh | Zerstäuber |
ES2954961T3 (es) | 2014-05-07 | 2023-11-27 | Boehringer Ingelheim Int | Unidad, nebulizador y método |
ES2874029T3 (es) | 2014-05-07 | 2021-11-04 | Boehringer Ingelheim Int | Nebulizador |
UA121114C2 (uk) * | 2014-05-07 | 2020-04-10 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Небулайзер, індикаторний пристрій і контейнер |
US10610651B2 (en) | 2014-06-09 | 2020-04-07 | Aerami Therapeutics, Inc. | Self-puncturing liquid drug cartridges and associated dispenser |
KR102618119B1 (ko) | 2014-06-18 | 2023-12-27 | 베링거잉겔하임베트메디카게엠베하 | 말의 기도 질환의 치료를 위한 무스카린 길항제 및 이의 병용물 |
US20160051396A1 (en) * | 2014-08-21 | 2016-02-25 | Eliezer Nussbaum | Sleep apnea device to positively block exhaling and method of use |
US10603451B2 (en) | 2014-11-20 | 2020-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Container for an inhaler |
CA2973669C (en) | 2015-01-12 | 2021-12-14 | Sca Hygiene Products Ab | A pump for a system for dispensing a liquid as a spray, a spray nozzle unit, a system for dispensing a liquid as a spray and a method for dispensing a liquid as a spray |
CN112142749A (zh) | 2015-02-12 | 2020-12-29 | NeOnc技术股份有限公司 | 紫苏醇衍生物、药物组合物及其用途 |
EP3061501A1 (en) | 2015-02-27 | 2016-08-31 | Rottapharm Ltd. | Composition for the treatment of acne |
CN107690412B (zh) | 2015-04-06 | 2020-05-05 | 约翰逊父子公司 | 分配系统 |
US10214509B2 (en) | 2015-04-21 | 2019-02-26 | Almirall, S.A. | Amino-substituted heterocyclic derivatives as sodium channel inhibitors |
WO2016202800A1 (en) | 2015-06-16 | 2016-12-22 | Almirall, S.A. | Pyrrolotriazinone derivatives as pi3k inhibitors |
EP3117825A1 (en) | 2015-07-16 | 2017-01-18 | Rottapharm S.p.A. | Oral formulation comprising berberine and morus alba extract |
DE102015213814A1 (de) * | 2015-07-22 | 2017-01-26 | Robert Bosch Gmbh | Einspritzventil, Abgasnachbehandlungssystem |
WO2017095363A1 (en) * | 2015-11-30 | 2017-06-08 | Nifco America Corp. | A check valve structure |
PL3407944T3 (pl) * | 2016-01-25 | 2020-06-01 | Boehringer Ingelheim International Gmbh | Nebulizator |
EP3202709B1 (de) | 2016-02-04 | 2019-04-10 | Boehringer Ingelheim microParts GmbH | Abformwerkzeug mit magnethalterung |
CN107362140A (zh) * | 2016-05-11 | 2017-11-21 | 广东东阳光药业有限公司 | 喷雾剂以及喷雾组件 |
EP4035719A1 (de) | 2016-09-15 | 2022-08-03 | Softhale NV | Ventil, insbesondere für eine vorrichtung zur verabreichung eines flüssigen medikaments, sowie eine entsprechende vorrichtung zur verabreichung eines flüssigen medikaments |
CN110022921B (zh) * | 2016-09-30 | 2021-10-19 | 索芙特海尔公司 | 将液态活性物质雾化成气溶胶的雾化器以及相应的方法 |
CN108057151B (zh) * | 2016-11-06 | 2021-04-27 | 微邦科技股份有限公司 | 高压液体传输装置 |
US10858305B2 (en) | 2016-11-30 | 2020-12-08 | Neonc Technologies, Inc. | Perillyl alcohol-3-bromopyruvate conjugate and methods of treating cancer |
EP4209238A1 (en) | 2016-12-21 | 2023-07-12 | Boehringer Ingelheim International GmbH | Nebulizer and cartridge |
CN111093742B (zh) | 2017-06-10 | 2022-09-16 | 艾诺维亚股份有限公司 | 用于处理流体并将流体输送到眼睛的方法和设备 |
WO2018234527A1 (en) | 2017-06-22 | 2018-12-27 | Softhale Nv | PIRFENIDONE AEROSOL ADMINISTRATION |
TW201919682A (zh) | 2017-08-08 | 2019-06-01 | 西班牙商阿爾米雷爾有限公司 | 活化Nrf2路徑的新穎化合物 |
CN107472685B (zh) * | 2017-09-22 | 2023-06-23 | 中山市陶净科技有限公司 | 应用于液体雾化器上的加压装置以及液体雾化器 |
US10617832B2 (en) | 2017-11-22 | 2020-04-14 | Southwest Research Institute | High precision, low dose atomizer |
US10968031B2 (en) | 2017-12-27 | 2021-04-06 | Sulzer Mixpac Ag | Piston for a collapsible cartridge |
CA3225993A1 (en) | 2018-02-08 | 2019-08-15 | University Of Southern California | The use of monoterpene, sesquiterpene, or their derivatives to permeabilize the blood brain barrier |
EP3563894B1 (en) | 2018-05-04 | 2021-12-22 | Boehringer Ingelheim International GmbH | Nebulizer and container |
FR3083721B1 (fr) * | 2018-07-12 | 2020-12-18 | Aptar France Sas | Dispositif de distribution de produit fluide et son procede de remplissage et de bouchage. |
WO2020016135A1 (en) * | 2018-07-16 | 2020-01-23 | Softhale Nv | Improved inhalation device |
CN109000011B (zh) * | 2018-08-14 | 2019-08-02 | 上海交通大学 | 用于冷启动微型高压气体的针式隔离阀 |
MX2021003104A (es) * | 2018-09-14 | 2021-08-11 | Israel Olegnowicz | Sello de fluido que tiene múltiples diámetros. |
WO2020064341A1 (en) * | 2018-09-27 | 2020-04-02 | Shl Medical Ag | Tensioning arrangement for aerosol dispenser and aerosol dispenser |
WO2020064372A1 (en) | 2018-09-27 | 2020-04-02 | Shl Medical Ag | Activation mechanism for an aerosol dispenser |
WO2020064343A1 (en) * | 2018-09-27 | 2020-04-02 | Shl Medical Ag | Locking mechanism for an aerosol dispenser |
PE20212261A1 (es) | 2019-03-14 | 2021-11-29 | Om Pharma Sa | Extractos bacterianos estables como farmacos |
GB2585206B (en) | 2019-07-01 | 2021-08-11 | Merxin Ltd | Portable inhaler |
CN110454353B (zh) * | 2019-09-16 | 2024-04-09 | 西南石油大学 | 复合驱动往复泵 |
CN110665670A (zh) * | 2019-10-22 | 2020-01-10 | 深圳贵之族生科技有限公司 | 一种电磁阀控制的液体雾化喷涂装置 |
WO2021101619A1 (en) * | 2019-11-18 | 2021-05-27 | Kx Technologies Llc | Push filter with floating key lock |
US20230033224A1 (en) | 2020-01-10 | 2023-02-02 | Boehringer Ingelheim Vetmedica Gmbh | Ciclesonide for ameliorating quality of life (qol) in equines |
EP4132484A1 (en) | 2020-04-10 | 2023-02-15 | Galenus G.H. AG | Composition comprising resveratrol |
CN113679910A (zh) * | 2020-05-19 | 2021-11-23 | 顾瑜 | 雾化装置 |
US20210393663A1 (en) * | 2020-06-23 | 2021-12-23 | Cai Gu Huang | Pharmaceutical formulation containing active metabolites of remdesivir or its analog for inhalation |
WO2021262648A1 (en) * | 2020-06-23 | 2021-12-30 | Anovent Pharmaceutical (U.S.), Llc | Preparation of a pharmaceutical composition of olodaterol and budesonide |
AU2021314977A1 (en) | 2020-07-31 | 2023-03-02 | Chemo Research, S.L. | Combination therapy for inhalation administration |
WO2022043481A1 (en) | 2020-08-28 | 2022-03-03 | Universität Linz | Use of leoligin in the prevention of tissue damage |
CN113339226A (zh) * | 2021-01-13 | 2021-09-03 | 李江安 | 一种用于聚苯颗粒浆料泵送的装置 |
KR102583625B1 (ko) * | 2021-02-10 | 2023-09-26 | 이형주 | 피부에 침투된 이물질 흡입 장치 |
EP4109066A1 (de) | 2021-06-25 | 2022-12-28 | Harro Höfliger Verpackungsmaschinen GmbH | Vorrichtung zum prüfen der dichtigkeit einer pumpenbaugruppe für hochdrucksprühapplikatoren |
DE202021002812U1 (de) | 2021-08-31 | 2021-09-15 | Harro Höfliger Verpackungsmaschinen GmbH | Vorrichtung zum Prüfen von an Kapillaren befestigten Hochdruckrückschlagventilen, insbesondere für den Einsatz in Sprühapplikatoren |
CN113819291B (zh) * | 2021-11-25 | 2022-02-08 | 四川宏华电气有限责任公司 | 一种往复泵免敲击阀盖装置 |
CN115212035B (zh) * | 2022-07-05 | 2023-05-26 | 福建恒捷实业有限公司 | 一种用于医疗的仿棉差异化环保锦纶纤维生产工艺 |
Family Cites Families (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US362678A (en) * | 1887-05-10 | sutton | ||
AT52014B (de) * | 1909-03-03 | 1912-02-10 | Georg Wilhelm Franz Koopmann | Pumpe. |
US1035261A (en) * | 1912-02-16 | 1912-08-13 | Hermann Strumpf | Atomizer. |
GB224531A (ja) * | 1923-11-08 | 1925-10-08 | Ludwig Le Bret | |
GB310818A (en) * | 1928-04-30 | 1930-06-19 | Charles Mayer | Piston pump more specially intended to medical purposes |
US2322913A (en) * | 1939-04-22 | 1943-06-29 | Frank C Best | Pump |
US2550840A (en) * | 1946-09-24 | 1951-05-01 | Universal Properties Inc | Valve control for pressure fluid containers |
NL296493A (ja) * | 1962-08-14 | |||
GB1100024A (en) * | 1963-10-30 | 1968-01-24 | Janusz Gutkowski | Improvements in or relating to reciprocating pumps and compressors |
US3317002A (en) * | 1965-02-08 | 1967-05-02 | Walker Mfg Co | Fluid distributing system |
GB1140422A (en) * | 1965-03-26 | 1969-01-22 | Lucas Industries Ltd | Lubricating devices |
GB1131918A (en) * | 1965-05-06 | 1968-10-30 | Murray Budd Burgess | Jet injector |
US3319894A (en) * | 1965-08-10 | 1967-05-16 | Diamond Int Corp | Liquid dispenser |
DE1475174A1 (de) * | 1965-09-20 | 1969-01-16 | Afa Corp | Fluessigkeitssprayvorrichtung |
US3361069A (en) * | 1966-03-07 | 1968-01-02 | Conelec Inc | Electronically controlled electromagnetic pump system |
DE1503396A1 (de) * | 1966-11-26 | 1970-07-16 | Bosch Gmbh Robert | Luftpumpe,insbesondere Vakuumpumpe |
US3396874A (en) * | 1967-05-15 | 1968-08-13 | Afa Corp | Positive action dispensing valve |
GB1239855A (en) * | 1969-01-30 | 1971-07-21 | Pye Ltd | Improvements in or relating to liquid injectors for medical respirators |
US3514017A (en) * | 1969-03-03 | 1970-05-26 | Afa Corp | Pressure regulating structure for piston pump |
US3575322A (en) * | 1969-03-21 | 1971-04-20 | Union Carbide Corp | Metering aerosol actuator with downstroke discharge |
US3605738A (en) * | 1969-06-20 | 1971-09-20 | Paul J Ciranna | Medicinal spray device |
US3647143A (en) * | 1970-04-06 | 1972-03-07 | Champion Spark Plug Co | Atomizer |
FR2106841A5 (ja) * | 1970-09-25 | 1972-05-05 | Saporta Jose | |
US3718908A (en) * | 1970-11-30 | 1973-02-27 | R Bloomstein | Signature storage and retrieval system |
US3746251A (en) | 1971-04-27 | 1973-07-17 | Bernardi Brothers Inc | Load shifting apparatus |
JPS5425245B1 (ja) * | 1971-05-08 | 1979-08-27 | ||
US3838686A (en) * | 1971-10-14 | 1974-10-01 | G Szekely | Aerosol apparatus for inhalation therapy |
BE792243A (fr) * | 1971-12-23 | 1973-03-30 | Baxter Laboratories Inc | Piege a bulles pour l'enlevement de bulles hors d'un fluide biologique dans des conditions assurant la sterilite |
BE795375A (fr) * | 1972-02-14 | 1973-08-13 | Thiokol Chemical Corp | Atomiseur |
US3797748A (en) * | 1972-03-30 | 1974-03-19 | T Nozawa | Liquid spraying device |
US3901414A (en) * | 1972-07-06 | 1975-08-26 | Nicholas G Capra | Liquid dispenser |
US3792800A (en) * | 1972-07-06 | 1974-02-19 | N Capra | Liquid dispenser |
US3818908A (en) * | 1972-08-07 | 1974-06-25 | Riker Laboratories Inc | Medicament dispenser |
JPS4955101U (ja) * | 1972-08-21 | 1974-05-15 | ||
US3933279A (en) * | 1972-11-28 | 1976-01-20 | Ciba-Geigy Corporation | Aerosol dispenser for fluid products comprising a piston pump assembly for generating compressed air |
CH588896A5 (ja) * | 1973-10-31 | 1977-06-15 | Ciba Geigy Ag | |
US3878973A (en) * | 1973-10-31 | 1975-04-22 | Ciba Geigy Corp | Metered dose dispenser |
CA1008825A (en) * | 1974-03-28 | 1977-04-19 | William E. Warren | Pump assembly for an atomizing piston pump |
US3995772A (en) * | 1975-07-07 | 1976-12-07 | Liautaud James P | Non-pressurized fluid product dispenser |
CA1099674A (en) * | 1975-12-05 | 1981-04-21 | Gerald A. Rooney | Manually operated liquid dispensing device |
SE408265B (sv) | 1975-12-12 | 1979-06-05 | Draco Ab | Anordning for koldioxiddriven endosaerosol, avsedd for inhalering |
US4132359A (en) * | 1976-04-09 | 1979-01-02 | Yoshino Kogyosho Co., Ltd. | Manually operative atomizer |
US4138039A (en) * | 1976-10-04 | 1979-02-06 | Leeds And Micallef | Pump actuating system |
US4077569A (en) * | 1976-10-04 | 1978-03-07 | Teledyne Industries, Inc. | Fluid-flow pulsator |
CA1077001A (en) * | 1976-10-21 | 1980-05-06 | Winfried J. Werding | Appliance for discharging gaseous liquid or pasty product, and process of its manufacture |
US4131235A (en) * | 1976-11-01 | 1978-12-26 | Irrigation Specialties Company | Dual-function valve |
US4174055A (en) * | 1977-04-20 | 1979-11-13 | James D. Pauls & J. Claybrook Lewis & Associates, Ltd. | Non-aerosol pressure dispenser |
JPS53141907A (en) * | 1977-05-17 | 1978-12-11 | Jidosha Kiki Co Ltd | Electromagnetic pump |
US4183449A (en) * | 1978-01-09 | 1980-01-15 | The Afa Corporation | Manually operated miniature atomizer |
US4271875A (en) * | 1978-09-21 | 1981-06-09 | Philip Meshberg | Dispenser adapted for fast pressure filling |
US4345718A (en) * | 1979-04-23 | 1982-08-24 | William Horvath | Manually actuated trigger sprayer |
US4602726A (en) * | 1979-12-31 | 1986-07-29 | George Goda | Dispensing device |
US4402432A (en) * | 1980-02-13 | 1983-09-06 | Corsette Douglas Frank | Leak-proof dispensing pump |
DE3007512C2 (de) * | 1980-02-28 | 1982-04-29 | Fa. Hermann Heye, 3063 Obernkirchen | Vorrichtung zum Aufbringen einer Schmier- oder Trennflüssigkeit auf ein Glasformmaschinenteil |
DE3166709D1 (en) * | 1980-08-04 | 1984-11-22 | Fisons Plc | Inhalation device for administering medicaments |
GB2096468B (en) | 1981-04-03 | 1984-11-14 | Yeda Res & Dev | Improvement in or relating to an apparatus for medical treatment |
US4441634A (en) * | 1982-01-13 | 1984-04-10 | Philip Meshberg | Dispenser adapted for fast pressure filling |
FR2521036A1 (fr) * | 1982-02-05 | 1983-08-12 | Valois Sa | Dispositif de projection de doses precises d'aerosol |
US4771769A (en) * | 1982-12-20 | 1988-09-20 | Schering Corporation | Hand held metered spray dispenser |
DE3339180C2 (de) * | 1983-10-28 | 1993-10-14 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
US4623337A (en) * | 1984-03-08 | 1986-11-18 | Alpha Group, Inc. | Liquid dispensing apparatus |
JPH0713390Y2 (ja) * | 1984-08-29 | 1995-03-29 | 昭和電線電纜株式会社 | ケ−ブル引留端部 |
US4693675A (en) * | 1986-01-16 | 1987-09-15 | The Pharmasol Corporation | Non-throttling discharge pump |
US4844299A (en) * | 1986-07-31 | 1989-07-04 | Pentel Kabushiki Kaisha | Fluid discharge device |
US4819834A (en) * | 1986-09-09 | 1989-04-11 | Minnesota Mining And Manufacturing Company | Apparatus and methods for delivering a predetermined amount of a pressurized fluid |
GB8629982D0 (en) * | 1986-12-16 | 1987-01-28 | English Glass Co Ltd | Dispenser pump |
AU1059688A (en) * | 1986-12-17 | 1988-07-15 | Microvol Limited | Pressurised metering dispenser |
US4896832A (en) * | 1987-09-07 | 1990-01-30 | Bespak Plc | Dispensing apparatus for metered quantities of pressurised fluid |
US4842198A (en) * | 1987-10-26 | 1989-06-27 | Chang Shih Chih | Device for damage protection against local flooding caused by sprinkler failure |
DE3803366A1 (de) * | 1988-02-05 | 1989-08-17 | Deussen Stella Kg | Vorrichtung zum ausgeben einer dosierten menge von fliessfaehigem gut aus einem behaelter, insbesondere fluessigem medikament aus einer arzneimittelflasche |
US4892232A (en) * | 1988-07-25 | 1990-01-09 | Martin James H | Unit dose dispenser |
DE3901032C1 (ja) * | 1989-01-14 | 1990-02-08 | Danfoss A/S, Nordborg, Dk | |
ES2043306T3 (es) * | 1989-05-31 | 1993-12-16 | Conceptair Anstalt | Procedimiento y dispositivo electrico, electronico y mecanico para distribuir, dosificr o difundir, en fase liquida o gaseosa, aromas, medicanmentos y otros productos liquidos o viscosos. |
SG45171A1 (en) * | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
GB2243880B (en) * | 1990-05-01 | 1994-03-16 | Bespak Plc | Dispensing device |
FR2663909B1 (fr) * | 1990-06-27 | 1994-01-28 | Valois | Dispositif destine a contenir un produit liquide ou pateux a distribuer sans reprise d'air, et son procede de fabrication. |
US5161574A (en) * | 1990-08-20 | 1992-11-10 | Intevep, S.A. | Maximum operation angle single plug and puppet type retention valves |
DE9013630U1 (ja) * | 1990-09-28 | 1991-01-31 | Speck-Kolbenpumpenfabrik Otto Speck Gmbh & Co. Kg, 8192 Geretsried, De | |
US5127579A (en) * | 1990-11-06 | 1992-07-07 | Mobacc B. V. | Low propellant aerosol spray head |
IL100224A (en) * | 1990-12-04 | 1994-10-21 | Dmw Tech Ltd | Spray nozzle |
DE69117193T2 (de) * | 1990-12-04 | 1996-06-27 | Dmw Tech Ltd | Düsenvorrichtung zum verhindern des rückflusses |
GB9114080D0 (en) * | 1991-06-28 | 1991-08-14 | Weston Terence E | Atomising valve |
ES2119794T3 (es) * | 1991-06-28 | 1998-10-16 | Weston Medical Ltd | Boquilla de atomizacion. |
DE4139555A1 (de) * | 1991-09-18 | 1993-03-25 | Gaplast Gmbh | Behaelter |
IL107120A (en) * | 1992-09-29 | 1997-09-30 | Boehringer Ingelheim Int | Atomising nozzle and filter and spray generating device |
FR2699390B1 (fr) * | 1992-12-23 | 1995-02-10 | Sodex Hexotol Sa | Appareil distributeur pour produits liquides. |
JPH07189922A (ja) * | 1993-12-28 | 1995-07-28 | Seikosha Co Ltd | インクジェットプリンタ用インク吸引ポンプ |
JPH07223689A (ja) * | 1994-02-03 | 1995-08-22 | Hosokawa Yoko:Kk | 液体内容物吐出容器 |
EP0688608A1 (en) * | 1994-03-25 | 1995-12-27 | GUALA S.p.A. | An atomizer device for manually operated pumps |
GB2291135B (en) * | 1994-07-06 | 1998-02-25 | Boehringer Ingelheim Kg | Device for dispensing fluid |
DE4428434A1 (de) * | 1994-08-11 | 1996-02-15 | Boehringer Ingelheim Kg | Verschlußkappe und Verfahren zur gasblasenfreien Füllung von Behältern |
JP3224480B2 (ja) * | 1994-09-30 | 2001-10-29 | キヤノン株式会社 | カラー画像処理装置 |
US5505343A (en) * | 1994-10-19 | 1996-04-09 | Knickerbocker; Michael G. | Manually actuated pump |
US5503306A (en) * | 1994-10-19 | 1996-04-02 | Aptar Group, Inc. | Manually actuated pump |
DE19536902A1 (de) | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
-
1995
- 1995-10-04 DE DE19536902A patent/DE19536902A1/de not_active Ceased
-
1996
- 1996-04-10 UA UA98042211A patent/UA54402C2/uk unknown
- 1996-10-02 HR HR960448A patent/HRP960448B1/xx not_active IP Right Cessation
- 1996-10-03 EG EG89496A patent/EG21374A/xx active
- 1996-10-03 YU YU53996A patent/YU49228B/sh unknown
- 1996-10-03 ZA ZA9608317A patent/ZA968317B/xx unknown
- 1996-10-03 UY UY24339A patent/UY24339A1/es not_active IP Right Cessation
- 1996-10-03 CO CO96052654A patent/CO4560418A1/es unknown
- 1996-10-04 SK SK426-98A patent/SK283515B6/sk not_active IP Right Cessation
- 1996-10-04 AT AT02003525T patent/ATE352379T1/de active
- 1996-10-04 US US08/726,219 patent/US5964416A/en not_active Expired - Lifetime
- 1996-10-04 PL PL96325961A patent/PL185631B1/pl unknown
- 1996-10-04 PL PL96356022A patent/PL185789B1/pl unknown
- 1996-10-04 DK DK96934565T patent/DK0853501T3/da active
- 1996-10-04 ES ES02003525T patent/ES2280442T3/es not_active Expired - Lifetime
- 1996-10-04 AR ARP960104602A patent/AR003794A1/es unknown
- 1996-10-04 AT AT96934565T patent/ATE248028T1/de active
- 1996-10-04 SI SI9630753T patent/SI1214985T1/sl unknown
- 1996-10-04 DK DK02003525T patent/DK1214985T3/da active
- 1996-10-04 PT PT02003525T patent/PT1214985E/pt unknown
- 1996-10-04 IL IL12363496A patent/IL123634A/en not_active IP Right Cessation
- 1996-10-04 TR TR1998/00586T patent/TR199800586T1/xx unknown
- 1996-10-04 PE PE1996000705A patent/PE29098A1/es not_active IP Right Cessation
- 1996-10-04 SI SI9630645T patent/SI0853501T1/xx unknown
- 1996-10-04 AU AU72870/96A patent/AU730797B2/en not_active Expired
- 1996-10-04 WO PCT/EP1996/004351 patent/WO1997012687A1/en active IP Right Grant
- 1996-10-04 EP EP96934565A patent/EP0853501B1/en not_active Expired - Lifetime
- 1996-10-04 KR KR10-1998-0702174A patent/KR100431011B1/ko not_active IP Right Cessation
- 1996-10-04 CZ CZ19981015A patent/CZ295103B6/cs not_active IP Right Cessation
- 1996-10-04 PT PT96934565T patent/PT853501E/pt unknown
- 1996-10-04 IL IL14022196A patent/IL140221A/xx not_active IP Right Cessation
- 1996-10-04 CN CN96197411.7A patent/CN1091660C/zh not_active Expired - Lifetime
- 1996-10-04 ES ES96934565T patent/ES2201204T3/es not_active Expired - Lifetime
- 1996-10-04 CA CA002232151A patent/CA2232151C/en not_active Expired - Lifetime
- 1996-10-04 HU HU9900741A patent/HU221232B1/hu unknown
- 1996-10-04 EP EP02003525A patent/EP1214985B1/en not_active Expired - Lifetime
- 1996-10-04 CA CA2551999A patent/CA2551999C/en not_active Expired - Lifetime
- 1996-10-04 MY MYPI96004102A patent/MY115214A/en unknown
- 1996-10-04 NZ NZ320179A patent/NZ320179A/en not_active IP Right Cessation
- 1996-10-04 CA CA2551891A patent/CA2551891C/en not_active Expired - Lifetime
- 1996-10-04 CA CA2473681A patent/CA2473681C/en not_active Expired - Lifetime
- 1996-10-04 EE EE9800107A patent/EE03519B1/xx unknown
- 1996-10-04 RU RU98108402/12A patent/RU2179075C2/ru active
- 1996-10-04 DE DE69636875T patent/DE69636875T2/de not_active Expired - Lifetime
- 1996-10-04 DE DE69629708T patent/DE69629708T2/de not_active Expired - Lifetime
- 1996-10-04 BR BR9611140A patent/BR9611140A/pt not_active IP Right Cessation
- 1996-12-27 TW TW085112161A patent/TW364041B/zh not_active IP Right Cessation
-
1997
- 1997-02-19 SA SA97170624A patent/SA97170624B1/ar unknown
-
1998
- 1998-03-24 BG BG102345A patent/BG64081B1/bg unknown
- 1998-04-03 NO NO981521A patent/NO981521L/no not_active Application Discontinuation
-
1999
- 1999-01-22 HK HK99100301A patent/HK1015304A1/xx not_active IP Right Cessation
- 1999-07-16 US US09/354,663 patent/US6402055B1/en not_active Expired - Lifetime
-
2000
- 2000-12-11 IL IL14022100A patent/IL140221A0/xx active IP Right Grant
-
2002
- 2002-05-13 US US10/143,006 patent/US6497373B2/en not_active Expired - Lifetime
- 2002-05-24 JP JP2002150712A patent/JP2003056458A/ja not_active Withdrawn
- 2002-11-13 US US10/292,470 patent/US6726124B2/en not_active Expired - Lifetime
-
2004
- 2004-03-24 US US10/807,447 patent/US6918547B2/en not_active Expired - Fee Related
-
2005
- 2005-06-24 US US11/165,496 patent/US7104470B2/en not_active Expired - Fee Related
-
2006
- 2006-08-09 US US11/463,455 patent/US20060285987A1/en not_active Abandoned
-
2007
- 2007-01-16 JP JP2007006590A patent/JP2007092762A/ja active Pending
- 2007-09-05 NO NO20074487A patent/NO20074487L/no not_active Application Discontinuation
-
2008
- 2008-10-27 JP JP2008275711A patent/JP5015896B2/ja not_active Expired - Lifetime
-
2010
- 2010-03-10 JP JP2010053741A patent/JP2010138913A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5015896B2 (ja) | 流体を加圧するための装置 | |
JP2009019637A6 (ja) | 流体を加圧するための装置 | |
JP7402291B2 (ja) | ネブライザ | |
JP3488717B6 (ja) | 霧化すベき流体に高圧を発生させるための小型化された構造の装置 | |
AU732562B2 (en) | Device for producing high pressure in a fluid in miniature |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20081028 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110623 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20110922 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20110928 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20111116 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20120524 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20120607 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20150615 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
EXPY | Cancellation because of completion of term |