JP2842453B2 - 生体内に注入可能な安定な微小泡懸濁液 - Google Patents

生体内に注入可能な安定な微小泡懸濁液

Info

Publication number
JP2842453B2
JP2842453B2 JP3506829A JP50682991A JP2842453B2 JP 2842453 B2 JP2842453 B2 JP 2842453B2 JP 3506829 A JP3506829 A JP 3506829A JP 50682991 A JP50682991 A JP 50682991A JP 2842453 B2 JP2842453 B2 JP 2842453B2
Authority
JP
Japan
Prior art keywords
suspension
gas
air
microbubbles
phospholipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP3506829A
Other languages
English (en)
Japanese (ja)
Other versions
JPH04506670A (ja
Inventor
シュネイダー，ミシェル
ビション，ダニエル
ブサ，フィリップ
プギニエ，ジェロム
イブル，エバ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BURATSUKO INTERN BV
Original Assignee
BURATSUKO INTERN BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8205915&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2842453(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BURATSUKO INTERN BV filed Critical BURATSUKO INTERN BV
Publication of JPH04506670A publication Critical patent/JPH04506670A/ja
Application granted granted Critical
Publication of JP2842453B2 publication Critical patent/JP2842453B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Catching Or Destruction (AREA)
  • Farming Of Fish And Shellfish (AREA)
JP3506829A 1990-04-02 1991-04-02 生体内に注入可能な安定な微小泡懸濁液 Expired - Lifetime JP2842453B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90810262 1990-04-02
EP90810262.7 1990-04-02

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP18050498A Division JP4205779B2 (ja) 1990-04-02 1998-06-26 生体内に注入可能な安定な微小泡懸濁液

Publications (2)

Publication Number Publication Date
JPH04506670A JPH04506670A (ja) 1992-11-19
JP2842453B2 true JP2842453B2 (ja) 1999-01-06

Family

ID=8205915

Family Applications (3)

Application Number Title Priority Date Filing Date
JP3506829A Expired - Lifetime JP2842453B2 (ja) 1990-04-02 1991-04-02 生体内に注入可能な安定な微小泡懸濁液
JP18050498A Expired - Lifetime JP4205779B2 (ja) 1990-04-02 1998-06-26 生体内に注入可能な安定な微小泡懸濁液
JP2003050459A Pending JP2003221350A (ja) 1990-04-02 2003-02-27 生体内に注入可能な安定な微小泡懸濁液

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP18050498A Expired - Lifetime JP4205779B2 (ja) 1990-04-02 1998-06-26 生体内に注入可能な安定な微小泡懸濁液
JP2003050459A Pending JP2003221350A (ja) 1990-04-02 2003-02-27 生体内に注入可能な安定な微小泡懸濁液

Country Status (19)

Country Link
US (13) US5271928A (enExample)
EP (1) EP0474833B2 (enExample)
JP (3) JP2842453B2 (enExample)
KR (1) KR960002184B1 (enExample)
CN (1) CN1055413C (enExample)
AT (1) ATE125711T1 (enExample)
AU (1) AU630030B2 (enExample)
CA (1) CA2056371C (enExample)
DE (1) DE69111719T3 (enExample)
DK (1) DK0474833T4 (enExample)
ES (1) ES2075438T5 (enExample)
GR (1) GR3017324T3 (enExample)
IE (1) IE69018B1 (enExample)
IL (1) IL97730A (enExample)
IN (1) IN172208B (enExample)
IS (1) IS3686A7 (enExample)
NZ (1) NZ237637A (enExample)
WO (1) WO1991015244A2 (enExample)
ZA (1) ZA912427B (enExample)

Families Citing this family (345)

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US5531980A (en) 1996-07-02
EP0474833A1 (en) 1992-03-18
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