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US20060111744A1 - Method and system for treatment of sweat glands - Google Patents

Method and system for treatment of sweat glands Download PDF

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Publication number
US20060111744A1
US20060111744A1 US11163152 US16315205A US2006111744A1 US 20060111744 A1 US20060111744 A1 US 20060111744A1 US 11163152 US11163152 US 11163152 US 16315205 A US16315205 A US 16315205A US 2006111744 A1 US2006111744 A1 US 2006111744A1
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Prior art keywords
treatment
system
transducer
configured
exemplary
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Abandoned
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US11163152
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Inder Raj Makin
Peter Barthe
Michael Slayton
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GUIDED THERAPY SYSTEMS LLC
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GUIDED THERAPY SYSTEMS LLC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N7/02Localised ultrasound hyperthermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/320068Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42Details of probe positioning or probe attachment to the patient
    • A61B8/4272Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue
    • A61B8/4281Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue characterised by sound-transmitting media or devices for coupling the transducer to the tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0004Applications of ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0052Ultrasound therapy using the same transducer for therapy and imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0078Ultrasound therapy with multiple treatment transducers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy

Abstract

A method and system for ultrasound treatment of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.

Description

    CROSS-REFERENCE TO RELATED APPLICATIONS
  • [0001]
    Application claims priority to and benefit of U.S. Provisional Application No. 60/61 7,752, entitled “Method and System for Treatment of Sweat Glands”, and filed on Oct. 6, 2004.
  • FIELD OF INVENTION
  • [0002]
    This invention generally relates to a therapeutic ultrasound method and system, and more particularly, to a method and system for ultrasound treatment for superficial tissue containing sweat glands.
  • BACKGROUND OF INVENTION
  • [0003]
    The sweat glands in the body are of divided into apocrine and eccrine glands. Apocrine glands are similar to sebaceous glands, and are present mainly in the axillae. These glands, like sebaceous glands, secrete an oily proteinaceous product into the follicles. Bacterial digestion of apocrine sweat is largely responsible for underarm “body odor”. Similarly, eccrine sweat glands are present deep in the dermis in the palms, soles and armpits and are responsible for temperature regulation resulting from sweating. Excessive activity of these glands also results in copious amounts of abnormal sweating (“hyperhidrosis”), primarily under autonomic neuronal control. Reduction of sweating from under the armpits and other regions is a particularly desirable effect within the modern society. Presently, chemical antiperspirants and deodorants are used frequently as a matter of personal hygiene. Antiperspirants are aluminum based salts that block the sweat gland ducts. The deodorant changes the pH of the skin milieu thereby minimizing the presence of (smell inducing) bacteria. The effects with both these components however, are temporary and these chemicals are known to irritate the skin in a good percentage of users.
  • [0004]
    Further, there is currently a significant unmet need in managing the excessive sweating and concomitant issues with odor as a result of Hydradenitis suppurativa (irritable infected armpit). This acne-like process in apocine follicles also causes hydradenitis suppurativa, which is often a devastating condition in which very painful cysts and scarring occurs repeatedly in the axillae. The etiology (causes) of this clinical condition is not well understood. However, there are a number of marginally effective approaches to manage this condition. Retinoid drug therapy works marginally but is associated with severe toxicity. Some prescription formulations of antiperspirants can be used, but they are not particularly effective. These preparations can be applied with the addition of an iontophoretic device. This technique however, is not known to be any more effective than the formulation. The sweat glands can be surgically removed from the armpits and/or the sympathetic nerve supply can be interrupted surgically. This approach is fraught with its own drawbacks in terms of morbidity, scarring and cost. BOTOX® is being used ever more for paralyzing the nerve connections that induce excessive sweating in the armpits. However, this is a new approach yet to be completely validated. This technique requires multiple injections (painful) and the results last a few months only (3-4 months), hence need to be repeated. This technique does not get rid of the odor associated with the condition.
  • SUMMARY OF INVENTION
  • [0005]
    The present invention describes a non-invasive method and system for using therapeutic ultrasound energy for the treatment of conditions resulting from sweat gland disorders. An ultrasound system and method comprises a transducer probe and control system configured to deliver ultrasound energy to the regions of the superficial tissue (e.g., skin) such that the energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.
  • [0006]
    In accordance with various exemplary embodiments, the ultrasound transducer can be driven at a number of different frequency regimes such that the depth and shape of energy concentration can match the region of treatment. In addition, the ultrasound source or beam radiated from the transducer can be highly focused, weakly focused, or divergent, each in a cylindrical or spherical geometric configuration, and/or can also be planar to radiate a directive beam through the tissue, or various other configurations. Further, the ultrasound field can be varied spatially and temporally in a suitable manner to achieve the optimal tissue effect and/or type of conformal lesion for treating the sweat glands.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0007]
    The subject matter of the invention is particularly pointed out in the concluding portion of the specification. The invention, however, both as to organization and method of operation, may best be understood by reference to the following description taken in conjunction with the accompanying drawing figures, in which like parts may be referred to by like numerals:
  • [0008]
    FIG. 1 illustrates a block diagram of an ultrasound therapy system for treating sweat glands in accordance with an exemplary embodiment of the present invention;
  • [0009]
    FIG. 2A-2E illustrates schematic diagrams of ultrasound treatment systems configured to treat the sweat glands via direct targeting of heating and damage within the treatment layer in accordance with various exemplary embodiments of the present invention;
  • [0010]
    FIGS. 3A and 3B illustrate block diagrams of an exemplary control system in accordance with exemplary embodiments of the present invention;
  • [0011]
    FIGS. 4A and 4B illustrate block diagrams of an exemplary probe system in accordance with exemplary embodiments of the present invention;
  • [0012]
    FIG. 5 illustrates a cross-sectional diagram of an exemplary transducer in accordance with an exemplary embodiment of the present invention;
  • [0013]
    FIGS. 6A and 6B illustrate cross-sectional diagrams of an exemplary transducer in accordance with exemplary embodiments of the present invention;
  • [0014]
    FIG. 7 illustrates exemplary transducer configurations for ultrasound treatment in accordance with various exemplary embodiments of the present invention;
  • [0015]
    FIGS. 8A and 8B illustrate cross-sectional diagrams of an exemplary transducer in accordance with another exemplary embodiment of the present invention;
  • [0016]
    FIG. 9 illustrates an exemplary transducer configured as a two-dimensional array for ultrasound treatment in accordance with an exemplary embodiment of the present invention;
  • [0017]
    FIGS. 10A-10F illustrate cross-sectional diagrams of exemplary transducers in accordance with other exemplary embodiments of the present invention;
  • [0018]
    FIG. 11 illustrates a schematic diagram of an acoustic coupling and cooling system in accordance with an exemplary embodiment of the present invention;
  • [0019]
    FIG. 12 illustrates a block diagram of an ultrasound treatment system combined with additional subsystems and methods of treatment monitoring and/or treatment imaging as well as a secondary treatment subsystem in accordance with an exemplary embodiment of the present invention; and
  • [0020]
    FIG. 13 illustrates a schematic diagram with imaging, therapy, or monitoring being provided with one or more active or passive oral inserts in accordance with an exemplary embodiment of the present invention.
  • DETAILED DESCRIPTION
  • [0021]
    The present invention may be described herein in terms of various components and processing steps. It should be appreciated that such components and steps may be realized by any number of hardware components configured to perform the specified functions. For example, the present invention may be configured with various medical treatment devices, visual imaging and display devices, input terminals and the like, which may carry out a variety of functions under the control of one or more control systems or other control devices. In addition, the present invention may be practiced in any number of medical or treatment contexts and that the exemplary embodiments relating to a method and system for sweat gland treatment as described herein are merely a few of the exemplary applications for the invention. For example, the principles, features and methods discussed may be applied to any medical or other tissue or treatment application.
  • [0022]
    In accordance with various aspects of the present invention, a non-invasive method and system for the treatment of sweat glands is described. In accordance with an exemplary embodiment, an ultrasound transducer probe and control system are configured to deliver ultrasound energy to a targeted/specified depth and zone where the sweat gland population is required to be treated. The ultrasound beam from the transducer probe can be spatially and/or temporally adjusted, modified or otherwise controlled to match the adequate treatment of the sweat glands in the region of interest.
  • [0023]
    For example, in accordance with an exemplary embodiment, with reference to FIG. 1, an exemplary treatment system 100 configured to treat a region of interest (ROI) 106 comprises a control system 102, an imaging/therapy probe with acoustic coupling 104, and a display system 108.
  • [0024]
    Control system 102 and display 108 can comprise various configurations for controlling functionality of probe 104 and system 100, including for example a microprocessor with software and a plurality of input/output and communication devices, a system for controlling electronic and/or mechanical scanning and/or multiplexing of transducers, a system for power delivery, systems for monitoring, systems for sensing the spatial parameters and/or temporal parameters of the probe and transducers, and/or systems for handling user input and recording treatment input and results, among others. Imaging/therapy probe 104 can comprise various probe and/or transducer configurations. For example, probe 104 can be configured for a combined dual-mode imaging/therapy transducer, coupled or co-housed imaging/therapy transducers, a separate therapy probe and separate imaging probe, or a single therapy probe. In accordance with exemplary embodiments, imaging transducers may operate at frequencies from approximately 2 MHz to 75 MHz or more, while therapy energy can be delivered at frequencies from approximately 500 kHz to 15 MHz, with 2 MHz to 25 MHz being typical.
  • [0025]
    With reference to FIG. 2A, sweat glands 230 are generally located within a dermis layer 214 at a depth close to hair bulbs 236. In order to treat sweat glands that require treatment in particular anatomical sites, such as, for example but not limited to, the axillary region (armpit), the palms and soles, an ultrasound transducer probe can be coupled to the skin tissue using one of the numerous coupling media, such as water, mineral oils, gels, and the like.
  • [0026]
    For example, with reference to FIG. 2B, in accordance with an exemplary embodiment an exemplary treatment method and system are configured for initially imaging a region 222 within a region of interest 206 and displaying that region 224 on a display 208 to facilitate localization of the treatment area and surrounding structures, e.g., identification of sweat glands 230, such as within the axillary region (armpit), the palms and soles or any other tissue or skin surrounding sweat glands. After localization, delivery of ultrasound energy 220 at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect of thermal ablation to treat a sweat gland 230 is provided. Before, during, and/or after therapy, i.e., before, during and/or after delivery of ultrasound energy, monitoring of the treatment area and surrounding structures can be conducted to further planning and assessing of the results and/or providing feedback to control system 202 and a system operator.
  • [0027]
    In accordance with an exemplary embodiment, localization can be facilitated through ultrasound imaging that can be used to define the position of a sweat gland 230 and/or the depth of sweat glands 230 over a region of interest before depositing in a defined pattern at a target region 220. Such glands can be seen lying along hair follicles 232 and bulbs 236 and their image may be further enhanced via signal and image processing. Ultrasound imaging can also be used for safety purposes, namely, to avoid injuring vital structures, such as nerve endings 240. In accordance with other exemplary embodiments, localization can also be accomplished without imaging region 222, but instead can be based on prior known depths of sweat glands or other target regions, and thus be configured geometrically and/or electronically to selectively deposit energy at a particular known depth below skin surface 210 to a target region 220.
  • [0028]
    The ultrasound beam from probe 204 can be spatially and/or temporally controlled by changing the spatial parameters of the transducer, such as the placement, distance, treatment depth and transducer structure, as well as by changing the temporal parameters of transducer, such as the frequency, drive amplitude, and timing, with such control handled via control system 202. For example, in some applications, the temporal energy exposure at one location may range from approximately to 40 ms to 40 seconds, while the corresponding source frequency can suitably range from approximately 500 kHz to 15 MHz. Such spatial and temporal parameters can also be suitably monitored and/or utilized in open-loop and/or closed-loop feedback systems within treatment system 200. As a result of such spatial and/or temporal control, conformal lesions of various, specifically targeted, shapes, sizes and orientations can be configured within target region 220.
  • [0029]
    In accordance with an exemplary embodiment, the treatment resulting from ultrasound energy delivery in the region of sweat glands 230 can be used to achieve selective ablation of regions of sub-epidermal region (0.5-10 mm diameter zones). For example, one or more treated zones 242 can be configured to produce regions of ablative damage in spatially defined patterns, such as a discrete locus of spaced treatment spots or two- or three- dimensional matrix of damage or destroyed tissue, e.g., a matrix of cross-stitched, ellipsoidal/cigar-shaped, wedge-shaped, mushroom-shaped or any other conformal lesions, rather than heating and destroying the entire volume of the target layer of tissue. In such a treatment where surrounding regions are spared of damage, the surrounding undamaged tissue aids rapid healing and recovery.
  • [0030]
    In accordance with another exemplary embodiment, a whole contiguous sheet of treatment area can be achieved, whereby all the sweat glands within the said area are ablated. In addition to selective treatment of sweat gland regions, in accordance with another exemplary embodiment, treatment system 200 could be configured to “carpet bomb” the fat layer at 1-7 mm depth, e.g., up to 90% of the sweat glands in the armpit can be ablated without any physiologic issues.
  • [0031]
    In accordance with another exemplary embodiment of the present invention, an exemplary monitoring method may comprise monitoring the temperature profile or other tissue parameters of the region of interest 206, such as attenuation, speed of sound, or mechanical properties such as stiffness and strain of the treatment region and suitably adjust the spatial and/or temporal characteristics and energy levels of the ultrasound therapy transducer of probe 204. The results of such monitoring techniques may be indicated on display 208 by means of one-, two-, or three-dimensional images of monitoring results 250, or may simply comprise a success or fail-type indicator 252, or combinations thereof. Additional treatment monitoring techniques may be based on one or more of temperature, video, profilometry, and/or stiffness or strain gauges or any other suitable sensing technique.
  • [0032]
    The non-thermal effects from an acoustic field can also “shock” the sweat producing apocrine and eccrine cells in to reduced activity. These effects mentioned here as examples are, but not limited to, acoustic cavitation, acoustic streaming, inter-cellular shear effects, cell resonant effects, and the like.
  • [0033]
    In accordance with an exemplary embodiment, focused or directive ultrasound energy can be used for the treatment of sweat glands in the armpit (without the combination of pharmacological formulations). For example, a clinical indication would be to use in the management of Hidradenitis suppurativa. Ultrasound energy deposited at a selective depth can also be used in combination with a number of pharmaceutical formulations that are currently prescribed for the treatment of sweat gland hyperactivity in the axillary region, palms and soles. The ultrasound energy delivered to the target region in combination with the pharmaceutical agents such as BOTOX® or retinoids can help synergistically treat the sweat gland region by, (1) increasing activity of the agents due to the thermal and non-thermal mechanisms, (2) reduced requirement of overall drug dosage, as well as reducing the drug toxicity, (3) increase local effect of drug in a site selective manner.
  • [0034]
    An exemplary control system 202 and display system 208 may be configured in various manners for controlling probe and system functionality for providing the various exemplary treatment methods illustrated above. For example, with reference to FIGS. 3A and 3B, in accordance with exemplary embodiments, an exemplary control system 300 can be configured for coordination and control of the entire therapeutic treatment process to achieve the desired therapeutic effect of thermal ablation to treat a sweat gland. For example, control system 300 can suitably comprise power source components 302, sensing and monitoring components 304, cooling and coupling controls 306, and/or processing and control logic components 308. Control system 300 can be configured and optimized in a variety of ways with more or less subsystems and components to implement the therapeutic system for controlled thermal injury of sweat glands, and the embodiments in FIGS. 3A and 3B are merely for illustration purposes.
  • [0035]
    For example, for power sourcing components 302, control system 300 can comprise one or more direct current (DC) power supplies 303 configured to provide electrical energy for entire control system 300, including power required by a transducer electronic amplifier/driver 312. A DC current sense device 305 can also be provided to confirm the level of power going into amplifiers/drivers 312 for safety and monitoring purposes.
  • [0036]
    Amplifiers/drivers 312 can comprise multi-channel or single channel power amplifiers and/or drivers. In accordance with an exemplary embodiment for transducer array configurations, amplifiers/drivers 312 can also be configured with a beamformer to facilitate array focusing. An exemplary beamformer can be electrically excited by an oscillator/digitally controlled waveform synthesizer 310 with related switching logic.
  • [0037]
    The power sourcing components can also include various filtering configurations 314. For example, switchable harmonic filters and/or matching may be used at the output of amplifier/driver 312 to increase the drive efficiency and effectiveness. Power detection components 316 may also be included to confirm appropriate operation and calibration. For example, electric power and other energy detection components 316 may be used to monitor the amount of power going to an exemplary probe system.
  • [0038]
    Various sensing and monitoring components 304 may also be suitably implemented within control system 300. For example, in accordance with an exemplary embodiment, monitoring, sensing and interface control components 324 may be configured to operate with various motion detection systems implemented within transducer probe 204 to receive and process information such as acoustic or other spatial and temporal information from a region of interest. Sensing and monitoring components can also include various controls, interfacing and switches 309 and/or power detectors 316. Such sensing and monitoring components 304 can facilitate open-loop and/or closed-loop feedback systems within treatment system 200.
  • [0039]
    Cooling/coupling control systems 306 may be provided to remove waste heat from an exemplary probe 204, provide a controlled temperature at the superficial tissue interface and deeper into tissue, and/or provide acoustic coupling from transducer probe 204 to region-of-interest 206. Such cooling/coupling control systems 306 can also be configured to operate in both open-loop and/or closed-loop feedback arrangements with various coupling and feedback components.
  • [0040]
    Processing and control logic components 308 can comprise various system processors and digital control logic 307, such as one or more of microcontrollers, microprocessors, field-programmable gate arrays (FPGAs), computer boards, and associated components, including firmware and control software 326, which interfaces to user controls and interfacing circuits as well as input/output circuits and systems for communications, displays, interfacing, storage, documentation, and other useful functions. System software and firmware 326 controls all initialization, timing, level setting, monitoring, safety monitoring, and all other system functions required to accomplish user-defined treatment objectives. Further, various control switches 308 can also be suitably configured to control operation.
  • [0041]
    An exemplary transducer probe 204 can also be configured in various manners and comprise a number of reusable and/or disposable components and parts in various embodiments to facilitate its operation. For example, transducer probe 204 can be configured within any type of transducer probe housing or arrangement for facilitating the coupling of transducer to a tissue interface, with such housing comprising various shapes, contours and configurations. Transducer probe 204 can comprise any type of matching, such as for example, electric matching, which may be electrically switchable; multiplexer circuits and/or aperture/element selection circuits; and/or probe identification devices, to certify probe handle, electric matching, transducer usage history and calibration, such as one or more serial EEPROM (memories). Transducer probe 204 may also comprise cables and connectors; motion mechanisms, motion sensors and encoders; thermal monitoring sensors; and/or user control and status related switches, and indicators such as LEDs. For example, a motion mechanism in probe 204 may be used to controllably create multiple lesions, or sensing of probe motion itself may be used to controllably create multiple lesions and/or stop creation of lesions, e.g. for safety reasons if probe 204 is suddenly jerked or is dropped. In addition, an external motion encoder arm may be used to hold the probe during use, whereby the spatial position and attitude of probe 104 is sent to the control system to help controllably create lesions. Furthermore, other sensing functionality such as profilometers or other imaging modalities may be integrated into the probe in accordance with various exemplary embodiments.
  • [0042]
    With reference to FIGS. 4A and 4B, in accordance with an exemplary embodiment, a transducer probe 400 can comprise a control interface 402, a transducer 404, coupling components 406, and monitoring/sensing components 408, and/or motion mechanism 410. However, transducer probe 400 can be configured and optimized in a variety of ways with more or less parts and components to provide treatment of sweat glands, and the embodiments in FIGS. 4A and 4B are merely for illustration purposes.
  • [0043]
    Control interface 402 is configured for interfacing with control system 300 to facilitate control of transducer probe 400. Control interface components 402 can comprise multiplexer/aperture select 424, switchable electric matching networks 426, serial EEPROMs and/or other processing components and matching and probe usage information 430 and interface connectors 432.
  • [0044]
    Coupling components 406 can comprise various devices to facilitate coupling of transducer probe 400 to a region of interest. For example, coupling components 406 can comprise cooling and acoustic coupling system 420 configured for acoustic coupling of ultrasound energy and signals. Acoustic cooling/coupling system 420 with possible connections such as manifolds may be utilized to couple sound into the region-of-interest, control temperature at the interface and deeper into tissue, provide liquid-filled lens focusing, and/or to remove transducer waste heat. Coupling system 420 may facilitate such coupling through use of various coupling mediums, including air and other gases, water and other fluids, gels, solids, and/or any combination thereof, or any other medium that allows for signals to be transmitted between transducer active elements 412 and a region of interest. In addition to providing a coupling function, in accordance with an exemplary embodiment, coupling system 420 can also be configured for providing temperature control during the treatment application. For example, coupling system 420 can be configured for controlled cooling of an interface surface or region between transducer probe 400 and a region of interest and beyond by suitably controlling the temperature of the coupling medium. The suitable temperature for such coupling medium can be achieved in various manners, and utilize various feedback systems, such as thermocouples, thermistors or any other device or system configured for temperature measurement of a coupling medium. Such controlled cooling can be configured to further facilitate spatial and/or thermal energy control of transducer probe 400.
  • [0045]
    In accordance with an exemplary embodiment, with additional reference to FIG. 11, acoustic coupling and cooling 1140 can be provided to acoustically couple energy and imaging signals from transducer probe 1104 to and from the region of interest 1106 and deeper into tissue, to provide thermal control at the probe to region-of-interest interface 1110, and to remove potential waste heat from the transducer probe at region 1144. Temperature monitoring can be provided at the coupling interface via a thermal sensor 1146 to provide a mechanism of temperature measurement 1148 and control via control system 1102 and a thermal control system 1142. Thermal control may consist of passive cooling such as via heat sinks or natural conduction and convection or via active cooling such as with peltier thermoelectric coolers, refrigerants, or fluid-based systems comprised of pump, fluid reservoir, bubble detection, flow sensor, flow channels/tubing 1144 and thermal control 1142.
  • [0046]
    With continued reference to FIG. 4, monitoring and sensing components 408 can comprise various motion and/or position sensors 416, temperature monitoring sensors 418, user control and feedback switches 414 and other like components for facilitating control by control system 300, e.g., to facilitate spatial and/or temporal control through open-loop and closed-loop feedback arrangements that monitor various spatial and temporal characteristics.
  • [0047]
    Motion mechanism 410 can comprise manual operation, mechanical arrangements, or some combination thereof. For example, a motion mechanism 422 can be suitably controlled by control system 300, such as through the use of accelerometers, encoders or other position/orientation devices 416 to determine and enable movement and positions of transducer probe 400. Linear, rotational or variable movement can be facilitated, e.g., those depending on the treatment application and tissue contour surface.
  • [0048]
    Transducer 404 can comprise one or more transducers configured for treating of sweat glands and targeted regions. Transducer 404 can also comprise one or more transduction elements and/or lenses 412. The transduction elements can comprise a piezoelectrically active material, such as lead zirconante titanate (PZT), or any other piezoelectrically active material, such as a piezoelectric ceramic, crystal, plastic, and/or composite materials, as well as lithium niobate, lead titanate, barium titanate, and/or lead metaniobate. In addition to, or instead of, a piezoelectrically active material, transducer 404 can comprise any other materials configured for generating radiation and/or acoustical energy. Transducer 404 can also comprise one or more matching layers configured along with the transduction element such as coupled to the piezoelectrically active material. Acoustic matching layers and/or damping may be employed as necessary to achieve the desired electroacoustic response.
  • [0049]
    In accordance with an exemplary embodiment, the thickness of the transduction element of transducer 404 can be configured to be uniform. That is, a transduction element 412 can be configured to have a thickness that is substantially the same throughout. In accordance with another exemplary embodiment, the thickness of a transduction element 412 can also be configured to be variable. For example, transduction element(s) 412 of transducer 404 can be configured to have a first thickness selected to provide a center operating frequency of approximately 2 kHz to 75 MHz, such as for imaging applications. Transduction element 412 can also be configured with a second thickness selected to provide a center operating frequency of approximately 2 to 50 MHz, and typically between 2 MHz and 25 MHz for therapy application. Transducer 404 can be configured as a single broadband transducer excited with at least two or more frequencies to provide an adequate output for generating a desired response. Transducer 404 can also be configured as two or more individual transducers, wherein each transducer comprises one or more transduction element. The thickness of the transduction elements can be configured to provide center-operating frequencies in a desired treatment range.
  • [0050]
    Transducer 404 may be composed of one or more individual transducers in any combination of focused, planar, or unfocused single-element, multi-element, or array transducers, including 1-D, 2-D, and annular arrays; linear, curvilinear, sector, or spherical arrays; spherically, cylindrically, and/or electronically focused, defocused, and/or lensed sources. For example, with reference to an exemplary embodiment depicted in FIG. 5, transducer 500 can be configured as an acoustic array to facilitate phase focusing. That is, transducer 500 can be configured as an array of electronic apertures that may be operated by a variety of phases via variable electronic time delays. By the term “operated,” the electronic apertures of transducer 500 may be manipulated, driven, used, and/or configured to produce and/or deliver an energy beam corresponding to the phase variation caused by the electronic time delay. For example, these phase variations can be used to deliver defocused beams, planar beams, and/or focused beams, each of which may be used in combination to achieve different physiological effects in a region of interest 510. Transducer 500 may additionally comprise any software and/or other hardware for generating, producing and or driving a phased aperture array with one or more electronic time delays.
  • [0051]
    Transducer 500 can also be configured to provide focused treatment to one or more regions of interest using various frequencies. In order to provide focused treatment, transducer 500 can be configured with one or more variable depth devices to facilitate treatment. For example, transducer 500 may be configured with variable depth devices disclosed in U.S. patent application Ser. No. 10/944,500, entitled “System and Method for Variable Depth Ultrasound”, filed on Sep. 16, 2004, having at least one common inventor and a common Assignee as the present application, and incorporated herein by reference. In addition, transducer 500 can also be configured to treat one or more additional ROI 510 through the enabling of sub-harmonics or pulse-echo imaging, as disclosed in U.S. patent application Ser. No. 10/944,499, entitled “Method and System for Ultrasound Treatment with a Multi-directional Transducer”, filed on Sep. 16, 2004, having at least one common inventor and a common Assignee as the present application, and also incorporated herein by reference.
  • [0052]
    Moreover, any variety of mechanical lenses or variable focus lenses, e.g. liquid-filled lenses, may also be used to focus and or defocus the sound field. For example, with reference to exemplary embodiments depicted in FIGS. 6A and 6B, transducer 600 may also be configured with an electronic focusing array 604 in combination with one or more transduction elements 606 to facilitate increased flexibility in treating ROI 610. Array 604 may be configured in a manner similar to transducer 502. That is, array 604 can be configured as an array of electronic apertures that may be operated by a variety of phases via variable electronic time delays, for example, T1, T2 . . . Tj. By the term “operated,” the electronic apertures of array 604 may be manipulated, driven, used, and/or configured to produce and/or deliver energy in a manner corresponding to the phase variation caused by the electronic time delay. For example, these phase variations can be used to deliver defocused beams, planar beams, and/or focused beams, each of which may be used in combination to achieve different physiological effects in ROI 610.
  • [0053]
    Transduction elements 606 may be configured to be concave, convex, and/or planar. For example, in an exemplary embodiment depicted in FIG. 6A, transduction elements 606A are configured to be concave in order to provide focused energy for treatment of ROI 610. Additional embodiments are disclosed in U.S. patent application Ser. No. 10/944,500, entitled “Variable Depth Transducer System and Method”, and again incorporated herein by reference.
  • [0054]
    In another exemplary embodiment, depicted in FIG. 6B, transduction elements 606B can be configured to be substantially flat in order to provide substantially uniform energy to ROI 610. While FIGS. 6A and 6B depict exemplary embodiments with transduction elements 604 configured as concave and substantially flat, respectively, transduction elements 604 can be configured to be concave, convex, and/or substantially flat. In addition, transduction elements 604 can be configured to be any combination of concave, convex, and/or substantially flat structures. For example, a first transduction element can be configured to be concave, while a second transduction element can be configured to be substantially flat.
  • [0055]
    With reference to FIGS. 8A and 8B, transducer 404 can be configured as single-element arrays, wherein a single-element 802, e.g., a transduction element of various structures and materials, can be configured with a plurality of masks 804, such masks comprising ceramic, metal or any other material or structure for masking or altering energy distribution from element 802, creating an array of energy distributions 808. Masks 804 can be coupled directly to element 802 or separated by a standoff 806, such as any suitably solid or liquid material.
  • [0056]
    An exemplary transducer 404 can also be configured as an annular array to provide planar, focused and/or defocused acoustical energy. For example, with reference to FIGS. 10A and 10B, in accordance with an exemplary embodiment, an annular array 1000 can comprise a plurality of rings 1012, 1014, 1016 to N. Rings 1012, 1014, 1016 to N can be mechanically and electrically isolated into a set of individual elements, and can create planar, focused, or defocused waves. For example, such waves can be centered on-axis, such as by methods of adjusting corresponding transmit and/or receive delays, τ1, τ2, τ3 . . . τN. An electronic focus can be suitably moved along various depth positions, and can enable variable strength or beam tightness, while an electronic defocus can have varying amounts of defocusing. In accordance with an exemplary embodiment, a lens and/or convex or concave shaped annular array 1000 can also be provided to aid focusing or defocusing such that any time differential delays can be reduced. Movement of annular array 800 in one, two or three-dimensions, or along any path, such as through use of probes and/or any conventional robotic arm mechanisms, may be implemented to scan and/or treat a volume or any corresponding space within a region of interest.
  • [0057]
    Transducer 404 can also be configured in other annular or non-array configurations for imaging/therapy functions. For example, with reference to FIGS. 10C-10F, a transducer can comprise an imaging element 1012 configured with therapy element(s) 1014. Elements 1012 and 1014 can comprise a single-transduction element, e.g., a combined imaging/transducer element, or separate elements, can be electrically isolated 1022 within the same transduction element or between separate imaging and therapy elements, and/or can comprise standoff 1024 or other matching layers, or any combination thereof. For example, with particular reference to FIG. 10F, a transducer can comprise an imaging element 1012 having a surface 1028 configured for focusing, defocusing or planar energy distribution, with therapy elements 1014 including a stepped-configuration lens configured for focusing, defocusing, or planar energy distribution.
  • [0058]
    In accordance with various exemplary embodiments of the present invention, transducer 404 may be configured to provide one, two and/or three-dimensional treatment applications for focusing acoustic energy to one or more regions of interest. For example, as discussed above, transducer 404 can be suitably diced to form a one-dimensional array, e.g., transducer 602 comprising a single array of sub-transduction elements.
  • [0059]
    In accordance with another exemplary embodiment, transducer 404 may be suitably diced in two-dimensions to form a two-dimensional array. For example, with reference to FIG. 9, an exemplary two-dimensional array 900 can be suitably diced into a plurality of two-dimensional portions 902. Two-dimensional portions 902 can be suitably configured to focus on the treatment region at a certain depth, and thus provide respective slices 904 of the treatment region. As a result, the two-dimensional array 900 can provide a two-dimensional slicing of the image place of a treatment region, thus providing two-dimensional treatment.
  • [0060]
    In accordance with another exemplary embodiment, transducer 404 may be suitably configured to provide three-dimensional treatment. For example, to provide-three dimensional treatment of a region of interest, with reference again to FIG. 1, a three-dimensional system can comprise a transducer within probe 104 configured with an adaptive algorithm, such as, for example, one utilizing three-dimensional graphic software, contained in a control system, such as control system 102. The adaptive algorithm is suitably configured to receive two-dimensional imaging, temperature and/or treatment or other tissue parameter information relating to the region of interest, process the received information, and then provide corresponding three-dimensional imaging, temperature and/or treatment information.
  • [0061]
    In accordance with an exemplary embodiment, with reference again to FIG. 9, an exemplary three-dimensional system can comprise a two-dimensional array 900 configured with an adaptive algorithm to suitably receive 904 slices from different image planes of the treatment region, process the received information, and then provide volumetric information 906, e.g., three-dimensional imaging, temperature and/or treatment information. Moreover, after processing the received information with the adaptive algorithm, the two-dimensional array 900 may suitably provide therapeutic heating to the volumetric region 906 as desired.
  • [0062]
    In accordance with other exemplary embodiments, rather than utilizing an adaptive algorithm, such as three-dimensional software, to provide three-dimensional imaging and/or temperature information, an exemplary three-dimensional system can comprise a single transducer 404 configured within a probe arrangement to operate from various rotational and/or translational positions relative to a target region.
  • [0063]
    To further illustrate the various structures for transducer 404, with reference to FIG. 7, ultrasound therapy transducer 700 can be configured for a single focus, an array of foci, a locus of foci, a line focus, and/or diffraction patterns. Transducer 700 can also comprise single elements, multiple elements, annular arrays, one-, two-, or three-dimensional arrays, broadband transducers, and/or combinations thereof, with or without lenses, acoustic components, and mechanical and/or electronic focusing. Transducers configured as spherically focused single elements 702, annular arrays 704, annular arrays with damped regions 706, line focused single elements 708, 1-D linear arrays 710, 1-D curvilinear arrays in concave or convex form, with or without elevation focusing, 2-D arrays, and 3-D spatial arrangements of transducers may be used to perform therapy and/or imaging and acoustic monitoring functions. For any transducer configuration, focusing and/or defocusing may be in one plane or two planes via mechanical focus 720, convex lens 722, concave lens 724, compound or multiple lenses 726, planar form 728, or stepped form, such as illustrated in FIG. 10F. Any transducer or combination of transducers may be utilized for treatment. For example, an annular transducer may be used with an outer portion dedicated to therapy and the inner disk dedicated to broadband imaging wherein such imaging transducer and therapy transducer have different acoustic lenses and design, such as illustrated in FIG. 10C-10F.
  • [0064]
    Moreover, such transduction elements 700 may comprise a piezoelectrically active material, such as lead zirconante titanate (PZT), or any other piezoelectrically active material, such as a piezoelectric ceramic, crystal, plastic, and/or composite materials, as well as lithium niobate, lead titanate, barium titanate, and/or lead metaniobate. Transduction elements 700 may also comprise one or more matching layers configured along with the piezoelectrically active material. In addition to or instead of piezoelectrically active material, transduction elements 700 can comprise any other materials configured for generating radiation and/or acoustical energy. A means of transferring energy to and from the transducer to the region of interest is provided.
  • [0065]
    In accordance with another exemplary embodiment, with reference to FIG. 12, an exemplary treatment system 200 can be configured with and/or combined with various auxiliary systems to provide additional functions. For example, an exemplary treatment system 1200 for treatment of sweat glands can further comprise an auxiliary imaging modality 1272 and/or auxiliary monitoring modality 1274 may be based upon at least one of photography and other visual optical methods, magnetic resonance imaging (MRI), computed tomography (CT), optical coherence tomography (OCT), electromagnetic, microwave, or radio frequency (RF) methods, positron emission tomography (PET), infrared, ultrasound, acoustic, or any other suitable method of visualization, localization, or monitoring of the region-of-interest, including imaging/monitoring enhancements. Such imaging/monitoring enhancement for ultrasound imaging via probe 1204 and control system 1202 can comprise M-mode, persistence, filtering, color, Doppler, and harmonic imaging among others; furthermore an ultrasound treatment system 1270, as a primary source of treatment, may be combined with a secondary source of treatment 1276, including radio frequency (RF), intense pulsed light (IPL), laser, infrared laser, microwave, or any other suitable energy source.
  • [0066]
    In accordance with another exemplary embodiment, with reference to FIG. 13, treatment composed of imaging, monitoring, and/or therapy to a region of interest 1302 and/or 1308 may be aided, augmented, and/or delivered with passive or active devices 1304 and/or 1306 within the oral and/or nasal cavity, respectively. For example, if passive or active device 1304 and/or 1306 are second transducers or acoustic reflectors acoustically coupled to the mucous membranes it is possible to obtain through transmission, tomographic, or round-trip acoustic waves which are useful for treatment monitoring, such as in measuring acoustic speed of sound and attenuation, which are temperature dependent; furthermore such transducers could be used to treat and/or image. In addition an active, passive, or active/passive object 1304 and/or 1306 may be used to flatten the skin, and/or may be used as an imaging grid, marker, or beacon, to aid determination of position. A passive or active device 1304 and/or 1306 may also be used to aid cooling or temperature control. Natural air in the oral cavity and/or nasal cavity may also be used as passive device 1304 and/or 1306 whereby it may be utilized to as an acoustic reflector to aid thickness measurement and monitoring function.
  • [0067]
    The present invention may be described herein in terms of various functional components and processing steps. It should be appreciated that such components and steps may be realized by any number of hardware components configured to perform the specified functions. For example, the present invention may employ various medical treatment devices, visual imaging and display devices, input terminals and the like, which may carry out a variety of functions under the control of one or more control systems or other control devices. In addition, the present invention may be practiced in any number of medical contexts and that the exemplary embodiments relating to a system as described herein are merely indicative of exemplary applications for the invention. For example, the principles, features and methods discussed may be applied to any medical application. Further, various aspects of the present invention may be suitably applied to other applications, such as other medical or industrial applications.

Claims (22)

  1. 1. An ultrasound treatment system configured for treatment of sweat glands, said ultrasound treatment system comprising:
    a control system for facilitating control of the ultrasound treatment system; and
    a probe system configured for targeted delivery of ultrasound energy to produce a treatment region for destroying said sweat gland.
  2. 2. The ultrasound treatment system according to claim 1, wherein said probe system is configured for destroying the sweat gland within a specified treatment depth identified through localization of said sweat gland.
  3. 3. The ultrasound treatment system according to claim 1, wherein said spatially defined patterns comprise a discrete locus of spaced lesions comprising at least one of cross-stitch, cigar-shaped, ellipsoidal, mushroom-shaped and wedge-shaped lesions.
  4. 4. The ultrasound treatment system of claim 1, wherein said control system comprises an imaging system configured for monitoring of said treatment region prior to, during and after delivery of ultrasound energy into said sweat gland.
  5. 5. The ultrasound treatment system of claim 4, wherein said imaging system is configured to provide feedback to facilitate said targeted delivery.
  6. 6. The ultrasound treatment system according to claim 1, wherein said display system comprises a display of images corresponding to a temperature profile of said treatment region.
  7. 7. The ultrasound treatment system according to claim 1, wherein said probe system comprises an imaging and therapy transducer configured for targeted delivery of ablative ultrasound within said sweat gland.
  8. 8. The ultrasound treatment system according to claim 7, wherein said imaging and therapy transducer comprise a combined transducer within an electronic array of transduction elements.
  9. 9. The ultrasound treatment system according to claim 7, wherein said imaging and therapy transducer comprises a single element array comprising a single transduction element and a plurality of masks configured for generating a plurality of ablative zones with each of said plurality of ablative zones providing at least one of focused, defocused and planar ultrasound energy distribution.
  10. 10. The ultrasound treatment system according to claim 1, wherein said probe is configured for targeted delivery of ultrasound energy through adjustable control of spatial parameters and temporal parameters of said probe to generate conformal lesions of specifically targeted shapes, sizes and orientations.
  11. 11. The ultrasound treatment system according to claim 1, wherein said treatment system comprises an imaging, therapy, and treatment monitoring system combined with auxiliary imaging and treatment monitoring apparatus and secondary therapy systems, and wherein said auxiliary imaging apparatus comprises at least one of a photographic instrument and an optical modality.
  12. 12. The ultrasound treatment system according to claim 1, wherein said control system comprises an imaging system configured for facilitating at least one of one-dimensional, two-dimensional and three-dimensional imaging or therapy.
  13. 13. A method for providing treatment of acne and sweat glands, said method comprising:
    localizing of at least one targeted region within a region of interest, said localizing configured for identifying at least one sweat gland;
    targeting of delivery of ablative ultrasound energy from a transducer probe to said at least one sweat gland; and
    monitoring of results of said targeted delivery within said at least one sweat gland during and after said targeted delivery to continue planning of treatment.
  14. 14. The method of claim 13, wherein said localizing comprises imaging a region of interest to identify said at least one sweat gland.
  15. 15. The method of claim 13, said targeting of delivery of ultrasound energy comprises destroying said sweat gland within a specified treatment depth identified through localization of said sweat gland.
  16. 16. The method of claim 13, wherein said targeting of delivery comprises adjustable control of spatial parameters and temporal parameters of said transducer probe to generate conformal lesions of specifically targeted shapes, sizes and orientations.
  17. 17. The method of claim 13, wherein said monitoring of results comprises measurement of results of treatment of said at least one sweat gland as visualized during and after said target delivery of ablative ultrasound.
  18. 18. The method of claim 13, wherein said monitoring comprises monitoring the temperature profile of said targeted region.
  19. 19. The method of claim 13, wherein said targeted delivery comprises producing of a matrix of spaced treatment spots comprising at least one of two-dimensional and three-dimensional matrix of lesions along a scanned pattern created by scanning of said transducer probe.
  20. 20. The method according to claim 19, wherein producing said spatially defined patterns comprises producing a discrete locus of spaced conformal lesions based on control of spatial and temporal parameters.
  21. 21. The method according to claim 13, wherein said localizing comprises generating three-dimensional imaging information and said targeting comprises treating three-dimensional treatment region.
  22. 22. The method according to claim 13, wherein said targeting of delivery further comprises cooling through any tissue regions between and including skin and said at least one sweat gland to facilitate treatment.
US11163152 2004-10-13 2005-10-06 Method and system for treatment of sweat glands Abandoned US20060111744A1 (en)

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US61775204 true 2004-10-13 2004-10-13
US11163152 US20060111744A1 (en) 2004-10-13 2005-10-06 Method and system for treatment of sweat glands

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US11163152 US20060111744A1 (en) 2004-10-13 2005-10-06 Method and system for treatment of sweat glands
US13444485 US8282554B2 (en) 2004-10-06 2012-04-11 Methods for treatment of sweat glands
US13603279 US8523775B2 (en) 2004-10-06 2012-09-04 Energy based hyperhidrosis treatment
US13603159 US8333700B1 (en) 2004-10-06 2012-09-04 Methods for treatment of hyperhidrosis
US13950728 US8932224B2 (en) 2004-10-06 2013-07-25 Energy based hyperhidrosis treatment
US14571835 US9421029B2 (en) 2004-10-06 2014-12-16 Energy based hyperhidrosis treatment
US15243081 US20160354618A1 (en) 2004-10-06 2016-08-22 Energy based hyperhidrosis treatment

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US11163152 Abandoned US20060111744A1 (en) 2004-10-13 2005-10-06 Method and system for treatment of sweat glands
US13444485 Active US8282554B2 (en) 2004-10-06 2012-04-11 Methods for treatment of sweat glands
US13603279 Active US8523775B2 (en) 2004-10-06 2012-09-04 Energy based hyperhidrosis treatment
US13603159 Active US8333700B1 (en) 2004-10-06 2012-09-04 Methods for treatment of hyperhidrosis
US13950728 Active US8932224B2 (en) 2004-10-06 2013-07-25 Energy based hyperhidrosis treatment
US14571835 Active 2025-11-23 US9421029B2 (en) 2004-10-06 2014-12-16 Energy based hyperhidrosis treatment
US15243081 Pending US20160354618A1 (en) 2004-10-06 2016-08-22 Energy based hyperhidrosis treatment

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US13603279 Active US8523775B2 (en) 2004-10-06 2012-09-04 Energy based hyperhidrosis treatment
US13603159 Active US8333700B1 (en) 2004-10-06 2012-09-04 Methods for treatment of hyperhidrosis
US13950728 Active US8932224B2 (en) 2004-10-06 2013-07-25 Energy based hyperhidrosis treatment
US14571835 Active 2025-11-23 US9421029B2 (en) 2004-10-06 2014-12-16 Energy based hyperhidrosis treatment
US15243081 Pending US20160354618A1 (en) 2004-10-06 2016-08-22 Energy based hyperhidrosis treatment

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Cited By (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060089632A1 (en) * 2004-10-06 2006-04-27 Guided Therapy Systems, L.L.C. Method and system for treating acne and sebaceous glands
US20070213705A1 (en) * 2006-03-08 2007-09-13 Schmid Peter M Insulated needle and system
US20080021353A1 (en) * 2005-12-30 2008-01-24 Manfred Menzi Acoustic pressure wave applicator system with conduction pad
US20080139974A1 (en) * 2006-12-04 2008-06-12 Da Silva Luiz B Devices and Methods for Treatment of Skin Conditions
US20090062724A1 (en) * 2007-08-31 2009-03-05 Rixen Chen System and apparatus for sonodynamic therapy
US20090093737A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Ultrasound apparatus with treatment lens
WO2008131302A3 (en) * 2007-04-19 2009-12-30 The Foundry, Inc. Methods and apparatus for reducing sweat production
US7758524B2 (en) 2004-10-06 2010-07-20 Guided Therapy Systems, L.L.C. Method and system for ultra-high frequency ultrasound treatment
US20100222852A1 (en) * 2009-02-24 2010-09-02 Vasily David B Apparatus and Method for Decolonizing Microbes on the Surfaces of the Skin and In Body Cavities
US7824348B2 (en) 2004-09-16 2010-11-02 Guided Therapy Systems, L.L.C. System and method for variable depth ultrasound treatment
US20110196365A1 (en) * 2008-10-22 2011-08-11 Miramar Labs, Inc. Systems, Apparatus, Methods, and Procedures for the Non-Invasive Treatment of Tissue Using Microwave Energy
US20110201976A1 (en) * 2005-06-01 2011-08-18 Focus Surgery, Inc. Laparoscopic hifu probe
US8073550B1 (en) 1997-07-31 2011-12-06 Miramar Labs, Inc. Method and apparatus for treating subcutaneous histological features
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
US8166332B2 (en) 2005-04-25 2012-04-24 Ardent Sound, Inc. Treatment system for enhancing safety of computer peripheral for use with medical devices by isolating host AC power
US20120165668A1 (en) * 2010-08-02 2012-06-28 Guided Therapy Systems, Llc Systems and methods for treating acute and/or chronic injuries in soft tissue
US8235909B2 (en) 2004-05-12 2012-08-07 Guided Therapy Systems, L.L.C. Method and system for controlled scanning, imaging and/or therapy
US8282554B2 (en) 2004-10-06 2012-10-09 Guided Therapy Systems, Llc Methods for treatment of sweat glands
US8401668B2 (en) 2007-04-19 2013-03-19 Miramar Labs, Inc. Systems and methods for creating an effect using microwave energy to specified tissue
US8406894B2 (en) 2007-12-12 2013-03-26 Miramar Labs, Inc. Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
US8409097B2 (en) 2000-12-28 2013-04-02 Ardent Sound, Inc Visual imaging system for ultrasonic probe
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US20130123625A1 (en) * 2011-11-14 2013-05-16 Boston Scientific Scimed, Inc. Integrated ultrasound ablation and imaging device and related methods
US8444562B2 (en) 2004-10-06 2013-05-21 Guided Therapy Systems, Llc System and method for treating muscle, tendon, ligament and cartilage tissue
US8469951B2 (en) 2011-08-01 2013-06-25 Miramar Labs, Inc. Applicator and tissue interface module for dermatological device
US8480585B2 (en) 1997-10-14 2013-07-09 Guided Therapy Systems, Llc Imaging, therapy and temperature monitoring ultrasonic system and method
JP2013176628A (en) * 2007-04-19 2013-09-09 Miramar Labs Inc Method and apparatus for reducing sweat production
US8535228B2 (en) 2004-10-06 2013-09-17 Guided Therapy Systems, Llc Method and system for noninvasive face lifts and deep tissue tightening
US8574251B2 (en) 2005-09-07 2013-11-05 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
DE102012209008A1 (en) * 2012-05-29 2013-12-05 Wellcomet Gmbh Device for generation of e.g. radio frequency current for pressurization of human tissue with frequency current, has motion sensor cooperating with control unit such that intensity of wave is controlled depending on measurement signals
US8663112B2 (en) 2004-10-06 2014-03-04 Guided Therapy Systems, Llc Methods and systems for fat reduction and/or cellulite treatment
US8688228B2 (en) 2007-04-19 2014-04-01 Miramar Labs, Inc. Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
US8690778B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Energy-based tissue tightening
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
US8764687B2 (en) 2007-05-07 2014-07-01 Guided Therapy Systems, Llc Methods and systems for coupling and focusing acoustic energy using a coupler member
US8852103B2 (en) 2011-10-17 2014-10-07 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US8858471B2 (en) 2011-07-10 2014-10-14 Guided Therapy Systems, Llc Methods and systems for ultrasound treatment
US8857438B2 (en) 2010-11-08 2014-10-14 Ulthera, Inc. Devices and methods for acoustic shielding
US8915870B2 (en) 2004-10-06 2014-12-23 Guided Therapy Systems, Llc Method and system for treating stretch marks
US9011336B2 (en) 2004-09-16 2015-04-21 Guided Therapy Systems, Llc Method and system for combined energy therapy profile
US9011337B2 (en) 2011-07-11 2015-04-21 Guided Therapy Systems, Llc Systems and methods for monitoring and controlling ultrasound power output and stability
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9114247B2 (en) 2004-09-16 2015-08-25 Guided Therapy Systems, Llc Method and system for ultrasound treatment with a multi-directional transducer
US9216276B2 (en) 2007-05-07 2015-12-22 Guided Therapy Systems, Llc Methods and systems for modulating medicants using acoustic energy
US9241683B2 (en) 2006-10-04 2016-01-26 Ardent Sound Inc. Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid
US9241763B2 (en) 2007-04-19 2016-01-26 Miramar Labs, Inc. Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US9263663B2 (en) 2012-04-13 2016-02-16 Ardent Sound, Inc. Method of making thick film transducer arrays
US9272124B2 (en) 2005-12-02 2016-03-01 Ulthera, Inc. Systems and devices for selective cell lysis and methods of using same
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9504446B2 (en) 2010-08-02 2016-11-29 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
US9510802B2 (en) 2012-09-21 2016-12-06 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
US9566454B2 (en) 2006-09-18 2017-02-14 Guided Therapy Systems, Llc Method and sysem for non-ablative acne treatment and prevention
US9667889B2 (en) 2013-04-03 2017-05-30 Butterfly Network, Inc. Portable electronic devices with integrated imaging capabilities
US9694212B2 (en) 2004-10-06 2017-07-04 Guided Therapy Systems, Llc Method and system for ultrasound treatment of skin
US9827449B2 (en) 2004-10-06 2017-11-28 Guided Therapy Systems, L.L.C. Systems for treating skin laxity

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2621521T3 (en) * 2002-03-15 2017-07-04 The General Hospital Corporation Method for selective breakdown of fatty tissue by controlled cooling
JP2007516809A (en) * 2003-12-30 2007-06-28 ライポソニックス, インコーポレイテッド Ultrasonic transducer component
US8926533B2 (en) * 2003-12-30 2015-01-06 Liposonix, Inc. Therapy head for use with an ultrasound system
US20110077559A1 (en) * 2003-12-30 2011-03-31 Medicis Technologies Corporation Ultrasound therapy head with movement control
US7530356B2 (en) * 2004-10-06 2009-05-12 Guided Therapy Systems, Inc. Method and system for noninvasive mastopexy
US8920320B2 (en) * 2006-03-10 2014-12-30 Liposonix, Inc. Methods and apparatus for coupling a HIFU transducer to a skin surface
US9132031B2 (en) 2006-09-26 2015-09-15 Zeltiq Aesthetics, Inc. Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
US8523927B2 (en) 2007-07-13 2013-09-03 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
JP5474791B2 (en) 2007-08-21 2014-04-16 ゼルティック エステティックス インコーポレイテッド Monitoring the cooling subcutaneous lipid-rich cells, such as cooling of adipose tissue
US20090248578A1 (en) * 2008-03-20 2009-10-01 Liposonix, Inc. Methods and apparatus for medical device investment recovery
US8603073B2 (en) 2008-12-17 2013-12-10 Zeltiq Aesthetics, Inc. Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells
CN102548615A (en) * 2009-03-04 2012-07-04 利普索尼克斯股份有限公司 Ultrasonic treatment of adipose tissue at multiple depths
EP2990079B1 (en) * 2009-03-23 2017-05-03 LipoSonix, Inc. Method of determining functionality of an ultrasound therapy head
KR20170084347A (en) 2009-04-30 2017-07-19 젤티크 애스세틱스, 인코포레이티드. Device, system and method of removing heat from subcutaneous lipid-rich cells
US8932238B2 (en) * 2009-09-29 2015-01-13 Liposonix, Inc. Medical ultrasound device with liquid dispensing device coupled to a therapy head
US9314368B2 (en) 2010-01-25 2016-04-19 Zeltiq Aesthetics, Inc. Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associates devices, systems and methods
US20110196438A1 (en) * 2010-02-10 2011-08-11 Lukas Mnozil Therapy device and method for treating underlying tissue using electrical and acoustic energies
US8573392B2 (en) 2010-09-22 2013-11-05 Liposonix, Inc. Modified atmosphere packaging for ultrasound transducer cartridge
WO2014014965A1 (en) * 2012-07-16 2014-01-23 Mirabilis Medica, Inc. Human interface and device for ultrasound guided treatment
US20140207213A1 (en) * 2013-01-23 2014-07-24 Khalilullah A. Khatri Laser method for treating hyperhidrosis targeting sweat glands
US20140221877A1 (en) * 2013-02-01 2014-08-07 Moshe Ein-Gal Pressure-assisted irreversible electroporation
US9545523B2 (en) 2013-03-14 2017-01-17 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue
US20140276053A1 (en) * 2013-03-14 2014-09-18 SonaCare Medical, LLC Multi-element therapy and imaging transducer for ultrasound therapy
US9844460B2 (en) 2013-03-14 2017-12-19 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
WO2015117001A1 (en) 2014-01-31 2015-08-06 Zeltiq Aesthetics, Inc. Compositions, treatment systems and methods for improved cooling of lipid-rich tissue
USD777338S1 (en) 2014-03-20 2017-01-24 Zeltiq Aesthetics, Inc. Cryotherapy applicator for cooling tissue
WO2017139713A1 (en) * 2016-02-12 2017-08-17 Sciton, Inc. Devices for image-guided light treatment of skin

Citations (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3913386A (en) * 1973-01-16 1975-10-21 Commissariat Energie Atomique Method of compensation for the angle of refraction of an ultrasonic beam and a device for the application of said method
US3965455A (en) * 1974-04-25 1976-06-22 The United States Of America As Represented By The Secretary Of The Navy Focused arc beam transducer-reflector
US3992925A (en) * 1973-12-10 1976-11-23 U.S. Philips Corporation Device for ultrasonic scanning
US4039312A (en) * 1972-07-04 1977-08-02 Marcel Joseph Gaston Patru Bacteriostatic, fungistatic and algicidal compositions, particularly for submarine paints
US4059098A (en) * 1975-07-21 1977-11-22 Stanford Research Institute Flexible ultrasound coupling system
US4101795A (en) * 1976-10-25 1978-07-18 Matsushita Electric Industrial Company Ultrasonic probe
US4213344A (en) * 1978-10-16 1980-07-22 Krautkramer-Branson, Incorporated Method and apparatus for providing dynamic focussing and beam steering in an ultrasonic apparatus
US4276491A (en) * 1979-10-02 1981-06-30 Ausonics Pty. Limited Focusing piezoelectric ultrasonic medical diagnostic system
US4315514A (en) * 1980-05-08 1982-02-16 William Drewes Method and apparatus for selective cell destruction
US4325381A (en) * 1979-11-21 1982-04-20 New York Institute Of Technology Ultrasonic scanning head with reduced geometrical distortion
US4343301A (en) * 1979-10-04 1982-08-10 Robert Indech Subcutaneous neural stimulation or local tissue destruction
US4381007A (en) * 1981-04-30 1983-04-26 The United States Of America As Represented By The United States Department Of Energy Multipolar corneal-shaping electrode with flexible removable skirt
US4381787A (en) * 1980-08-15 1983-05-03 Technicare Corporation Ultrasound imaging system combining static B-scan and real-time sector scanning capability
US4397314A (en) * 1981-08-03 1983-08-09 Clini-Therm Corporation Method and apparatus for controlling and optimizing the heating pattern for a hyperthermia system
US4409839A (en) * 1981-07-01 1983-10-18 Siemens Ag Ultrasound camera
US4441486A (en) * 1981-10-27 1984-04-10 Board Of Trustees Of Leland Stanford Jr. University Hyperthermia system
US4452084A (en) * 1982-10-25 1984-06-05 Sri International Inherent delay line ultrasonic transducer and systems
US4484569A (en) * 1981-03-13 1984-11-27 Riverside Research Institute Ultrasonic diagnostic and therapeutic transducer assembly and method for using
US4513749A (en) * 1982-11-18 1985-04-30 Board Of Trustees Of Leland Stanford University Three-dimensional temperature probe
US4527550A (en) * 1983-01-28 1985-07-09 The United States Of America As Represented By The Department Of Health And Human Services Helical coil for diathermy apparatus
US4528979A (en) * 1982-03-18 1985-07-16 Kievsky Nauchno-Issledovatelsky Institut Otolaringologii Imeni Professora A.S. Kolomiiobenka Cryo-ultrasonic surgical instrument
US4567895A (en) * 1984-04-02 1986-02-04 Advanced Technology Laboratories, Inc. Fully wetted mechanical ultrasound scanhead
US4586512A (en) * 1981-06-26 1986-05-06 Thomson-Csf Device for localized heating of biological tissues
US4601296A (en) * 1983-10-07 1986-07-22 Yeda Research And Development Co., Ltd. Hyperthermia apparatus
US4646756A (en) * 1982-10-26 1987-03-03 The University Of Aberdeen Ultra sound hyperthermia device
US4663358A (en) * 1985-05-01 1987-05-05 Biomaterials Universe, Inc. Porous and transparent poly(vinyl alcohol) gel and method of manufacturing the same
US4668516A (en) * 1983-03-30 1987-05-26 Alain Duraffourd Composition for regenerating the collagen of connective skin tissue and a process for its preparation
US4697588A (en) * 1984-12-27 1987-10-06 Siemens Aktiengesellschaft Shock wave tube for the fragmentation of concrements
US4757820A (en) * 1985-03-15 1988-07-19 Kabushiki Kaisha Toshiba Ultrasound therapy system
US4807633A (en) * 1986-05-21 1989-02-28 Indianapolis Center For Advanced Research Non-invasive tissue thermometry system and method
US4858613A (en) * 1988-03-02 1989-08-22 Laboratory Equipment, Corp. Localization and therapy system for treatment of spatially oriented focal disease
US4860732A (en) * 1987-11-25 1989-08-29 Olympus Optical Co., Ltd. Endoscope apparatus provided with endoscope insertion aid
US4865041A (en) * 1987-02-04 1989-09-12 Siemens Aktiengesellschaft Lithotripter having an ultrasound locating system integrated therewith
US4865042A (en) * 1985-08-16 1989-09-12 Hitachi, Ltd. Ultrasonic irradiation system
US4867169A (en) * 1986-07-29 1989-09-19 Kaoru Machida Attachment attached to ultrasound probe for clinical application
US4874562A (en) * 1986-02-13 1989-10-17 Biomaterials Universe, Inc. Method of molding a polyvinyl alcohol contact lens
US4875487A (en) * 1986-05-02 1989-10-24 Varian Associates, Inc. Compressional wave hyperthermia treating method and apparatus
US4893624A (en) * 1988-06-21 1990-01-16 Massachusetts Institute Of Technology Diffuse focus ultrasound hyperthermia system
US4917096A (en) * 1987-11-25 1990-04-17 Laboratory Equipment, Corp. Portable ultrasonic probe
US4938216A (en) * 1988-06-21 1990-07-03 Massachusetts Institute Of Technology Mechanically scanned line-focus ultrasound hyperthermia system
US4938217A (en) * 1988-06-21 1990-07-03 Massachusetts Institute Of Technology Electronically-controlled variable focus ultrasound hyperthermia system
US4947046A (en) * 1988-05-27 1990-08-07 Konica Corporation Method for preparation of radiographic image conversion panel and radiographic image conversion panel thereby
US4951653A (en) * 1988-03-02 1990-08-28 Laboratory Equipment, Corp. Ultrasound brain lesioning system
US4955365A (en) * 1988-03-02 1990-09-11 Laboratory Equipment, Corp. Localization and therapy system for treatment of spatially oriented focal disease
US4958626A (en) * 1986-04-22 1990-09-25 Nippon Oil Co., Ltd. Method for applying electromagnetic wave and ultrasonic wave therapies
US4973096A (en) * 1989-08-21 1990-11-27 Joyce Patrick H Shoe transporting device
US4976709A (en) * 1988-12-15 1990-12-11 Sand Bruce J Method for collagen treatment
US4979501A (en) * 1987-05-19 1990-12-25 Vissh Voennomedicinski Institut Method and apparatus for medical treatment of the pathological state of bones
US5012797A (en) * 1990-01-08 1991-05-07 Montefiore Hospital Association Of Western Pennsylvania Method for removing skin wrinkles
US5036855A (en) * 1988-03-02 1991-08-06 Laboratory Equipment, Corp. Localization and therapy system for treatment of spatially oriented focal disease
US5054470A (en) * 1988-03-02 1991-10-08 Laboratory Equipment, Corp. Ultrasonic treatment transducer with pressurized acoustic coupling
US5115814A (en) * 1989-08-18 1992-05-26 Intertherapy, Inc. Intravascular ultrasonic imaging probe and methods of using same
US5117832A (en) * 1990-09-21 1992-06-02 Diasonics, Inc. Curved rectangular/elliptical transducer
US5123418A (en) * 1989-02-28 1992-06-23 Centre National De La Recherche Scientifique-C.N.R.S Micro-echographic probe for ultrasound collimation through a deformable surface
US5143074A (en) * 1983-12-14 1992-09-01 Edap International Ultrasonic treatment device using a focussing and oscillating piezoelectric element
US5143063A (en) * 1988-02-09 1992-09-01 Fellner Donald G Method of removing adipose tissue from the body
US5150711A (en) * 1983-12-14 1992-09-29 Edap International, S.A. Ultra-high-speed extracorporeal ultrasound hyperthermia treatment device
US5150714A (en) * 1991-05-10 1992-09-29 Sri International Ultrasonic inspection method and apparatus with audible output
US5156144A (en) * 1989-10-20 1992-10-20 Olympus Optical Co., Ltd. Ultrasonic wave therapeutic device
US5158536A (en) * 1989-08-28 1992-10-27 Biopulmonics, Inc. Lung cancer hyperthermia via ultrasound and/or convection with perfiuorochemical liquids
US5163421A (en) * 1988-01-22 1992-11-17 Angiosonics, Inc. In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging
US5191880A (en) * 1990-07-31 1993-03-09 Mcleod Kenneth J Method for the promotion of growth, ingrowth and healing of bone tissue and the prevention of osteopenia by mechanical loading of the bone tissue
US5209720A (en) * 1989-12-22 1993-05-11 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
US5224467A (en) * 1991-10-30 1993-07-06 Kabushiki Kaisha Machida Seisakusho Endoscope with direction indication mechanism
US5230334A (en) * 1992-01-22 1993-07-27 Summit Technology, Inc. Method and apparatus for generating localized hyperthermia
US5230338A (en) * 1987-11-10 1993-07-27 Allen George S Interactive image-guided surgical system for displaying images corresponding to the placement of a surgical tool or the like
US5265614A (en) * 1988-08-30 1993-11-30 Fujitsu Limited Acoustic coupler
US5267985A (en) * 1993-02-11 1993-12-07 Trancell, Inc. Drug delivery by multiple frequency phonophoresis
US5269297A (en) * 1992-02-27 1993-12-14 Angiosonics Inc. Ultrasonic transmission apparatus
US5282797A (en) * 1989-05-30 1994-02-01 Cyrus Chess Method for treating cutaneous vascular lesions
US5295484A (en) * 1992-05-19 1994-03-22 Arizona Board Of Regents For And On Behalf Of The University Of Arizona Apparatus and method for intra-cardiac ablation of arrhythmias
US5304169A (en) * 1985-09-27 1994-04-19 Laser Biotech, Inc. Method for collagen shrinkage
US5321520A (en) * 1992-07-20 1994-06-14 Automated Medical Access Corporation Automated high definition/resolution image storage, retrieval and transmission system
US5360268A (en) * 1992-11-02 1994-11-01 Nippon Soken Inc. Ultrasonic temperature measuring apparatus
US5370121A (en) * 1992-09-07 1994-12-06 Siemens Aktiengesellschaft Method and apparatus for non-invasive measurement of a temperature change in a subject
US5371483A (en) * 1993-12-20 1994-12-06 Bhardwaj; Mahesh C. High intensity guided ultrasound source
US5380280A (en) * 1993-11-12 1995-01-10 Peterson; Erik W. Aspiration system having pressure-controlled and flow-controlled modes
US5419327A (en) * 1992-12-07 1995-05-30 Siemens Aktiengesellschaft Acoustic therapy means
US5435311A (en) * 1989-06-27 1995-07-25 Hitachi, Ltd. Ultrasound therapeutic system
US5458596A (en) * 1994-05-06 1995-10-17 Dorsal Orthopedic Corporation Method and apparatus for controlled contraction of soft tissue
US5460595A (en) * 1993-06-01 1995-10-24 Dynatronics Laser Corporation Multi-frequency ultrasound therapy systems and methods
US5471488A (en) * 1994-04-05 1995-11-28 International Business Machines Corporation Clock fault detection circuit
US5487388A (en) * 1994-11-01 1996-01-30 Interspec. Inc. Three dimensional ultrasonic scanning devices and techniques
US5492126A (en) * 1994-05-02 1996-02-20 Focal Surgery Probe for medical imaging and therapy using ultrasound
US5496256A (en) * 1994-06-09 1996-03-05 Sonex International Corporation Ultrasonic bone healing device for dental application
US5501655A (en) * 1992-03-31 1996-03-26 Massachusetts Institute Of Technology Apparatus and method for acoustic heat generation and hyperthermia
US5503320A (en) * 1993-08-19 1996-04-02 United States Surgical Corporation Surgical apparatus with indicator
US5507790A (en) * 1994-03-21 1996-04-16 Weiss; William V. Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism
US5520188A (en) * 1994-11-02 1996-05-28 Focus Surgery Inc. Annular array transducer
US5522869A (en) * 1994-05-17 1996-06-04 Burdette; Everette C. Ultrasound device for use in a thermotherapy apparatus
US5524624A (en) * 1994-05-05 1996-06-11 Amei Technologies Inc. Apparatus and method for stimulating tissue growth with ultrasound
US5524620A (en) * 1991-11-12 1996-06-11 November Technologies Ltd. Ablation of blood thrombi by means of acoustic energy
US5526812A (en) * 1993-06-21 1996-06-18 General Electric Company Display system for enhancing visualization of body structures during medical procedures
US6315741B1 (en) * 1997-10-31 2001-11-13 Roy W. Martin Method and apparatus for medical procedures using high-intensity focused ultrasound
US6413254B1 (en) * 2000-01-19 2002-07-02 Medtronic Xomed, Inc. Method of tongue reduction by thermal ablation using high intensity focused ultrasound
US20030176790A1 (en) * 2000-12-28 2003-09-18 Guided Therapy Systems, Inc. Visual imaging system for ultrasonic probe
US6623430B1 (en) * 1997-10-14 2003-09-23 Guided Therapy Systems, Inc. Method and apparatus for safety delivering medicants to a region of tissue using imaging, therapy and temperature monitoring ultrasonic system
US20040267252A1 (en) * 2003-06-30 2004-12-30 Ethicon, Inc. Multi-modality ablation device
US20050154332A1 (en) * 2004-01-12 2005-07-14 Onda Methods and systems for removing hair using focused acoustic energy

Family Cites Families (670)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2427348A (en) 1941-08-19 1947-09-16 Bell Telephone Labor Inc Piezoelectric vibrator
DE2746712C3 (en) 1976-10-19 1980-01-31 List, Hans, Prof. Dipl.-Ing. Dr.Dr. H.C., Graz (Oesterreich)
US4211948A (en) 1978-11-08 1980-07-08 General Electric Company Front surface matched piezoelectric ultrasonic transducer array with wide field of view
US4211949A (en) 1978-11-08 1980-07-08 General Electric Company Wear plate for piezoelectric ultrasonic transducer arrays
JPS6221000B2 (en) 1979-12-14 1987-05-11 Teijin Kk
US4372296A (en) 1980-11-26 1983-02-08 Fahim Mostafa S Treatment of acne and skin disorders and compositions therefor
JPS6336171Y2 (en) 1981-03-12 1988-09-26
DE3300121A1 (en) 1982-01-07 1983-07-14 Technicare Corp Method and apparatus for imaging and thermal treatment of tissue by means of ultrasonically
US4431008A (en) 1982-06-24 1984-02-14 Wanner James F Ultrasonic measurement system using a perturbing field, multiple sense beams and receivers
US4534221A (en) 1982-09-27 1985-08-13 Technicare Corporation Ultrasonic diagnostic imaging systems for varying depths of field
US4507582A (en) 1982-09-29 1985-03-26 New York Institute Of Technology Matching region for damped piezoelectric ultrasonic apparatus
JPH064074B2 (en) 1983-02-14 1994-01-19 株式会社日立製作所 Ultrasonic diagnostic apparatus and the sound speed measuring method using the same
EP0142215A3 (en) 1983-05-26 1987-03-11 Advanced Technology Laboratories, Inc. Ultrasound transducer with improved vibrational modes
US4900540A (en) 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
US4637256A (en) 1983-06-23 1987-01-20 Matsushita Electric Industrial Co., Ltd. Ultrasonic probe having dual-motion transducer
FR2551611B1 (en) 1983-08-31 1986-10-24 Labo Electronique Physique New ultrasound transducer and structure examination apparatus media by ultrasonic echography comprising such structure
US4513750A (en) 1984-02-22 1985-04-30 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method for thermal monitoring subcutaneous tissue
US4620546A (en) 1984-06-30 1986-11-04 Kabushiki Kaisha Toshiba Ultrasound hyperthermia apparatus
DE3501808C2 (en) 1985-01-21 1989-04-27 Siemens Ag, 1000 Berlin Und 8000 Muenchen, De
DE3611669C2 (en) 1985-04-10 1991-09-26 Hitachi, Ltd.
EP0379229B1 (en) 1985-05-20 1994-07-27 Matsushita Electric Industrial Co., Ltd. Ultrasonic probe
US5054310A (en) 1985-09-13 1991-10-08 The California Province Of The Society Of Jesus Test object and method of measurement of an ultrasonic beam
DE3688702D1 (en) 1985-12-13 1993-08-19 Matsushita Electric Ind Co Ltd Ultraschalldiagnosegeraet, based on the CHANGES an acoustic characteristic.
JPH0410280B2 (en) 1986-04-25 1992-02-24
US4803625A (en) 1986-06-30 1989-02-07 Buddy Systems, Inc. Personal health monitor
US4801459A (en) 1986-08-05 1989-01-31 Liburdy Robert P Technique for drug and chemical delivery
JPH0570769B2 (en) 1986-11-13 1993-10-05 Kogyo Gijutsuin
JPS63220847A (en) 1987-03-10 1988-09-14 Matsushita Electric Ind Co Ltd Ultrasonic probe
US5178135A (en) 1987-04-16 1993-01-12 Olympus Optical Co., Ltd. Therapeutical apparatus of extracorporeal type
US4891043A (en) 1987-05-28 1990-01-02 Board Of Trustees Of The University Of Illinois System for selective release of liposome encapsulated material via laser radiation
JPH0348299Y2 (en) 1987-05-29 1991-10-15
US4932414A (en) 1987-11-02 1990-06-12 Cornell Research Foundation, Inc. System of therapeutic ultrasound and real-time ultrasonic scanning
US5040537A (en) 1987-11-24 1991-08-20 Hitachi, Ltd. Method and apparatus for the measurement and medical treatment using an ultrasonic wave
US5251127A (en) 1988-02-01 1993-10-05 Faro Medical Technologies Inc. Computer-aided surgery apparatus
DE69015400D1 (en) 1989-03-27 1995-02-09 Toshiba Kawasaki Kk Mechanical ultrasonic scanner.
US5665141A (en) 1988-03-30 1997-09-09 Arjo Hospital Equipment Ab Ultrasonic treatment process
US6432057B1 (en) 1998-03-31 2002-08-13 Lunar Corporation Stabilizing acoustic coupler for limb densitometry
JP2615132B2 (en) 1988-05-19 1997-05-28 富士通株式会社 Ultrasonic probe
US4966953A (en) 1988-06-02 1990-10-30 Takiron Co., Ltd. Liquid segment polyurethane gel and couplers for ultrasonic diagnostic probe comprising the same
US5018508A (en) 1988-06-03 1991-05-28 Fry Francis J System and method using chemicals and ultrasound or ultrasound alone to replace more conventional surgery
US4896673A (en) 1988-07-15 1990-01-30 Medstone International, Inc. Method and apparatus for stone localization using ultrasound imaging
US5159931A (en) 1988-11-25 1992-11-03 Riccardo Pini Apparatus for obtaining a three-dimensional reconstruction of anatomic structures through the acquisition of echographic images
DE3914619A1 (en) 1989-05-03 1990-11-08 Kontron Elektronik Device for transesophageal echocardiography
US6016255A (en) 1990-11-19 2000-01-18 Dallas Semiconductor Corp. Portable data carrier mounting system
US5212671A (en) 1989-06-22 1993-05-18 Terumo Kabushiki Kaisha Ultrasonic probe having backing material layer of uneven thickness
US5240003A (en) 1989-10-16 1993-08-31 Du-Med B.V. Ultrasonic instrument with a micro motor having stator coils on a flexible circuit board
JPH03136642A (en) 1989-10-20 1991-06-11 Olympus Optical Co Ltd Ultrasonic treatment device
EP0424685B1 (en) 1989-10-27 1995-05-10 Storz Instrument Company Method for driving an ultrasonic transducer
US5070879A (en) 1989-11-30 1991-12-10 Acoustic Imaging Technologies Corp. Ultrasound imaging method and apparatus
DE69027284D1 (en) 1989-12-14 1996-07-11 Aloka Co Ltd Three-dimensional ultrasound scanner
US5469854A (en) 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US5305757A (en) 1989-12-22 1994-04-26 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5580575A (en) 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
JP3015481B2 (en) 1990-03-28 2000-03-06 株式会社東芝 Ultrasound probe system
JP2842453B2 (en) 1990-04-02 1999-01-06 ブラッコ インターナショナル ベスローテン フェンノートシャップ Injectable stable microbubbles suspensions in vivo
JPH03297475A (en) 1990-04-16 1991-12-27 Ken Ishihara Controlling method for emission of medicine by means of resonance sound wave
US5205287A (en) 1990-04-26 1993-04-27 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
DE4117638C2 (en) 1990-05-30 1992-11-12 Kabushiki Kaisha Toshiba, Kawasaki, Kanagawa, Jp
US5215680A (en) 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
US5174929A (en) 1990-08-31 1992-12-29 Ciba-Geigy Corporation Preparation of stable polyvinyl alcohol hydrogel contact lens
US5149319A (en) 1990-09-11 1992-09-22 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids
DE4029175C2 (en) 1990-09-13 1993-10-28 Lauerer Friedrich Electrical protection device
EP0674739B1 (en) 1990-09-17 1998-06-10 Roofer International Ab Method of laying roofing felt and means therefor
JPH0560938B2 (en) 1990-10-12 1993-09-03 Katsuya Takasu
US5685820A (en) 1990-11-06 1997-11-11 Partomed Medizintechnik Gmbh Instrument for the penetration of body tissue
GB9025431D0 (en) 1990-11-22 1991-01-09 Advanced Tech Lab Three dimensional ultrasonic imaging
US5957882A (en) 1991-01-11 1999-09-28 Advanced Cardiovascular Systems, Inc. Ultrasound devices for ablating and removing obstructive matter from anatomical passageways and blood vessels
US5997497A (en) 1991-01-11 1999-12-07 Advanced Cardiovascular Systems Ultrasound catheter having integrated drug delivery system and methods of using same
FR2672486A1 (en) 1991-02-11 1992-08-14 Technomed Int Sa Ultrasound apparatus for extracorporeal therapeutic treatment of superficial varicose veins
US5255681A (en) 1991-03-20 1993-10-26 Olympus Optical Co., Ltd. Ultrasonic wave diagnosing apparatus having an ultrasonic wave transmitting and receiving part transmitting and receiving ultrasonic waves
US5429582A (en) 1991-06-14 1995-07-04 Williams; Jeffery A. Tumor treatment
JP3123559B2 (en) 1991-06-29 2001-01-15 東芝ライテック株式会社 Lighting device
US5383917A (en) * 1991-07-05 1995-01-24 Jawahar M. Desai Device and method for multi-phase radio-frequency ablation
US5327895A (en) 1991-07-10 1994-07-12 Kabushiki Kaisha Toshiba Ultrasonic probe and ultrasonic diagnosing system using ultrasonic probe
US5704361A (en) 1991-11-08 1998-01-06 Mayo Foundation For Medical Education And Research Volumetric image ultrasound transducer underfluid catheter system
US5601526A (en) 1991-12-20 1997-02-11 Technomed Medical Systems Ultrasound therapy apparatus delivering ultrasound waves having thermal and cavitation effects
WO1993016641A1 (en) 1992-02-21 1993-09-02 Diasonics, Inc. Ultrasound intracavity system for imaging therapy planning and treatment of focal disease
JP3386488B2 (en) 1992-03-10 2003-03-17 株式会社東芝 Ultrasound therapy device
US5690608A (en) 1992-04-08 1997-11-25 Asec Co., Ltd. Ultrasonic apparatus for health and beauty
US5257970A (en) 1992-04-09 1993-11-02 Health Research, Inc. In situ photodynamic therapy
JPH0773576B2 (en) 1992-05-27 1995-08-09 アロカ株式会社 An ultrasonic probe for three-dimensional data capture
JP3257640B2 (en) 1992-06-09 2002-02-18 オリンパス光学工業株式会社 Stereo endoscope apparatus
WO1994006380A1 (en) 1992-09-16 1994-03-31 Hitachi, Ltd. Ultrasonic irradiation apparatus and processor using the same
US5391197A (en) 1992-11-13 1995-02-21 Dornier Medical Systems, Inc. Ultrasound thermotherapy probe
US5620479A (en) 1992-11-13 1997-04-15 The Regents Of The University Of California Method and apparatus for thermal therapy of tumors
US6537306B1 (en) 1992-11-13 2003-03-25 The Regents Of The University Of California Method of manufacture of a transurethral ultrasound applicator for prostate gland thermal therapy
US5609562A (en) 1993-11-16 1997-03-11 Worldwide Optical Trocar Licensing Corporation Visually directed trocar and method
US5370122A (en) 1992-11-18 1994-12-06 Kunig; Horst E. Method and apparatus for measuring myocardial impairment, dysfunctions, sufficiency, and insufficiency
JP3272792B2 (en) 1992-12-15 2002-04-08 フクダ電子株式会社 Ultrasonic coupler manufacturing method
US5842473A (en) 1993-11-29 1998-12-01 Life Imaging Systems Three-dimensional imaging system
US5423220A (en) 1993-01-29 1995-06-13 Parallel Design Ultrasonic transducer array and manufacturing method thereof
DE4302538C1 (en) 1993-01-29 1994-04-07 Siemens Ag Ultrasonic therapy device for tumour treatment lithotripsy or osteorestoration - with ultrasonic imaging and ultrasonic treatment modes using respective acoustic wave frequencies
DE4302537C1 (en) 1993-01-29 1994-04-28 Siemens Ag Ultrasound imaging and therapy device - generates imaging waves and focussed treatment waves having two differing frequencies for location and treatment of e.g tumours
US5453575A (en) 1993-02-01 1995-09-26 Endosonics Corporation Apparatus and method for detecting blood flow in intravascular ultrasonic imaging
US6719755B2 (en) 1996-10-22 2004-04-13 Epicor Medical, Inc. Methods and devices for ablation
EP0627206B1 (en) 1993-03-12 2002-11-20 Kabushiki Kaisha Toshiba Apparatus for ultrasound medical treatment
US5307812A (en) 1993-03-26 1994-05-03 General Electric Company Heat surgery system monitored by real-time magnetic resonance profiling
US5305756A (en) 1993-04-05 1994-04-26 Advanced Technology Laboratories, Inc. Volumetric ultrasonic imaging with diverging elevational ultrasound beams
WO1994023793A1 (en) 1993-04-15 1994-10-27 Siemens Aktiengesellschaft Therapeutic appliance for the treatment of conditions of the heart and of blood vessels in the vicinity of the heart
DE9422172U1 (en) 1993-04-26 1998-08-06 Univ St Louis Indication of the position of a surgical probe
DE4318237A1 (en) 1993-06-01 1994-12-08 Storz Medical Ag An apparatus for treatment of biological tissue and Körperkonkrementen
US5392259A (en) 1993-06-15 1995-02-21 Bolorforosh; Mir S. S. Micro-grooves for the design of wideband clinical ultrasonic transducers
US5398689A (en) 1993-06-16 1995-03-21 Hewlett-Packard Company Ultrasonic probe assembly and cable therefor
DE69414121T2 (en) 1993-07-26 1999-06-10 Technomed Medical Systems Endoscopic probe for illustration and therapy and their treatment system
JP2998505B2 (en) 1993-07-29 2000-01-11 富士写真光機株式会社 Radial ultrasonic scanning device
US5438998A (en) 1993-09-07 1995-08-08 Acuson Corporation Broadband phased array transducer design with frequency controlled two dimension capability and methods for manufacture thereof
US5792058A (en) 1993-09-07 1998-08-11 Acuson Corporation Broadband phased array transducer with wide bandwidth, high sensitivity and reduced cross-talk and method for manufacture thereof
US5379773A (en) 1993-09-17 1995-01-10 Hornsby; James J. Echographic suction cannula and electronics therefor
US5661235A (en) 1993-10-01 1997-08-26 Hysitron Incorporated Multi-dimensional capacitive transducer
US20050288748A1 (en) 1993-10-04 2005-12-29 Huan-Chen Li Medical device for treating skin problems
US5647373A (en) 1993-11-07 1997-07-15 Ultra-Guide Ltd. Articulated needle guide for ultrasound imaging and method of using same
US5526814A (en) 1993-11-09 1996-06-18 General Electric Company Automatically positioned focussed energy system guided by medical imaging
US20020169394A1 (en) 1993-11-15 2002-11-14 Eppstein Jonathan A. Integrated tissue poration, fluid harvesting and analysis device, and method therefor
JPH07136162A (en) 1993-11-17 1995-05-30 Fujitsu Ltd Ultrasonic coupler
US5471988A (en) 1993-12-24 1995-12-05 Olympus Optical Co., Ltd. Ultrasonic diagnosis and therapy system in which focusing point of therapeutic ultrasonic wave is locked at predetermined position within observation ultrasonic scanning range
JPH07184907A (en) 1993-12-28 1995-07-25 Toshiba Corp Ultrasonic treating device
DE4443947B4 (en) 1994-01-14 2005-09-22 Siemens Ag endoscope
US5511296A (en) 1994-04-08 1996-04-30 Hewlett Packard Company Method for making integrated matching layer for ultrasonic transducers
WO1995029737A1 (en) 1994-05-03 1995-11-09 Board Of Regents, The University Of Texas System Apparatus and method for noninvasive doppler ultrasound-guided real-time control of tissue damage in thermal therapy
US5396143A (en) 1994-05-20 1995-03-07 Hewlett-Packard Company Elevation aperture control of an ultrasonic transducer
US5575807A (en) 1994-06-10 1996-11-19 Zmd Corporation Medical device power supply with AC disconnect alarm and method of supplying power to a medical device
US5560362A (en) 1994-06-13 1996-10-01 Acuson Corporation Active thermal control of ultrasound transducers
US6325798B1 (en) 1998-02-19 2001-12-04 Curon Medical, Inc. Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions
US5540235A (en) 1994-06-30 1996-07-30 Wilson; John R. Adaptor for neurophysiological monitoring with a personal computer
FR2722358B1 (en) 1994-07-08 1996-08-14 Thomson Csf acoustic transducer multifrequency wide strips
DE19527245A1 (en) 1994-08-30 1996-05-23 Vingmed Sound As Device for endoscopic or gastroscopic investigations
US5829444A (en) 1994-09-15 1998-11-03 Visualization Technology, Inc. Position tracking and imaging system for use in medical applications
US5694936A (en) 1994-09-17 1997-12-09 Kabushiki Kaisha Toshiba Ultrasonic apparatus for thermotherapy with variable frequency for suppressing cavitation
US5810009A (en) 1994-09-27 1998-09-22 Kabushiki Kaisha Toshiba Ultrasonic probe, ultrasonic probe device having the ultrasonic probe, and method of manufacturing the ultrasonic probe
US5503152A (en) 1994-09-28 1996-04-02 Tetrad Corporation Ultrasonic transducer assembly and method for three-dimensional imaging
US5577507A (en) 1994-11-21 1996-11-26 General Electric Company Compound lens for ultrasound transducer probe
US5573497A (en) 1994-11-30 1996-11-12 Technomed Medical Systems And Institut National High-intensity ultrasound therapy method and apparatus with controlled cavitation effect and reduced side lobes
DE4446429C1 (en) 1994-12-23 1996-08-22 Siemens Ag An apparatus for treating an object with focused ultrasound waves
US5999843A (en) 1995-01-03 1999-12-07 Omnicorder Technologies, Inc. Detection of cancerous lesions by their effect on the spatial homogeneity of skin temperature
US5626554A (en) 1995-02-21 1997-05-06 Exogen, Inc. Gel containment structure
US6019724A (en) 1995-02-22 2000-02-01 Gronningsaeter; Aage Method for ultrasound guidance during clinical procedures
DE19609034C2 (en) 1995-03-10 1998-03-05 Karlsruhe Forschzent Device for guiding surgical instruments for endoscopic surgery
US6246898B1 (en) 1995-03-28 2001-06-12 Sonometrics Corporation Method for carrying out a medical procedure using a three-dimensional tracking and imaging system
US5658328A (en) 1995-03-30 1997-08-19 Johnson; Gerald W. Endoscopic assisted mastopexy
US5873902A (en) 1995-03-31 1999-02-23 Focus Surgery, Inc. Ultrasound intensity determining method and apparatus
US5899861A (en) 1995-03-31 1999-05-04 Siemens Medical Systems, Inc. 3-dimensional volume by aggregating ultrasound fields of view
US6093883A (en) 1997-07-15 2000-07-25 Focus Surgery, Inc. Ultrasound intensity determining method and apparatus
EP0734742B1 (en) 1995-03-31 2005-05-11 Kabushiki Kaisha Toshiba Ultrasound therapeutic apparatus
US5577502A (en) 1995-04-03 1996-11-26 General Electric Company Imaging of interventional devices during medical procedures
US5924989A (en) 1995-04-03 1999-07-20 Polz; Hans Method and device for capturing diagnostically acceptable three-dimensional ultrasound image data records
US5644085A (en) 1995-04-03 1997-07-01 General Electric Company High density integrated ultrasonic phased array transducer and a method for making
US5701900A (en) 1995-05-01 1997-12-30 Cedars-Sinai Medical Center Ultrasonic transducer orientation sensing and display apparatus and method
US5735280A (en) 1995-05-02 1998-04-07 Heart Rhythm Technologies, Inc. Ultrasound energy delivery system and method
US20030212393A1 (en) 1996-01-05 2003-11-13 Knowlton Edward W. Handpiece with RF electrode and non-volatile memory
US6470216B1 (en) 1995-05-05 2002-10-22 Thermage, Inc. Method for smoothing contour irregularities of skin surface
US7006874B2 (en) 1996-01-05 2006-02-28 Thermage, Inc. Treatment apparatus with electromagnetic energy delivery device and non-volatile memory
US5755753A (en) 1995-05-05 1998-05-26 Thermage, Inc. Method for controlled contraction of collagen tissue
US7473251B2 (en) 1996-01-05 2009-01-06 Thermage, Inc. Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient
US6241753B1 (en) 1995-05-05 2001-06-05 Thermage, Inc. Method for scar collagen formation and contraction
US6350276B1 (en) 1996-01-05 2002-02-26 Thermage, Inc. Tissue remodeling apparatus containing cooling fluid
US7115123B2 (en) 1996-01-05 2006-10-03 Thermage, Inc. Handpiece with electrode and non-volatile memory
US6425912B1 (en) * 1995-05-05 2002-07-30 Thermage, Inc. Method and apparatus for modifying skin surface and soft tissue structure
US5660836A (en) 1995-05-05 1997-08-26 Knowlton; Edward W. Method and apparatus for controlled contraction of collagen tissue
US20040000316A1 (en) 1996-01-05 2004-01-01 Knowlton Edward W. Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient
US7189230B2 (en) 1996-01-05 2007-03-13 Thermage, Inc. Method for treating skin and underlying tissue
US5558092A (en) 1995-06-06 1996-09-24 Imarx Pharmaceutical Corp. Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
US5755228A (en) 1995-06-07 1998-05-26 Hologic, Inc. Equipment and method for calibration and quality assurance of an ultrasonic bone anaylsis apparatus
US6059727A (en) 1995-06-15 2000-05-09 The Regents Of The University Of Michigan Method and apparatus for composition and display of three-dimensional image from two-dimensional ultrasound scan data
US5655538A (en) 1995-06-19 1997-08-12 General Electric Company Ultrasonic phased array transducer with an ultralow impedance backfill and a method for making
US6248073B1 (en) 1995-06-29 2001-06-19 Teratech Corporation Ultrasound scan conversion with spatial dithering
WO1997003609A1 (en) 1995-07-16 1997-02-06 Ultra-Guide Ltd. Free-hand aiming of a needle guide
US5706564A (en) 1995-07-27 1998-01-13 General Electric Company Method for designing ultrasonic transducers using constraints on feasibility and transitional Butterworth-Thompson spectrum
US5814599A (en) 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs
DE19528754A1 (en) 1995-08-04 1997-02-06 Trw Repa Gmbh Airbag restraint module
JPH0947458A (en) 1995-08-09 1997-02-18 Toshiba Corp Ultrasonic therapeupic device and applicator
US5638819A (en) 1995-08-29 1997-06-17 Manwaring; Kim H. Method and apparatus for guiding an instrument to a target
US5662116A (en) 1995-09-12 1997-09-02 Fuji Photo Optical Co., Ltd. Multi-plane electronic scan ultrasound probe
US5622175A (en) 1995-09-29 1997-04-22 Hewlett-Packard Company Miniaturization of a rotatable sensor
US5615091A (en) 1995-10-11 1997-03-25 Biochem International, Inc. Isolation transformer for medical equipment
US5618275A (en) 1995-10-27 1997-04-08 Sonex International Corporation Ultrasonic method and apparatus for cosmetic and dermatological applications
US6135971A (en) 1995-11-09 2000-10-24 Brigham And Women's Hospital Apparatus for deposition of ultrasound energy in body tissue
US5895356A (en) 1995-11-15 1999-04-20 American Medical Systems, Inc. Apparatus and method for transurethral focussed ultrasound therapy
CN1617689A (en) 1999-06-30 2005-05-18 塞梅格公司 Fluid delivery apparatus
US5715823A (en) 1996-02-27 1998-02-10 Atlantis Diagnostics International, L.L.C. Ultrasonic diagnostic imaging system with universal access to diagnostic information and images
US5603323A (en) 1996-02-27 1997-02-18 Advanced Technology Laboratories, Inc. Medical ultrasonic diagnostic system with upgradeable transducer probes and other features
US6190323B1 (en) 1996-03-13 2001-02-20 Agielnt Technologies Direct contact scanner and related method
US5817013A (en) 1996-03-19 1998-10-06 Enable Medical Corporation Method and apparatus for the minimally invasive harvesting of a saphenous vein and the like
US5676692A (en) 1996-03-28 1997-10-14 Indianapolis Center For Advanced Research, Inc. Focussed ultrasound tissue treatment method
US5655535A (en) 1996-03-29 1997-08-12 Siemens Medical Systems, Inc. 3-Dimensional compound ultrasound field of view
US5673699A (en) 1996-05-31 1997-10-07 Duke University Method and apparatus for abberation correction in the presence of a distributed aberrator
US5749364A (en) 1996-06-21 1998-05-12 Acuson Corporation Method and apparatus for mapping pressure and tissue properties
US5746762A (en) 1996-06-24 1998-05-05 Bass; Lawrence S. Device and method for surgical flap dissection
US6234990B1 (en) 1996-06-28 2001-05-22 Sontra Medical, Inc. Ultrasound enhancement of transdermal transport
US5671746A (en) 1996-07-29 1997-09-30 Acuson Corporation Elevation steerable ultrasound transducer array
US5763886A (en) 1996-08-07 1998-06-09 Northrop Grumman Corporation Two-dimensional imaging backscatter probe
US5984882A (en) 1996-08-19 1999-11-16 Angiosonics Inc. Methods for prevention and treatment of cancer and other proliferative diseases with ultrasonic energy
US5971949A (en) 1996-08-19 1999-10-26 Angiosonics Inc. Ultrasound transmission apparatus and method of using same
US6605041B2 (en) 1996-08-22 2003-08-12 Synthes (U.S.A.) 3-D ultrasound recording device
EP0929347B1 (en) 1996-08-22 2004-10-27 Storz Medical Ag Device for treating the heart
US5844140A (en) 1996-08-27 1998-12-01 Seale; Joseph B. Ultrasound beam alignment servo
DE19635593C1 (en) 1996-09-02 1998-04-23 Siemens Ag Ultrasonic transducers for diagnostic and therapeutic use
US5795297A (en) 1996-09-12 1998-08-18 Atlantis Diagnostics International, L.L.C. Ultrasonic diagnostic imaging system with personal computer architecture
US5727554A (en) 1996-09-19 1998-03-17 University Of Pittsburgh Of The Commonwealth System Of Higher Education Apparatus responsive to movement of a patient during treatment/diagnosis
US5879303A (en) 1996-09-27 1999-03-09 Atl Ultrasound Ultrasonic diagnostic imaging of response frequency differing from transmit frequency
US5957941A (en) 1996-09-27 1999-09-28 Boston Scientific Corporation Catheter system and drive assembly thereof
US5665053A (en) 1996-09-27 1997-09-09 Jacobs; Robert A. Apparatus for performing endermology with ultrasound
US6283919B1 (en) 1996-11-26 2001-09-04 Atl Ultrasound Ultrasonic diagnostic imaging with blended tissue harmonic signals
US5746005A (en) 1996-10-22 1998-05-05 Powerhorse Corporation Angular position sensor
US5769790A (en) 1996-10-25 1998-06-23 General Electric Company Focused ultrasound surgery system guided by ultrasound imaging
DE69732511D1 (en) 1996-10-29 2005-03-24 Koninkl Philips Electronics Nv A method for processing signals from objects with moving parts and echographic apparatus therefor
US5827204A (en) 1996-11-26 1998-10-27 Grandia; Willem Medical noninvasive operations using focused modulated high power ultrasound
US5810008A (en) 1996-12-03 1998-09-22 Isg Technologies Inc. Apparatus and method for visualizing ultrasonic images
FR2756741B1 (en) 1996-12-05 1999-01-08 Cird Galderma Use of a chromophore in a composition intended to be applied on the skin before a laser treatment
US5820564A (en) 1996-12-16 1998-10-13 Albatross Technologies, Inc. Method and apparatus for surface ultrasound imaging
US20040015079A1 (en) 1999-06-22 2004-01-22 Teratech Corporation Ultrasound probe with integrated electronics
WO1998032379A1 (en) 1997-01-27 1998-07-30 Technion Research And Development Foundation Ltd. An ultrasound system and methods utilizing same
US7108663B2 (en) 1997-02-06 2006-09-19 Exogen, Inc. Method and apparatus for cartilage growth stimulation
US7789841B2 (en) 1997-02-06 2010-09-07 Exogen, Inc. Method and apparatus for connective tissue treatment
US5904659A (en) 1997-02-14 1999-05-18 Exogen, Inc. Ultrasonic treatment for wounds
US5853367A (en) 1997-03-17 1998-12-29 General Electric Company Task-interface and communications system and method for ultrasound imager control
US5938612A (en) 1997-05-05 1999-08-17 Creare Inc. Multilayer ultrasonic transducer array including very thin layer of transducer elements
US5840032A (en) 1997-05-07 1998-11-24 General Electric Company Method and apparatus for three-dimensional ultrasound imaging using transducer array having uniform elevation beamwidth
DE19880830B4 (en) 1997-05-15 2006-09-28 Matsushita Electric Works Ltd., Kadoma-Shi Ultrasonic device
US6128522A (en) 1997-05-23 2000-10-03 Transurgical, Inc. MRI-guided therapeutic unit and methods
US5931805A (en) 1997-06-02 1999-08-03 Pharmasonics, Inc. Catheters comprising bending transducers and methods for their use
JP3783339B2 (en) 1997-06-13 2006-06-07 松下電工株式会社 Ultrasonic beauty instrument
US5968034A (en) 1997-06-24 1999-10-19 Laser Aesthetics, Inc. Pulsed filament lamp for dermatological treatment
US5810888A (en) 1997-06-26 1998-09-22 Massachusetts Institute Of Technology Thermodynamic adaptive phased array system for activating thermosensitive liposomes in targeted drug delivery
US5876341A (en) 1997-06-30 1999-03-02 Siemens Medical Systems, Inc. Removing beam interleave effect on doppler spectrum in ultrasound imaging
US6126619A (en) 1997-09-02 2000-10-03 Transon Llc Multiple transducer assembly and method for coupling ultrasound energy to a body
US20030040442A1 (en) 1997-07-02 2003-02-27 Nsk Ltd. Rolling bearing
US6547788B1 (en) 1997-07-08 2003-04-15 Atrionx, Inc. Medical device with sensor cooperating with expandable member
US6176840B1 (en) 1997-08-11 2001-01-23 Matsushita Electric Works, Ltd. Ultrasonic cosmetic treatment device
US20020169442A1 (en) 1997-08-12 2002-11-14 Joseph Neev Device and a method for treating skin conditions
JP2001514921A (en) 1997-08-13 2001-09-18 サークス, インコーポレイテッド Non-invasive devices, methods for tissue shrinkage and systems,
US6413253B1 (en) 1997-08-16 2002-07-02 Cooltouch Corporation Subsurface heating of material
US5990598A (en) 1997-09-23 1999-11-23 Hewlett-Packard Company Segment connections for multiple elevation transducers
US6113558A (en) 1997-09-29 2000-09-05 Angiosonics Inc. Pulsed mode lysis method
US5923099A (en) 1997-09-30 1999-07-13 Lam Research Corporation Intelligent backup power controller
US6049159A (en) 1997-10-06 2000-04-11 Albatros Technologies, Inc. Wideband acoustic transducer
US6500121B1 (en) 1997-10-14 2002-12-31 Guided Therapy Systems, Inc. Imaging, therapy, and temperature monitoring ultrasonic system
US6050943A (en) 1997-10-14 2000-04-18 Guided Therapy Systems, Inc. Imaging, therapy, and temperature monitoring ultrasonic system
US6325758B1 (en) 1997-10-27 2001-12-04 Nomos Corporation Method and apparatus for target position verification
US6071239A (en) 1997-10-27 2000-06-06 Cribbs; Robert W. Method and apparatus for lipolytic therapy using ultrasound energy
US20020040199A1 (en) 1997-12-29 2002-04-04 Klopotek Peter J. Method and apparatus for therapeutic treatment of skin
US20080027328A1 (en) 1997-12-29 2008-01-31 Julia Therapeutics, Llc Multi-focal treatment of skin with acoustic energy
US20080146970A1 (en) 2005-12-06 2008-06-19 Julia Therapeutics, Llc Gel dispensers for treatment of skin with acoustic energy
US20060184071A1 (en) 1997-12-29 2006-08-17 Julia Therapeutics, Llc Treatment of skin with acoustic energy
US6113559A (en) 1997-12-29 2000-09-05 Klopotek; Peter J. Method and apparatus for therapeutic treatment of skin with ultrasound
US6171244B1 (en) 1997-12-31 2001-01-09 Acuson Corporation Ultrasonic system and method for storing data
US6575956B1 (en) 1997-12-31 2003-06-10 Pharmasonics, Inc. Methods and apparatus for uniform transcutaneous therapeutic ultrasound
US20030229331A1 (en) 1999-11-05 2003-12-11 Pharmasonics, Inc. Methods and apparatus for uniform transcutaneous therapeutic ultrasound
JPH11244386A (en) 1998-01-01 1999-09-14 Ge Yokogawa Medical Systems Ltd Method for stopping blood circulation and heater
DE19800416C2 (en) 1998-01-08 2002-09-19 Storz Karl Gmbh & Co Kg A device for treatment of body tissue, in particular near the surface soft tissue by means of ultrasound
CN1058905C (en) 1998-01-25 2000-11-29 重庆海扶(Hifu)技术有限公司 High-intensity focus supersonic tumour scanning therapy system
US6370411B1 (en) 1998-02-10 2002-04-09 Biosense, Inc. Catheter calibration
US20020055702A1 (en) 1998-02-10 2002-05-09 Anthony Atala Ultrasound-mediated drug delivery
US6101407A (en) 1998-02-13 2000-08-08 Eastman Kodak Company Method and system for remotely viewing and configuring output from a medical imaging device
US6039689A (en) 1998-03-11 2000-03-21 Riverside Research Institute Stripe electrode transducer for use with therapeutic ultrasonic radiation treatment
US6013032A (en) 1998-03-13 2000-01-11 Hewlett-Packard Company Beamforming methods and apparatus for three-dimensional ultrasound imaging using two-dimensional transducer array
US6685640B1 (en) 1998-03-30 2004-02-03 Focus Surgery, Inc. Ablation system
WO1999049788A9 (en) 1998-03-30 2000-02-17 Focus Surgery Inc Ablation system
US6039048A (en) 1998-04-08 2000-03-21 Silberg; Barry External ultrasound treatment of connective tissue
US20040073115A1 (en) 2000-08-24 2004-04-15 Timi 3 Systems, Inc. Systems and methods for applying ultrasound energy to increase tissue perfusion and/or vasodilation without substantial deep heating of tissue
US6004262A (en) 1998-05-04 1999-12-21 Ad-Tech Medical Instrument Corp. Visually-positioned electrical monitoring apparatus
US6022327A (en) 1998-05-04 2000-02-08 Chang; Henry Ping Facial steamer machine with detachable function units
US5977538A (en) 1998-05-11 1999-11-02 Imarx Pharmaceutical Corp. Optoacoustic imaging system
US6186951B1 (en) 1998-05-26 2001-02-13 Riverside Research Institute Ultrasonic systems and methods for fluid perfusion and flow rate measurement
US6432101B1 (en) 1998-05-28 2002-08-13 Pearl Technology Holdings, Llc Surgical device for performing face-lifting using electromagnetic radiation
US6699237B2 (en) 1999-12-30 2004-03-02 Pearl Technology Holdings, Llc Tissue-lifting device
US7494488B2 (en) 1998-05-28 2009-02-24 Pearl Technology Holdings, Llc Facial tissue strengthening and tightening device and methods
US6440121B1 (en) 1998-05-28 2002-08-27 Pearl Technology Holdings, Llc. Surgical device for performing face-lifting surgery using radiofrequency energy
US6077294A (en) 1998-06-11 2000-06-20 Cynosure, Inc. Method for non-invasive wrinkle removal and skin treatment
US6425865B1 (en) 1998-06-12 2002-07-30 The University Of British Columbia Robotically assisted medical ultrasound
US6322532B1 (en) 1998-06-24 2001-11-27 3M Innovative Properties Company Sonophoresis method and apparatus
US20030216795A1 (en) 1999-07-07 2003-11-20 Yoram Harth Apparatus and method for high energy photodynamic therapy of acne vulgaris, seborrhea and other skin disorders
US6036646A (en) 1998-07-10 2000-03-14 Guided Therapy Systems, Inc. Method and apparatus for three dimensional ultrasound imaging
US6889089B2 (en) 1998-07-28 2005-05-03 Scimed Life Systems, Inc. Apparatus and method for treating tumors near the surface of an organ
WO2000006032A1 (en) 1998-07-29 2000-02-10 Pharmasonics, Inc. Ultrasonic enhancement of drug injection
US20030009153A1 (en) 1998-07-29 2003-01-09 Pharmasonics, Inc. Ultrasonic enhancement of drug injection
US6443914B1 (en) 1998-08-10 2002-09-03 Lysonix, Inc. Apparatus and method for preventing and treating cellulite
US6042556A (en) 1998-09-04 2000-03-28 University Of Washington Method for determining phase advancement of transducer elements in high intensity focused ultrasound
EP1112029A4 (en) 1998-09-11 2007-06-06 Gr Intellectual Reserve Llc Methods for using resonant acoustic and/or resonant acousto-em energy to detect and/or effect structures
EP1113844A1 (en) 1998-09-16 2001-07-11 Ultra Cure Ltd. Method for peeling of epithelial tissue and apparatus and system for use therefor
US6425867B1 (en) 1998-09-18 2002-07-30 University Of Washington Noise-free real time ultrasonic imaging of a treatment site undergoing high intensity focused ultrasound therapy
US7686763B2 (en) 1998-09-18 2010-03-30 University Of Washington Use of contrast agents to increase the effectiveness of high intensity focused ultrasound therapy
US7510536B2 (en) 1999-09-17 2009-03-31 University Of Washington Ultrasound guided high intensity focused ultrasound treatment of nerves
JP4460691B2 (en) 1998-09-30 2010-05-12 株式会社東芝 Ultrasound therapy device
JP3330092B2 (en) 1998-09-30 2002-09-30 松下電器産業株式会社 The ultrasonic diagnostic apparatus
JP2002527162A (en) 1998-10-09 2002-08-27 ウルトラ キュアー リミテッド Method and apparatus for hair removal
US6540700B1 (en) 1998-10-26 2003-04-01 Kabushiki Kaisha Toshiba Ultrasound treatment apparatus
JP4095729B2 (en) 1998-10-26 2008-06-04 株式会社日立メディコ Therapeutic ultrasound device
US6948843B2 (en) 1998-10-28 2005-09-27 Covaris, Inc. Method and apparatus for acoustically controlling liquid solutions in microfluidic devices
DE69937747D1 (en) 1998-10-28 2008-01-24 Covaris Inc Apparatus and method for controlling an acoustic treatment
US6080108A (en) 1998-11-17 2000-06-27 Atl Ultrasound, Inc. Scanning aid for quantified three dimensional ultrasonic diagnostic imaging
US6159150A (en) 1998-11-20 2000-12-12 Acuson Corporation Medical diagnostic ultrasonic imaging system with auxiliary processor
WO2000030554A1 (en) 1998-11-20 2000-06-02 Jones Joie P Methods for selectively dissolving and removing materials using ultra-high frequency ultrasound
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US6936044B2 (en) 1998-11-30 2005-08-30 Light Bioscience, Llc Method and apparatus for the stimulation of hair growth
US6676655B2 (en) 1998-11-30 2004-01-13 Light Bioscience L.L.C. Low intensity light therapy for the manipulation of fibroblast, and fibroblast-derived mammalian cells and collagen
JP4089058B2 (en) 1998-12-10 2008-05-21 ソニー株式会社 Cleaning device and cleaning method of the printing screen
US6309355B1 (en) 1998-12-22 2001-10-30 The Regents Of The University Of Michigan Method and assembly for performing ultrasound surgery using cavitation
US6325769B1 (en) * 1998-12-29 2001-12-04 Collapeutics, Llc Method and apparatus for therapeutic treatment of skin
US6296619B1 (en) 1998-12-30 2001-10-02 Pharmasonics, Inc. Therapeutic ultrasonic catheter for delivering a uniform energy dose
US6428532B1 (en) 1998-12-30 2002-08-06 The General Hospital Corporation Selective tissue targeting by difference frequency of two wavelengths
US6183773B1 (en) 1999-01-04 2001-02-06 The General Hospital Corporation Targeting of sebaceous follicles as a treatment of sebaceous gland disorders
JP2000214966A (en) 1999-01-20 2000-08-04 Ricoh Co Ltd Portable information processor
US6200308B1 (en) 1999-01-29 2001-03-13 Candela Corporation Dynamic cooling of tissue for radiation treatment
US6139499A (en) 1999-02-22 2000-10-31 Wilk; Peter J. Ultrasonic medical system and associated method
KR20000059516A (en) 1999-03-04 2000-10-05 임영환 Method of transmitting and executing multimedia presentation mail and apparatus thereby
ES2240078T3 (en) 1999-03-09 2005-10-16 Thermage, Inc. Apparatus for treating tissue.
US6508774B1 (en) 1999-03-09 2003-01-21 Transurgical, Inc. Hifu applications with feedback control
US6775404B1 (en) 1999-03-18 2004-08-10 University Of Washington Apparatus and method for interactive 3D registration of ultrasound and magnetic resonance images based on a magnetic position sensor
US6375672B1 (en) 1999-03-22 2002-04-23 Board Of Trustees Of Michigan State University Method for controlling the chemical and heat induced responses of collagenous materials
US6488626B1 (en) 1999-04-07 2002-12-03 Riverside Research Institute Ultrasonic sensing by induced tissue motion
US6408212B1 (en) 1999-04-13 2002-06-18 Joseph Neev Method for treating acne
US6210327B1 (en) 1999-04-28 2001-04-03 General Electric Company Method and apparatus for sending ultrasound image data to remotely located device
US6268405B1 (en) 1999-05-04 2001-07-31 Porex Surgical, Inc. Hydrogels and methods of making and using same
US6251088B1 (en) 1999-05-12 2001-06-26 Jonathan J. Kaufman Ultrasonic plantar fasciitis therapy: apparatus and method
US6217530B1 (en) 1999-05-14 2001-04-17 University Of Washington Ultrasonic applicator for medical applications
US20030060736A1 (en) 1999-05-14 2003-03-27 Martin Roy W. Lens-focused ultrasonic applicator for medical applications
US6666835B2 (en) 1999-05-14 2003-12-23 University Of Washington Self-cooled ultrasonic applicator for medical applications
US6233476B1 (en) 1999-05-18 2001-05-15 Mediguide Ltd. Medical positioning system
US7399279B2 (en) 1999-05-28 2008-07-15 Physiosonics, Inc Transmitter patterns for multi beam reception
US6193658B1 (en) 1999-06-24 2001-02-27 Martin E Wendelken Method and kit for wound evaluation
US6287257B1 (en) 1999-06-29 2001-09-11 Acuson Corporation Method and system for configuring a medical diagnostic ultrasound imaging system
US6302848B1 (en) 1999-07-01 2001-10-16 Sonotech, Inc. In vivo biocompatible acoustic coupling media
GB9915707D0 (en) 1999-07-05 1999-09-08 Young Michael J R Method and apparatus for focused treatment of subcutaneous blood vessels
CA2377190A1 (en) 1999-07-23 2001-02-01 University Of Florida Ultrasonic guidance of target structures for medical procedures
US6307302B1 (en) 1999-07-23 2001-10-23 Measurement Specialities, Inc. Ultrasonic transducer having impedance matching layer
US6451007B1 (en) 1999-07-29 2002-09-17 Dale E. Koop Thermal quenching of tissue
US6533726B1 (en) 1999-08-09 2003-03-18 Riverside Research Institute System and method for ultrasonic harmonic imaging for therapy guidance and monitoring
US20020173721A1 (en) 1999-08-20 2002-11-21 Novasonics, Inc. User interface for handheld imaging devices
JP3848572B2 (en) 1999-09-10 2006-11-22 プロリズム,インコーポレイテッド Device for closing the anatomy
US8206299B2 (en) 2003-12-16 2012-06-26 University Of Washington Image guided high intensity focused ultrasound treatment of nerves
US6123081A (en) 1999-09-22 2000-09-26 Durette; Jean-Francois Ocular surgical protective shield
US6301989B1 (en) 1999-09-30 2001-10-16 Civco Medical Instruments, Inc. Medical imaging instrument positioning device
US20040158150A1 (en) 1999-10-05 2004-08-12 Omnisonics Medical Technologies, Inc. Apparatus and method for an ultrasonic medical device for tissue remodeling
US6287304B1 (en) 1999-10-15 2001-09-11 Neothermia Corporation Interstitial cauterization of tissue volumes with electrosurgically deployed electrodes
WO2001028623A3 (en) 1999-10-18 2001-09-13 Focus Surgery Inc Split beam transducer
US6440071B1 (en) 1999-10-18 2002-08-27 Guided Therapy Systems, Inc. Peripheral ultrasound imaging system
US20050240170A1 (en) 1999-10-25 2005-10-27 Therus Corporation Insertable ultrasound probes, systems, and methods for thermal therapy
EP1229839A4 (en) 1999-10-25 2005-12-07 Therus Corp Use of focused ultrasound for vascular sealing
US6338716B1 (en) 1999-11-24 2002-01-15 Acuson Corporation Medical diagnostic ultrasonic transducer probe and imaging system for use with a position and orientation sensor
US6626855B1 (en) 1999-11-26 2003-09-30 Therus Corpoation Controlled high efficiency lesion formation using high intensity ultrasound
US6325540B1 (en) 1999-11-29 2001-12-04 General Electric Company Method and apparatus for remotely configuring and servicing a field replaceable unit in a medical diagnostic system
US6356780B1 (en) 1999-12-22 2002-03-12 General Electric Company Method and apparatus for managing peripheral devices in a medical imaging system
JP2004512856A (en) 1999-12-23 2004-04-30 シーラス、コーポレイションTherus Corporation Imaging and therapeutic ultrasound transducer
US6436061B1 (en) 1999-12-29 2002-08-20 Peter D. Costantino Ultrasound treatment of varicose veins
US6595934B1 (en) 2000-01-19 2003-07-22 Medtronic Xomed, Inc. Methods of skin rejuvenation using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions
US6692450B1 (en) 2000-01-19 2004-02-17 Medtronic Xomed, Inc. Focused ultrasound ablation devices having selectively actuatable ultrasound emitting elements and methods of using the same
US7706882B2 (en) 2000-01-19 2010-04-27 Medtronic, Inc. Methods of using high intensity focused ultrasound to form an ablated tissue area
US6409720B1 (en) 2000-01-19 2002-06-25 Medtronic Xomed, Inc. Methods of tongue reduction using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions
US6451013B1 (en) 2000-01-19 2002-09-17 Medtronic Xomed, Inc. Methods of tonsil reduction using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions
US6361531B1 (en) 2000-01-21 2002-03-26 Medtronic Xomed, Inc. Focused ultrasound ablation devices having malleable handle shafts and methods of using the same
US6517484B1 (en) 2000-02-28 2003-02-11 Wilk Patent Development Corporation Ultrasonic imaging system and associated method
US6511427B1 (en) 2000-03-10 2003-01-28 Acuson Corporation System and method for assessing body-tissue properties using a medical ultrasound transducer probe with a body-tissue parameter measurement mechanism
US6428477B1 (en) 2000-03-10 2002-08-06 Koninklijke Philips Electronics, N.V. Delivery of theraputic ultrasound by two dimensional ultrasound array
US6419648B1 (en) 2000-04-21 2002-07-16 Insightec-Txsonics Ltd. Systems and methods for reducing secondary hot spots in a phased array focused ultrasound system
WO2001082778A3 (en) 2000-04-28 2002-08-08 Focus Surgery Inc Ablation system with visualization
WO2001082777A3 (en) 2000-04-29 2002-05-23 Focus Surgery Inc Non-invasive tissue characterization
US6312385B1 (en) 2000-05-01 2001-11-06 Ge Medical Systems Global Technology Company, Llc Method and apparatus for automatic detection and sizing of cystic objects
WO2001089723A1 (en) 2000-05-22 2001-11-29 Miwa Science Laboratory Inc. Ultrasonic irradiation apparatus
WO2002003873A3 (en) 2000-07-10 2002-05-10 Us Health Radiofrequency probes for tissue treatment and methods of use
WO2002009813A1 (en) 2000-07-31 2002-02-07 El. En. S.P.A. Method and device for epilation by ultrasound
JP3556582B2 (en) 2000-08-02 2004-08-18 松下電器産業株式会社 The ultrasonic diagnostic apparatus
CA2422865C (en) 2000-08-16 2012-10-16 The General Hospital Corporation D/B/A Massachusetts General Hospital Aminolevulinic acid photodynamic therapy for treating sebaceous gland disorders
US6790187B2 (en) 2000-08-24 2004-09-14 Timi 3 Systems, Inc. Systems and methods for applying ultrasonic energy
US7335169B2 (en) 2000-08-24 2008-02-26 Timi 3 Systems, Inc. Systems and methods for delivering ultrasound energy at an output power level that remains essentially constant despite variations in transducer impedance
US20020082529A1 (en) 2000-08-24 2002-06-27 Timi 3 Systems, Inc. Systems and methods for applying pulsed ultrasonic energy
US20020072691A1 (en) 2000-08-24 2002-06-13 Timi 3 Systems, Inc. Systems and methods for applying ultrasonic energy to the thoracic cavity
JP2002078764A (en) 2000-09-06 2002-03-19 Purotec Fuji:Kk Portable cosmetic massage machine
US6524250B1 (en) 2000-09-19 2003-02-25 Pearl Technology Holdings, Llc Fat layer thickness mapping system to guide liposuction surgery
JP2004508867A (en) 2000-09-19 2004-03-25 フォーカス サージェリー,インコーポレイテッド Tissue treatment method and apparatus
US6910139B2 (en) 2000-10-02 2005-06-21 Fujitsu Limited Software processing apparatus with a switching processing unit for displaying animation images in an environment operating base on type of power supply
KR100400870B1 (en) 2000-10-10 2003-10-08 김영애 remote dermal diagnosing and curing device
US6882884B1 (en) 2000-10-13 2005-04-19 Soundskin, L.L.C. Process for the stimulation of production of extracellular dermal proteins in human tissue
JP2001170068A (en) 2000-10-16 2001-06-26 Toshiba Corp Ultrasonic treatment instrument
US7778685B2 (en) 2000-10-18 2010-08-17 Paieon Inc. Method and system for positioning a device in a tubular organ
US6540685B1 (en) 2000-11-09 2003-04-01 Koninklijke Philips Electronics N.V. Ultrasound diagnostic device
US6821274B2 (en) 2001-03-07 2004-11-23 Gendel Ltd. Ultrasound therapy for selective cell ablation
JP2004520870A (en) 2000-11-28 2004-07-15 アレズ フィジオニックス リミテッド Non-invasive physiological assessment system and method
US6618620B1 (en) 2000-11-28 2003-09-09 Txsonics Ltd. Apparatus for controlling thermal dosing in an thermal treatment system
GB0030449D0 (en) 2000-12-13 2001-01-24 Deltex Guernsey Ltd Improvements in or relating to doppler haemodynamic monitors
US6746444B2 (en) 2000-12-18 2004-06-08 Douglas J. Key Method of amplifying a beneficial selective skin response to light energy
US6761729B2 (en) 2000-12-22 2004-07-13 Advanced Medicalapplications, Inc. Wound treatment method and device with combination of ultrasound and laser energy
US6626854B2 (en) 2000-12-27 2003-09-30 Insightec - Txsonics Ltd. Systems and methods for ultrasound assisted lipolysis
US6645162B2 (en) 2000-12-27 2003-11-11 Insightec - Txsonics Ltd. Systems and methods for ultrasound assisted lipolysis
CA2433022C (en) 2000-12-28 2016-12-06 Palomar Medical Technologies, Inc. Method and apparatus for therapeutic emr treatment of the skin
US7914453B2 (en) 2000-12-28 2011-03-29 Ardent Sound, Inc. Visual imaging system for ultrasonic probe
US6607498B2 (en) 2001-01-03 2003-08-19 Uitra Shape, Inc. Method and apparatus for non-invasive body contouring by lysing adipose tissue
WO2002054827A3 (en) 2001-01-05 2003-12-24 Bjoern A J Angelsen Wideband transducer
US6569099B1 (en) 2001-01-12 2003-05-27 Eilaz Babaev Ultrasonic method and device for wound treatment
JP2002209905A (en) 2001-01-22 2002-07-30 Hitachi Medical Corp Ultrasonic therapy probe and ultrasonic therapy apparatus
US6626834B2 (en) 2001-01-25 2003-09-30 Shane Dunne Spiral scanner with electronic control
US6740040B1 (en) 2001-01-30 2004-05-25 Advanced Cardiovascular Systems, Inc. Ultrasound energy driven intraventricular catheter to treat ischemia
JP2002238919A (en) 2001-02-20 2002-08-27 Olympus Optical Co Ltd Control apparatus for medical care system and medical care system
JP2002248153A (en) 2001-02-23 2002-09-03 Matsushita Electric Works Ltd Ultrasonic cosmetic device
US6569108B2 (en) 2001-03-28 2003-05-27 Profile, Llc Real time mechanical imaging of the prostate
US6804327B2 (en) 2001-04-03 2004-10-12 Lambda Physik Ag Method and apparatus for generating high output power gas discharge based source of extreme ultraviolet radiation and/or soft x-rays
US20020165529A1 (en) 2001-04-05 2002-11-07 Danek Christopher James Method and apparatus for non-invasive energy delivery
US6478754B1 (en) 2001-04-23 2002-11-12 Advanced Medical Applications, Inc. Ultrasonic method and device for wound treatment
WO2002087692A9 (en) 2001-04-26 2004-04-08 Procter & Gamble A method and apparatus for the treatment of cosmetic skin conditioins
US6663627B2 (en) 2001-04-26 2003-12-16 Medtronic, Inc. Ablation system and method of use
GB0111440D0 (en) 2001-05-10 2001-07-04 Procter & Gamble Method and kit for the treatment or prevention of cosmetic skin conditions
JP3937755B2 (en) 2001-05-28 2007-06-27 松下電工株式会社 Ultrasonic beauty instrument
US7846096B2 (en) 2001-05-29 2010-12-07 Ethicon Endo-Surgery, Inc. Method for monitoring of medical treatment using pulse-echo ultrasound
US20030013972A1 (en) 2001-05-29 2003-01-16 Makin Inder Raj. S. Treatment of lung lesions using ultrasound
US7058440B2 (en) 2001-06-28 2006-06-06 Koninklijke Philips Electronics N.V. Dynamic computed tomography imaging using positional state modeling
US6659956B2 (en) 2001-06-29 2003-12-09 Barzell-Whitmore Maroon Bells, Inc. Medical instrument positioner
US7056331B2 (en) 2001-06-29 2006-06-06 Quill Medical, Inc. Suture method
US6932771B2 (en) 2001-07-09 2005-08-23 Civco Medical Instruments Co., Inc. Tissue warming device and method
JP5041636B2 (en) 2001-07-12 2012-10-03 株式会社Adeka Medical device antimicrobial composition
FR2827149B1 (en) 2001-07-13 2003-10-10 Technomed Medical Systems sonication probe FOCUSED
JP2003050298A (en) 2001-08-06 2003-02-21 Fuji Photo Film Co Ltd Radiographic image conversion panel and its manufacturing method
US7018396B2 (en) 2001-08-07 2006-03-28 New England Medical Center Hospitals, Inc. Method of treating acne
US20030032900A1 (en) 2001-08-08 2003-02-13 Engii (2001) Ltd. System and method for facial treatment
DE10140064A1 (en) 2001-08-16 2003-03-13 Rainer Weismueller Cosmetic or medical treatment of the skin using ultrasound waves, e.g. permanent hair removal using a simple device comprising a mechanical oscillator and focussing lenses with a spacer for varying the distance to the skin
US7094252B2 (en) 2001-08-21 2006-08-22 Cooltouch Incorporated Enhanced noninvasive collagen remodeling
US6773409B2 (en) 2001-09-19 2004-08-10 Surgrx Llc Surgical system for applying ultrasonic energy to tissue
US6638226B2 (en) 2001-09-28 2003-10-28 Teratech Corporation Ultrasound imaging system
CA2406684A1 (en) 2001-10-05 2003-04-05 Queen's University At Kingston Ultrasound transducer array
US6709397B2 (en) 2001-10-16 2004-03-23 Envisioneering, L.L.C. Scanning probe
US7347855B2 (en) 2001-10-29 2008-03-25 Ultrashape Ltd. Non-invasive ultrasonic body contouring
US6920883B2 (en) 2001-11-08 2005-07-26 Arthrocare Corporation Methods and apparatus for skin treatment
US7115093B2 (en) 2001-11-21 2006-10-03 Ge Medical Systems Global Technology Company, Llc Method and system for PDA-based ultrasound system
US7317818B2 (en) 2001-11-26 2008-01-08 L'ORéAL S.A. Method of enabling an analysis of an external body portion
CN100401986C (en) 2001-11-30 2008-07-16 彼得罗·莫伊拉宁;帕特里克·尼科尔松;程蜀琳;龙西·蒂莫伦 A method and device for the non-invasive assessment of bones
US6554771B1 (en) 2001-12-18 2003-04-29 Koninklijke Philips Electronics N.V. Position sensor in ultrasound transducer probe
US6746402B2 (en) 2002-01-02 2004-06-08 E. Tuncay Ustuner Ultrasound system and method
JP2003204982A (en) 2002-01-09 2003-07-22 Byeong Gon Kim Abdomen warming and vibrating belt
EP1465701A4 (en) 2002-01-15 2008-08-13 Univ California System and method providing directional ultrasound therapy to skeletal joints
CN1615166B (en) 2002-01-15 2010-07-07 乌尔特拉佐尼克斯Dnt股份公司 Device for mini-invasive ultrasound treatment of an object by a heat-isolated transducer
KR20040081752A (en) 2002-01-21 2004-09-22 마츠시다 덴코 가부시키가이샤 Ultrasonic percutaneous permeating device, ultrasonic percutaneous permeating kit, and ultrasonic percutaneous permeating method
WO2003061756A3 (en) 2002-01-23 2003-10-16 Univ California Implantable thermal treatment method and apparatus
JP4363987B2 (en) 2002-01-29 2009-11-11 ヤング、スティーブン・マイケル・ラドリー Device for converging the ultrasonic vibration beams
EP1474690B1 (en) 2002-02-07 2010-10-13 Boehringer Ingelheim (Canada) Ltd. E2 displacement assay for identifying inhibitors of hpv
JP4265139B2 (en) 2002-02-18 2009-05-20 コニカミノルタホールディングス株式会社 The radiation image conversion panel and a radiation image reading apparatus
CA2476873A1 (en) 2002-02-20 2003-08-28 Liposonix, Inc. Ultrasonic treatment and imaging of adipose tissue
JP2003248097A (en) 2002-02-25 2003-09-05 Konica Corp Radiation image conversion panel and its production method
US6648839B2 (en) 2002-02-28 2003-11-18 Misonix, Incorporated Ultrasonic medical treatment device for RF cauterization and related method
US20030171701A1 (en) 2002-03-06 2003-09-11 Eilaz Babaev Ultrasonic method and device for lypolytic therapy
US6824516B2 (en) 2002-03-11 2004-11-30 Medsci Technologies, Inc. System for examining, mapping, diagnosing, and treating diseases of the prostate
US8840608B2 (en) 2002-03-15 2014-09-23 The General Hospital Corporation Methods and devices for selective disruption of fatty tissue by controlled cooling
EP1539081A4 (en) 2002-03-20 2009-05-13 Yoni Iger Method and apparatus for altering activity of tissue layers
US6662054B2 (en) 2002-03-26 2003-12-09 Syneron Medical Ltd. Method and system for treating skin
US7534211B2 (en) 2002-03-29 2009-05-19 Sonosite, Inc. Modular apparatus for diagnostic ultrasound
US6887239B2 (en) 2002-04-17 2005-05-03 Sontra Medical Inc. Preparation for transmission and reception of electrical signals
JP2003309890A (en) 2002-04-17 2003-10-31 Matsushita Electric Ind Co Ltd Ultrasonic probe
US7000126B2 (en) 2002-04-18 2006-02-14 Intel Corporation Method for media content presentation in consideration of system power
DE10219297A1 (en) 2002-04-25 2003-11-06 Laser & Med Tech Gmbh Medical instrument for generation of scar tissue to stiffen soft tissue, combines an ultrasound generator with a laser so that electromagnetic and or ultrasound energy can be coupled into the tissue via an opto-acoustic coupler
US20030236487A1 (en) 2002-04-29 2003-12-25 Knowlton Edward W. Method for treatment of tissue with feedback
DE10219217B3 (en) 2002-04-29 2004-02-12 Creative-Line Gmbh Object with picture built up from lines, e.g. for decoration, has line pattern eroded into main surface
US6992305B2 (en) 2002-05-08 2006-01-31 Konica Corporation Radiation image converting panel and production method of the same
US20030212129A1 (en) 2002-05-13 2003-11-13 Liu Kay Miyakawa System and method for revitalizing human skin
US6846290B2 (en) * 2002-05-14 2005-01-25 Riverside Research Institute Ultrasound method and system
US7359745B2 (en) 2002-05-15 2008-04-15 Case Western Reserve University Method to correct magnetic field/phase variations in proton resonance frequency shift thermometry in magnetic resonance imaging
US8376946B2 (en) 2002-05-16 2013-02-19 Barbara Ann Karamanos Cancer Institute Method and apparatus for combined diagnostic and therapeutic ultrasound system incorporating noninvasive thermometry, ablation control and automation
US7967839B2 (en) 2002-05-20 2011-06-28 Rocky Mountain Biosystems, Inc. Electromagnetic treatment of tissues and cells
US7179238B2 (en) 2002-05-21 2007-02-20 Medtronic Xomed, Inc. Apparatus and methods for directly displacing the partition between the middle ear and inner ear at an infrasonic frequency
US6958043B2 (en) 2002-05-21 2005-10-25 Medtronic Xomed, Inc. Apparatus and method for displacing the partition between the middle ear and the inner ear using a manually powered device
WO2003099382A1 (en) 2002-05-23 2003-12-04 Gendel Limited Ablation device
WO2003101530A3 (en) 2002-05-30 2004-04-08 Univ Washington Solid hydrogel coupling for ultrasound imaging and therapy
US20030233085A1 (en) 2002-06-18 2003-12-18 Pedro Giammarusti Optimization of transcutaneous active permeation of compounds through the synergistic use of ultrasonically generated mechanical abrasion of the skin, chemical enhancers and simultaneous application of sonophoresis, iontophoresis, electroporation, mechanical vibrations and magnetophoresis through single application devices
KR20050026404A (en) 2002-06-19 2005-03-15 팔로마 메디칼 테크놀로지스, 인코포레이티드 Method and apparatus for photothermal treatment of tissue at depth
KR100923717B1 (en) 2002-06-25 2009-10-27 울트라세이프 인코포레이티드 Devices and methodologies useful in body aesthetics
US20040001809A1 (en) 2002-06-26 2004-01-01 Pharmasonics, Inc. Methods and apparatus for enhancing a response to nucleic acid vaccines
US20040082859A1 (en) 2002-07-01 2004-04-29 Alan Schaer Method and apparatus employing ultrasound energy to treat body sphincters
US20040049134A1 (en) 2002-07-02 2004-03-11 Tosaya Carol A. System and methods for treatment of alzheimer's and other deposition-related disorders of the brain
KR100872242B1 (en) 2002-08-29 2008-12-05 엘지전자 주식회사 Computor of Portable composition type
JP3728283B2 (en) 2002-08-30 2005-12-21 キヤノン株式会社 Recording device
CN1494933A (en) 2002-09-09 2004-05-12 株式会社东芝 Ultrasonic radiation equipment
US7004940B2 (en) 2002-10-10 2006-02-28 Ethicon, Inc. Devices for performing thermal ablation having movable ultrasound transducers
US6669638B1 (en) 2002-10-10 2003-12-30 Koninklijke Philips Electronics N.V. Imaging ultrasound transducer temperature control system and method
US6709392B1 (en) 2002-10-10 2004-03-23 Koninklijke Philips Electronics N.V. Imaging ultrasound transducer temperature control system and method using feedback
US6921371B2 (en) 2002-10-14 2005-07-26 Ekos Corporation Ultrasound radiating members for catheter
US6860852B2 (en) 2002-10-25 2005-03-01 Compex Medical S.A. Ultrasound therapeutic device
JP2004147719A (en) 2002-10-29 2004-05-27 Toshiba Corp Ultrasonic wave irradiation apparatus
EP1573361A1 (en) 2002-11-06 2005-09-14 Philips Electronics N.V. Phased array acoustic system for 3d imaging of moving parts-----
US7676047B2 (en) 2002-12-03 2010-03-09 Bose Corporation Electroacoustical transducing with low frequency augmenting devices
US8088067B2 (en) 2002-12-23 2012-01-03 Insightec Ltd. Tissue aberration corrections in ultrasound therapy
US20040143297A1 (en) 2003-01-21 2004-07-22 Maynard Ramsey Advanced automatic external defibrillator powered by alternative and optionally multiple electrical power sources and a new business method for single use AED distribution and refurbishment
US7150716B2 (en) 2003-02-20 2006-12-19 Siemens Medical Solutions Usa, Inc. Measuring transducer movement methods and systems for multi-dimensional ultrasound imaging
US20030191396A1 (en) 2003-03-10 2003-10-09 Sanghvi Narendra T Tissue treatment method and apparatus
US6918907B2 (en) 2003-03-13 2005-07-19 Boston Scientific Scimed, Inc. Surface electrode multiple mode operation
RU2389471C2 (en) 2003-03-13 2010-05-20 Альфатек Медикал Системз Лтд. Ultrasonic cellulitis treatment
US6733449B1 (en) 2003-03-20 2004-05-11 Siemens Medical Solutions Usa, Inc. System and method for real-time streaming of ultrasound data to a diagnostic medical ultrasound streaming application
US20040189155A1 (en) 2003-03-27 2004-09-30 Olympus Corporation Ultrasonic transducer and ultrasonic motor
US20040206365A1 (en) 2003-03-31 2004-10-21 Knowlton Edward Wells Method for treatment of tissue
US9149322B2 (en) 2003-03-31 2015-10-06 Edward Wells Knowlton Method for treatment of tissue
EP1608267A4 (en) 2003-03-31 2007-04-25 Liposonix Inc Vortex transducer
EP1479412B1 (en) 2003-05-19 2008-10-22 UST Inc. Geometrically shaped coupling hydrogel standoffs for high intensity focused ultrasound
WO2004103183A3 (en) 2003-05-21 2005-05-06 Rene H Dietrich Ultrasound coupling medium for use in medical diagnostics
EP1480199A1 (en) 2003-05-22 2004-11-24 Esaote S.p.A. Method for optimization of transmitted and received ultrasound pulses, particularly for ultrasonic imaging
US6896657B2 (en) 2003-05-23 2005-05-24 Scimed Life Systems, Inc. Method and system for registering ultrasound image in three-dimensional coordinate system
JP4041014B2 (en) 2003-06-06 2008-01-30 オリンパス株式会社 Ultrasonic surgical device
US20080086056A1 (en) 2003-08-25 2008-04-10 Industrial Technology Research Institute Micro ultrasonic transducers
WO2004110279A9 (en) 2003-06-12 2005-06-23 Bracco Research Sa Blood flow estimates through replenishment curve fitting in ultrasound contrast imaging
JP4165562B2 (en) 2003-06-13 2008-10-15 松下電工株式会社 Ultrasonic wave applying skin care device
US7303555B2 (en) 2003-06-30 2007-12-04 Depuy Products, Inc. Imaging and therapeutic procedure for carpal tunnel syndrome
US20050033316A1 (en) 2003-07-14 2005-02-10 M. Glen Kertz Ultrasonic skin cleaner
US20050070961A1 (en) 2003-07-15 2005-03-31 Terumo Kabushiki Kaisha Energy treatment apparatus
WO2005011804A3 (en) 2003-07-31 2007-01-25 Peter D Costantino Ultasound treatment and imaging system
JP4472395B2 (en) 2003-08-07 2010-06-02 オリンパス株式会社 Ultrasonic surgical system
US7375455B2 (en) 2003-08-08 2008-05-20 Matsushita Electric Industrial Co., Ltd. Ultrasonic motor driving device and ultrasonic diagnosis apparatus
US7398116B2 (en) 2003-08-11 2008-07-08 Veran Medical Technologies, Inc. Methods, apparatuses, and systems useful in conducting image guided interventions
US7294125B2 (en) 2003-08-22 2007-11-13 Scimed Life Systems, Inc. Methods of delivering energy to body portions to produce a therapeutic response
US20050080469A1 (en) 2003-09-04 2005-04-14 Larson Eugene A. Treatment of cardiac arrhythmia utilizing ultrasound
US6945937B2 (en) 2003-09-08 2005-09-20 Board Of Trustees University Of Arkansas Ultrasound apparatus and method for augmented clot lysis
US20050055018A1 (en) 2003-09-08 2005-03-10 Michael Kreindel Method and device for sub-dermal tissue treatment
DE20314479U1 (en) 2003-09-13 2004-02-12 Peter Krauth Gmbh Low frequency ultrasound treatment unit for wet use has electronic unit with detachable connection to sealed titanium or stainless steel membrane ultrasound head
FR2859983B1 (en) 2003-09-22 2006-03-10 Valois Sas Fastening device and mounting method for fixing a dispensing member to an opening of tank
US20050074407A1 (en) 2003-10-01 2005-04-07 Sonotech, Inc. PVP and PVA as in vivo biocompatible acoustic coupling medium
US7332985B2 (en) 2003-10-30 2008-02-19 Avago Technologies Wireless Ip (Singapore) Pte Ltd. Cavity-less film bulk acoustic resonator (FBAR) devices
WO2005044129A3 (en) 2003-11-04 2006-02-16 Pierre D Mourad Toothbrush employing an acoustic waveguide
US20050113689A1 (en) 2003-11-21 2005-05-26 Arthur Gritzky Method and apparatus for performing multi-mode imaging
US20050137656A1 (en) 2003-12-23 2005-06-23 American Environmental Systems, Inc. Acoustic-optical therapeutical devices and methods
JP2007516810A (en) 2003-12-30 2007-06-28 ライポソニックス, インコーポレイテッド Ultrasound treatment head having an operating control
US8343051B2 (en) 2003-12-30 2013-01-01 Liposonix, Inc. Apparatus and methods for the destruction of adipose tissue
US20050154308A1 (en) 2003-12-30 2005-07-14 Liposonix, Inc. Disposable transducer seal
JP4722860B2 (en) 2003-12-30 2011-07-13 ライポソニックス, インコーポレイテッド System and method for the destruction of adipose tissue
US20050193451A1 (en) 2003-12-30 2005-09-01 Liposonix, Inc. Articulating arm for medical procedures
JP2007516809A (en) 2003-12-30 2007-06-28 ライポソニックス, インコーポレイテッド Ultrasonic transducer component
US7857773B2 (en) 2003-12-30 2010-12-28 Medicis Technologies Corporation Apparatus and methods for the destruction of adipose tissue
US8926533B2 (en) 2003-12-30 2015-01-06 Liposonix, Inc. Therapy head for use with an ultrasound system
CA2555396C (en) 2004-02-06 2016-03-15 Daniel Barolet Method and device for the treatment of mammalian tissues
EP1711109B1 (en) 2004-02-06 2013-05-08 Technion Research And Development Foundation Ltd. Localized production of microbubbles and control of cavitational and heating effects by use of enhanced ultrasound
JP2005245521A (en) 2004-03-01 2005-09-15 Japan Natural Laboratory Co Ltd Skin care or beauty system using ion introducer, ultrasonic wave facial treatment device, and cosmetic additives
WO2005083881A1 (en) 2004-03-02 2005-09-09 Murata Manufacturing Co., Ltd. Surface acoustic wave device
CA2559260C (en) 2004-03-12 2015-05-12 University Of Virginia Patent Foundation Electron transfer dissociation for biopolymer sequence analysis
US20050228281A1 (en) 2004-03-31 2005-10-13 Nefos Thomas P Handheld diagnostic ultrasound system with head mounted display
US20060020309A1 (en) 2004-04-09 2006-01-26 Palomar Medical Technologies, Inc. Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor
JP4100372B2 (en) 2004-05-10 2008-06-11 松下電工株式会社 Ultrasonic Beauty Equipment
US8235909B2 (en) 2004-05-12 2012-08-07 Guided Therapy Systems, L.L.C. Method and system for controlled scanning, imaging and/or therapy
US7951095B2 (en) 2004-05-20 2011-05-31 Ethicon Endo-Surgery, Inc. Ultrasound medical system
US7837675B2 (en) 2004-07-22 2010-11-23 Shaser, Inc. Method and device for skin treatment with replaceable photosensitive window
US7699780B2 (en) 2004-08-11 2010-04-20 Insightec—Image-Guided Treatment Ltd. Focused ultrasound system with adaptive anatomical aperture shaping
US7310928B2 (en) 2004-08-24 2007-12-25 Curry Janine V Retractable spurs
US7105986B2 (en) 2004-08-27 2006-09-12 General Electric Company Ultrasound transducer with enhanced thermal conductivity
US20070065420A1 (en) 2005-08-23 2007-03-22 Johnson Lanny L Ultrasound Therapy Resulting in Bone Marrow Rejuvenation
US7393325B2 (en) 2004-09-16 2008-07-01 Guided Therapy Systems, L.L.C. Method and system for ultrasound treatment with a multi-directional transducer
US7824348B2 (en) 2004-09-16 2010-11-02 Guided Therapy Systems, L.L.C. System and method for variable depth ultrasound treatment
US9011336B2 (en) 2004-09-16 2015-04-21 Guided Therapy Systems, Llc Method and system for combined energy therapy profile
EP1811901B1 (en) 2004-09-19 2009-04-29 Bioscan, Ltd. Intravascular ultrasound imaging device
US7530958B2 (en) 2004-09-24 2009-05-12 Guided Therapy Systems, Inc. Method and system for combined ultrasound treatment
US20150165243A1 (en) 2004-09-24 2015-06-18 Guided Therapy Systems, Llc System and Method for Treating Cartilage and Injuries to Joints and Connective Tissue
US8535228B2 (en) 2004-10-06 2013-09-17 Guided Therapy Systems, Llc Method and system for noninvasive face lifts and deep tissue tightening
US8690778B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Energy-based tissue tightening
DK1855759T3 (en) 2004-10-06 2017-06-06 Guided Therapy Systems Llc A system for ultrasonic treatment of tissue
US8444562B2 (en) 2004-10-06 2013-05-21 Guided Therapy Systems, Llc System and method for treating muscle, tendon, ligament and cartilage tissue
US20120046547A1 (en) 2004-10-06 2012-02-23 Guided Therapy Systems, Llc System and method for cosmetic treatment
US7758524B2 (en) 2004-10-06 2010-07-20 Guided Therapy Systems, L.L.C. Method and system for ultra-high frequency ultrasound treatment
US7530356B2 (en) 2004-10-06 2009-05-12 Guided Therapy Systems, Inc. Method and system for noninvasive mastopexy
KR20140013044A (en) 2004-10-06 2014-02-04 가이디드 테라피 시스템스, 엘.엘.씨. System for controlled thermal treatment of human superficial tissue
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
EP2279699A3 (en) 2004-10-06 2014-02-19 Guided Therapy Systems, L.L.C. Method and system for non-invasive cosmetic enhancement of cellulite
US20060079868A1 (en) 2004-10-07 2006-04-13 Guided Therapy Systems, L.L.C. Method and system for treatment of blood vessel disorders
US7235592B2 (en) 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
US20060111744A1 (en) 2004-10-13 2006-05-25 Guided Therapy Systems, L.L.C. Method and system for treatment of sweat glands
US20060089688A1 (en) 2004-10-25 2006-04-27 Dorin Panescu Method and apparatus to reduce wrinkles through application of radio frequency energy to nerves
US20060094988A1 (en) 2004-10-28 2006-05-04 Tosaya Carol A Ultrasonic apparatus and method for treating obesity or fat-deposits or for delivering cosmetic or other bodily therapy
US20060122509A1 (en) 2004-11-24 2006-06-08 Liposonix, Inc. System and methods for destroying adipose tissue
US20060116583A1 (en) 2004-11-26 2006-06-01 Yoichi Ogasawara Ultrasonic diagnostic apparatus and control method thereof
US8162858B2 (en) 2004-12-13 2012-04-24 Us Hifu, Llc Ultrasonic medical treatment device with variable focal zone
CN100542635C (en) 2005-01-10 2009-09-23 重庆海扶(Hifu)技术有限公司 High intensity focused ultrasound therapy device and method
US7553284B2 (en) 2005-02-02 2009-06-30 Vaitekunas Jeffrey J Focused ultrasound for pain reduction
US7918795B2 (en) 2005-02-02 2011-04-05 Gynesonics, Inc. Method and device for uterine fibroid treatment
JP2008529580A (en) 2005-02-06 2008-08-07 ウルトラシェイプ エルティーディー. Non-thermal waves organization reformed
US20060241440A1 (en) 2005-02-07 2006-10-26 Yoram Eshel Non-thermal acoustic tissue modification
US7537240B2 (en) 2005-02-22 2009-05-26 Automotive Systems Laboratory, Inc. Gas generating system
US7771418B2 (en) 2005-03-09 2010-08-10 Sunnybrook Health Sciences Centre Treatment of diseased tissue using controlled ultrasonic heating
US7931611B2 (en) 2005-03-23 2011-04-26 Misonix, Incorporated Ultrasonic wound debrider probe and method of use
US7335997B2 (en) 2005-03-31 2008-02-26 Ethicon Endo-Surgery, Inc. System for controlling ultrasonic clamping and cutting instruments
JP4695188B2 (en) 2005-04-25 2011-06-08 アーデント サウンド, インコーポレイテッド Method and apparatus for improving the safety of the computer peripherals
US7330578B2 (en) 2005-06-23 2008-02-12 Accuray Inc. DRR generation and enhancement using a dedicated graphics device
US7785277B2 (en) 2005-06-23 2010-08-31 Celleration, Inc. Removable applicator nozzle for ultrasound wound therapy device
WO2007013814A3 (en) 2005-07-26 2007-07-26 Bjoern A J Angelsen Dual frequency band ultrasound transducer arrays
US7955262B2 (en) 2005-07-26 2011-06-07 Syneron Medical Ltd. Method and apparatus for treatment of skin using RF and ultrasound energies
US8182428B2 (en) 2005-07-26 2012-05-22 Surf Technology As Dual frequency band ultrasound transducer arrays
WO2007019365B1 (en) 2005-08-03 2007-11-29 Massachusetts Eye & Ear Infirm Targeted muscle ablation for reducing signs of aging
US7621873B2 (en) 2005-08-17 2009-11-24 University Of Washington Method and system to synchronize acoustic therapy with ultrasound imaging
US7517315B2 (en) 2005-08-26 2009-04-14 Boston Scientific Scimed, Inc. System and method for determining the proximity between a medical probe and a tissue surface
US8057408B2 (en) 2005-09-22 2011-11-15 The Regents Of The University Of Michigan Pulsed cavitational ultrasound therapy
US20070083120A1 (en) 2005-09-22 2007-04-12 Cain Charles A Pulsed cavitational ultrasound therapy
JP2009510889A (en) 2005-09-27 2009-03-12 株式会社 メディソンMedison Co.,Ltd. The ultrasonic diagnostic system used for the probe and this ultrasonic diagnostic
US20070088346A1 (en) 2005-10-14 2007-04-19 Mirizzi Michael S Method and apparatus for varicose vein treatment using acoustic hemostasis
WO2007047726B1 (en) 2005-10-20 2007-09-13 Gen Hospital Corp Non-invasive treatment of fascia
CN101299968A (en) 2005-11-07 2008-11-05 西格诺斯蒂克斯有限公司 Ultrasound measurement system and method
DE102005053918A1 (en) 2005-11-11 2007-05-16 Zimmer Elektromedizin Gmbh Method and device for irradiating ultrasound into tissue
US20120046553A9 (en) 2007-01-18 2012-02-23 General Electric Company Ultrasound catheter housing with electromagnetic shielding properties and methods of manufacture
US8287337B2 (en) 2006-01-11 2012-10-16 Hcr Incorporated Cold storage doorway with airflow control system and method
US9017717B2 (en) 2006-01-16 2015-04-28 Peach Technologies Llc Bandage for facilitating transdermal respiration and healing
CN101505674B (en) 2006-01-17 2014-03-05 恩迪梅德医疗有限公司 Electrosurgical methods and devices employing phase-controlled radiofrequency energy
US8133191B2 (en) 2006-02-16 2012-03-13 Syneron Medical Ltd. Method and apparatus for treatment of adipose tissue
US20090048514A1 (en) 2006-03-09 2009-02-19 Slender Medical Ltd. Device for ultrasound monitored tissue treatment
US9107798B2 (en) 2006-03-09 2015-08-18 Slender Medical Ltd. Method and system for lipolysis and body contouring
US7828734B2 (en) 2006-03-09 2010-11-09 Slender Medical Ltd. Device for ultrasound monitored tissue treatment
US20070213696A1 (en) 2006-03-10 2007-09-13 Palomar Medical Technologies, Inc. Photocosmetic device
US8920320B2 (en) 2006-03-10 2014-12-30 Liposonix, Inc. Methods and apparatus for coupling a HIFU transducer to a skin surface
US20070219604A1 (en) 2006-03-20 2007-09-20 Palomar Medical Technologies, Inc. Treatment of tissue with radiant energy
WO2007113161A1 (en) 2006-03-30 2007-10-11 Massimo Santangelo Method and equipment to induce osteogenesis in a bone region of a patient
US20070239079A1 (en) 2006-04-07 2007-10-11 The General Hospital Corporation Method and apparatus for selective treatment of biological tissue using ultrasound energy
JP3123559U (en) 2006-05-10 2006-07-20 ニチハ株式会社 Cosmetic corner material
US20070264625A1 (en) 2006-05-11 2007-11-15 Reliant Technologies, Inc. Apparatus and Method for Ablation-Related Dermatological Treatment of Selected Targets
US20080039724A1 (en) 2006-08-10 2008-02-14 Ralf Seip Ultrasound transducer with improved imaging
US20080195000A1 (en) 2006-09-06 2008-08-14 Spooner Gregory J R System and Method for Dermatological Treatment Using Ultrasound
US20080183110A1 (en) 2006-09-06 2008-07-31 Davenport Scott A Ultrasound system and method for hair removal
US7955281B2 (en) 2006-09-07 2011-06-07 Nivasonix, Llc External ultrasound lipoplasty
US8262591B2 (en) 2006-09-07 2012-09-11 Nivasonix, Llc External ultrasound lipoplasty
US9566454B2 (en) 2006-09-18 2017-02-14 Guided Therapy Systems, Llc Method and sysem for non-ablative acne treatment and prevention
WO2008036773A1 (en) 2006-09-19 2008-03-27 Guided Therapy Systems, Llc Method and system for treating muscle, tendon, ligament and cartilage tissue
US9241683B2 (en) 2006-10-04 2016-01-26 Ardent Sound Inc. Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid
US20080183077A1 (en) 2006-10-19 2008-07-31 Siemens Corporate Research, Inc. High intensity focused ultrasound path determination
CN101536547B (en) 2006-11-08 2013-05-22 株式会社日立医药 Ultrasonic probe and ultrasonographic device using the same
US8656783B2 (en) 2006-11-10 2014-02-25 Siemens Medical Solutions Usa, Inc. Transducer array imaging system
US9492686B2 (en) 2006-12-04 2016-11-15 Koninklijke Philips N.V. Devices and methods for treatment of skin conditions
US8382689B2 (en) 2007-02-08 2013-02-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Device and method for high intensity focused ultrasound ablation with acoustic lens
US9706976B2 (en) 2007-02-08 2017-07-18 Siemens Medical Solutions Usa, Inc. Ultrasound imaging systems and methods of performing ultrasound procedures
US8231533B2 (en) 2007-02-16 2012-07-31 Buchalter Neal Ultrasound coupling device
EP1970059B1 (en) 2007-03-12 2009-11-25 DOBAVET GmbH Medication with Dobesilat-Calcium for treatment and prophylaxis of tendon disease
EP2139560B1 (en) 2007-03-19 2012-05-30 Syneron Medical Ltd. Device for soft tissue destruction
US8142200B2 (en) 2007-03-26 2012-03-27 Liposonix, Inc. Slip ring spacer and method for its use
EP2142129A4 (en) 2007-04-19 2011-04-20 Miramar Labs Inc Methods and apparatus for reducing sweat production
US20090012394A1 (en) 2007-04-30 2009-01-08 General Electric Company User interface for ultrasound system
JP5975600B2 (en) 2007-05-07 2016-08-24 ガイデッド セラピー システムズ, エル.エル.シー. Method and system for combining the acoustic energy using a coupler member, and collected at the focal
US20150174388A1 (en) 2007-05-07 2015-06-25 Guided Therapy Systems, Llc Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue
US9216276B2 (en) 2007-05-07 2015-12-22 Guided Therapy Systems, Llc Methods and systems for modulating medicants using acoustic energy
EP2164396A2 (en) 2007-06-01 2010-03-24 Philips Electronics N.V. Light weight wireless ultrasound probe
WO2009009786A3 (en) 2007-07-12 2010-01-28 Board Of Regents, The University Of Texas System Magneto-motive ultrasound detection of magnetic nanoparticles
CN101784236A (en) 2007-07-26 2010-07-21 赛诺龙医疗公司 A method and apparatus for ultrasound tissue treatment
EP2175792A4 (en) 2007-08-10 2011-07-06 Eleme Medical Inc Multi-module skin or body treatment device and the method of using
US8235902B2 (en) 2007-09-11 2012-08-07 Focus Surgery, Inc. System and method for tissue change monitoring during HIFU treatment
WO2009043046A1 (en) 2007-09-28 2009-04-02 Nivasonix, Llc Handheld transducer scanning speed guides and position detectors
WO2009048969A1 (en) 2007-10-09 2009-04-16 Cabochon Aesthetics, Inc. Ultrasound apparatus with treatment lens
US20100274161A1 (en) 2007-10-15 2010-10-28 Slender Medical, Ltd. Implosion techniques for ultrasound
EP2230904A4 (en) 2007-12-06 2014-05-21 Measurement Spec Inc Multilayer backing absorber for ultrasonic transducer
US20090177123A1 (en) 2007-12-28 2009-07-09 Celleration, Inc. Methods for treating inflammatory disorders
EP2231279A1 (en) 2007-12-28 2010-09-29 Celleration, Inc. Methods for treating inflammatory skin disorders
US8461108B2 (en) 2008-03-07 2013-06-11 Myoscience, Inc. Subdermal tissue remodeling using myostatin, methods and related systems
DK2282675T3 (en) 2008-06-06 2016-05-17 Ulthera Inc System for the cosmetic treatment and imaging
US20090312693A1 (en) 2008-06-13 2009-12-17 Vytronus, Inc. System and method for delivering energy to tissue
US20100022919A1 (en) 2008-07-22 2010-01-28 Celleration, Inc. Methods of Skin Grafting Using Ultrasound
US20100042020A1 (en) 2008-08-13 2010-02-18 Shmuel Ben-Ezra Focused energy delivery apparatus method and system
US20100113983A1 (en) 2008-10-31 2010-05-06 Microsoft Corporation Utilizing ultrasound to disrupt pathogens
US20100130891A1 (en) 2008-11-21 2010-05-27 Taggart Rebecca M Wearable Therapeutic Ultrasound Article
US8585618B2 (en) 2008-12-22 2013-11-19 Cutera, Inc. Broad-area irradiation of small near-field targets using ultrasound
KR20110101204A (en) 2008-12-24 2011-09-15 가이디드 테라피 시스템스, 엘.엘.씨. Methods and systems for fat reduction and/or cellulite treatment
US20100191120A1 (en) 2009-01-28 2010-07-29 General Electric Company Apparatus and method for controlling an ultrasound system based on contact with an ultrasound probe
CN102548615A (en) 2009-03-04 2012-07-04 利普索尼克斯股份有限公司 Ultrasonic treatment of adipose tissue at multiple depths
US7905007B2 (en) 2009-03-18 2011-03-15 General Electric Company Method for forming a matching layer structure of an acoustic stack
US20100286518A1 (en) 2009-05-11 2010-11-11 General Electric Company Ultrasound system and method to deliver therapy based on user defined treatment spaces
US8348966B2 (en) 2009-08-07 2013-01-08 Thayer Intellectual Property, Inc. Systems and methods for treatment of compressed nerves
EP2467062B1 (en) 2009-08-17 2017-01-18 Histosonics, Inc. Disposable acoustic coupling medium container
US8264126B2 (en) 2009-09-01 2012-09-11 Measurement Specialties, Inc. Multilayer acoustic impedance converter for ultrasonic transducers
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
US20110190745A1 (en) 2009-12-04 2011-08-04 Uebelhoer Nathan S Treatment of sweat glands
US20130096471A1 (en) 2010-08-02 2013-04-18 Guided Therapy Systems, Llc Systems and methods for treating injuries to joints and connective tissue
KR20140047709A (en) 2011-07-11 2014-04-22 가이디드 테라피 시스템스, 엘.엘.씨. Systems and methods for coupling an ultrasound source to tissue
WO2012018391A3 (en) 2010-08-02 2012-07-05 Guided Therapy Systems, Llc Methods and systems for treating plantar fascia
US9504446B2 (en) 2010-08-02 2016-11-29 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
US8857438B2 (en) 2010-11-08 2014-10-14 Ulthera, Inc. Devices and methods for acoustic shielding
US20120191020A1 (en) 2011-01-25 2012-07-26 Shuki Vitek Uniform thermal treatment of tissue interfaces
US20120296240A1 (en) 2011-05-20 2012-11-22 Slender Medical Ltd. Ultrasound eye bag treatment
US8752467B2 (en) 2011-06-30 2014-06-17 Elwha Llc Wearable air blast protection device having at least two attenuating regions
US8858471B2 (en) 2011-07-10 2014-10-14 Guided Therapy Systems, Llc Methods and systems for ultrasound treatment
US20130066237A1 (en) 2011-09-09 2013-03-14 Palomar Medical Technologies, Inc. Methods and devices for inflammation treatment
US9510802B2 (en) 2012-09-21 2016-12-06 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
US8686335B2 (en) 2011-12-31 2014-04-01 Seno Medical Instruments, Inc. System and method for adjusting the light output of an optoacoustic imaging system
US8836203B2 (en) 2012-03-30 2014-09-16 Measurement Specialties, Inc. Signal return for ultrasonic transducers
US9263663B2 (en) 2012-04-13 2016-02-16 Ardent Sound, Inc. Method of making thick film transducer arrays
US20130338475A1 (en) 2012-06-13 2013-12-19 Seno Medical Instruments, Inc. Optoacoustic imaging system with fiber optic cable
WO2014055708A1 (en) 2012-10-02 2014-04-10 Ardent Sound, Inc. Motion mechanisms for ultrasound transducer modules
CN204637350U (en) 2013-03-08 2015-09-16 奥赛拉公司 System for aesthstic formation of image is with processing system , many focuses processing system and carry out cosmetic process
US20150164734A1 (en) 2013-12-12 2015-06-18 Guided Therapy Systems, Llc System and Method for Cosmetic Enhancement of Lips
EP3079769A1 (en) 2013-12-13 2016-10-19 Guided Therapy Systems, L.L.C. System and method for non-invasive treatment with improved efficiency

Patent Citations (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039312A (en) * 1972-07-04 1977-08-02 Marcel Joseph Gaston Patru Bacteriostatic, fungistatic and algicidal compositions, particularly for submarine paints
US3913386A (en) * 1973-01-16 1975-10-21 Commissariat Energie Atomique Method of compensation for the angle of refraction of an ultrasonic beam and a device for the application of said method
US3992925A (en) * 1973-12-10 1976-11-23 U.S. Philips Corporation Device for ultrasonic scanning
US3965455A (en) * 1974-04-25 1976-06-22 The United States Of America As Represented By The Secretary Of The Navy Focused arc beam transducer-reflector
US4059098A (en) * 1975-07-21 1977-11-22 Stanford Research Institute Flexible ultrasound coupling system
US4101795A (en) * 1976-10-25 1978-07-18 Matsushita Electric Industrial Company Ultrasonic probe
US4213344A (en) * 1978-10-16 1980-07-22 Krautkramer-Branson, Incorporated Method and apparatus for providing dynamic focussing and beam steering in an ultrasonic apparatus
US4276491A (en) * 1979-10-02 1981-06-30 Ausonics Pty. Limited Focusing piezoelectric ultrasonic medical diagnostic system
US4343301A (en) * 1979-10-04 1982-08-10 Robert Indech Subcutaneous neural stimulation or local tissue destruction
US4325381A (en) * 1979-11-21 1982-04-20 New York Institute Of Technology Ultrasonic scanning head with reduced geometrical distortion
US4315514A (en) * 1980-05-08 1982-02-16 William Drewes Method and apparatus for selective cell destruction
US4381787A (en) * 1980-08-15 1983-05-03 Technicare Corporation Ultrasound imaging system combining static B-scan and real-time sector scanning capability
US4484569A (en) * 1981-03-13 1984-11-27 Riverside Research Institute Ultrasonic diagnostic and therapeutic transducer assembly and method for using
US4381007A (en) * 1981-04-30 1983-04-26 The United States Of America As Represented By The United States Department Of Energy Multipolar corneal-shaping electrode with flexible removable skirt
US4586512A (en) * 1981-06-26 1986-05-06 Thomson-Csf Device for localized heating of biological tissues
US4409839A (en) * 1981-07-01 1983-10-18 Siemens Ag Ultrasound camera
US4397314A (en) * 1981-08-03 1983-08-09 Clini-Therm Corporation Method and apparatus for controlling and optimizing the heating pattern for a hyperthermia system
US4441486A (en) * 1981-10-27 1984-04-10 Board Of Trustees Of Leland Stanford Jr. University Hyperthermia system
US4528979A (en) * 1982-03-18 1985-07-16 Kievsky Nauchno-Issledovatelsky Institut Otolaringologii Imeni Professora A.S. Kolomiiobenka Cryo-ultrasonic surgical instrument
US4452084A (en) * 1982-10-25 1984-06-05 Sri International Inherent delay line ultrasonic transducer and systems
US4646756A (en) * 1982-10-26 1987-03-03 The University Of Aberdeen Ultra sound hyperthermia device
US4513749A (en) * 1982-11-18 1985-04-30 Board Of Trustees Of Leland Stanford University Three-dimensional temperature probe
US4527550A (en) * 1983-01-28 1985-07-09 The United States Of America As Represented By The Department Of Health And Human Services Helical coil for diathermy apparatus
US4668516A (en) * 1983-03-30 1987-05-26 Alain Duraffourd Composition for regenerating the collagen of connective skin tissue and a process for its preparation
US4601296A (en) * 1983-10-07 1986-07-22 Yeda Research And Development Co., Ltd. Hyperthermia apparatus
US5150711A (en) * 1983-12-14 1992-09-29 Edap International, S.A. Ultra-high-speed extracorporeal ultrasound hyperthermia treatment device
US5143074A (en) * 1983-12-14 1992-09-01 Edap International Ultrasonic treatment device using a focussing and oscillating piezoelectric element
US4567895A (en) * 1984-04-02 1986-02-04 Advanced Technology Laboratories, Inc. Fully wetted mechanical ultrasound scanhead
US4697588A (en) * 1984-12-27 1987-10-06 Siemens Aktiengesellschaft Shock wave tube for the fragmentation of concrements
US4757820A (en) * 1985-03-15 1988-07-19 Kabushiki Kaisha Toshiba Ultrasound therapy system
US4663358A (en) * 1985-05-01 1987-05-05 Biomaterials Universe, Inc. Porous and transparent poly(vinyl alcohol) gel and method of manufacturing the same
US4865042A (en) * 1985-08-16 1989-09-12 Hitachi, Ltd. Ultrasonic irradiation system
US5304169A (en) * 1985-09-27 1994-04-19 Laser Biotech, Inc. Method for collagen shrinkage
US4874562A (en) * 1986-02-13 1989-10-17 Biomaterials Universe, Inc. Method of molding a polyvinyl alcohol contact lens
US4958626A (en) * 1986-04-22 1990-09-25 Nippon Oil Co., Ltd. Method for applying electromagnetic wave and ultrasonic wave therapies
US4875487A (en) * 1986-05-02 1989-10-24 Varian Associates, Inc. Compressional wave hyperthermia treating method and apparatus
US4807633A (en) * 1986-05-21 1989-02-28 Indianapolis Center For Advanced Research Non-invasive tissue thermometry system and method
US4867169A (en) * 1986-07-29 1989-09-19 Kaoru Machida Attachment attached to ultrasound probe for clinical application
US4865041A (en) * 1987-02-04 1989-09-12 Siemens Aktiengesellschaft Lithotripter having an ultrasound locating system integrated therewith
US4979501A (en) * 1987-05-19 1990-12-25 Vissh Voennomedicinski Institut Method and apparatus for medical treatment of the pathological state of bones
US5230338A (en) * 1987-11-10 1993-07-27 Allen George S Interactive image-guided surgical system for displaying images corresponding to the placement of a surgical tool or the like
US4860732A (en) * 1987-11-25 1989-08-29 Olympus Optical Co., Ltd. Endoscope apparatus provided with endoscope insertion aid
US4917096A (en) * 1987-11-25 1990-04-17 Laboratory Equipment, Corp. Portable ultrasonic probe
US5163421A (en) * 1988-01-22 1992-11-17 Angiosonics, Inc. In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging
US5143063A (en) * 1988-02-09 1992-09-01 Fellner Donald G Method of removing adipose tissue from the body
US4955365A (en) * 1988-03-02 1990-09-11 Laboratory Equipment, Corp. Localization and therapy system for treatment of spatially oriented focal disease
US4951653A (en) * 1988-03-02 1990-08-28 Laboratory Equipment, Corp. Ultrasound brain lesioning system
US4858613A (en) * 1988-03-02 1989-08-22 Laboratory Equipment, Corp. Localization and therapy system for treatment of spatially oriented focal disease
US5036855A (en) * 1988-03-02 1991-08-06 Laboratory Equipment, Corp. Localization and therapy system for treatment of spatially oriented focal disease
US5054470A (en) * 1988-03-02 1991-10-08 Laboratory Equipment, Corp. Ultrasonic treatment transducer with pressurized acoustic coupling
US4947046A (en) * 1988-05-27 1990-08-07 Konica Corporation Method for preparation of radiographic image conversion panel and radiographic image conversion panel thereby
US4938216A (en) * 1988-06-21 1990-07-03 Massachusetts Institute Of Technology Mechanically scanned line-focus ultrasound hyperthermia system
US4938217A (en) * 1988-06-21 1990-07-03 Massachusetts Institute Of Technology Electronically-controlled variable focus ultrasound hyperthermia system
US4893624A (en) * 1988-06-21 1990-01-16 Massachusetts Institute Of Technology Diffuse focus ultrasound hyperthermia system
US5265614A (en) * 1988-08-30 1993-11-30 Fujitsu Limited Acoustic coupler
US4976709A (en) * 1988-12-15 1990-12-11 Sand Bruce J Method for collagen treatment
US5123418A (en) * 1989-02-28 1992-06-23 Centre National De La Recherche Scientifique-C.N.R.S Micro-echographic probe for ultrasound collimation through a deformable surface
US5282797A (en) * 1989-05-30 1994-02-01 Cyrus Chess Method for treating cutaneous vascular lesions
US5435311A (en) * 1989-06-27 1995-07-25 Hitachi, Ltd. Ultrasound therapeutic system
US5115814A (en) * 1989-08-18 1992-05-26 Intertherapy, Inc. Intravascular ultrasonic imaging probe and methods of using same
US4973096A (en) * 1989-08-21 1990-11-27 Joyce Patrick H Shoe transporting device
US5158536A (en) * 1989-08-28 1992-10-27 Biopulmonics, Inc. Lung cancer hyperthermia via ultrasound and/or convection with perfiuorochemical liquids
US5156144A (en) * 1989-10-20 1992-10-20 Olympus Optical Co., Ltd. Ultrasonic wave therapeutic device
US5209720A (en) * 1989-12-22 1993-05-11 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
US5012797A (en) * 1990-01-08 1991-05-07 Montefiore Hospital Association Of Western Pennsylvania Method for removing skin wrinkles
US5191880A (en) * 1990-07-31 1993-03-09 Mcleod Kenneth J Method for the promotion of growth, ingrowth and healing of bone tissue and the prevention of osteopenia by mechanical loading of the bone tissue
US5117832A (en) * 1990-09-21 1992-06-02 Diasonics, Inc. Curved rectangular/elliptical transducer
US5150714A (en) * 1991-05-10 1992-09-29 Sri International Ultrasonic inspection method and apparatus with audible output
US5224467A (en) * 1991-10-30 1993-07-06 Kabushiki Kaisha Machida Seisakusho Endoscope with direction indication mechanism
US5524620A (en) * 1991-11-12 1996-06-11 November Technologies Ltd. Ablation of blood thrombi by means of acoustic energy
US5230334A (en) * 1992-01-22 1993-07-27 Summit Technology, Inc. Method and apparatus for generating localized hyperthermia
US5269297A (en) * 1992-02-27 1993-12-14 Angiosonics Inc. Ultrasonic transmission apparatus
US5501655A (en) * 1992-03-31 1996-03-26 Massachusetts Institute Of Technology Apparatus and method for acoustic heat generation and hyperthermia
US5295484A (en) * 1992-05-19 1994-03-22 Arizona Board Of Regents For And On Behalf Of The University Of Arizona Apparatus and method for intra-cardiac ablation of arrhythmias
US5321520A (en) * 1992-07-20 1994-06-14 Automated Medical Access Corporation Automated high definition/resolution image storage, retrieval and transmission system
US5370121A (en) * 1992-09-07 1994-12-06 Siemens Aktiengesellschaft Method and apparatus for non-invasive measurement of a temperature change in a subject
US5360268A (en) * 1992-11-02 1994-11-01 Nippon Soken Inc. Ultrasonic temperature measuring apparatus
US5419327A (en) * 1992-12-07 1995-05-30 Siemens Aktiengesellschaft Acoustic therapy means
US5267985A (en) * 1993-02-11 1993-12-07 Trancell, Inc. Drug delivery by multiple frequency phonophoresis
US5460595A (en) * 1993-06-01 1995-10-24 Dynatronics Laser Corporation Multi-frequency ultrasound therapy systems and methods
US5526812A (en) * 1993-06-21 1996-06-18 General Electric Company Display system for enhancing visualization of body structures during medical procedures
US5503320A (en) * 1993-08-19 1996-04-02 United States Surgical Corporation Surgical apparatus with indicator
US5380280A (en) * 1993-11-12 1995-01-10 Peterson; Erik W. Aspiration system having pressure-controlled and flow-controlled modes
US5371483A (en) * 1993-12-20 1994-12-06 Bhardwaj; Mahesh C. High intensity guided ultrasound source
US5507790A (en) * 1994-03-21 1996-04-16 Weiss; William V. Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism
US5471488A (en) * 1994-04-05 1995-11-28 International Business Machines Corporation Clock fault detection circuit
US5492126A (en) * 1994-05-02 1996-02-20 Focal Surgery Probe for medical imaging and therapy using ultrasound
US5524624A (en) * 1994-05-05 1996-06-11 Amei Technologies Inc. Apparatus and method for stimulating tissue growth with ultrasound
US5458596A (en) * 1994-05-06 1995-10-17 Dorsal Orthopedic Corporation Method and apparatus for controlled contraction of soft tissue
US5522869A (en) * 1994-05-17 1996-06-04 Burdette; Everette C. Ultrasound device for use in a thermotherapy apparatus
US5496256A (en) * 1994-06-09 1996-03-05 Sonex International Corporation Ultrasonic bone healing device for dental application
US5487388A (en) * 1994-11-01 1996-01-30 Interspec. Inc. Three dimensional ultrasonic scanning devices and techniques
US5520188A (en) * 1994-11-02 1996-05-28 Focus Surgery Inc. Annular array transducer
US6623430B1 (en) * 1997-10-14 2003-09-23 Guided Therapy Systems, Inc. Method and apparatus for safety delivering medicants to a region of tissue using imaging, therapy and temperature monitoring ultrasonic system
US6315741B1 (en) * 1997-10-31 2001-11-13 Roy W. Martin Method and apparatus for medical procedures using high-intensity focused ultrasound
US6413254B1 (en) * 2000-01-19 2002-07-02 Medtronic Xomed, Inc. Method of tongue reduction by thermal ablation using high intensity focused ultrasound
US20030176790A1 (en) * 2000-12-28 2003-09-18 Guided Therapy Systems, Inc. Visual imaging system for ultrasonic probe
US20040267252A1 (en) * 2003-06-30 2004-12-30 Ethicon, Inc. Multi-modality ablation device
US20050154332A1 (en) * 2004-01-12 2005-07-14 Onda Methods and systems for removing hair using focused acoustic energy

Cited By (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8073550B1 (en) 1997-07-31 2011-12-06 Miramar Labs, Inc. Method and apparatus for treating subcutaneous histological features
US8853600B2 (en) 1997-07-31 2014-10-07 Miramar Labs, Inc. Method and apparatus for treating subcutaneous histological features
US8480585B2 (en) 1997-10-14 2013-07-09 Guided Therapy Systems, Llc Imaging, therapy and temperature monitoring ultrasonic system and method
US9272162B2 (en) 1997-10-14 2016-03-01 Guided Therapy Systems, Llc Imaging, therapy, and temperature monitoring ultrasonic method
US8409097B2 (en) 2000-12-28 2013-04-02 Ardent Sound, Inc Visual imaging system for ultrasonic probe
US9907535B2 (en) 2000-12-28 2018-03-06 Ardent Sound, Inc. Visual imaging system for ultrasonic probe
US8235909B2 (en) 2004-05-12 2012-08-07 Guided Therapy Systems, L.L.C. Method and system for controlled scanning, imaging and/or therapy
US9011336B2 (en) 2004-09-16 2015-04-21 Guided Therapy Systems, Llc Method and system for combined energy therapy profile
US8708935B2 (en) 2004-09-16 2014-04-29 Guided Therapy Systems, Llc System and method for variable depth ultrasound treatment
US9114247B2 (en) 2004-09-16 2015-08-25 Guided Therapy Systems, Llc Method and system for ultrasound treatment with a multi-directional transducer
US7824348B2 (en) 2004-09-16 2010-11-02 Guided Therapy Systems, L.L.C. System and method for variable depth ultrasound treatment
US9095697B2 (en) 2004-09-24 2015-08-04 Guided Therapy Systems, Llc Methods for preheating tissue for cosmetic treatment of the face and body
US9895560B2 (en) 2004-09-24 2018-02-20 Guided Therapy Systems, Llc Methods for rejuvenating skin by heating tissue for cosmetic treatment of the face and body
US9827450B2 (en) 2004-10-06 2017-11-28 Guided Therapy Systems, L.L.C. System and method for fat and cellulite reduction
US9533175B2 (en) 2004-10-06 2017-01-03 Guided Therapy Systems, Llc Energy based fat reduction
US8066641B2 (en) 2004-10-06 2011-11-29 Guided Therapy Systems, L.L.C. Method and system for treating photoaged tissue
US9694212B2 (en) 2004-10-06 2017-07-04 Guided Therapy Systems, Llc Method and system for ultrasound treatment of skin
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
US9522290B2 (en) 2004-10-06 2016-12-20 Guided Therapy Systems, Llc System and method for fat and cellulite reduction
US8915870B2 (en) 2004-10-06 2014-12-23 Guided Therapy Systems, Llc Method and system for treating stretch marks
US9694211B2 (en) 2004-10-06 2017-07-04 Guided Therapy Systems, L.L.C. Systems for treating skin laxity
US9700340B2 (en) 2004-10-06 2017-07-11 Guided Therapy Systems, Llc System and method for ultra-high frequency ultrasound treatment
US9440096B2 (en) 2004-10-06 2016-09-13 Guided Therapy Systems, Llc Method and system for treating stretch marks
US8333700B1 (en) 2004-10-06 2012-12-18 Guided Therapy Systems, L.L.C. Methods for treatment of hyperhidrosis
US8366622B2 (en) 2004-10-06 2013-02-05 Guided Therapy Systems, Llc Treatment of sub-dermal regions for cosmetic effects
US9427601B2 (en) 2004-10-06 2016-08-30 Guided Therapy Systems, Llc Methods for face and neck lifts
US9427600B2 (en) 2004-10-06 2016-08-30 Guided Therapy Systems, L.L.C. Systems for treating skin laxity
US7758524B2 (en) 2004-10-06 2010-07-20 Guided Therapy Systems, L.L.C. Method and system for ultra-high frequency ultrasound treatment
US9421029B2 (en) 2004-10-06 2016-08-23 Guided Therapy Systems, Llc Energy based hyperhidrosis treatment
US9320537B2 (en) 2004-10-06 2016-04-26 Guided Therapy Systems, Llc Methods for noninvasive skin tightening
US8444562B2 (en) 2004-10-06 2013-05-21 Guided Therapy Systems, Llc System and method for treating muscle, tendon, ligament and cartilage tissue
US8460193B2 (en) 2004-10-06 2013-06-11 Guided Therapy Systems Llc System and method for ultra-high frequency ultrasound treatment
US9283410B2 (en) 2004-10-06 2016-03-15 Guided Therapy Systems, L.L.C. System and method for fat and cellulite reduction
US8282554B2 (en) 2004-10-06 2012-10-09 Guided Therapy Systems, Llc Methods for treatment of sweat glands
US8506486B2 (en) 2004-10-06 2013-08-13 Guided Therapy Systems, Llc Ultrasound treatment of sub-dermal tissue for cosmetic effects
US8523775B2 (en) 2004-10-06 2013-09-03 Guided Therapy Systems, Llc Energy based hyperhidrosis treatment
US9707412B2 (en) 2004-10-06 2017-07-18 Guided Therapy Systems, Llc System and method for fat and cellulite reduction
US8535228B2 (en) 2004-10-06 2013-09-17 Guided Therapy Systems, Llc Method and system for noninvasive face lifts and deep tissue tightening
US9713731B2 (en) 2004-10-06 2017-07-25 Guided Therapy Systems, Llc Energy based fat reduction
US9039619B2 (en) 2004-10-06 2015-05-26 Guided Therapy Systems, L.L.C. Methods for treating skin laxity
US9827449B2 (en) 2004-10-06 2017-11-28 Guided Therapy Systems, L.L.C. Systems for treating skin laxity
US8636665B2 (en) 2004-10-06 2014-01-28 Guided Therapy Systems, Llc Method and system for ultrasound treatment of fat
US8641622B2 (en) 2004-10-06 2014-02-04 Guided Therapy Systems, Llc Method and system for treating photoaged tissue
US8663112B2 (en) 2004-10-06 2014-03-04 Guided Therapy Systems, Llc Methods and systems for fat reduction and/or cellulite treatment
US8672848B2 (en) 2004-10-06 2014-03-18 Guided Therapy Systems, Llc Method and system for treating cellulite
US8932224B2 (en) 2004-10-06 2015-01-13 Guided Therapy Systems, Llc Energy based hyperhidrosis treatment
US8690778B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Energy-based tissue tightening
US8690780B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Noninvasive tissue tightening for cosmetic effects
US7491171B2 (en) 2004-10-06 2009-02-17 Guided Therapy Systems, L.L.C. Method and system for treating acne and sebaceous glands
US9833640B2 (en) 2004-10-06 2017-12-05 Guided Therapy Systems, L.L.C. Method and system for ultrasound treatment of skin
US8920324B2 (en) 2004-10-06 2014-12-30 Guided Therapy Systems, Llc Energy based fat reduction
US9833639B2 (en) 2004-10-06 2017-12-05 Guided Therapy Systems, L.L.C. Energy based fat reduction
US8915853B2 (en) 2004-10-06 2014-12-23 Guided Therapy Systems, Llc Methods for face and neck lifts
US8915854B2 (en) 2004-10-06 2014-12-23 Guided Therapy Systems, Llc Method for fat and cellulite reduction
US8690779B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Noninvasive aesthetic treatment for tightening tissue
US20060089632A1 (en) * 2004-10-06 2006-04-27 Guided Therapy Systems, L.L.C. Method and system for treating acne and sebaceous glands
US9283409B2 (en) 2004-10-06 2016-03-15 Guided Therapy Systems, Llc Energy based fat reduction
US8868958B2 (en) 2005-04-25 2014-10-21 Ardent Sound, Inc Method and system for enhancing computer peripheral safety
US8166332B2 (en) 2005-04-25 2012-04-24 Ardent Sound, Inc. Treatment system for enhancing safety of computer peripheral for use with medical devices by isolating host AC power
US20110201976A1 (en) * 2005-06-01 2011-08-18 Focus Surgery, Inc. Laparoscopic hifu probe
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8574251B2 (en) 2005-09-07 2013-11-05 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9005229B2 (en) 2005-09-07 2015-04-14 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9364246B2 (en) 2005-09-07 2016-06-14 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8753339B2 (en) 2005-09-07 2014-06-17 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US9272124B2 (en) 2005-12-02 2016-03-01 Ulthera, Inc. Systems and devices for selective cell lysis and methods of using same
US20080021353A1 (en) * 2005-12-30 2008-01-24 Manfred Menzi Acoustic pressure wave applicator system with conduction pad
US20070213705A1 (en) * 2006-03-08 2007-09-13 Schmid Peter M Insulated needle and system
US9566454B2 (en) 2006-09-18 2017-02-14 Guided Therapy Systems, Llc Method and sysem for non-ablative acne treatment and prevention
US9241683B2 (en) 2006-10-04 2016-01-26 Ardent Sound Inc. Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid
US9492686B2 (en) * 2006-12-04 2016-11-15 Koninklijke Philips N.V. Devices and methods for treatment of skin conditions
US20080139974A1 (en) * 2006-12-04 2008-06-12 Da Silva Luiz B Devices and Methods for Treatment of Skin Conditions
JP2010524591A (en) * 2007-04-19 2010-07-22 ザ ファウンドリー, インコーポレイテッド Method and apparatus for reducing the production of sweat
US20100049178A1 (en) * 2007-04-19 2010-02-25 Deem Mark E Methods and apparatus for reducing sweat production
US8401668B2 (en) 2007-04-19 2013-03-19 Miramar Labs, Inc. Systems and methods for creating an effect using microwave energy to specified tissue
JP2013176628A (en) * 2007-04-19 2013-09-09 Miramar Labs Inc Method and apparatus for reducing sweat production
US9427285B2 (en) 2007-04-19 2016-08-30 Miramar Labs, Inc. Systems and methods for creating an effect using microwave energy to specified tissue
US9241763B2 (en) 2007-04-19 2016-01-26 Miramar Labs, Inc. Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
US9149331B2 (en) * 2007-04-19 2015-10-06 Miramar Labs, Inc. Methods and apparatus for reducing sweat production
WO2008131302A3 (en) * 2007-04-19 2009-12-30 The Foundry, Inc. Methods and apparatus for reducing sweat production
US8688228B2 (en) 2007-04-19 2014-04-01 Miramar Labs, Inc. Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
EP2532320A2 (en) 2007-04-19 2012-12-12 Miramar Labs, Inc. Apparatus for reducing sweat production
US9216276B2 (en) 2007-05-07 2015-12-22 Guided Therapy Systems, Llc Methods and systems for modulating medicants using acoustic energy
US8764687B2 (en) 2007-05-07 2014-07-01 Guided Therapy Systems, Llc Methods and systems for coupling and focusing acoustic energy using a coupler member
US20090062724A1 (en) * 2007-08-31 2009-03-05 Rixen Chen System and apparatus for sonodynamic therapy
US9039722B2 (en) 2007-10-09 2015-05-26 Ulthera, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US20090093737A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Ultrasound apparatus with treatment lens
US8406894B2 (en) 2007-12-12 2013-03-26 Miramar Labs, Inc. Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
US8825176B2 (en) 2007-12-12 2014-09-02 Miramar Labs, Inc. Apparatus for the noninvasive treatment of tissue using microwave energy
US20110196365A1 (en) * 2008-10-22 2011-08-11 Miramar Labs, Inc. Systems, Apparatus, Methods, and Procedures for the Non-Invasive Treatment of Tissue Using Microwave Energy
US20100222852A1 (en) * 2009-02-24 2010-09-02 Vasily David B Apparatus and Method for Decolonizing Microbes on the Surfaces of the Skin and In Body Cavities
US8920452B2 (en) 2009-08-07 2014-12-30 Ulthera, Inc. Methods of tissue release to reduce the appearance of cellulite
US8906054B2 (en) 2009-08-07 2014-12-09 Ulthera, Inc. Apparatus for reducing the appearance of cellulite
US8979881B2 (en) 2009-08-07 2015-03-17 Ulthera, Inc. Methods and handpiece for use in tissue dissection
US9044259B2 (en) 2009-08-07 2015-06-02 Ulthera, Inc. Methods for dissection of subcutaneous tissue
US9757145B2 (en) 2009-08-07 2017-09-12 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8900261B2 (en) 2009-08-07 2014-12-02 Ulthera, Inc. Tissue treatment system for reducing the appearance of cellulite
US8900262B2 (en) 2009-08-07 2014-12-02 Ulthera, Inc. Device for dissection of subcutaneous tissue
US9510849B2 (en) 2009-08-07 2016-12-06 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US8894678B2 (en) 2009-08-07 2014-11-25 Ulthera, Inc. Cellulite treatment methods
US9078688B2 (en) 2009-08-07 2015-07-14 Ulthera, Inc. Handpiece for use in tissue dissection
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
US9039617B2 (en) 2009-11-24 2015-05-26 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
US9345910B2 (en) 2009-11-24 2016-05-24 Guided Therapy Systems Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
US9149658B2 (en) 2010-08-02 2015-10-06 Guided Therapy Systems, Llc Systems and methods for ultrasound treatment
US20120165668A1 (en) * 2010-08-02 2012-06-28 Guided Therapy Systems, Llc Systems and methods for treating acute and/or chronic injuries in soft tissue
US9504446B2 (en) 2010-08-02 2016-11-29 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
US8857438B2 (en) 2010-11-08 2014-10-14 Ulthera, Inc. Devices and methods for acoustic shielding
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US9452302B2 (en) 2011-07-10 2016-09-27 Guided Therapy Systems, Llc Systems and methods for accelerating healing of implanted material and/or native tissue
US8858471B2 (en) 2011-07-10 2014-10-14 Guided Therapy Systems, Llc Methods and systems for ultrasound treatment
US9011337B2 (en) 2011-07-11 2015-04-21 Guided Therapy Systems, Llc Systems and methods for monitoring and controlling ultrasound power output and stability
US8469951B2 (en) 2011-08-01 2013-06-25 Miramar Labs, Inc. Applicator and tissue interface module for dermatological device
US9314301B2 (en) 2011-08-01 2016-04-19 Miramar Labs, Inc. Applicator and tissue interface module for dermatological device
US8535302B2 (en) 2011-08-01 2013-09-17 Miramar Labs, Inc. Applicator and tissue interface module for dermatological device
US9028477B2 (en) 2011-08-01 2015-05-12 Miramar Labs, Inc. Applicator and tissue interface module for dermatological device
US8852103B2 (en) 2011-10-17 2014-10-07 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9268015B2 (en) 2011-10-17 2016-02-23 Butterfly Network, Inc. Image-guided high intensity focused ultrasound and related apparatus and methods
US9155521B2 (en) 2011-10-17 2015-10-13 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9268014B2 (en) 2011-10-17 2016-02-23 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9198637B2 (en) 2011-10-17 2015-12-01 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9033884B2 (en) 2011-10-17 2015-05-19 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9028412B2 (en) 2011-10-17 2015-05-12 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9022936B2 (en) 2011-10-17 2015-05-05 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9247924B2 (en) 2011-10-17 2016-02-02 Butterfly Networks, Inc. Transmissive imaging and related apparatus and methods
US9149255B2 (en) 2011-10-17 2015-10-06 Butterfly Network, Inc. Image-guided high intensity focused ultrasound and related apparatus and methods
US20130123625A1 (en) * 2011-11-14 2013-05-16 Boston Scientific Scimed, Inc. Integrated ultrasound ablation and imaging device and related methods
US9263663B2 (en) 2012-04-13 2016-02-16 Ardent Sound, Inc. Method of making thick film transducer arrays
DE102012209008A1 (en) * 2012-05-29 2013-12-05 Wellcomet Gmbh Device for generation of e.g. radio frequency current for pressurization of human tissue with frequency current, has motion sensor cooperating with control unit such that intensity of wave is controlled depending on measurement signals
DE102012209008B4 (en) * 2012-05-29 2015-02-05 Wellcomet Gmbh An apparatus for generating treatment waves
US9510802B2 (en) 2012-09-21 2016-12-06 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
US9802063B2 (en) 2012-09-21 2017-10-31 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
US9667889B2 (en) 2013-04-03 2017-05-30 Butterfly Network, Inc. Portable electronic devices with integrated imaging capabilities

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