JP4318856B2 - チモーゲン性核酸検出方法、および関連分子およびキット - Google Patents

チモーゲン性核酸検出方法、および関連分子およびキット Download PDF

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JP4318856B2
JP4318856B2 JP2000534677A JP2000534677A JP4318856B2 JP 4318856 B2 JP4318856 B2 JP 4318856B2 JP 2000534677 A JP2000534677 A JP 2000534677A JP 2000534677 A JP2000534677 A JP 2000534677A JP 4318856 B2 JP4318856 B2 JP 4318856B2
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nucleic acid
primer
dna
zymogen
molecule
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JP2002505117A (ja
JP2002505117A5 (enExample
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トッド・アリソン
フェリー・キャロライン・ジェイ
カーンズ・マレー
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    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/6823Release of bound markers
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6844Nucleic acid amplification reactions
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6867Replicase-based amplification, e.g. using Q-beta replicase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2000534677A 1998-03-05 1999-02-22 チモーゲン性核酸検出方法、および関連分子およびキット Expired - Fee Related JP4318856B2 (ja)

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US7689998P 1998-03-05 1998-03-05
US60/076,899 1998-03-05
PCT/IB1999/000754 WO1999045146A1 (en) 1998-03-05 1999-02-22 Zymogenic nucleic acid detection methods, and related molecules and kits

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JP2002505117A JP2002505117A (ja) 2002-02-19
JP2002505117A5 JP2002505117A5 (enExample) 2006-04-20
JP4318856B2 true JP4318856B2 (ja) 2009-08-26

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US (3) US6140055A (enExample)
EP (1) EP1062367B1 (enExample)
JP (1) JP4318856B2 (enExample)
KR (1) KR100748863B1 (enExample)
CN (1) CN1167811C (enExample)
AT (1) ATE414169T1 (enExample)
AU (1) AU768627B2 (enExample)
BR (1) BR9908567A (enExample)
CA (1) CA2321948A1 (enExample)
DE (1) DE69939896D1 (enExample)
IL (2) IL138126A0 (enExample)
WO (1) WO1999045146A1 (enExample)
ZA (1) ZA991772B (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003624A1 (en) * 1992-08-04 1994-02-17 Auerbach Jeffrey I Methods for the isothermal amplification of nucleic acid molecules
US6261808B1 (en) * 1992-08-04 2001-07-17 Replicon, Inc. Amplification of nucleic acid molecules via circular replicons
CA2321948A1 (en) 1998-03-05 1999-09-10 Johnson & Johnson Research Pty. Limited Zymogenic nucleic acid detection methods, and related molecules and kits
DE19811618C1 (de) * 1998-03-17 2000-08-31 Andreas Jenne Ribozym codierende DNA und ein Oligonucleotidsubstrat enthaltende Zusammensetzung und Verfahren zur Messung von Transkriptionsraten
AUPQ495700A0 (en) * 2000-01-05 2000-02-03 Johnson & Johnson Research Pty. Limited Method for concurrent amplification and real time detection of polymorphic nucleic acid sequences
US7205129B1 (en) * 2000-02-28 2007-04-17 Qiagen Gmbh Method for reducing artifacts in nucleic acid amplification
AU2001268481A1 (en) * 2000-06-15 2001-12-24 Board Of Regents, The University Of Texas System Regulatable, catalytically active nucleic acids
US7125660B2 (en) 2000-09-13 2006-10-24 Archemix Corp. Nucleic acid sensor molecules and methods of using same
WO2003014375A2 (en) * 2001-08-09 2003-02-20 Archemix Corporation Nucleic acid sensor molecules and methods of using same
US7297485B2 (en) * 2001-10-15 2007-11-20 Qiagen Gmbh Method for nucleic acid amplification that results in low amplification bias
US6617137B2 (en) * 2001-10-15 2003-09-09 Molecular Staging Inc. Method of amplifying whole genomes without subjecting the genome to denaturing conditions
US7955795B2 (en) * 2003-06-06 2011-06-07 Qiagen Gmbh Method of whole genome amplification with reduced artifact production
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US8043834B2 (en) 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
KR100890885B1 (ko) 2003-03-31 2009-03-31 에프. 호프만-라 로슈 아게 일본 뇌염 바이러스 혈청군의 구성원을 포함하는, 특정플라비바이러스 검출용 조성물 및 방법
JP2007534308A (ja) * 2003-11-19 2007-11-29 アレロジック・バイオサイエンシズ・コーポレーション 複数のフルオロフォアで標識したオリゴヌクレオチド
US20050250134A1 (en) * 2004-03-02 2005-11-10 Dawei Sheng Fluorescent energy transfer labeled nucleic acid substrates and methods of use thereof
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
WO2006086499A2 (en) * 2005-02-08 2006-08-17 Applera Corporation Nucleozymes and methods of use
EP1863908B1 (de) 2005-04-01 2010-11-17 Qiagen GmbH Reverse transkription und amplifikation von rna bei simultaner degradierung von dna
US20070015180A1 (en) * 2005-05-02 2007-01-18 Stratagene California Oligonucleotide probe/primer compositions and methods for polynucleotide detection
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
BRPI0616466B1 (pt) 2005-10-07 2021-01-26 Johnson & Johnson Research Pty Limited composição de enzimas de ácido nucleico multicomponentes (mnazima), métodos para detectar a presença de pelo menos um facilitador de combinação, um alvo e uma variante de sequência de ácidos nucléicos, métodos para fabricar uma pluraridade de mnazima, testar sequências de núcleo catalítico parcial e identificar suas posições, bem como uso de pelo menos um oligonucleotídeo
WO2007056312A2 (en) * 2005-11-07 2007-05-18 Clontech Laboratories, Inc. Universal reporter tag for nucleozyme assays
AU2006323930B2 (en) * 2005-12-07 2012-06-21 Janssen Sciences Ireland Uc Methods, plasmid vectors and primers for assessing HIV viral fitness
WO2008001376A2 (en) * 2006-06-28 2008-01-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Detection of analytes in a medium
DE102006035600B3 (de) * 2006-07-27 2007-11-08 Epigenomics Ag Verfahren zum Nachweis eines Methylierungsmusters
EP1882746A3 (en) * 2006-07-27 2008-03-19 Epigenomics AG Method for detecting a methylation pattern
KR20090098960A (ko) 2006-10-06 2009-09-18 존슨 앤드 존슨 리서치 피티와이 리미티드 분자 스위치 및 이의 이용 방법
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
WO2008122084A1 (en) 2007-04-05 2008-10-16 Johnson & Johnson Research Pty Limited Nucleic acid enzymes and complexes and methods for their use
EP2071035A1 (en) * 2007-12-13 2009-06-17 Epigenomics AG Facilitator and method for amplification
WO2010147848A2 (en) 2009-06-15 2010-12-23 Rd Biosciences, Inc. Kits and methods for selective amplification and detection of nucleic acid targets
CN101907573B (zh) * 2010-08-17 2012-08-22 复旦大学 一种高灵敏度的集成cmos光学生物芯片
WO2012034130A2 (en) 2010-09-10 2012-03-15 Qiagen Methods and compositions for nucleic acid detection
JP6088487B2 (ja) 2011-04-15 2017-03-01 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 走査リアルタイムマイクロ流体熱サイクラーと同期熱サイクリング及び走査光学検出の方法
CN104040238B (zh) 2011-11-04 2017-06-27 汉迪拉布公司 多核苷酸样品制备装置
AU2013202354A1 (en) * 2012-06-18 2014-01-16 Speedx Pty Ltd Target detection and signal amplification
CN103013953B (zh) * 2012-10-19 2014-09-17 中国科学院成都生物研究所 一种剪切dna的dna酶
CN105518156A (zh) * 2013-09-05 2016-04-20 日本电气方案创新株式会社 用于制备样品的方法和用于分析靶标的方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000159A (en) * 1974-06-28 1976-12-28 Phillips Petroleum Company Preparation of n,n-disubstituted thioamides
US5176995A (en) * 1985-03-28 1993-01-05 Hoffmann-La Roche Inc. Detection of viruses by amplification and hybridization
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
JP3276955B2 (ja) * 1988-09-30 2002-04-22 ジーン−トラック・システムス Rnaの鋳型の末端に結合したプローブ構造およびその使用方法
US5112734A (en) * 1989-05-26 1992-05-12 Gene-Trak Systems Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna
NZ314629A (en) * 1991-01-17 2000-08-25 Gen Hospital Corp Use trans-splicing ribozymes to prepare medicaments for gene therapies
GB9115909D0 (en) * 1991-07-23 1991-09-04 Nickerson Int Seed Recombinant dna
ATE217347T1 (de) * 1992-12-04 2002-05-15 Univ Yale Diagnose mittels signalverstärkung durch ein ribozym
US5436143A (en) * 1992-12-23 1995-07-25 Hyman; Edward D. Method for enzymatic synthesis of oligonucleotides
US5516664A (en) * 1992-12-23 1996-05-14 Hyman; Edward D. Enzymatic synthesis of repeat regions of oligonucleotides
KR100218726B1 (ko) * 1992-12-30 1999-09-01 김영환 고집적 반도체 소자의 접속장치 및 그 제조방법
IL105894A (en) * 1993-06-03 1997-02-18 Asher Nathan Method for the detection of nucleic acid sequence by using a detection ensemble and an amplification ensemble
US5582988A (en) * 1994-09-15 1996-12-10 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
US5807718A (en) * 1994-12-02 1998-09-15 The Scripps Research Institute Enzymatic DNA molecules
IL111857A (en) * 1994-12-02 1999-09-22 Intelligene Ltd Detection of nucleic acid sequences
MX9706501A (es) * 1995-02-27 1998-02-28 Intelligene Ltd Deteccion de biomoleculas.
AUPN245295A0 (en) * 1995-04-13 1995-05-11 Johnson & Johnson Research Pty. Limited Assay for genetic abnormalities
ATE212676T1 (de) * 1995-06-07 2002-02-15 Merck & Co Inc Dna-polymerase verlängungs assay
CA2287520C (en) * 1997-04-29 2010-12-14 The Scripps Research Institute Enzymatic dna molecules
DE19805593A1 (de) * 1998-02-12 1999-08-19 Voith Sulzer Papiertech Patent Eindicker
CA2321948A1 (en) 1998-03-05 1999-09-10 Johnson & Johnson Research Pty. Limited Zymogenic nucleic acid detection methods, and related molecules and kits

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Publication number Publication date
DE69939896D1 (de) 2008-12-24
KR100748863B1 (ko) 2007-08-13
CA2321948A1 (en) 1999-09-10
IL164182A0 (en) 2005-12-18
ATE414169T1 (de) 2008-11-15
CN1319142A (zh) 2001-10-24
EP1062367A4 (en) 2003-07-30
AU768627B2 (en) 2003-12-18
US20010001063A1 (en) 2001-05-10
JP2002505117A (ja) 2002-02-19
AU3340999A (en) 1999-09-20
CN1167811C (zh) 2004-09-22
EP1062367A1 (en) 2000-12-27
ZA991772B (en) 2000-10-12
BR9908567A (pt) 2000-12-12
US6140055A (en) 2000-10-31
EP1062367B1 (en) 2008-11-12
US6365724B2 (en) 2002-04-02
IL138126A0 (en) 2001-10-31
KR20010041591A (ko) 2001-05-25
WO1999045146A1 (en) 1999-09-10
US6201113B1 (en) 2001-03-13

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