AU2018211985B2 - Tissue-specific Wnt signal enhancing molecules and uses thereof - Google Patents
Tissue-specific Wnt signal enhancing molecules and uses thereof Download PDFInfo
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- AU2018211985B2 AU2018211985B2 AU2018211985A AU2018211985A AU2018211985B2 AU 2018211985 B2 AU2018211985 B2 AU 2018211985B2 AU 2018211985 A AU2018211985 A AU 2018211985A AU 2018211985 A AU2018211985 A AU 2018211985A AU 2018211985 B2 AU2018211985 B2 AU 2018211985B2
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- General Chemical & Material Sciences (AREA)
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- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
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- Wood Science & Technology (AREA)
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- Diabetes (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762450804P | 2017-01-26 | 2017-01-26 | |
| US62/450,804 | 2017-01-26 | ||
| US201762487135P | 2017-04-19 | 2017-04-19 | |
| US62/487,135 | 2017-04-19 | ||
| PCT/US2018/015595 WO2018140821A1 (en) | 2017-01-26 | 2018-01-26 | Tissue-specific wnt signal enhancing molecules and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2018211985A1 AU2018211985A1 (en) | 2019-07-18 |
| AU2018211985B2 true AU2018211985B2 (en) | 2025-02-13 |
Family
ID=62978866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018211985A Active AU2018211985B2 (en) | 2017-01-26 | 2018-01-26 | Tissue-specific Wnt signal enhancing molecules and uses thereof |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11958891B2 (enExample) |
| EP (1) | EP3574019A4 (enExample) |
| JP (3) | JP7305543B2 (enExample) |
| CN (1) | CN110234662A (enExample) |
| AU (1) | AU2018211985B2 (enExample) |
| CA (1) | CA3050133A1 (enExample) |
| WO (1) | WO2018140821A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11993645B2 (en) | 2017-01-11 | 2024-05-28 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions comprising R-Spondin (RSPO) surrogate molecules |
| WO2018140821A1 (en) | 2017-01-26 | 2018-08-02 | Surrozen, Inc. | Tissue-specific wnt signal enhancing molecules and uses thereof |
| US11746150B2 (en) | 2017-12-19 | 2023-09-05 | Surrozen Operating, Inc. | Anti-LRP5/6 antibodies and methods of use |
| US11773171B2 (en) | 2017-12-19 | 2023-10-03 | Surrozen Operating, Inc. | WNT surrogate molecules and uses thereof |
| CA3085596A1 (en) | 2017-12-19 | 2019-06-27 | Surrozen, Inc. | Anti-frizzled antibodies and methods of use |
| AU2019301633A1 (en) | 2018-07-09 | 2021-01-28 | Surrozen Operating, Inc. | Tissue-specific Wnt signal enhancing molecules and uses |
| US20220041753A1 (en) * | 2018-12-27 | 2022-02-10 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Bispecific antibody for membrane clearance of target receptors |
| CN113544150A (zh) * | 2019-02-11 | 2021-10-22 | 瑟罗泽恩公司 | 眼部病症中wnt信号传导的调节 |
| WO2020206005A1 (en) * | 2019-04-02 | 2020-10-08 | Surrozen, Inc. | Modulation of wnt signaling in auditory disorders |
| AU2020291208A1 (en) * | 2019-06-11 | 2022-01-06 | Antlera Therapeutics Inc. | Multivalent FZD and Wnt binding molecules and uses thereof |
| EP3986912A1 (en) | 2019-06-21 | 2022-04-27 | Regeneron Pharmaceuticals, Inc. | Treatment of decreased bone mineral density with zinc and ring finger 3 (znrf3) inhibitors |
| KR102192471B1 (ko) * | 2019-10-18 | 2020-12-17 | 주식회사 인코스팜 | 탈모 완화 및 모발 성장을 촉진시키는 펩타이드 및 이를 포함하는 화장료 조성물 |
| WO2021142410A1 (en) * | 2020-01-09 | 2021-07-15 | Retinal Solutions, LLC | Neural regeneration with synthetic protein administration |
| CN115427446A (zh) * | 2020-02-24 | 2022-12-02 | 瑟罗泽恩奥普瑞汀公司 | Wnt超级激动剂 |
| EP4244256A4 (en) * | 2020-11-10 | 2024-12-25 | The Scripps Research Institute | ANTIBODIES FOR OPIOID TREATMENTS |
| JP2023549854A (ja) * | 2020-11-16 | 2023-11-29 | スロゼン オペレーティング, インコーポレイテッド | 肝臓特異的Wntシグナル増強分子およびその使用 |
| CN112386687B (zh) * | 2020-12-09 | 2021-05-04 | 爱龄医美国际健康咨询服务(北京)有限公司 | 一种干细胞外泌体及其在药品和化妆品中的应用 |
| CN113307882B (zh) * | 2021-05-12 | 2022-12-20 | 东北大学 | 靶向治疗Rspo过度激活导致的结直肠癌的融合蛋白SZ1及其偶联纳米药物 |
| CN113293214A (zh) * | 2021-06-17 | 2021-08-24 | 深圳华因康基因科技有限公司 | 一种检测神经母细胞瘤复发转移基因wnt2扩增的引物探针及其应用 |
| WO2023285686A2 (en) * | 2021-07-15 | 2023-01-19 | Diogenx | Recombinant variants of r-spondin proteins and their use |
| EP4428238A1 (en) * | 2021-11-02 | 2024-09-11 | Rena Therapeutics Inc. | Ligand-bound nucleic acid complex |
| CN116789843B (zh) * | 2022-03-16 | 2024-09-17 | 伯桢生物科技(杭州)有限公司 | Wnt重组蛋白及其应用 |
| CN116836274B (zh) * | 2022-03-23 | 2024-11-22 | 东莞市朋志生物科技有限公司 | 抗血清淀粉样蛋白a抗体、检测血清淀粉样蛋白a的试剂和试剂盒 |
| EP4543928A2 (en) * | 2022-06-21 | 2025-04-30 | Surrozen Operating, Inc. | Modulation of wnt signalling in corneal disorders |
| WO2025146152A1 (zh) * | 2024-01-04 | 2025-07-10 | 上海宝济药业股份有限公司 | 一种药物组合物及其应用 |
| CN120647751B (zh) * | 2025-08-18 | 2025-12-02 | 成都迈科康生物科技有限公司 | 抗人乳头瘤病毒e1蛋白的抗体或其试剂盒和相关应用 |
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| US20070244061A1 (en) * | 2003-10-10 | 2007-10-18 | Deutsches Krebsforschungszentrum | Compositions for Diagnosis and Therapy of Diseases Associated with Aberrant Expression of Futrins (R-Spondisn) and/or Wnt |
| EP2305274A1 (en) * | 2009-09-21 | 2011-04-06 | Centre National de la Recherche Scientifique (CNRS) | Use of WNT stimulators for treating demyelinating diseases |
| WO2013054307A2 (en) * | 2011-10-14 | 2013-04-18 | Novartis Ag | Antibodies and methods for wnt pathway-related diseases |
| US20140044713A1 (en) * | 2011-04-14 | 2014-02-13 | Koninklijke Nederlandse Akademie Van Wetenschappen | Compounds |
| WO2017069628A2 (en) * | 2015-10-23 | 2017-04-27 | Merus N.V. | Binding molecules that inhibit cancer growth |
| WO2018132572A1 (en) * | 2017-01-11 | 2018-07-19 | The Board Of Trustees Of The Leland Stanford Junior University | R-spondin (rspo) surrogate molecules |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US11958891B2 (en) | 2024-04-16 |
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