CA2321948A1 - Zymogenic nucleic acid detection methods, and related molecules and kits - Google Patents
Zymogenic nucleic acid detection methods, and related molecules and kits Download PDFInfo
- Publication number
- CA2321948A1 CA2321948A1 CA002321948A CA2321948A CA2321948A1 CA 2321948 A1 CA2321948 A1 CA 2321948A1 CA 002321948 A CA002321948 A CA 002321948A CA 2321948 A CA2321948 A CA 2321948A CA 2321948 A1 CA2321948 A1 CA 2321948A1
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- Prior art keywords
- nucleic acid
- target
- primer
- zymogene
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6867—Replicase-based amplification, e.g. using Q-beta replicase
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7689998P | 1998-03-05 | 1998-03-05 | |
| US60/076,899 | 1998-03-05 | ||
| PCT/IB1999/000754 WO1999045146A1 (en) | 1998-03-05 | 1999-02-22 | Zymogenic nucleic acid detection methods, and related molecules and kits |
Publications (1)
| Publication Number | Publication Date |
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| CA2321948A1 true CA2321948A1 (en) | 1999-09-10 |
Family
ID=22134859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002321948A Abandoned CA2321948A1 (en) | 1998-03-05 | 1999-02-22 | Zymogenic nucleic acid detection methods, and related molecules and kits |
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| Country | Link |
|---|---|
| US (3) | US6140055A (enExample) |
| EP (1) | EP1062367B1 (enExample) |
| JP (1) | JP4318856B2 (enExample) |
| KR (1) | KR100748863B1 (enExample) |
| CN (1) | CN1167811C (enExample) |
| AT (1) | ATE414169T1 (enExample) |
| AU (1) | AU768627B2 (enExample) |
| BR (1) | BR9908567A (enExample) |
| CA (1) | CA2321948A1 (enExample) |
| DE (1) | DE69939896D1 (enExample) |
| IL (2) | IL138126A0 (enExample) |
| WO (1) | WO1999045146A1 (enExample) |
| ZA (1) | ZA991772B (enExample) |
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| DE19811618C1 (de) * | 1998-03-17 | 2000-08-31 | Andreas Jenne | Ribozym codierende DNA und ein Oligonucleotidsubstrat enthaltende Zusammensetzung und Verfahren zur Messung von Transkriptionsraten |
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| US7955795B2 (en) * | 2003-06-06 | 2011-06-07 | Qiagen Gmbh | Method of whole genome amplification with reduced artifact production |
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| EP1762627A1 (de) | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
| BRPI0616466B1 (pt) | 2005-10-07 | 2021-01-26 | Johnson & Johnson Research Pty Limited | composição de enzimas de ácido nucleico multicomponentes (mnazima), métodos para detectar a presença de pelo menos um facilitador de combinação, um alvo e uma variante de sequência de ácidos nucléicos, métodos para fabricar uma pluraridade de mnazima, testar sequências de núcleo catalítico parcial e identificar suas posições, bem como uso de pelo menos um oligonucleotídeo |
| WO2007056312A2 (en) * | 2005-11-07 | 2007-05-18 | Clontech Laboratories, Inc. | Universal reporter tag for nucleozyme assays |
| AU2006323930B2 (en) * | 2005-12-07 | 2012-06-21 | Janssen Sciences Ireland Uc | Methods, plasmid vectors and primers for assessing HIV viral fitness |
| WO2008001376A2 (en) * | 2006-06-28 | 2008-01-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Detection of analytes in a medium |
| DE102006035600B3 (de) * | 2006-07-27 | 2007-11-08 | Epigenomics Ag | Verfahren zum Nachweis eines Methylierungsmusters |
| EP1882746A3 (en) * | 2006-07-27 | 2008-03-19 | Epigenomics AG | Method for detecting a methylation pattern |
| KR20090098960A (ko) | 2006-10-06 | 2009-09-18 | 존슨 앤드 존슨 리서치 피티와이 리미티드 | 분자 스위치 및 이의 이용 방법 |
| US9938641B2 (en) * | 2006-12-18 | 2018-04-10 | Fluidigm Corporation | Selection of aptamers based on geometry |
| WO2008122084A1 (en) | 2007-04-05 | 2008-10-16 | Johnson & Johnson Research Pty Limited | Nucleic acid enzymes and complexes and methods for their use |
| EP2071035A1 (en) * | 2007-12-13 | 2009-06-17 | Epigenomics AG | Facilitator and method for amplification |
| WO2010147848A2 (en) | 2009-06-15 | 2010-12-23 | Rd Biosciences, Inc. | Kits and methods for selective amplification and detection of nucleic acid targets |
| CN101907573B (zh) * | 2010-08-17 | 2012-08-22 | 复旦大学 | 一种高灵敏度的集成cmos光学生物芯片 |
| WO2012034130A2 (en) | 2010-09-10 | 2012-03-15 | Qiagen | Methods and compositions for nucleic acid detection |
| JP6088487B2 (ja) | 2011-04-15 | 2017-03-01 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | 走査リアルタイムマイクロ流体熱サイクラーと同期熱サイクリング及び走査光学検出の方法 |
| CN104040238B (zh) | 2011-11-04 | 2017-06-27 | 汉迪拉布公司 | 多核苷酸样品制备装置 |
| AU2013202354A1 (en) * | 2012-06-18 | 2014-01-16 | Speedx Pty Ltd | Target detection and signal amplification |
| CN103013953B (zh) * | 2012-10-19 | 2014-09-17 | 中国科学院成都生物研究所 | 一种剪切dna的dna酶 |
| CN105518156A (zh) * | 2013-09-05 | 2016-04-20 | 日本电气方案创新株式会社 | 用于制备样品的方法和用于分析靶标的方法 |
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| US5112734A (en) * | 1989-05-26 | 1992-05-12 | Gene-Trak Systems | Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna |
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-
1999
- 1999-02-22 CA CA002321948A patent/CA2321948A1/en not_active Abandoned
- 1999-02-22 IL IL13812699A patent/IL138126A0/xx not_active IP Right Cessation
- 1999-02-22 EP EP99914694A patent/EP1062367B1/en not_active Expired - Lifetime
- 1999-02-22 IL IL16418299A patent/IL164182A0/xx unknown
- 1999-02-22 BR BR9908567-4A patent/BR9908567A/pt not_active Application Discontinuation
- 1999-02-22 CN CNB998111147A patent/CN1167811C/zh not_active Expired - Fee Related
- 1999-02-22 AU AU33409/99A patent/AU768627B2/en not_active Ceased
- 1999-02-22 US US09/253,955 patent/US6140055A/en not_active Expired - Lifetime
- 1999-02-22 JP JP2000534677A patent/JP4318856B2/ja not_active Expired - Fee Related
- 1999-02-22 DE DE69939896T patent/DE69939896D1/de not_active Expired - Fee Related
- 1999-02-22 AT AT99914694T patent/ATE414169T1/de not_active IP Right Cessation
- 1999-02-22 KR KR1020007009783A patent/KR100748863B1/ko not_active Expired - Fee Related
- 1999-02-22 WO PCT/IB1999/000754 patent/WO1999045146A1/en not_active Ceased
- 1999-03-04 ZA ZA9901772A patent/ZA991772B/xx unknown
-
2000
- 2000-08-11 US US09/637,405 patent/US6201113B1/en not_active Expired - Lifetime
- 2000-12-21 US US09/746,985 patent/US6365724B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69939896D1 (de) | 2008-12-24 |
| KR100748863B1 (ko) | 2007-08-13 |
| IL164182A0 (en) | 2005-12-18 |
| ATE414169T1 (de) | 2008-11-15 |
| CN1319142A (zh) | 2001-10-24 |
| JP4318856B2 (ja) | 2009-08-26 |
| EP1062367A4 (en) | 2003-07-30 |
| AU768627B2 (en) | 2003-12-18 |
| US20010001063A1 (en) | 2001-05-10 |
| JP2002505117A (ja) | 2002-02-19 |
| AU3340999A (en) | 1999-09-20 |
| CN1167811C (zh) | 2004-09-22 |
| EP1062367A1 (en) | 2000-12-27 |
| ZA991772B (en) | 2000-10-12 |
| BR9908567A (pt) | 2000-12-12 |
| US6140055A (en) | 2000-10-31 |
| EP1062367B1 (en) | 2008-11-12 |
| US6365724B2 (en) | 2002-04-02 |
| IL138126A0 (en) | 2001-10-31 |
| KR20010041591A (ko) | 2001-05-25 |
| WO1999045146A1 (en) | 1999-09-10 |
| US6201113B1 (en) | 2001-03-13 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |