CA3050133A1 - Tissue-specific wnt signal enhancing molecules and uses thereof - Google Patents

Tissue-specific wnt signal enhancing molecules and uses thereof Download PDF

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Publication number
CA3050133A1
CA3050133A1 CA3050133A CA3050133A CA3050133A1 CA 3050133 A1 CA3050133 A1 CA 3050133A1 CA 3050133 A CA3050133 A CA 3050133A CA 3050133 A CA3050133 A CA 3050133A CA 3050133 A1 CA3050133 A1 CA 3050133A1
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Prior art keywords
tissue
polypeptide
wnt
molecule
domain
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CA3050133A
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English (en)
French (fr)
Inventor
Zhengjian ZHANG
Jennifer Jean BRADY
Aaron Ken Sato
Wen-Chen Yeh
Yang Li
Teppei YAMAGUCHI
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Surrozen Operating Inc
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Surrozen Inc
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Publication of CA3050133A1 publication Critical patent/CA3050133A1/en
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CA3050133A 2017-01-26 2018-01-26 Tissue-specific wnt signal enhancing molecules and uses thereof Pending CA3050133A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762450804P 2017-01-26 2017-01-26
US62/450,804 2017-01-26
US201762487135P 2017-04-19 2017-04-19
US62/487,135 2017-04-19
PCT/US2018/015595 WO2018140821A1 (en) 2017-01-26 2018-01-26 Tissue-specific wnt signal enhancing molecules and uses thereof

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Publication Number Publication Date
CA3050133A1 true CA3050133A1 (en) 2018-08-02

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Application Number Title Priority Date Filing Date
CA3050133A Pending CA3050133A1 (en) 2017-01-26 2018-01-26 Tissue-specific wnt signal enhancing molecules and uses thereof

Country Status (7)

Country Link
US (2) US11958891B2 (enExample)
EP (1) EP3574019A4 (enExample)
JP (3) JP7305543B2 (enExample)
CN (1) CN110234662A (enExample)
AU (1) AU2018211985B2 (enExample)
CA (1) CA3050133A1 (enExample)
WO (1) WO2018140821A1 (enExample)

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JP7317016B2 (ja) 2017-12-19 2023-07-28 スロゼン オペレーティング， インコーポレイテッド 抗ｌｒｐ５／６抗体及び使用方法
JP7418332B2 (ja) 2017-12-19 2024-01-19 スロゼン オペレーティング， インコーポレイテッド 抗フリズルド抗体及び使用方法
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EP3820499A4 (en) 2018-07-09 2022-07-13 Surrozen Operating, Inc. TISSUE SPECIFIC WNT SIGNAL ENHANCEMENT MOLECULES AND USES
WO2020139950A1 (en) * 2018-12-27 2020-07-02 H. Lee Moffitt Cancer Center And Research Institute Inc. Bispecific antibody for membrane clearance of target receptors
WO2020167848A1 (en) * 2019-02-11 2020-08-20 Surrozen, Inc. Modulation of wnt signalling in ocular disorders
US20220175884A1 (en) * 2019-04-02 2022-06-09 Surrozen Operating, Inc. Modulation of wnt signaling in auditory disorders
CA3140580A1 (en) * 2019-06-11 2020-12-17 Antlera Therapeutics Inc. Multivalent fzd and wnt binding molecules and uses thereof
CA3141632A1 (en) 2019-06-21 2020-12-24 Regeneron Pharmaceuticals, Inc. Treatment of decreased bone mineral density with zinc and ring finger 3 (znrf3) inhibitors
KR102192471B1 (ko) * 2019-10-18 2020-12-17 주식회사 인코스팜 탈모 완화 및 모발 성장을 촉진시키는 펩타이드 및 이를 포함하는 화장료 조성물
EP4087597A4 (en) * 2020-01-09 2023-07-05 Retinal Solutions, LLC NEURONAL REGENERATION WITH SYNTHETIC PROTEIN DELIVERY
EP4110821A4 (en) * 2020-02-24 2024-04-10 Surrozen Operating, Inc. WNT SUPERAGONISTS
EP4244256A4 (en) * 2020-11-10 2024-12-25 The Scripps Research Institute ANTIBODIES FOR OPIOID TREATMENTS
CA3198268A1 (en) * 2020-11-16 2022-05-19 Surrozen Operating, Inc. Liver-specific wnt signal enhancing molecules and uses thereof
CN112386687B (zh) * 2020-12-09 2021-05-04 爱龄医美国际健康咨询服务(北京)有限公司 一种干细胞外泌体及其在药品和化妆品中的应用
CN113307882B (zh) * 2021-05-12 2022-12-20 东北大学 靶向治疗Rspo过度激活导致的结直肠癌的融合蛋白SZ1及其偶联纳米药物
CN113293214A (zh) * 2021-06-17 2021-08-24 深圳华因康基因科技有限公司 一种检测神经母细胞瘤复发转移基因wnt2扩增的引物探针及其应用
IL310154A (en) * 2021-07-15 2024-03-01 Diogenx Recombinant variants of r-spondin proteins and their use
WO2023080159A1 (ja) * 2021-11-02 2023-05-11 レナセラピューティクス株式会社 リガンド結合核酸複合体
CN116789843B (zh) * 2022-03-16 2024-09-17 伯桢生物科技(杭州)有限公司 Wnt重组蛋白及其应用
CN116836274B (zh) * 2022-03-23 2024-11-22 东莞市朋志生物科技有限公司 抗血清淀粉样蛋白a抗体、检测血清淀粉样蛋白a的试剂和试剂盒
JP2025525362A (ja) * 2022-06-21 2025-08-05 スロゼン オペレーティング， インコーポレイテッド 角膜障害におけるｗｎｔシグナル伝達の調節
CN119744268A (zh) * 2022-09-09 2025-04-01 德国癌症研究中心公共法律基金会 靶向pd-l1降解
WO2025146152A1 (zh) * 2024-01-04 2025-07-10 上海宝济药业股份有限公司 一种药物组合物及其应用
CN120647751B (zh) * 2025-08-18 2025-12-02 成都迈科康生物科技有限公司 抗人乳头瘤病毒e1蛋白的抗体或其试剂盒和相关应用

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