BR112013017366A2 - processo automatizado para coloração de uma amostra biológica compreendendo células e sistema para coloração de uma amostra biológica montado em um substrato - Google Patents

processo automatizado para coloração de uma amostra biológica compreendendo células e sistema para coloração de uma amostra biológica montado em um substrato

Info

Publication number
BR112013017366A2
BR112013017366A2 BR112013017366A BR112013017366A BR112013017366A2 BR 112013017366 A2 BR112013017366 A2 BR 112013017366A2 BR 112013017366 A BR112013017366 A BR 112013017366A BR 112013017366 A BR112013017366 A BR 112013017366A BR 112013017366 A2 BR112013017366 A2 BR 112013017366A2
Authority
BR
Brazil
Prior art keywords
staining
biological sample
cells
substrate
automated process
Prior art date
Application number
BR112013017366A
Other languages
English (en)
Inventor
Bryan W Barnes
Charles H Weidner
Original Assignee
Ventana Med Syst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Med Syst Inc filed Critical Ventana Med Syst Inc
Publication of BR112013017366A2 publication Critical patent/BR112013017366A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

processo automatizado para coloração de uma amostra biológica compreendendo células e sistema para coloração de uma amostra biológica montado em um substrato a presente invenção refere-se a processos para a coloração de amostras biológicas e, em particular para processos automatizados para coloração de amostra biológica com corante hematoxilina. nos processos e sistemas da invenção, as soluções de hemateína e mordente separadas são forncecidas, a qual podem ser pré-misturadas antes da aplicação a uma amostra biológica. este método previne a precipitação comum em soluções de coloração de hemateína e a qual obstrui o equipamento automatizado de processamento de lâminas/amostras.
BR112013017366A 2011-01-10 2012-01-06 processo automatizado para coloração de uma amostra biológica compreendendo células e sistema para coloração de uma amostra biológica montado em um substrato BR112013017366A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161431111P 2011-01-10 2011-01-10
PCT/US2012/020483 WO2012096842A1 (en) 2011-01-10 2012-01-06 Hematoxylin staining method

Publications (1)

Publication Number Publication Date
BR112013017366A2 true BR112013017366A2 (pt) 2016-10-04

Family

ID=45532057

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013017366A BR112013017366A2 (pt) 2011-01-10 2012-01-06 processo automatizado para coloração de uma amostra biológica compreendendo células e sistema para coloração de uma amostra biológica montado em um substrato

Country Status (9)

Country Link
US (1) US20130302852A1 (pt)
EP (1) EP2663852A1 (pt)
JP (1) JP2014505248A (pt)
KR (1) KR20140002694A (pt)
CN (1) CN103415762A (pt)
AU (1) AU2012205849A1 (pt)
BR (1) BR112013017366A2 (pt)
CA (1) CA2822451A1 (pt)
WO (1) WO2012096842A1 (pt)

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Publication number Priority date Publication date Assignee Title
AU2014363678B2 (en) 2013-12-13 2016-12-08 Ventana Medical Systems, Inc. Staining reagents and other liquids for histological processing of biological specimens and associated technology
CN104744967B (zh) * 2013-12-31 2018-01-02 江苏省原子医学研究所 一种伊红染色液及其含伊红染色液的he染色液
MA42105A (fr) * 2015-05-22 2018-03-28 Ventana Med Syst Inc Procédés et appareil pour éliminer ou réduire la formation de précipités générés dans des solutions d'hématoxyline
CN105067412B (zh) * 2015-08-10 2018-06-26 迪瑞医疗科技股份有限公司 一种阴道分泌物染色液及其制备方法与染色方法
KR20180081561A (ko) 2015-11-06 2018-07-16 벤타나 메디컬 시스템즈, 인코포레이티드 대표 진단법
CA3007159C (en) 2015-12-30 2022-08-23 Ventana Medical Systems, Inc. System and method for real time assay monitoring
US20180252622A1 (en) 2017-03-06 2018-09-06 United Arab Emirates University A Stain for Staining Cells, the Use of the Stain in Histological Applications and a Method of Diagnosis
CN110621974A (zh) * 2017-05-10 2019-12-27 文塔纳医疗系统公司 利用pH调节的稳定的两部分苏木精溶液
EP3639080B1 (en) * 2017-06-15 2023-12-13 Shenzhen PRS Limited Process record slide for special staining
CN108195653A (zh) * 2017-09-16 2018-06-22 南京福怡科技发展股份有限公司 一种复染染色试剂盒及制备和应用
JP7038209B2 (ja) 2017-11-13 2022-03-17 エフ．ホフマン－ラ ロシュ アーゲー エピタコ電気泳動を使用する試料分析のための装置
EP3729047A2 (en) 2017-12-24 2020-10-28 Ventana Medical Systems, Inc. Eosin staining techniques
CN108801741B (zh) * 2018-03-30 2021-04-02 迈克生物股份有限公司 用于免疫组化染色的苏木素复染液及染色方法
WO2020074742A1 (en) 2018-10-12 2020-04-16 F. Hoffmann-La Roche Ag Detection methods for epitachophoresis workflow automation
CN109406246A (zh) * 2018-10-25 2019-03-01 潍坊市康华生物技术有限公司 一种精子形态学快速染色试剂及其染色方法
CN111829858A (zh) * 2019-04-18 2020-10-27 湖北文理学院 实验发现两种简单、低廉、来源丰富的新型组织切片染色剂
US20220325268A1 (en) 2019-05-14 2022-10-13 Roche Sequencing Solutions, Inc Devices and methods for sample analysis
EP4147024A2 (en) * 2020-05-08 2023-03-15 Ventana Medical Systems, Inc. Semi-synthesis and use of racemic hematoxylin
IT202100018434A1 (it) * 2021-07-13 2023-01-13 Diapath S P A Composizioni coloranti per campioni biologici, citologici, istologici e autoptici.
CN113790945B (zh) * 2021-09-23 2024-02-20 南昌雨露实验器材有限公司 一种改良的苏木精染液及其制备方法
WO2023107588A1 (en) * 2021-12-08 2023-06-15 University Of Washington Methods and systems for imaging biopsy samples

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GB673441A (en) * 1950-04-18 1952-06-04 Technicon Chemical Company Inc Method of staining slides and staining solutions therefor
JPH0244309B2 (ja) * 1982-09-16 1990-10-03 Wako Pure Chem Ind Ltd Anteinahematokishirinyozai
US5009185A (en) * 1989-05-09 1991-04-23 Wescor, Inc. Apparatus for applying a controlled amount of reagent to a microscope slide or the like
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US6296809B1 (en) 1998-02-27 2001-10-02 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US6582962B1 (en) 1998-02-27 2003-06-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
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EP1082611A4 (en) * 1998-06-02 2003-01-15 Ventana Med Syst Inc METHODS OF COLORING BIOLOGICAL SAMPLES BY COMBINING REAGENTS INSTABLE ON THE OBJECT BLADE
CN1181344C (zh) * 2000-06-12 2004-12-22 韩亚京 一种氧化苏木色精液及其制备方法和用途
US6858432B2 (en) * 2002-08-29 2005-02-22 Wescor, Inc. Method and staining reagent for staining hematology sample in an automated staining apparatus
US7648678B2 (en) * 2002-12-20 2010-01-19 Dako Denmark A/S Method and system for pretreatment of tissue slides
US8263361B2 (en) 2007-03-15 2012-09-11 Ventana Medical Systems, Inc. Stabilized hematoxylin
CN100567943C (zh) * 2007-04-27 2009-12-09 孝感学院 一种骨骼肌横纹的切片染色方法
US8158381B2 (en) * 2008-03-27 2012-04-17 Richard-Allan Scientific Company Methods for integrated tissue processing and staining

Also Published As

Publication number Publication date
JP2014505248A (ja) 2014-02-27
KR20140002694A (ko) 2014-01-08
WO2012096842A1 (en) 2012-07-19
CN103415762A (zh) 2013-11-27
CA2822451A1 (en) 2012-07-19
US20130302852A1 (en) 2013-11-14
AU2012205849A1 (en) 2013-07-04
EP2663852A1 (en) 2013-11-20

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]