JP3847559B2 - 独立スライド加熱器を有する自動化分子病理学装置 - Google Patents
独立スライド加熱器を有する自動化分子病理学装置 Download PDFInfo
- Publication number
- JP3847559B2 JP3847559B2 JP2000533730A JP2000533730A JP3847559B2 JP 3847559 B2 JP3847559 B2 JP 3847559B2 JP 2000533730 A JP2000533730 A JP 2000533730A JP 2000533730 A JP2000533730 A JP 2000533730A JP 3847559 B2 JP3847559 B2 JP 3847559B2
- Authority
- JP
- Japan
- Prior art keywords
- slide
- temperature
- heater
- heating
- heaters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Microscoopes, Condenser (AREA)
- Laminated Bodies (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7619898P | 1998-02-27 | 1998-02-27 | |
| US60/076,198 | 1998-02-27 | ||
| PCT/US1999/004181 WO1999044030A1 (en) | 1998-02-27 | 1999-02-26 | Automated molecular pathology apparatus having independent slide heaters |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006190677A Division JP4091960B2 (ja) | 1998-02-27 | 2006-07-11 | 顕微鏡スライド加熱システム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002505089A JP2002505089A (ja) | 2002-02-19 |
| JP3847559B2 true JP3847559B2 (ja) | 2006-11-22 |
Family
ID=22130540
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000533730A Expired - Lifetime JP3847559B2 (ja) | 1998-02-27 | 1999-02-26 | 独立スライド加熱器を有する自動化分子病理学装置 |
| JP2000533222A Pending JP2002504694A (ja) | 1998-02-27 | 1999-02-26 | 試薬を吸引し分配する(aspiratinganddispensing)システムと方法 |
| JP2006190677A Expired - Lifetime JP4091960B2 (ja) | 1998-02-27 | 2006-07-11 | 顕微鏡スライド加熱システム |
| JP2009120016A Expired - Lifetime JP4505538B2 (ja) | 1998-02-27 | 2009-05-18 | 試薬を吸引し分配するシステムと方法 |
| JP2009282843A Expired - Lifetime JP4505547B2 (ja) | 1998-02-27 | 2009-12-14 | 試薬を吸引し分配するシステムと方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000533222A Pending JP2002504694A (ja) | 1998-02-27 | 1999-02-26 | 試薬を吸引し分配する(aspiratinganddispensing)システムと方法 |
| JP2006190677A Expired - Lifetime JP4091960B2 (ja) | 1998-02-27 | 2006-07-11 | 顕微鏡スライド加熱システム |
| JP2009120016A Expired - Lifetime JP4505538B2 (ja) | 1998-02-27 | 2009-05-18 | 試薬を吸引し分配するシステムと方法 |
| JP2009282843A Expired - Lifetime JP4505547B2 (ja) | 1998-02-27 | 2009-12-14 | 試薬を吸引し分配するシステムと方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6296809B1 (https=) |
| EP (3) | EP1056541B1 (https=) |
| JP (5) | JP3847559B2 (https=) |
| CN (1) | CN100403008C (https=) |
| AT (1) | ATE489613T1 (https=) |
| AU (3) | AU2883499A (https=) |
| CA (2) | CA2321836C (https=) |
| DE (1) | DE69942975D1 (https=) |
| ES (1) | ES2354598T3 (https=) |
| WO (2) | WO1999044030A1 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150095832A (ko) * | 2012-12-26 | 2015-08-21 | 벤타나 메디컬 시스템즈, 인코포레이티드 | 검체 프로세싱 시스템들 및 슬라이드들을 균일하게 가열하는 방법들 |
| JP2020510196A (ja) * | 2017-03-16 | 2020-04-02 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. | 診断分析装置におけるインキュベーションシステムの温度制御のためのシステム及び方法 |
| US10746752B2 (en) | 2009-11-13 | 2020-08-18 | Ventana Medical Systems, Inc. | Opposables and automated specimen processing systems with opposables |
Families Citing this family (248)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6180061B1 (en) | 1992-05-11 | 2001-01-30 | Cytologix Corporation | Moving platform slide stainer with heating elements |
| US20040191128A1 (en) * | 1992-05-11 | 2004-09-30 | Cytologix Corporation | Slide stainer with heating |
| US6735531B2 (en) | 1996-10-07 | 2004-05-11 | Lab Vision Corporation | Method and apparatus for automatic tissue staining |
| JP3750772B2 (ja) * | 1998-01-27 | 2006-03-01 | 富士写真フイルム株式会社 | 生化学分析装置 |
| GB9803684D0 (en) * | 1998-02-24 | 1998-04-15 | Genevac Ltd | Method and apparatus for controlling temperature during evaporation of samples |
| US7396508B1 (en) | 2000-07-12 | 2008-07-08 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US6582962B1 (en) * | 1998-02-27 | 2003-06-24 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US6183693B1 (en) * | 1998-02-27 | 2001-02-06 | Cytologix Corporation | Random access slide stainer with independent slide heating regulation |
| US7188001B2 (en) * | 1998-03-23 | 2007-03-06 | Cepheid | System and method for temperature control |
| US6495106B1 (en) * | 1998-03-24 | 2002-12-17 | Biogenex Laboratories | Automated staining apparatus |
| US6620620B1 (en) * | 1998-04-27 | 2003-09-16 | Era Systems, Inc. | Micro liquid evaporator |
| US7550298B2 (en) * | 1998-09-03 | 2009-06-23 | Ventana Medical Systems, Inc. | Automated immunohistochemical and in situ hybridization assay formulations |
| US6855552B2 (en) * | 1998-09-03 | 2005-02-15 | Ventana Medical Systems | Automated immunohistochemical and in situ hybridization assay formulations |
| US6649128B1 (en) * | 1998-09-23 | 2003-11-18 | Randox Laboratories Ltd | Assay device processing instrument |
| US6544798B1 (en) * | 1999-02-26 | 2003-04-08 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
| US6706519B1 (en) * | 1999-06-22 | 2004-03-16 | Tecan Trading Ag | Devices and methods for the performance of miniaturized in vitro amplification assays |
| US8298485B2 (en) * | 1999-07-08 | 2012-10-30 | Lee H. Angros | In situ heat induced antigen recovery and staining apparatus and method |
| US7897106B2 (en) | 1999-07-08 | 2011-03-01 | Lee Angros | Situ heat induced antigen recovery and staining apparatus and method |
| US6534008B1 (en) * | 1999-07-08 | 2003-03-18 | Lee Angros | In situ heat induced antigen recovery and staining apparatus and method |
| US7951612B2 (en) * | 1999-07-08 | 2011-05-31 | Lee H. Angros | In situ heat induced antigen recovery and staining apparatus and method |
| EP1135680A4 (en) * | 1999-09-24 | 2004-12-15 | Ventana Med Syst Inc | HIGH-PERFORMANCE SYSTEM FOR EVALUATING THE CLINICAL BENEFIT OF TARGET MOLECULAR MOLECULES IN TISSUE SAMPLES |
| US6403931B1 (en) | 1999-10-07 | 2002-06-11 | Ventana Medical Systems, Inc. | Slide heater calibrator and temperature converter apparatus and method |
| DE10006084B4 (de) * | 2000-02-11 | 2009-01-02 | Leica Biosystems Nussloch Gmbh | Färbeautomat mit einer Heizstation |
| US6824738B1 (en) * | 2000-04-14 | 2004-11-30 | Discovery Partners International, Inc. | System and method for treatment of samples on solid supports |
| DE10041227B4 (de) * | 2000-08-22 | 2011-12-29 | Leica Biosystems Nussloch Gmbh | Vorrichtung zur Behandlung von Objekten |
| US6656685B2 (en) * | 2001-01-29 | 2003-12-02 | Ventana Medical Systems, Inc. | Hybridization buffers using low molecular weight dextran sulfate and methods for their use |
| GB0117706D0 (en) * | 2001-02-16 | 2001-09-12 | Aventis Pharm Prod Inc | Automated semi-solid matrix assay and liquid handler apparatus for the same |
| US7888060B2 (en) * | 2001-03-30 | 2011-02-15 | Nanoprobes, Inc. | Method for detecting a target using enzyme directed deposition of elemental metal |
| US7691598B2 (en) * | 2001-03-30 | 2010-04-06 | Nanoprobes, Inc. | Method for detecting a target molecule by metal deposition |
| US6662136B2 (en) * | 2001-04-10 | 2003-12-09 | International Business Machines Corporation | Digital temperature sensor (DTS) system to monitor temperature in a memory subsystem |
| AU2002305300B2 (en) * | 2001-04-30 | 2006-06-01 | Ventana Medical Systems, Inc. | Reagents and methods for automated in situ or microarray hybridization |
| US7425306B1 (en) | 2001-09-11 | 2008-09-16 | Ventana Medical Systems, Inc. | Slide heater |
| US7270785B1 (en) | 2001-11-02 | 2007-09-18 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having fixed slide platforms |
| US6936474B2 (en) * | 2001-11-05 | 2005-08-30 | Industrial Technology Research Institute | Method and apparatus for manufacturing biochip |
| WO2003042788A2 (en) * | 2001-11-13 | 2003-05-22 | Chromavision Medical Systems, Inc. | A system for tracking biological samples |
| US20040033163A1 (en) * | 2001-11-26 | 2004-02-19 | Lab Vision Corporation | Automated tissue staining system and reagent container |
| US6998270B2 (en) | 2001-11-26 | 2006-02-14 | Lab Vision Corporation | Automated tissue staining system and reagent container |
| US6889468B2 (en) * | 2001-12-28 | 2005-05-10 | 3M Innovative Properties Company | Modular systems and methods for using sample processing devices |
| US7468161B2 (en) | 2002-04-15 | 2008-12-23 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
| US11249095B2 (en) | 2002-04-15 | 2022-02-15 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
| WO2003089140A1 (en) | 2002-04-15 | 2003-10-30 | Ventana Medical Systems, Inc. | Automated high volume slide staining system |
| EP1499872B1 (en) * | 2002-04-26 | 2015-11-18 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having fixed slide platforms |
| US6833536B2 (en) * | 2002-05-22 | 2004-12-21 | Applera Corporation | Non-contact radiant heating and temperature sensing device for a chemical reaction chamber |
| WO2003099222A2 (en) * | 2002-05-23 | 2003-12-04 | Invitrogen Corporation | Pseudo-tissues and uses thereof |
| WO2004008106A2 (en) * | 2002-07-16 | 2004-01-22 | Ventana Medical Systems, Inc. | Tray for automated histochemical processing |
| KR20040023999A (ko) * | 2002-09-12 | 2004-03-20 | 엘지전자 주식회사 | 의류건조기의 모터축 구조 |
| US7648678B2 (en) | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
| US7584019B2 (en) | 2003-12-15 | 2009-09-01 | Dako Denmark A/S | Systems and methods for the automated pre-treatment and processing of biological samples |
| US7875245B2 (en) * | 2003-05-14 | 2011-01-25 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
| US7850912B2 (en) | 2003-05-14 | 2010-12-14 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
| US20060073074A1 (en) * | 2004-10-06 | 2006-04-06 | Lars Winther | Enhanced sample processing system and methods of biological slide processing |
| CA2526126C (en) * | 2003-05-19 | 2012-05-15 | Ventana Medical Systems, Inc. | Electrophoretic in situ tissue staining |
| WO2004111610A2 (en) | 2003-06-12 | 2004-12-23 | Accupath Diagnostic Laboratories, Inc. | Method and system for the analysis of high density cells samples |
| US7642064B2 (en) | 2003-06-24 | 2010-01-05 | Ventana Medical Systems, Inc. | Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest |
| US7501283B2 (en) | 2003-08-11 | 2009-03-10 | Sakura Finetek U.S.A., Inc. | Fluid dispensing apparatus |
| US9518899B2 (en) | 2003-08-11 | 2016-12-13 | Sakura Finetek U.S.A., Inc. | Automated reagent dispensing system and method of operation |
| US7744817B2 (en) | 2003-08-11 | 2010-06-29 | Sakura Finetek U.S.A., Inc. | Manifold assembly |
| US7767152B2 (en) | 2003-08-11 | 2010-08-03 | Sakura Finetek U.S.A., Inc. | Reagent container and slide reaction retaining tray, and method of operation |
| US7273591B2 (en) | 2003-08-12 | 2007-09-25 | Idexx Laboratories, Inc. | Slide cartridge and reagent test slides for use with a chemical analyzer, and chemical analyzer for same |
| AU2004271210A1 (en) * | 2003-09-09 | 2005-03-17 | Biogenex Laboratories | Sample processing system |
| US7588733B2 (en) | 2003-12-04 | 2009-09-15 | Idexx Laboratories, Inc. | Retaining clip for reagent test slides |
| US8012693B2 (en) * | 2003-12-16 | 2011-09-06 | 3M Innovative Properties Company | Analysis of chemically crosslinked cellular samples |
| US8026106B1 (en) | 2003-12-18 | 2011-09-27 | Ventana Medical Systems, Inc. | Removal of mercuric chloride crystals from fixed tissues |
| WO2005064309A1 (en) | 2003-12-23 | 2005-07-14 | Ventana Medical Systems, Inc. | Method and apparatus for efficient thin film fluid |
| JP2007526479A (ja) * | 2004-03-02 | 2007-09-13 | ダコ デンマーク アクティーゼルスカブ | 生物学的染色装置のための試薬送達システム、分配デバイスおよび容器 |
| ES2315877T3 (es) | 2004-06-18 | 2009-04-01 | Biolipox Ab | Indoles utiles en el tratamiento de inflamaciones. |
| WO2006004739A2 (en) * | 2004-06-29 | 2006-01-12 | Dako Denmark A/S | Method of pre-treatment and staining of and support device for a biological sample |
| US7867443B2 (en) * | 2004-07-23 | 2011-01-11 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
| WO2006012498A1 (en) * | 2004-07-23 | 2006-02-02 | Ventana Medical Systems, Inc. | Method and apparatus for applying fluids to a biological sample |
| US7514041B2 (en) * | 2004-07-28 | 2009-04-07 | N-Solv Corporation | Method and apparatus for testing heavy oil production processes |
| CN101142185A (zh) | 2005-01-19 | 2008-03-12 | 比奥里波克斯公司 | 用于炎症治疗的吲哚 |
| GB0501590D0 (en) * | 2005-01-25 | 2005-03-02 | Ceres Power Ltd | Processing of enhanced performance LSCF fuel cell cathode microstructure and a fuel cell cathode |
| US8034610B2 (en) * | 2005-04-21 | 2011-10-11 | Celerus Diagnostics, Inc. | Parallel processing fluidic method and apparatus for automated rapid immunohistochemistry |
| DE102005020426B4 (de) * | 2005-04-29 | 2017-05-04 | Leica Biosystems Nussloch Gmbh | Eindeckautomat |
| AU2006249956A1 (en) | 2005-05-24 | 2006-11-30 | Angros, Lee H | In situ heat induced antigen recovery and staining apparatus and method |
| CN100406874C (zh) * | 2005-06-20 | 2008-07-30 | 北京源德生物医学工程有限公司 | 半自动微孔板单光子计数仪的门组件 |
| CA2613203C (en) * | 2005-06-28 | 2013-08-13 | The Board Of Regents Of The University Of Oklahoma | Methods for growing and harvesting carbon nanotubes |
| US7763210B2 (en) | 2005-07-05 | 2010-07-27 | 3M Innovative Properties Company | Compliant microfluidic sample processing disks |
| US7754474B2 (en) | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
| US7323660B2 (en) | 2005-07-05 | 2008-01-29 | 3M Innovative Properties Company | Modular sample processing apparatus kits and modules |
| GB0521851D0 (en) * | 2005-10-26 | 2005-12-07 | Genial Genetic Solutions Ltd | Biological apparatus |
| US9551635B2 (en) | 2006-03-09 | 2017-01-24 | Biogenex Laboratories Inc. | Sample processing system |
| US8459509B2 (en) | 2006-05-25 | 2013-06-11 | Sakura Finetek U.S.A., Inc. | Fluid dispensing apparatus |
| CA2549614C (en) * | 2006-06-07 | 2014-11-25 | N-Solv Corporation | Methods and apparatuses for sagd hydrocarbon production |
| CA2552482C (en) * | 2006-07-19 | 2015-02-24 | N-Solv Corporation | Methods and apparatuses for enhanced in situ hydrocarbon production |
| EP2069800B1 (en) * | 2006-09-22 | 2012-03-28 | Fujifilm Corporation | Clinical analysis apparatus |
| DK2444807T3 (da) | 2006-11-01 | 2014-08-11 | Ventana Med Syst Inc | Mono- og dinitropyrazolhaptenkonjugater |
| WO2008140742A1 (en) | 2007-05-08 | 2008-11-20 | Idexx Laboratories, Inc. | Chemical analyzer |
| EP2167963B1 (en) | 2007-05-23 | 2019-04-17 | Ventana Medical Systems, Inc. | Polymeric carriers for immunohistochemistry and in situ hybridization |
| US8883509B2 (en) * | 2007-07-10 | 2014-11-11 | Ventana Medical Systems, Inc. | Apparatus and method for biological sample processing |
| US8440425B2 (en) * | 2007-12-18 | 2013-05-14 | Abbott Laboratories | Method of preparing a biological specimen slide |
| WO2009106081A1 (en) | 2008-02-29 | 2009-09-03 | Dako Denmark A/S | Systems and methods for tracking and providing workflow information |
| US9802022B2 (en) * | 2008-03-06 | 2017-10-31 | Resmed Limited | Humidification of respiratory gases |
| WO2009149013A2 (en) | 2008-06-05 | 2009-12-10 | Ventana Medical Systems, Inc. | Compositions comprising nanomaterials and method for using such compositions for histochemical processes |
| EP2334827B1 (en) | 2008-08-22 | 2015-03-11 | Ventana Medical Systems, Inc. | Method for chromogenic detection of two or more target molecules in a single sample |
| WO2010025425A1 (en) | 2008-08-29 | 2010-03-04 | Angros Lee H | Multiplexed microscope slide staining apparatus |
| US8501115B2 (en) * | 2008-10-24 | 2013-08-06 | Statspin, Inc. | Modular system for performing laboratory protocols and associated methods |
| CA2742473C (en) | 2008-11-12 | 2015-02-24 | Ventana Medical Systems, Inc. | Methods and apparatuses for heating slides carrying specimens |
| WO2010138908A1 (en) | 2009-05-29 | 2010-12-02 | Ventana Medical Systems, Inc. | Igfir gene copy number as a prognostic marker in a non-small cell lung cancer |
| CA2763321C (en) | 2009-05-29 | 2018-10-16 | Ventana Medical Systems, Inc. | Methods of scoring gene copy number in a biological sample using in situ hybridization |
| DE102010010975B4 (de) | 2009-09-14 | 2012-05-31 | Dcs Innovative Diagnostik-Systeme Dr. Christian Sartori Gmbh & Co. Kg | Objektträgerhalter |
| JP5611363B2 (ja) * | 2009-11-13 | 2014-10-22 | ベンタナ メディカル システムズ, インコーポレイテッド | 調整可能な体積を収容する薄膜処理装置 |
| USD638550S1 (en) | 2009-11-13 | 2011-05-24 | 3M Innovative Properties Company | Sample processing disk cover |
| USD667561S1 (en) | 2009-11-13 | 2012-09-18 | 3M Innovative Properties Company | Sample processing disk cover |
| US9498791B2 (en) | 2009-11-13 | 2016-11-22 | Ventana Medical Systems, Inc. | Opposables and automated specimen processing systems with opposables |
| USD638951S1 (en) | 2009-11-13 | 2011-05-31 | 3M Innovative Properties Company | Sample processing disk cover |
| WO2014102160A1 (en) * | 2012-12-26 | 2014-07-03 | Ventana Medical Systems, Inc. | Automated specimen processing systems and methods of using the same |
| US8834792B2 (en) | 2009-11-13 | 2014-09-16 | 3M Innovative Properties Company | Systems for processing sample processing devices |
| JP5683501B2 (ja) | 2010-02-05 | 2015-03-11 | 株式会社ニチレイバイオサイエンス | 免疫組織化学染色用前処理液及びその濃縮液 |
| EP2539355B1 (en) | 2010-02-26 | 2016-10-05 | Ventana Medical Systems, Inc. | In-situ hybridization with polytag probes |
| WO2011106495A1 (en) | 2010-02-26 | 2011-09-01 | Ventana Medical Systems, Inc. | Cytogenic analysis of metaphase chromosomes |
| WO2011109769A1 (en) | 2010-03-04 | 2011-09-09 | Ventana Medical Systems, Inc. | Processing system for processing specimens using acoustic energy |
| US10539487B2 (en) | 2010-03-04 | 2020-01-21 | Ventana Medical Systems, Inc. | Systems and methods for monitoring tissue sample processing |
| US10126216B2 (en) | 2011-02-17 | 2018-11-13 | Ventana Medical Systems, Inc. | Method for tissue sample fixation |
| AU2011248607B2 (en) | 2010-04-27 | 2015-02-05 | Ventana Medical Systems, Inc. | Antibody-nanoparticle conjugates and methods for making and using such conjugates |
| EP2564206A4 (en) | 2010-04-29 | 2016-09-07 | Leica Biosystems Richmond Inc | ANALYSIS SYSTEM FOR CARRYING OUT LABORATORY PROTOCOLS AND RELATED METHODS |
| WO2011149943A1 (en) | 2010-05-24 | 2011-12-01 | Ventana Midical Systems, Inc. | Method for differentiation of non-small cellung carcinoma |
| EP2752668A3 (en) * | 2010-07-23 | 2014-10-15 | Beckman Coulter, Inc. | System Or Method Of Including Analytical Units |
| JP5393610B2 (ja) * | 2010-07-28 | 2014-01-22 | 株式会社日立ハイテクノロジーズ | 核酸分析装置 |
| WO2012048154A1 (en) | 2010-10-06 | 2012-04-12 | Biocare Medical, Llc | Methods and systems for efficient processing of biological samples |
| SG190892A1 (en) | 2010-12-30 | 2013-07-31 | Ventana Med Syst Inc | Enhanced deposition of chromogens utilizing pyrimidine analogs |
| BR112013017366A2 (pt) | 2011-01-10 | 2016-10-04 | Ventana Med Syst Inc | processo automatizado para coloração de uma amostra biológica compreendendo células e sistema para coloração de uma amostra biológica montado em um substrato |
| US8752732B2 (en) | 2011-02-01 | 2014-06-17 | Sakura Finetek U.S.A., Inc. | Fluid dispensing system |
| US9945763B1 (en) | 2011-02-18 | 2018-04-17 | Biocare Medical, Llc | Methods and systems for immunohistochemistry heat retrieval of biological samples |
| CN107255584B (zh) | 2011-02-28 | 2021-04-13 | 安捷伦科技有限公司 | 用于预处理包埋的生物样本的不混溶两相系统 |
| US9562259B2 (en) | 2011-03-14 | 2017-02-07 | Ventana Medical Systems, Inc. | Method of analyzing chromosomal inversions |
| USD672467S1 (en) | 2011-05-18 | 2012-12-11 | 3M Innovative Properties Company | Rotatable sample processing disk |
| US9168523B2 (en) | 2011-05-18 | 2015-10-27 | 3M Innovative Properties Company | Systems and methods for detecting the presence of a selected volume of material in a sample processing device |
| AU2012255144B2 (en) | 2011-05-18 | 2015-01-29 | Diasorin Italia S.P.A. | Systems and methods for volumetric metering on a sample processing device |
| CN103501908B (zh) | 2011-05-18 | 2016-03-16 | 3M创新有限公司 | 用于样品处理装置上阀调的系统和方法 |
| US8580568B2 (en) | 2011-09-21 | 2013-11-12 | Sakura Finetek U.S.A., Inc. | Traceability for automated staining system |
| US8932543B2 (en) | 2011-09-21 | 2015-01-13 | Sakura Finetek U.S.A., Inc. | Automated staining system and reaction chamber |
| WO2013079606A1 (en) | 2011-12-01 | 2013-06-06 | Ventana Medical Systems, Inc. | Automated dual stain of mirna and protein targets |
| US20130171642A1 (en) | 2011-12-30 | 2013-07-04 | Ventana Medical Systems, Inc. | Automated analysis of circulating tumor cells |
| ES2827785T3 (es) | 2012-01-26 | 2021-05-24 | Leica Biosystems Richmond Inc | Kit para tinción con hematoxilina y eosina |
| EP2807272A1 (en) | 2012-01-27 | 2014-12-03 | Ventana Medical Systems, Inc. | Devices and methods for detecting bio-analytes using optically decipherable patterns |
| ES2779626T3 (es) | 2012-02-01 | 2020-08-18 | Ventana Med Syst Inc | Sistema para detectar genes en muestras de tejido |
| US9909962B2 (en) | 2012-03-09 | 2018-03-06 | Leica Biosystems Richmond, Inc. | Device and method for controlling the temperature in a moving fluid in a laboratory sample processing system |
| US9023615B2 (en) | 2012-03-19 | 2015-05-05 | Ventana Medical Systems, Inc. | Gram staining method with improved decolorization of the crystal violet-iodine complex from gram negative bacteria |
| BR112014026735B1 (pt) * | 2012-04-27 | 2021-11-23 | Cepheid | Aparelho de processamento de amostra biológica, e, método para operar um aparelho de processamento de amostra |
| JP6253657B2 (ja) | 2012-10-08 | 2017-12-27 | ヴェンタナ メディカル システムズ, インク. | 有色素サンプルを明確化するための方法、キット、及びシステム |
| CN104769410B (zh) | 2012-11-06 | 2018-07-27 | 拜奥-多特公司 | 用于核型分析的细胞样本的受控印刷 |
| WO2014079802A2 (en) | 2012-11-20 | 2014-05-30 | Ventana Medical Systems, Inc. | Laser ablation inductively-coupled plasma mass spectral tissue diagnostics |
| EP2925450B1 (en) | 2012-12-03 | 2017-09-13 | Leica Biosystems Melbourne Pty Ltd | Thermal module for a sample processing assembly |
| US11274998B2 (en) | 2012-12-26 | 2022-03-15 | Ventana Medical Systems, Inc. | Specimen processing systems and methods for holding slides |
| US9989448B2 (en) | 2012-12-26 | 2018-06-05 | Ventana Medical Systems, Inc. | Specimen processing systems and methods for holding slides |
| CN103149070B (zh) * | 2013-03-11 | 2014-10-08 | 黄石市第一医院 | 一种自动染片机 |
| USD728120S1 (en) | 2013-03-15 | 2015-04-28 | Ventana Medical Systems, Inc. | Arcuate member for moving liquids along a microscope slide |
| US10429279B2 (en) * | 2013-07-28 | 2019-10-01 | Xmd, Llc | Devices and cartridges for extracting bio-sample regions and molecules of interest |
| JP6302066B2 (ja) | 2013-12-13 | 2018-03-28 | ベンタナ メディカル システムズ, インコーポレイテッド | 顕微鏡スライドを熱処理する自動化された処理システムおよび方法 |
| CN111089980B (zh) * | 2013-12-13 | 2023-08-15 | 文塔纳医疗系统公司 | 生物样本的自动化组织学处理及相关的技术 |
| CN105980828B (zh) | 2013-12-13 | 2021-12-17 | 文塔纳医疗系统公司 | 用于生物标本组织处理的染色试剂和其它液体及关联技术 |
| WO2015086485A1 (en) * | 2013-12-13 | 2015-06-18 | Ventana Medical Systems, Inc. | Thermal management in the context of automated histological processing of biological specimens and associated technology |
| US9797916B2 (en) | 2014-01-10 | 2017-10-24 | Idexx Laboratories, Inc. | Chemical analyzer |
| CA2940439C (en) | 2014-02-24 | 2024-03-19 | Ventana Medical Systems, Inc. | Quinone methide analog signal amplification |
| EP3110966A1 (en) | 2014-02-24 | 2017-01-04 | Ventana Medical Systems, Inc. | Automated rna detection using labeled 2'-o-methyl rna oligonucleotide probes and signal amplification systems |
| EP3152577B1 (en) | 2014-06-06 | 2018-07-18 | Ventana Medical Systems, Inc. | Significance of intratumoral her2 heterogeneity in breast cancer and uses therefor |
| EP3160648B1 (en) | 2014-06-30 | 2024-04-03 | Ventana Medical Systems, Inc. | Specimen processing systems, pipette assemblies and methods for preparing reagents |
| CA2957783C (en) | 2014-10-02 | 2023-02-28 | Ventana Medical Systems, Inc. | Polymers and conjugates comprising the same |
| CN107111874B (zh) | 2014-12-30 | 2022-04-08 | 文塔纳医疗系统公司 | 用于共表达分析的系统和方法 |
| AU2016212229B2 (en) | 2015-01-27 | 2019-06-06 | Ventana Medical Systems, Inc. | Methods for tissue sample fixation using an extended soak in aldehyde-based fixative solutions |
| EP3251087B1 (en) | 2015-01-29 | 2018-11-28 | Ventana Medical Systems, Inc. | Dot detection, color classification of dots and counting of color classified dots |
| WO2016120441A2 (en) | 2015-01-30 | 2016-08-04 | Ventana Medical Systems, Inc. | Quality metrics for automatic evaluation of dual ish images |
| WO2016120442A1 (en) | 2015-01-30 | 2016-08-04 | Ventana Medical Systems, Inc. | Foreground segmentation and nucleus ranking for scoring dual ish images |
| WO2016146616A1 (en) | 2015-03-16 | 2016-09-22 | Ventana Medical Systems, Inc. | Control slides for immunohistochemistry generated from three-dimensional cell line cultures |
| AU2016248882B2 (en) * | 2015-04-13 | 2020-04-30 | Ventana Medical Systems, Inc. | Thermochemical-based antibody inactivation methods and systems |
| CA2984701C (en) | 2015-05-10 | 2023-09-26 | Ventana Medical Systems, Inc. | Compositions and methods for simultaneous inactivation of alkaline phosphatase and peroxidase enzymes during automated multiplex tissue staining assays |
| WO2016189065A1 (en) | 2015-05-26 | 2016-12-01 | Ventana Medical Systems, Inc. | Method and system for assessing stain quality for in-situ hybridization and immunohistochemistry |
| AU2016316846B2 (en) | 2015-08-28 | 2021-07-08 | Ventana Medical Systems, Inc. | Protein proximity assay in formalin fixed paffafin embedded tissue using caged haptens |
| CN105400693B (zh) * | 2015-12-15 | 2017-06-06 | 上海海洋大学 | 平板等温核酸扩增芯片 |
| CN105400692B (zh) * | 2015-12-15 | 2017-06-27 | 上海海洋大学 | 等温核酸扩增装置及等温核酸扩增实验方法 |
| WO2017132276A1 (en) | 2016-01-26 | 2017-08-03 | Ventana Medical Systems, Inc. | Predictive diagnostic workflow for tumors usnig automated dissection, next generation sequencing, and automated slide stainers |
| WO2017155996A1 (en) | 2016-03-08 | 2017-09-14 | Ventana Medical Systems, Inc. | Multiplexed immunohistochemistry using recombinant antibodies with epitope tags |
| US11460383B2 (en) | 2016-06-16 | 2022-10-04 | Nanocytomics, LLC | Automated staining system |
| JP7128121B2 (ja) | 2016-06-28 | 2022-08-30 | ヴェンタナ メディカル システムズ, インク. | Ihc及びishアッセイにおけるシグナル増幅のためのクリックケミストリーの応用 |
| WO2018002015A1 (en) | 2016-06-28 | 2018-01-04 | Ventana Medical Systems, Inc. | New colors for chromogenic ihc and ish staining with multi-dye quinone methide and tyramide conjugates |
| DE112016007190T5 (de) * | 2016-08-30 | 2019-07-04 | Aiham Z. S. Qdaisat | Automatisiertes Objektträgerbetropfungssystem |
| EP3516397A1 (en) | 2016-09-23 | 2019-07-31 | Ventana Medical Systems, Inc. | Methods and systems for scoring extracellular matrix biomarkers in tumor samples |
| CN106370830A (zh) * | 2016-11-14 | 2017-02-01 | 漯河医学高等专科学校 | 一种具有单独滑片加热器的分子病理学装置 |
| EP3555634B1 (en) | 2016-12-16 | 2023-09-06 | Ventana Medical Systems, Inc. | Dispenser nozzle residue mitigation |
| EP3554556B1 (en) | 2016-12-19 | 2022-03-09 | Ventana Medical Systems, Inc. | Peptide nucleic acid conjugates |
| ES2869903T3 (es) | 2016-12-19 | 2021-10-26 | Ventana Med Syst Inc | Sistema pasivo accionado por gravedad para el tratamiento de un efluente en un sistema de diagnóstico |
| WO2018118786A1 (en) | 2016-12-19 | 2018-06-28 | Ventana Medical Systems, Inc. | Methods and systems for quantitative immunohistochemistry |
| JP7025430B2 (ja) | 2016-12-21 | 2022-02-24 | ヴェンタナ メディカル システムズ, インク. | 試薬送達のための方法、システム、及び固体組成物 |
| WO2018119295A1 (en) | 2016-12-22 | 2018-06-28 | Ventana Medical Systems, Inc. | Fully automated nucleic acid extraction method for tissue samples |
| JP6968177B2 (ja) | 2016-12-22 | 2021-11-17 | ベンタナ メディカル システムズ, インコーポレイテッド | 一次染色および免疫組織化学画像に基づくコンピュータ採点 |
| CN110192089A (zh) * | 2017-01-19 | 2019-08-30 | 安捷伦科技有限公司 | 多温光谱仪模块、系统及其使用方法 |
| CN110494891B (zh) | 2017-04-14 | 2023-11-28 | 文塔纳医疗系统公司 | 用于拼接的基于分块的局部配准以及全局放置 |
| EP3622266B1 (en) | 2017-05-10 | 2022-08-17 | Ventana Medical Systems, Inc. | Stabilized two-part hematoxylin solution utilizing ph adjustment, method for staining and kit |
| EP3631410B1 (en) | 2017-05-26 | 2024-08-28 | Ventana Medical Systems, Inc. | Non-contact, on-slide fluid mixing |
| CN110785654A (zh) | 2017-06-28 | 2020-02-11 | 文塔纳医疗系统公司 | 系统级校准 |
| EP3659110A1 (en) | 2017-07-24 | 2020-06-03 | Ventana Medical Systems, Inc. | Methods and systems for evaluation of immune cell infiltrate in tumor samples |
| JP7216707B2 (ja) | 2017-08-04 | 2023-02-01 | ベンタナ メディカル システムズ, インコーポレイテッド | 散乱補正を用いた色分離 |
| EP3662484B1 (en) | 2017-08-04 | 2024-01-03 | Ventana Medical Systems, Inc. | Automatic assay assessment and normalization for image processing |
| EP3714251B1 (en) | 2017-11-21 | 2024-04-03 | Ventana Medical Systems, Inc. | Contactless mixing using modulated air jets |
| WO2019110567A1 (en) | 2017-12-05 | 2019-06-13 | Ventana Medical Systems, Inc. | Method of computing tumor spatial and inter-marker heterogeneity |
| JP7197584B2 (ja) | 2017-12-06 | 2022-12-27 | ベンタナ メディカル システムズ, インコーポレイテッド | デジタル病理学分析結果の格納および読み出し方法 |
| EP3721373B1 (en) | 2017-12-07 | 2025-03-05 | Ventana Medical Systems, Inc. | Deep-learning systems and methods for joint cell and region classification in biological images |
| JP7727385B2 (ja) | 2017-12-18 | 2025-08-21 | ヴェンタナ メディカル システムズ, インク. | ペプチド核酸コンジュゲート |
| AU2018391801B2 (en) | 2017-12-24 | 2022-12-22 | Ventana Medical Systems, Inc. | Phenol-free acid-fast staining composition and use thereof |
| EP3729047A2 (en) | 2017-12-24 | 2020-10-28 | Ventana Medical Systems, Inc. | Eosin staining techniques |
| EP3729369A2 (en) | 2017-12-24 | 2020-10-28 | Ventana Medical Systems, Inc. | Computational pathology approach for retrospective analysis of tissue-based companion diagnostic driven clinical trial studies |
| JP2021510894A (ja) | 2018-01-11 | 2021-04-30 | ベンタナ メディカル システムズ, インコーポレイテッド | 曇り止めバーコード・リーダ |
| ES2965647T3 (es) | 2018-01-31 | 2024-04-16 | Ventana Med Syst Inc | Procedimientos y sistemas para la evaluación de infiltrado de células inmunitarias en cáncer colorrectal en estadio III |
| WO2019197509A1 (en) | 2018-04-13 | 2019-10-17 | Ventana Medical Systems, Inc. | Systems for cell shape estimation |
| CN112424825B (zh) | 2018-05-15 | 2025-01-07 | 文塔纳医疗系统公司 | 染色聚集体中信号的定量 |
| EP3797296B1 (en) | 2018-05-21 | 2024-09-04 | Genentech, Inc. | Her2 heterogeneity as a biomarker in cancer |
| WO2020016266A1 (en) | 2018-07-17 | 2020-01-23 | Ventana Medical Systems, Inc. | Materials and methods for detecting fusion proteins |
| US12020493B2 (en) | 2018-07-27 | 2024-06-25 | Ventana Medical Systems, Inc. | Systems for automated in situ hybridization analysis |
| CA3108986A1 (en) | 2018-08-09 | 2020-02-13 | Ventana Medical Systems, Inc. | Determination of parkinson's disease |
| WO2020053376A1 (en) | 2018-09-13 | 2020-03-19 | Ventana Medical Systems, Inc. | Histochemical and cytochemical methods for detecting ntrk fusion proteins |
| JP7455816B2 (ja) | 2018-09-20 | 2024-03-26 | ヴェンタナ メディカル システムズ, インク. | クマリン系架橋試薬 |
| CN112789684B (zh) | 2018-10-01 | 2025-05-09 | 文塔纳医疗系统公司 | 用于预测对pd-1轴导向疗法的应答的方法和系统 |
| JP7228688B2 (ja) | 2018-10-15 | 2023-02-24 | ベンタナ メディカル システムズ, インコーポレイテッド | 改善された核検出およびセグメンテーションを可能にする画像強化 |
| CN112868024B (zh) | 2018-10-15 | 2025-11-25 | 文塔纳医疗系统公司 | 用于细胞分类的系统和方法 |
| CN113348356A (zh) | 2018-11-20 | 2021-09-03 | 文塔纳医疗系统公司 | 用于针对形态学特征和生物标志物表达而制备和分析细胞样品的方法和系统 |
| WO2020161125A1 (en) | 2019-02-05 | 2020-08-13 | Ventana Medical Systems, Inc. | Methods and systems for evaluation of immune cell infiltrate in stage iv colorectal cancer |
| CN113785184B (zh) | 2019-05-14 | 2025-02-28 | 文塔纳医疗系统公司 | 包括生物学样品处理腔室的系统 |
| WO2021037875A1 (en) | 2019-08-28 | 2021-03-04 | Ventana Medical Systems, Inc. | Systems and methods for assessing specimen fixation duration and quality using vibrational spectroscopy |
| EP4022624B1 (en) | 2019-08-28 | 2026-03-11 | Ventana Medical Systems, Inc. | Assessing antigen retrieval and target retrieval progression quantitation with vibrational spectroscopy |
| EP4110823A1 (en) | 2020-02-26 | 2023-01-04 | A2 Biotherapeutics, Inc. | Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof |
| CN114207403B (zh) * | 2020-03-11 | 2022-11-22 | 贵州美鑫达医疗科技有限公司 | 用于自动组织处理和染色的装置和组件及其使用 |
| US20250130143A1 (en) * | 2020-03-11 | 2025-04-24 | Jin V. WU | Devices and components for automated tissue processing and staining and uses thereof |
| CN115244404B (zh) * | 2020-03-17 | 2025-12-09 | 株式会社日立高新技术 | 自动分析装置 |
| WO2021224293A1 (en) | 2020-05-07 | 2021-11-11 | Ventana Medical Systems, Inc. | Histochemical systems and methods for evaluating egfr and egfr ligand expression in tumor samples |
| CN115552214A (zh) | 2020-05-08 | 2022-12-30 | 文塔纳医疗系统公司 | 外消旋苏木精的半合成和用途 |
| JP2023526468A (ja) | 2020-05-20 | 2023-06-21 | ロシュ・ダイアグノスティクス・ヘマトロジー・インコーポレイテッド | スライド上にプリントされたバイオマーカーおよびロマノフスキー型染色サンプルを調製するための自動化プラットフォームの使用 |
| EP4158305B1 (en) * | 2020-05-27 | 2025-01-08 | Agilent Technologies, Inc. | Apparatus and method for processing biological samples |
| CN113804902B (zh) * | 2020-06-16 | 2025-09-09 | 深圳迈瑞生物医疗电子股份有限公司 | 样本分析仪故障自诊断的方法及样本分析仪 |
| CN115836207B (zh) | 2020-07-10 | 2026-04-24 | Idexx实验室公司 | 护理点医学诊断分析仪、以及用于对样品进行医学诊断分析的装置、系统和方法 |
| WO2022066512A1 (en) | 2020-09-22 | 2022-03-31 | Ventana Medical Systems, Inc. | Prediction of response to epidermal growth factor receptor-directed therapies using epiregulin and amphiregulin |
| CN112799444A (zh) * | 2020-12-27 | 2021-05-14 | 北京工业大学 | 一种基于51单片机的血液寄生虫检测温控加热仪 |
| WO2022152777A1 (en) | 2021-01-15 | 2022-07-21 | F. Hoffmann-La Roche Ag | Storage stable caged haptens |
| WO2022156920A1 (en) | 2021-01-25 | 2022-07-28 | Ventana Medical Systems, Inc. | Stained biological specimens including one or more biomarkers labeled with one or more detectable moieties |
| JP2024516380A (ja) | 2021-04-18 | 2024-04-15 | ヴェンタナ メディカル システムズ, インク. | 形態学的マーカー染色 |
| KR102736858B1 (ko) * | 2021-12-16 | 2024-12-04 | (주)레보스케치 | 회전형 다채널 형광스캐너 |
| WO2023147252A1 (en) | 2022-01-25 | 2023-08-03 | Ventana Medical Systems, Inc. | Materials and methods for bleaching melanin-pigmented tissues |
| JP2025513724A (ja) | 2022-03-31 | 2025-04-30 | ヴェンタナ メディカル システムズ, インク. | ミスマッチ修復が欠損した結腸直腸腫瘍におけるpd-1軸指向治療薬に対する応答を予測するための方法およびシステム |
| DE102022111890B3 (de) * | 2022-05-12 | 2023-03-16 | Dermagnostix GmbH | Verfahren zur Deparaffinierung von Formalin-fixiertem Paraffin-eingebettetem Gewebe |
| US20240044754A1 (en) * | 2022-06-03 | 2024-02-08 | 10X Genomics, Inc. | Methods, systems, and devices for sample interface |
| CN119343410A (zh) | 2022-06-09 | 2025-01-21 | 文塔纳医疗系统公司 | 希夫试剂的载玻片上合成 |
| WO2024137817A1 (en) | 2022-12-23 | 2024-06-27 | Ventana Medical Systems, Inc. | Materials and methods for evaluation of antigen presentation machinery components and uses thereof |
| EP4641164A1 (en) | 2022-12-23 | 2025-10-29 | Hitachi High-Tech Corporation | Slide glass cooling/heating device and slide glass cooling/heating method |
| WO2025014787A1 (en) | 2023-07-07 | 2025-01-16 | Ventana Medical Systems, Inc. | Brightfield triplex immunohistochemistry assay for evaluating the colocalization of the er, pr, and ki-67 biomarkers in cells |
| WO2025038339A1 (en) | 2023-08-16 | 2025-02-20 | Ventana Medical Systems, Inc. | Deep learning model to determine a fixation status of a morphologically stained biological specimen |
| WO2025166108A1 (en) | 2024-02-01 | 2025-08-07 | Ventana Medical Systems, Inc. | Methods of generating digitally stained images from unstained biological samples |
| WO2026072715A1 (en) | 2024-09-27 | 2026-04-02 | Ventana Medical Systems, Inc. | Compositions, kits, and methods for silver staining |
| CN119223966B (zh) * | 2024-12-02 | 2025-02-25 | 星纯(常州)生物科技有限公司 | 一种无醇磁珠法病毒提取残留检测装置 |
Family Cites Families (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE373963B (https=) | 1973-06-14 | 1975-02-17 | Janson Sven Olof | |
| GB1445389A (en) * | 1973-10-16 | 1976-08-11 | Chemlab Mfg Ltd | Sampling arrangements |
| US3853092A (en) | 1973-10-25 | 1974-12-10 | Corning Glass Works | Apparatus for nutating and staining a microscope slide |
| US4043292A (en) | 1975-07-21 | 1977-08-23 | Corning Glass Works | Microscope slide staining apparatus having temperature control |
| US4092952A (en) | 1977-08-19 | 1978-06-06 | Wilkie Ronald N | Automatic slide stainer |
| SE7801564L (sv) | 1978-02-10 | 1979-08-11 | Lkb Produkter Ab | Anordning for infergning av biologiska preparat |
| DE2915248C3 (de) | 1979-04-14 | 1982-01-14 | Gise, Frhr. von, Hardo, Dr.med., 7400 Tübingen | Einrichtung zum automatischen wahlweisen u. exakten Behandeln von Präparaten |
| AT364439B (de) * | 1980-02-12 | 1981-10-27 | List Hans | Einrichtung zur anordnung an einer probeneingabeoeffnung eines analysengeraetes |
| US4647431A (en) | 1980-05-31 | 1987-03-03 | Fuji Photo Film Co., Ltd. | Device for maintaining a constant temperature for chemical analysis |
| US4384193A (en) * | 1981-06-09 | 1983-05-17 | Immulok, Inc. | Incubating device for specimen mounted on glass slides in immunoassays |
| US4430299A (en) | 1981-06-18 | 1984-02-07 | Coulter Electronics, Inc. | Apparatus for monitoring chemical reactions |
| DK536881A (da) * | 1981-12-04 | 1983-06-05 | Radiometer As | Proevebaeger |
| SE451164B (sv) * | 1982-03-22 | 1987-09-07 | Erik Ohlin | Apparat och sett for serieutspedning av en provvetska |
| AT381794B (de) * | 1984-02-02 | 1986-11-25 | Avl Verbrennungskraft Messtech | Analysengeraet zur messung fluessiger oder gasfoermiger proben |
| US4629862A (en) * | 1984-03-28 | 1986-12-16 | Olympus Optical Company Ltd. | Sample heater for use in microscopes |
| US4644807A (en) * | 1985-02-21 | 1987-02-24 | Dionex Corporation | Fluid sample delivery apparatus |
| US4731335A (en) | 1985-09-13 | 1988-03-15 | Fisher Scientific Company | Method for treating thin samples on a surface employing capillary flow |
| JPH0640054B2 (ja) * | 1985-09-20 | 1994-05-25 | 株式会社千代田製作所 | 電子顕微鏡標本作成用包埋装置 |
| US4695430A (en) | 1985-10-31 | 1987-09-22 | Bio/Data Corporation | Analytical apparatus |
| US4858155A (en) | 1985-12-24 | 1989-08-15 | Beckman Instruments, Inc. | Reaction temperature control system |
| US4888998A (en) * | 1986-07-11 | 1989-12-26 | Beckman Instruments, Inc. | Sample handling system |
| DE3773562D1 (de) * | 1986-07-11 | 1991-11-14 | Beckman Instruments Inc | Probenhandhabungsvorrichtung. |
| US4933146A (en) | 1986-07-11 | 1990-06-12 | Beckman Instruments, Inc. | Temperature control apparatus for automated clinical analyzer |
| US5154889A (en) | 1986-08-07 | 1992-10-13 | Fuji Photo Film Co., Ltd. | Chemical analysis apparatus |
| US4721680A (en) * | 1986-08-11 | 1988-01-26 | Multi-Technology, Inc. | Methods of using micro pipette tips |
| FR2606885B1 (fr) * | 1986-11-14 | 1989-08-04 | Abx Sarl | Dispositif de nettoyage d'une aiguille de prelevement d'un liquide |
| US4847208A (en) | 1987-07-29 | 1989-07-11 | Bogen Steven A | Apparatus for immunohistochemical staining and method of rinsing a plurality of slides |
| GB8722902D0 (en) | 1987-09-30 | 1987-11-04 | Shandon Southern Prod | Tissue &c processing |
| US4927765A (en) * | 1988-02-29 | 1990-05-22 | Pharmacia Eni Diagnostics, Inc. | Automatic reagent dispenser |
| FI80147C (fi) * | 1988-04-15 | 1990-04-10 | Kone Oy | Foerfarande foer foerverkligande av val av vaetska vid vaetskedosering i en analysator samt provtagningsanordning. |
| US5597733A (en) * | 1988-07-25 | 1997-01-28 | Precision Systems, Inc. | Automatic multiple-sample multiple-reagent dispensing method in chemical analyzer |
| JPH0718785B2 (ja) * | 1988-09-19 | 1995-03-06 | 株式会社日立製作所 | フローセル装置 |
| US4962041A (en) * | 1988-10-06 | 1990-10-09 | Medical Automation Specialities, Inc. | Method and apparatus for automatic processing and analyzing of blood serum |
| US4865986A (en) | 1988-10-06 | 1989-09-12 | Coy Corporation | Temperature control apparatus |
| FR2641436A1 (https=) | 1988-12-30 | 1990-07-06 | Labo Electronique Physique | |
| US5429803A (en) * | 1991-04-18 | 1995-07-04 | Lamina, Inc. | Liquid specimen container and attachable testing modules |
| US5264182A (en) * | 1989-04-12 | 1993-11-23 | Olympus Optical Co., Ltd. | Sample and reagent delivery device with a probe and probe supporting member for preventing contamination |
| US5093557A (en) | 1989-05-16 | 1992-03-03 | Microscience, Inc. | Substrate heater and heating element |
| CA2017111C (en) * | 1989-06-01 | 1995-10-31 | Andreas Greter | Pipetting insert |
| FR2649018B1 (fr) * | 1989-06-30 | 1991-09-13 | Degremont | Dispositif pour l'introduction d'un liquide dans un milieu constitue par un materiau granulaire, en vue de la fluidisation de ce materiau |
| GB8919145D0 (en) | 1989-08-23 | 1989-10-04 | Royal Postgrad Med School | Apparatus for the in situ hybridisation of slide-mounted cell samples |
| US5089229A (en) | 1989-11-22 | 1992-02-18 | Vettest S.A. | Chemical analyzer |
| US4989623A (en) * | 1989-12-01 | 1991-02-05 | Akzo N.V. | Apparatus and method for cleaning reagent delivery probes |
| CA2035067C (en) * | 1990-02-22 | 1995-06-27 | William M. Blough, Jr. | Fluid mixing device |
| WO1991013350A2 (en) | 1990-03-02 | 1991-09-05 | Tekmar Company | Analyzer transport device |
| US5595707A (en) | 1990-03-02 | 1997-01-21 | Ventana Medical Systems, Inc. | Automated biological reaction apparatus |
| US5075079A (en) * | 1990-05-21 | 1991-12-24 | Technicon Instruments Corporation | Slide analysis system |
| US5207987A (en) | 1990-05-21 | 1993-05-04 | Pb Diagnostic Systems Inc. | Temperature controlled chamber for diagnostic analyzer |
| US5425918A (en) | 1990-07-18 | 1995-06-20 | Australian Biomedical Corporation | Apparatus for automatic tissue staining for immunohistochemistry |
| JP2530738Y2 (ja) * | 1990-11-13 | 1997-03-26 | 株式会社明電舎 | ノズル洗浄ポート |
| KR100236506B1 (ko) | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
| DE69130205T2 (de) | 1990-12-25 | 1999-03-25 | Ngk Insulators, Ltd., Nagoya, Aichi | Heizungsapparat für eine Halbleiterscheibe und Verfahren zum Herstellen desselben |
| US5273905A (en) | 1991-02-22 | 1993-12-28 | Amoco Corporation | Processing of slide mounted material |
| US5246665A (en) | 1991-06-03 | 1993-09-21 | Abbott Laboratories | Heat and air flow control for assay carrier |
| CA2074214C (en) * | 1991-07-23 | 2000-02-22 | Will Bloch | Improvements in the in situ pcr |
| GB9123463D0 (en) | 1991-11-05 | 1991-12-18 | Hybaid Ltd | Reaction temperature control device |
| FI915731A0 (fi) | 1991-12-05 | 1991-12-05 | Derek Henry Potter | Foerfarande och anordning foer reglering av temperaturen i ett flertal prov. |
| FR2688313A1 (fr) * | 1992-03-04 | 1993-09-10 | Marteau D Autry Eric | Filtration et identification automatique d'echantillons. |
| US5316452A (en) | 1992-05-11 | 1994-05-31 | Gilbert Corporation | Dispensing assembly with interchangeable cartridge pumps |
| US5947167A (en) * | 1992-05-11 | 1999-09-07 | Cytologix Corporation | Dispensing assembly with interchangeable cartridge pumps |
| US5645114A (en) * | 1992-05-11 | 1997-07-08 | Cytologix Corporation | Dispensing assembly with interchangeable cartridge pumps |
| US5314825A (en) * | 1992-07-16 | 1994-05-24 | Schiapparelli Biosystems, Inc. | Chemical analyzer |
| US5601141A (en) | 1992-10-13 | 1997-02-11 | Intelligent Automation Systems, Inc. | High throughput thermal cycler |
| US5408891A (en) | 1992-12-17 | 1995-04-25 | Beckman Instruments, Inc. | Fluid probe washing apparatus and method |
| US5364790A (en) * | 1993-02-16 | 1994-11-15 | The Perkin-Elmer Corporation | In situ PCR amplification system |
| JP3323294B2 (ja) * | 1993-09-14 | 2002-09-09 | 富士写真フイルム株式会社 | 点着チップおよびこの点着チップを用いた液体濃縮防止方法 |
| US5439649A (en) | 1993-09-29 | 1995-08-08 | Biogenex Laboratories | Automated staining apparatus |
| JP3051626B2 (ja) | 1993-12-09 | 2000-06-12 | 富士写真フイルム株式会社 | インキュベータ |
| US5523056A (en) | 1994-04-29 | 1996-06-04 | Johnson & Johnson Clinical Diagnostics, Inc. | Twin rotor incubator assembly |
| JP3387649B2 (ja) * | 1994-09-16 | 2003-03-17 | 富士写真フイルム株式会社 | 点着チップ |
| EP0729021A1 (de) * | 1995-02-25 | 1996-08-28 | Roche Diagnostics GmbH | Vorrichtung zur Bearbeitung von Proben auf Objektträgern |
| US5645144A (en) * | 1995-08-22 | 1997-07-08 | A-Dec, Inc. | Control mechanism for sliding panel |
| ES2245462T3 (es) * | 1996-04-26 | 2006-01-01 | Dade Behring Inc. | Procedimiento y aparato para retratar muestras en un analizador quimico automatico. |
| US6183693B1 (en) | 1998-02-27 | 2001-02-06 | Cytologix Corporation | Random access slide stainer with independent slide heating regulation |
| US6096271A (en) * | 1998-02-27 | 2000-08-01 | Cytologix Corporation | Random access slide stainer with liquid waste segregation |
| CN1774836B (zh) * | 2002-12-09 | 2010-09-08 | 科里多系统公司 | 发射表面波至单导体传输线的方法及装置 |
| US20100128351A1 (en) * | 2008-11-21 | 2010-05-27 | 3M Innovative Properties Company | Curved sided cone structures for controlling gain and viewing angle in an optical film |
-
1999
- 1999-02-26 JP JP2000533730A patent/JP3847559B2/ja not_active Expired - Lifetime
- 1999-02-26 CA CA002321836A patent/CA2321836C/en not_active Expired - Lifetime
- 1999-02-26 EP EP99909681.1A patent/EP1056541B1/en not_active Expired - Lifetime
- 1999-02-26 AT AT99909630T patent/ATE489613T1/de not_active IP Right Cessation
- 1999-02-26 WO PCT/US1999/004181 patent/WO1999044030A1/en not_active Ceased
- 1999-02-26 EP EP10179439.4A patent/EP2284543A3/en not_active Ceased
- 1999-02-26 AU AU28834/99A patent/AU2883499A/en not_active Abandoned
- 1999-02-26 DE DE69942975T patent/DE69942975D1/de not_active Expired - Lifetime
- 1999-02-26 EP EP99909630A patent/EP1073892B1/en not_active Expired - Lifetime
- 1999-02-26 US US09/259,240 patent/US6296809B1/en not_active Expired - Lifetime
- 1999-02-26 CN CNB998050288A patent/CN100403008C/zh not_active Expired - Lifetime
- 1999-02-26 CA CA002320750A patent/CA2320750C/en not_active Expired - Lifetime
- 1999-02-26 WO PCT/US1999/004379 patent/WO1999043434A1/en not_active Ceased
- 1999-02-26 JP JP2000533222A patent/JP2002504694A/ja active Pending
- 1999-02-26 AU AU28796/99A patent/AU763354B2/en not_active Expired
- 1999-02-26 ES ES99909630T patent/ES2354598T3/es not_active Expired - Lifetime
-
2003
- 2003-10-17 AU AU2003255169A patent/AU2003255169A1/en not_active Abandoned
-
2006
- 2006-07-11 JP JP2006190677A patent/JP4091960B2/ja not_active Expired - Lifetime
-
2009
- 2009-05-18 JP JP2009120016A patent/JP4505538B2/ja not_active Expired - Lifetime
- 2009-12-14 JP JP2009282843A patent/JP4505547B2/ja not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10746752B2 (en) | 2009-11-13 | 2020-08-18 | Ventana Medical Systems, Inc. | Opposables and automated specimen processing systems with opposables |
| KR20150095832A (ko) * | 2012-12-26 | 2015-08-21 | 벤타나 메디컬 시스템즈, 인코포레이티드 | 검체 프로세싱 시스템들 및 슬라이드들을 균일하게 가열하는 방법들 |
| KR101719939B1 (ko) * | 2012-12-26 | 2017-03-24 | 벤타나 메디컬 시스템즈, 인코포레이티드 | 검체 프로세싱 시스템들 및 슬라이드들을 균일하게 가열하는 방법들 |
| JP2020510196A (ja) * | 2017-03-16 | 2020-04-02 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. | 診断分析装置におけるインキュベーションシステムの温度制御のためのシステム及び方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100403008C (zh) | 2008-07-16 |
| WO1999044030A1 (en) | 1999-09-02 |
| JP4091960B2 (ja) | 2008-05-28 |
| EP1056541A4 (en) | 2005-11-30 |
| AU763354B2 (en) | 2003-07-17 |
| CA2321836C (en) | 2004-09-28 |
| CA2320750A1 (en) | 1999-09-02 |
| WO1999044030A9 (en) | 1999-12-16 |
| JP2002504694A (ja) | 2002-02-12 |
| JP2010091579A (ja) | 2010-04-22 |
| CN1297529A (zh) | 2001-05-30 |
| JP4505538B2 (ja) | 2010-07-21 |
| JP2009216714A (ja) | 2009-09-24 |
| EP1073892B1 (en) | 2010-11-24 |
| EP1056541B1 (en) | 2017-10-25 |
| EP2284543A3 (en) | 2015-05-27 |
| CA2320750C (en) | 2004-08-24 |
| DE69942975D1 (de) | 2011-01-05 |
| JP2006304806A (ja) | 2006-11-09 |
| ATE489613T1 (de) | 2010-12-15 |
| JP2002505089A (ja) | 2002-02-19 |
| EP1056541A1 (en) | 2000-12-06 |
| AU2879699A (en) | 1999-09-15 |
| EP1073892A4 (en) | 2005-10-12 |
| EP1073892A1 (en) | 2001-02-07 |
| AU2003255169A1 (en) | 2003-11-13 |
| US6296809B1 (en) | 2001-10-02 |
| JP4505547B2 (ja) | 2010-07-21 |
| ES2354598T3 (es) | 2011-03-16 |
| EP2284543A2 (en) | 2011-02-16 |
| WO1999043434A1 (en) | 1999-09-02 |
| CA2321836A1 (en) | 1999-09-02 |
| AU2883499A (en) | 1999-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3847559B2 (ja) | 独立スライド加熱器を有する自動化分子病理学装置 | |
| US6582962B1 (en) | Automated molecular pathology apparatus having independent slide heaters | |
| US7396508B1 (en) | Automated molecular pathology apparatus having independent slide heaters | |
| US20030211630A1 (en) | Automated molecular pathology apparatus having independent slide heaters | |
| US6300124B1 (en) | Device and method to directly control the temperature of microscope slides | |
| US7404927B2 (en) | Automated molecular pathology apparatus having fixed slide platforms | |
| AU2003228709B2 (en) | Automated molecular pathology apparatus having fixed slide platforms | |
| EP3591374B1 (en) | An apparatus and method for processing biological samples | |
| DK1337831T3 (en) | REMOVAL OF BIOLOGICAL SAMPLING AND CELL CONDITIONING MEDIA ON AUTOMATIC DYING INSTRUMENTS | |
| JP2004525366A (ja) | 自動免疫組織化学およびイン・サイチュ・ハイブリダイゼーションのアッセイ処方 | |
| EP0968306A1 (en) | Thermal cycling or temperature control device and method using alumina plate | |
| JP2003510571A (ja) | 組織試料中の分子標的の臨床的有用性を評価するための高処理量システム | |
| JP2009058288A (ja) | 液体試料分注方法、加温装置、並びに液体試料の自動分注方法および自動分注装置 | |
| Takahashi et al. | Development of an automatic machine for in situ hybridization and immunohistochemistry | |
| CN111801676A (zh) | 防雾条形码读取器 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20050427 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20050517 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050816 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20050913 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20051213 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20051228 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060310 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20060411 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060711 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20060815 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20060823 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20090901 Year of fee payment: 3 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100901 Year of fee payment: 4 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20110901 Year of fee payment: 5 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20110901 Year of fee payment: 5 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120901 Year of fee payment: 6 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130901 Year of fee payment: 7 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |