ATE414169T1 - Methoden zur detektion von nukleinsäuren unter verwendung von zymogenen und dazugehörige kits - Google Patents
Methoden zur detektion von nukleinsäuren unter verwendung von zymogenen und dazugehörige kitsInfo
- Publication number
- ATE414169T1 ATE414169T1 AT99914694T AT99914694T ATE414169T1 AT E414169 T1 ATE414169 T1 AT E414169T1 AT 99914694 T AT99914694 T AT 99914694T AT 99914694 T AT99914694 T AT 99914694T AT E414169 T1 ATE414169 T1 AT E414169T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- methods
- target
- sample
- zymogens
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 102000010911 Enzyme Precursors Human genes 0.000 title 1
- 108010062466 Enzyme Precursors Proteins 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 230000003197 catalytic effect Effects 0.000 abstract 2
- 230000000692 anti-sense effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6867—Replicase-based amplification, e.g. using Q-beta replicase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7689998P | 1998-03-05 | 1998-03-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE414169T1 true ATE414169T1 (de) | 2008-11-15 |
Family
ID=22134859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99914694T ATE414169T1 (de) | 1998-03-05 | 1999-02-22 | Methoden zur detektion von nukleinsäuren unter verwendung von zymogenen und dazugehörige kits |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6140055A (de) |
| EP (1) | EP1062367B1 (de) |
| JP (1) | JP4318856B2 (de) |
| KR (1) | KR100748863B1 (de) |
| CN (1) | CN1167811C (de) |
| AT (1) | ATE414169T1 (de) |
| AU (1) | AU768627B2 (de) |
| BR (1) | BR9908567A (de) |
| CA (1) | CA2321948A1 (de) |
| DE (1) | DE69939896D1 (de) |
| IL (2) | IL138126A0 (de) |
| WO (1) | WO1999045146A1 (de) |
| ZA (1) | ZA991772B (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6261808B1 (en) * | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
| WO1994003624A1 (en) * | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
| CN1167811C (zh) | 1998-03-05 | 2004-09-22 | 约翰逊及约翰逊研究有限公司 | 酶原性核酸的检测方法,以及相关分子和试剂盒 |
| DE19811618C1 (de) * | 1998-03-17 | 2000-08-31 | Andreas Jenne | Ribozym codierende DNA und ein Oligonucleotidsubstrat enthaltende Zusammensetzung und Verfahren zur Messung von Transkriptionsraten |
| AUPQ495700A0 (en) * | 2000-01-05 | 2000-02-03 | Johnson & Johnson Research Pty. Limited | Method for concurrent amplification and real time detection of polymorphic nucleic acid sequences |
| US7205129B1 (en) * | 2000-02-28 | 2007-04-17 | Qiagen Gmbh | Method for reducing artifacts in nucleic acid amplification |
| AU2001268481A1 (en) * | 2000-06-15 | 2001-12-24 | Board Of Regents, The University Of Texas System | Regulatable, catalytically active nucleic acids |
| US7125660B2 (en) | 2000-09-13 | 2006-10-24 | Archemix Corp. | Nucleic acid sensor molecules and methods of using same |
| AU2002355571A1 (en) * | 2001-08-09 | 2003-02-24 | Archemix Corporation | Nucleic acid sensor molecules and methods of using same |
| US7297485B2 (en) * | 2001-10-15 | 2007-11-20 | Qiagen Gmbh | Method for nucleic acid amplification that results in low amplification bias |
| US6617137B2 (en) * | 2001-10-15 | 2003-09-09 | Molecular Staging Inc. | Method of amplifying whole genomes without subjecting the genome to denaturing conditions |
| US7955795B2 (en) * | 2003-06-06 | 2011-06-07 | Qiagen Gmbh | Method of whole genome amplification with reduced artifact production |
| US9487823B2 (en) | 2002-12-20 | 2016-11-08 | Qiagen Gmbh | Nucleic acid amplification |
| ES2524048T3 (es) | 2003-03-31 | 2014-12-03 | F. Hoffmann-La Roche Ag | Composiciones y métodos para la detección de ciertos flavivirus, incluidos los miembros del serogrupo del virus de la encefalitis japonesa |
| US8043834B2 (en) | 2003-03-31 | 2011-10-25 | Qiagen Gmbh | Universal reagents for rolling circle amplification and methods of use |
| JP2007534308A (ja) * | 2003-11-19 | 2007-11-29 | アレロジック・バイオサイエンシズ・コーポレーション | 複数のフルオロフォアで標識したオリゴヌクレオチド |
| US20050250134A1 (en) * | 2004-03-02 | 2005-11-10 | Dawei Sheng | Fluorescent energy transfer labeled nucleic acid substrates and methods of use thereof |
| US7939251B2 (en) | 2004-05-06 | 2011-05-10 | Roche Molecular Systems, Inc. | SENP1 as a marker for cancer |
| US20060211018A1 (en) * | 2005-02-08 | 2006-09-21 | Applera Corporation | Nucleozymes and methods of use |
| US8309303B2 (en) | 2005-04-01 | 2012-11-13 | Qiagen Gmbh | Reverse transcription and amplification of RNA with simultaneous degradation of DNA |
| JP2008539730A (ja) * | 2005-05-02 | 2008-11-20 | ストラタジーン カリフォルニア | オリゴヌクレオチドのプローブ／プライマー組成物、及びポリヌクレオチドの検出方法 |
| EP1762627A1 (de) | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
| DK1948822T3 (da) * | 2005-10-07 | 2011-10-17 | Johnson & Johnson Res Pty Ltd | Multikomponent-nukleinsyreenzymer og fremgangsmåder til deres anvendelse |
| WO2007056312A2 (en) * | 2005-11-07 | 2007-05-18 | Clontech Laboratories, Inc. | Universal reporter tag for nucleozyme assays |
| EP1960554B1 (de) * | 2005-12-07 | 2011-06-08 | Tibotec Pharmaceuticals | Verfahren, plasmidvektoren und primer zur beurteilung der hiv-virusfitness |
| WO2008001376A2 (en) * | 2006-06-28 | 2008-01-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Detection of analytes in a medium |
| DE102006035600B3 (de) * | 2006-07-27 | 2007-11-08 | Epigenomics Ag | Verfahren zum Nachweis eines Methylierungsmusters |
| EP1882746A3 (de) * | 2006-07-27 | 2008-03-19 | Epigenomics AG | Methode zum Nachweis eines Methylierungsmusters |
| BRPI0718137B1 (pt) | 2006-10-06 | 2016-05-10 | Johnson & Johnson Res Pty Ltd | comutadores moleculares e métodos para seu uso |
| US9938641B2 (en) * | 2006-12-18 | 2018-04-10 | Fluidigm Corporation | Selection of aptamers based on geometry |
| CN101802216B (zh) * | 2007-04-05 | 2014-12-10 | 斯比戴克斯私人有限公司 | 核酸酶和复合体及其使用方法 |
| EP2071035A1 (de) | 2007-12-13 | 2009-06-17 | Epigenomics AG | Vermittler und Verstärkungsverfahren |
| WO2010147848A2 (en) | 2009-06-15 | 2010-12-23 | Rd Biosciences, Inc. | Kits and methods for selective amplification and detection of nucleic acid targets |
| CN101907573B (zh) * | 2010-08-17 | 2012-08-22 | 复旦大学 | 一种高灵敏度的集成cmos光学生物芯片 |
| US9051606B2 (en) | 2010-09-10 | 2015-06-09 | Qiagen Gaithersburg, Inc. | Methods and compositions for nucleic acid detection |
| ES2617599T3 (es) | 2011-04-15 | 2017-06-19 | Becton, Dickinson And Company | Termociclador microfluídico de exploración en tiempo real y métodos para termociclado sincronizado y detección óptica de exploración |
| CN104040238B (zh) | 2011-11-04 | 2017-06-27 | 汉迪拉布公司 | 多核苷酸样品制备装置 |
| AU2013202354A1 (en) * | 2012-06-18 | 2014-01-16 | Speedx Pty Ltd | Target detection and signal amplification |
| CN103013953B (zh) * | 2012-10-19 | 2014-09-17 | 中国科学院成都生物研究所 | 一种剪切dna的dna酶 |
| WO2015033650A1 (ja) * | 2013-09-05 | 2015-03-12 | Ｎｅｃソリューションイノベータ株式会社 | サンプルの製造方法およびターゲットの分析方法 |
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| US4000159A (en) * | 1974-06-28 | 1976-12-28 | Phillips Petroleum Company | Preparation of n,n-disubstituted thioamides |
| US5176995A (en) * | 1985-03-28 | 1993-01-05 | Hoffmann-La Roche Inc. | Detection of viruses by amplification and hybridization |
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| JP3276955B2 (ja) * | 1988-09-30 | 2002-04-22 | ジーン−トラック・システムス | Ｒｎａの鋳型の末端に結合したプローブ構造およびその使用方法 |
| US5112734A (en) * | 1989-05-26 | 1992-05-12 | Gene-Trak Systems | Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna |
| NZ241310A (en) * | 1991-01-17 | 1995-03-28 | Gen Hospital Corp | Trans-splicing ribozymes |
| GB9115909D0 (en) * | 1991-07-23 | 1991-09-04 | Nickerson Int Seed | Recombinant dna |
| WO1994013833A1 (en) * | 1992-12-04 | 1994-06-23 | Innovir Laboratories, Inc. | Ribozyme amplified diagnostics |
| US5516664A (en) * | 1992-12-23 | 1996-05-14 | Hyman; Edward D. | Enzymatic synthesis of repeat regions of oligonucleotides |
| US5436143A (en) * | 1992-12-23 | 1995-07-25 | Hyman; Edward D. | Method for enzymatic synthesis of oligonucleotides |
| KR100218726B1 (ko) * | 1992-12-30 | 1999-09-01 | 김영환 | 고집적 반도체 소자의 접속장치 및 그 제조방법 |
| IL105894A (en) * | 1993-06-03 | 1997-02-18 | Asher Nathan | Method for the detection of nucleic acid sequence by using a detection ensemble and an amplification ensemble |
| US5582988A (en) * | 1994-09-15 | 1996-12-10 | Johnson & Johnson Clinical Diagnostics, Inc. | Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same |
| IL111857A (en) * | 1994-12-02 | 1999-09-22 | Intelligene Ltd | Detection of nucleic acid sequences |
| US5807718A (en) * | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
| MX9706501A (es) * | 1995-02-27 | 1998-02-28 | Intelligene Ltd | Deteccion de biomoleculas. |
| AUPN245295A0 (en) * | 1995-04-13 | 1995-05-11 | Johnson & Johnson Research Pty. Limited | Assay for genetic abnormalities |
| JPH11506607A (ja) * | 1995-06-07 | 1999-06-15 | メルク エンド カンパニー インコーポレーテッド | Ｄｎａポリメラーゼ伸長アッセイ |
| BRPI9809433B1 (pt) * | 1997-04-29 | 2015-09-08 | Scripps Research Inst | moléculas de dna enzimáticas |
| DE19805593A1 (de) * | 1998-02-12 | 1999-08-19 | Voith Sulzer Papiertech Patent | Eindicker |
| CN1167811C (zh) | 1998-03-05 | 2004-09-22 | 约翰逊及约翰逊研究有限公司 | 酶原性核酸的检测方法,以及相关分子和试剂盒 |
-
1999
- 1999-02-22 CN CNB998111147A patent/CN1167811C/zh not_active Expired - Fee Related
- 1999-02-22 KR KR1020007009783A patent/KR100748863B1/ko not_active Expired - Fee Related
- 1999-02-22 AT AT99914694T patent/ATE414169T1/de not_active IP Right Cessation
- 1999-02-22 US US09/253,955 patent/US6140055A/en not_active Expired - Lifetime
- 1999-02-22 JP JP2000534677A patent/JP4318856B2/ja not_active Expired - Fee Related
- 1999-02-22 WO PCT/IB1999/000754 patent/WO1999045146A1/en not_active Ceased
- 1999-02-22 IL IL13812699A patent/IL138126A0/xx not_active IP Right Cessation
- 1999-02-22 AU AU33409/99A patent/AU768627B2/en not_active Ceased
- 1999-02-22 BR BR9908567-4A patent/BR9908567A/pt not_active Application Discontinuation
- 1999-02-22 CA CA002321948A patent/CA2321948A1/en not_active Abandoned
- 1999-02-22 IL IL16418299A patent/IL164182A0/xx unknown
- 1999-02-22 DE DE69939896T patent/DE69939896D1/de not_active Expired - Fee Related
- 1999-02-22 EP EP99914694A patent/EP1062367B1/de not_active Expired - Lifetime
- 1999-03-04 ZA ZA9901772A patent/ZA991772B/xx unknown
-
2000
- 2000-08-11 US US09/637,405 patent/US6201113B1/en not_active Expired - Lifetime
- 2000-12-21 US US09/746,985 patent/US6365724B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69939896D1 (de) | 2008-12-24 |
| EP1062367B1 (de) | 2008-11-12 |
| US6201113B1 (en) | 2001-03-13 |
| ZA991772B (en) | 2000-10-12 |
| CN1167811C (zh) | 2004-09-22 |
| EP1062367A4 (de) | 2003-07-30 |
| KR20010041591A (ko) | 2001-05-25 |
| IL164182A0 (en) | 2005-12-18 |
| US20010001063A1 (en) | 2001-05-10 |
| KR100748863B1 (ko) | 2007-08-13 |
| US6365724B2 (en) | 2002-04-02 |
| BR9908567A (pt) | 2000-12-12 |
| IL138126A0 (en) | 2001-10-31 |
| AU3340999A (en) | 1999-09-20 |
| JP2002505117A (ja) | 2002-02-19 |
| AU768627B2 (en) | 2003-12-18 |
| US6140055A (en) | 2000-10-31 |
| EP1062367A1 (de) | 2000-12-27 |
| JP4318856B2 (ja) | 2009-08-26 |
| CA2321948A1 (en) | 1999-09-10 |
| WO1999045146A1 (en) | 1999-09-10 |
| CN1319142A (zh) | 2001-10-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |