JP2023078467A5 - - Google Patents
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- JP2023078467A5 JP2023078467A5 JP2023057334A JP2023057334A JP2023078467A5 JP 2023078467 A5 JP2023078467 A5 JP 2023078467A5 JP 2023057334 A JP2023057334 A JP 2023057334A JP 2023057334 A JP2023057334 A JP 2023057334A JP 2023078467 A5 JP2023078467 A5 JP 2023078467A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024195763A JP2025020347A (ja) | 2017-01-26 | 2024-11-08 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762450804P | 2017-01-26 | 2017-01-26 | |
| US62/450,804 | 2017-01-26 | ||
| US201762487135P | 2017-04-19 | 2017-04-19 | |
| US62/487,135 | 2017-04-19 | ||
| JP2019541341A JP7305543B2 (ja) | 2017-01-26 | 2018-01-26 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
| PCT/US2018/015595 WO2018140821A1 (en) | 2017-01-26 | 2018-01-26 | Tissue-specific wnt signal enhancing molecules and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019541341A Division JP7305543B2 (ja) | 2017-01-26 | 2018-01-26 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024195763A Division JP2025020347A (ja) | 2017-01-26 | 2024-11-08 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023078467A JP2023078467A (ja) | 2023-06-06 |
| JP2023078467A5 true JP2023078467A5 (enExample) | 2023-08-25 |
| JP7635291B2 JP7635291B2 (ja) | 2025-02-25 |
Family
ID=62978866
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019541341A Active JP7305543B2 (ja) | 2017-01-26 | 2018-01-26 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
| JP2023057334A Active JP7635291B2 (ja) | 2017-01-26 | 2023-03-31 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
| JP2024195763A Pending JP2025020347A (ja) | 2017-01-26 | 2024-11-08 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019541341A Active JP7305543B2 (ja) | 2017-01-26 | 2018-01-26 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024195763A Pending JP2025020347A (ja) | 2017-01-26 | 2024-11-08 | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11958891B2 (enExample) |
| EP (1) | EP3574019A4 (enExample) |
| JP (3) | JP7305543B2 (enExample) |
| CN (1) | CN110234662A (enExample) |
| AU (1) | AU2018211985B2 (enExample) |
| CA (1) | CA3050133A1 (enExample) |
| WO (1) | WO2018140821A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11993645B2 (en) | 2017-01-11 | 2024-05-28 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions comprising R-Spondin (RSPO) surrogate molecules |
| EP3574019A4 (en) | 2017-01-26 | 2021-03-03 | Surrozen, Inc. | TISSUE-SPECIFIC WNT SIGNAL ENHANCEMENT MOLECULES AND THEIR USES |
| US11773171B2 (en) | 2017-12-19 | 2023-10-03 | Surrozen Operating, Inc. | WNT surrogate molecules and uses thereof |
| CN111699003B (zh) | 2017-12-19 | 2024-05-03 | 瑟罗泽恩奥普瑞汀公司 | 抗lrp5/6抗体和使用方法 |
| EP4603508A3 (en) | 2017-12-19 | 2025-10-29 | Surrozen Operating, Inc. | Anti-frizzled antibodies and methods of use |
| CA3104868A1 (en) | 2018-07-09 | 2020-01-16 | Surrozen, Inc. | Tissue-specific wnt signal enhancing molecules and uses thereof |
| EP3886905A4 (en) * | 2018-12-27 | 2022-08-24 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | BISPECIFIC ANTIBODY FOR MEMBRANE CLEARANCE OF TARGET RECEPTORS |
| WO2020167848A1 (en) * | 2019-02-11 | 2020-08-20 | Surrozen, Inc. | Modulation of wnt signalling in ocular disorders |
| US20220175884A1 (en) * | 2019-04-02 | 2022-06-09 | Surrozen Operating, Inc. | Modulation of wnt signaling in auditory disorders |
| KR20220024460A (ko) * | 2019-06-11 | 2022-03-03 | 안틀라 테라퓨틱스 아이엔씨. | 다가 fzd 및 wnt 결합 분자 및 이의 용도 |
| US11713461B2 (en) | 2019-06-21 | 2023-08-01 | Regeneran Pharmaceuticals, Inc. | Treatment of decreased bone mineral density with zinc and ring finger 3 (ZNRF3) inhibitors |
| KR102192471B1 (ko) * | 2019-10-18 | 2020-12-17 | 주식회사 인코스팜 | 탈모 완화 및 모발 성장을 촉진시키는 펩타이드 및 이를 포함하는 화장료 조성물 |
| US20240000890A1 (en) * | 2020-01-09 | 2024-01-04 | Retinal Solutions, LLC | Neural regeneration with synthetic protein administration |
| CA3170340A1 (en) * | 2020-02-24 | 2021-09-02 | Surrozen Operating, Inc. | Wnt super agonists |
| CA3200523A1 (en) * | 2020-11-10 | 2022-05-19 | The Scripps Research Institute | Antibodies for opioid treatments |
| KR20230109668A (ko) * | 2020-11-16 | 2023-07-20 | 서로젠 오퍼레이팅, 인크. | 간-특이적 Wnt 신호 증강 분자 및 그의 용도 |
| CN112386687B (zh) * | 2020-12-09 | 2021-05-04 | 爱龄医美国际健康咨询服务(北京)有限公司 | 一种干细胞外泌体及其在药品和化妆品中的应用 |
| CN113307882B (zh) * | 2021-05-12 | 2022-12-20 | 东北大学 | 靶向治疗Rspo过度激活导致的结直肠癌的融合蛋白SZ1及其偶联纳米药物 |
| CN113293214A (zh) * | 2021-06-17 | 2021-08-24 | 深圳华因康基因科技有限公司 | 一种检测神经母细胞瘤复发转移基因wnt2扩增的引物探针及其应用 |
| WO2023285686A2 (en) * | 2021-07-15 | 2023-01-19 | Diogenx | Recombinant variants of r-spondin proteins and their use |
| WO2023080159A1 (ja) * | 2021-11-02 | 2023-05-11 | レナセラピューティクス株式会社 | リガンド結合核酸複合体 |
| CN116789843B (zh) * | 2022-03-16 | 2024-09-17 | 伯桢生物科技(杭州)有限公司 | Wnt重组蛋白及其应用 |
| CN116836274B (zh) * | 2022-03-23 | 2024-11-22 | 东莞市朋志生物科技有限公司 | 抗血清淀粉样蛋白a抗体、检测血清淀粉样蛋白a的试剂和试剂盒 |
| CA3258980A1 (en) * | 2022-06-21 | 2023-12-28 | Surrozen Operating, Inc. | WNT SIGNALING MODULATION IN CORNEAL DISORDERS |
| WO2025146152A1 (zh) * | 2024-01-04 | 2025-07-10 | 上海宝济药业股份有限公司 | 一种药物组合物及其应用 |
| CN120647751B (zh) * | 2025-08-18 | 2025-12-02 | 成都迈科康生物科技有限公司 | 抗人乳头瘤病毒e1蛋白的抗体或其试剂盒和相关应用 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030044409A1 (en) | 2001-05-01 | 2003-03-06 | Carson Dennis A. | Immunologic compositions and methods for studying and treating cancers expressing frizzled antigens |
| SI2157192T1 (sl) * | 2003-10-10 | 2013-11-29 | Deutsches Krebsforschungszentrum | Sestavki za diagnozo in terapijo bolezni, povezanih z aberantno ekspresijo Futrinov (R-Spondinov) |
| DE102004050620A1 (de) | 2004-10-13 | 2006-04-20 | Eberhard-Karls-Universität Tübingen | Monoklonaler Antikörper gegen Frizzled-Rezeptoren |
| DE102005035568A1 (de) | 2005-07-25 | 2007-02-01 | M-Phasys Gmbh | Frizzled 9 als Biomarker für Substrukturen des humanen Gehirns |
| EP4174179B1 (en) | 2005-08-23 | 2025-05-07 | The Trustees of the University of Pennsylvania | Rna containing modified nucleosides and methods of use thereof |
| EP2044123B1 (en) | 2006-06-21 | 2013-03-13 | Oncotherapy Science, Inc. | Tumor-targeting monoclonal antibodies to fzd10 and uses thereof |
| EP2050466B1 (en) | 2006-08-14 | 2015-10-28 | Chugai Seiyaku Kabushiki Kaisha | Diagnosis and treatment of cancer using anti-desmoglein-3 antibodies |
| JPWO2008093646A1 (ja) | 2007-02-01 | 2010-05-20 | 国立大学法人 奈良先端科学技術大学院大学 | Ｗｎｔシグナル伝達系活性化ペプチド |
| CN105079805A (zh) | 2008-09-26 | 2015-11-25 | 昂考梅德药品有限公司 | 卷曲蛋白结合药剂及其应用 |
| JO3382B1 (ar) | 2008-12-23 | 2019-03-13 | Amgen Inc | أجسام مضادة ترتبط مع مستقبل cgrp بشري |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| SG173492A1 (en) | 2009-02-03 | 2011-09-29 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising said stem cells. |
| WO2010092457A1 (en) | 2009-02-10 | 2010-08-19 | Nokia Corporation | Method, apparatus and computer program product for transfer of capability support information in a multi-rat environment |
| EP2305274A1 (en) * | 2009-09-21 | 2011-04-06 | Centre National de la Recherche Scientifique (CNRS) | Use of WNT stimulators for treating demyelinating diseases |
| EP2510012B1 (en) | 2009-12-09 | 2017-04-19 | Bayer Pharma Aktiengesellschaft | Anti-c4.4a antibodies and uses thereof |
| NZ602700A (en) | 2010-04-01 | 2014-10-31 | Oncomed Pharm Inc | Frizzled-binding agents and uses thereof |
| CA3122219A1 (en) | 2010-04-16 | 2011-10-20 | The Children's Hospital Corporation | Sustained polypeptide expression from synthetic, modified rnas and uses thereof |
| RS63430B1 (sr) | 2010-10-01 | 2022-08-31 | Modernatx Inc | Ribonukleinske kiseline koje sadrže n1-metil-pseudouracile i njihove primene |
| SI2691417T2 (sl) | 2011-03-29 | 2025-05-30 | Roche Glycart Ag | FC variante protitelesa |
| JP2014511694A (ja) | 2011-04-03 | 2014-05-19 | ザ ジェネラル ホスピタル コーポレーション ドゥーイング ビジネス アズ マサチューセッツ ジェネラル ホスピタル | 修飾型ｒｎａ（ｍｏｄ−ｒｎａ）を使用する効率的なインビボタンパク質発現 |
| GB201106395D0 (en) | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| DK3682905T3 (da) | 2011-10-03 | 2022-02-28 | Modernatx Inc | Modificerede nukleosider, nukleotider og nukleinsyrer og anvendelser deraf |
| EP3653222A1 (en) | 2011-10-14 | 2020-05-20 | Novartis AG | Antibodies and methods for wnt pathway-related diseases |
| WO2013071047A1 (en) | 2011-11-11 | 2013-05-16 | Children's Medical Center Corporation | Compositions and methods for in vitro transcription of rna |
| WO2013078199A2 (en) | 2011-11-23 | 2013-05-30 | Children's Medical Center Corporation | Methods for enhanced in vivo delivery of synthetic, modified rnas |
| RU2017120287A (ru) | 2012-02-28 | 2018-11-15 | АйАрЭм ЭлЭлСи | ОТБОР БОЛЬНЫХ РАКОМ ДЛЯ ВВЕДЕНИЯ ИНГИБИТОРОВ СИГНАЛЬНОГО ПУТИ Wnt НА ОСНОВАНИИ СТАТУСА МУТАЦИИ RNF43 |
| CN104411338A (zh) | 2012-04-02 | 2015-03-11 | 现代治疗公司 | 用于产生与人类疾病相关的生物制剂和蛋白质的修饰多核苷酸 |
| CN104704001B (zh) | 2012-08-09 | 2019-02-12 | 罗切格利卡特公司 | Asgpr抗体及其用途 |
| HRP20220607T1 (hr) | 2012-11-26 | 2022-06-24 | Modernatx, Inc. | Terminalno modificirana rna |
| EP2931319B1 (en) | 2012-12-13 | 2019-08-21 | ModernaTX, Inc. | Modified nucleic acid molecules and uses thereof |
| US20160022840A1 (en) | 2013-03-09 | 2016-01-28 | Moderna Therapeutics, Inc. | Heterologous untranslated regions for mrna |
| EA201692100A8 (ru) | 2014-04-21 | 2018-11-30 | ЭББВИ СТЕМСЕНТРКС ЭлЭлСи | Новые антитела против rnf43 и способы их применения |
| EP3191526B1 (en) | 2014-09-12 | 2023-02-22 | The Board of Trustees of the Leland Stanford Junior University | Wnt signaling agonist molecules |
| US10259874B2 (en) | 2014-10-27 | 2019-04-16 | Agency For Science, Technology And Research | Anti-TIM-3 antibodies |
| WO2016073906A2 (en) | 2014-11-06 | 2016-05-12 | Scholar Rock, Inc. | Transforming growth factor-related immunoassays |
| JP6993228B2 (ja) | 2014-11-19 | 2022-03-03 | ジェネンテック， インコーポレイテッド | 抗トランスフェリン受容体／抗ｂａｃｅ１多重特異性抗体および使用方法 |
| EA201792294A1 (ru) * | 2015-04-17 | 2018-03-30 | Мерримак Фармасьютикалс, Инк. | Комбинированное лечение (варианты) с применением серибантумаба |
| US11939394B2 (en) * | 2015-10-23 | 2024-03-26 | Merus N.V. | Binding molecules that inhibit cancer growth |
| EA201891277A1 (ru) | 2015-12-08 | 2018-11-30 | Ридженерон Фармасьютикалз, Инк. | Композиции и способы интернализации ферментов |
| US20170349659A1 (en) | 2016-06-03 | 2017-12-07 | The Board Of Trustees Of The Leland Stanford Junior University | Wnt signaling agonist molecules |
| WO2018107116A1 (en) | 2016-12-09 | 2018-06-14 | Abbvie Stemcentrx Llc | Methods of reducing toxicity of antibody drug conjugates, and compositions produced thereby |
| US11993645B2 (en) | 2017-01-11 | 2024-05-28 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions comprising R-Spondin (RSPO) surrogate molecules |
| EP3574019A4 (en) | 2017-01-26 | 2021-03-03 | Surrozen, Inc. | TISSUE-SPECIFIC WNT SIGNAL ENHANCEMENT MOLECULES AND THEIR USES |
| US20200123256A1 (en) | 2017-05-02 | 2020-04-23 | Chugai Seiyaku Kabushiki Kaisha | Cytotoxicity-inducing therapeutic agent |
| GB201708330D0 (en) | 2017-05-24 | 2017-07-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Fusion protein for enhancing intestinal regeneration |
| CN111699003B (zh) | 2017-12-19 | 2024-05-03 | 瑟罗泽恩奥普瑞汀公司 | 抗lrp5/6抗体和使用方法 |
| US11773171B2 (en) | 2017-12-19 | 2023-10-03 | Surrozen Operating, Inc. | WNT surrogate molecules and uses thereof |
| EP4603508A3 (en) | 2017-12-19 | 2025-10-29 | Surrozen Operating, Inc. | Anti-frizzled antibodies and methods of use |
| WO2020010308A1 (en) | 2018-07-05 | 2020-01-09 | Surrozen, Inc. | Multi-specific wnt surrogate molecules and uses thereof |
| CA3104868A1 (en) | 2018-07-09 | 2020-01-16 | Surrozen, Inc. | Tissue-specific wnt signal enhancing molecules and uses thereof |
| WO2020132356A1 (en) | 2018-12-19 | 2020-06-25 | Surrozen, Inc. | Antigen binding formats for receptor complexes |
| WO2020167848A1 (en) | 2019-02-11 | 2020-08-20 | Surrozen, Inc. | Modulation of wnt signalling in ocular disorders |
| EP3938036A4 (en) | 2019-03-11 | 2023-06-28 | Surrozen Operating, Inc. | Modulation of wnt signaling in gastrointestinal disorders |
| US20220175884A1 (en) | 2019-04-02 | 2022-06-09 | Surrozen Operating, Inc. | Modulation of wnt signaling in auditory disorders |
| KR20220024460A (ko) | 2019-06-11 | 2022-03-03 | 안틀라 테라퓨틱스 아이엔씨. | 다가 fzd 및 wnt 결합 분자 및 이의 용도 |
| US11050604B2 (en) | 2019-07-01 | 2021-06-29 | Rampart Communications, Inc. | Systems, methods and apparatuses for modulation-agnostic unitary braid division multiplexing signal transformation |
| CA3170340A1 (en) | 2020-02-24 | 2021-09-02 | Surrozen Operating, Inc. | Wnt super agonists |
| KR20230109668A (ko) | 2020-11-16 | 2023-07-20 | 서로젠 오퍼레이팅, 인크. | 간-특이적 Wnt 신호 증강 분자 및 그의 용도 |
| JP2024509266A (ja) | 2021-03-10 | 2024-02-29 | スロゼン オペレーティング， インコーポレイテッド | 胃腸障害におけるｗｎｔシグナル伝達のモジュレーション |
-
2018
- 2018-01-26 EP EP18744610.9A patent/EP3574019A4/en active Pending
- 2018-01-26 JP JP2019541341A patent/JP7305543B2/ja active Active
- 2018-01-26 CN CN201880008831.XA patent/CN110234662A/zh active Pending
- 2018-01-26 WO PCT/US2018/015595 patent/WO2018140821A1/en not_active Ceased
- 2018-01-26 AU AU2018211985A patent/AU2018211985B2/en active Active
- 2018-01-26 CA CA3050133A patent/CA3050133A1/en active Pending
- 2018-01-26 US US16/481,001 patent/US11958891B2/en active Active
-
2023
- 2023-03-31 JP JP2023057334A patent/JP7635291B2/ja active Active
-
2024
- 2024-03-06 US US18/597,679 patent/US20240279303A1/en active Pending
- 2024-11-08 JP JP2024195763A patent/JP2025020347A/ja active Pending
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