JP2022027762A5 - - Google Patents
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- JP2022027762A5 JP2022027762A5 JP2021183110A JP2021183110A JP2022027762A5 JP 2022027762 A5 JP2022027762 A5 JP 2022027762A5 JP 2021183110 A JP2021183110 A JP 2021183110A JP 2021183110 A JP2021183110 A JP 2021183110A JP 2022027762 A5 JP2022027762 A5 JP 2022027762A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- hinge
- composition
- car
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024010098A JP2024028648A (ja) | 2015-11-27 | 2024-01-26 | 遺伝子改変された細胞およびその使用 |
| JP2025265629A JP2026034683A (ja) | 2015-11-27 | 2025-12-18 | 遺伝子改変された細胞およびその使用 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015904933 | 2015-11-27 | ||
| AU2015904933A AU2015904933A0 (en) | 2015-11-27 | Genetically modified cells and uses thereof | |
| AU2016901328A AU2016901328A0 (en) | 2016-04-11 | Genetically modified cells and uses thereof - III | |
| AU2016901328 | 2016-04-11 | ||
| JP2018546725A JP6976960B2 (ja) | 2015-11-27 | 2016-11-23 | 遺伝子改変された細胞およびその使用 |
| PCT/AU2016/051141 WO2017088012A1 (en) | 2015-11-27 | 2016-11-23 | Genetically modified cells and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018546725A Division JP6976960B2 (ja) | 2015-11-27 | 2016-11-23 | 遺伝子改変された細胞およびその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024010098A Division JP2024028648A (ja) | 2015-11-27 | 2024-01-26 | 遺伝子改変された細胞およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022027762A JP2022027762A (ja) | 2022-02-14 |
| JP2022027762A5 true JP2022027762A5 (https=) | 2022-06-23 |
Family
ID=58762790
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018546725A Active JP6976960B2 (ja) | 2015-11-27 | 2016-11-23 | 遺伝子改変された細胞およびその使用 |
| JP2021183110A Pending JP2022027762A (ja) | 2015-11-27 | 2021-11-10 | 遺伝子改変された細胞およびその使用 |
| JP2024010098A Pending JP2024028648A (ja) | 2015-11-27 | 2024-01-26 | 遺伝子改変された細胞およびその使用 |
| JP2025265629A Pending JP2026034683A (ja) | 2015-11-27 | 2025-12-18 | 遺伝子改変された細胞およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018546725A Active JP6976960B2 (ja) | 2015-11-27 | 2016-11-23 | 遺伝子改変された細胞およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024010098A Pending JP2024028648A (ja) | 2015-11-27 | 2024-01-26 | 遺伝子改変された細胞およびその使用 |
| JP2025265629A Pending JP2026034683A (ja) | 2015-11-27 | 2025-12-18 | 遺伝子改変された細胞およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11400145B2 (https=) |
| EP (3) | EP3380117B1 (https=) |
| JP (4) | JP6976960B2 (https=) |
| CN (2) | CN109152824B (https=) |
| AU (2) | AU2016361451B2 (https=) |
| CA (1) | CA3004120A1 (https=) |
| ES (2) | ES2862907T3 (https=) |
| IL (2) | IL296410A (https=) |
| MY (1) | MY189819A (https=) |
| SG (2) | SG11201803493UA (https=) |
| WO (1) | WO2017088012A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4406604A3 (en) | 2015-03-05 | 2024-10-23 | Fred Hutchinson Cancer Center | Immunomodulatory fusion proteins and uses thereof |
| AU2016361451B2 (en) * | 2015-11-27 | 2024-01-25 | Cartherics Pty. Ltd. | Genetically modified cells and uses thereof |
| CN109562126A (zh) * | 2016-06-24 | 2019-04-02 | 美商生物细胞基因治疗有限公司 | 嵌合抗原受体(car)、组合物及其使用方法 |
| KR102546839B1 (ko) | 2016-08-03 | 2023-06-23 | 워싱턴 유니버시티 | 키메라 항원 수용체를 이용한 t 세포 악성종양의 치료를 위한 car-t 세포의 유전자 편집 |
| US11525119B2 (en) | 2016-09-06 | 2022-12-13 | The Children's Medical Center Corporation | Immune cells derived from induced pluripotent stem cell |
| CN119409836A (zh) | 2017-03-17 | 2025-02-11 | 弗雷德哈钦森癌症中心 | 免疫调节融合蛋白及其用途 |
| CA3058807A1 (en) | 2017-04-03 | 2018-10-11 | Biontech Us Inc. | Protein antigens and uses thereof |
| SG11201909331UA (en) * | 2017-04-18 | 2019-11-28 | Fujifilm Cellular Dynamics Inc | Antigen-specific immune effector cells |
| US11771718B2 (en) * | 2017-10-18 | 2023-10-03 | Precigen, Inc. | Polypeptide compositions comprising spacers |
| TW201930340A (zh) | 2017-12-18 | 2019-08-01 | 美商尼恩醫療公司 | 新抗原及其用途 |
| CN109971721B (zh) * | 2017-12-28 | 2023-10-31 | 上海细胞治疗研究院 | 自表达cd47抗体的间皮素特异性car-t细胞及其用途 |
| CN109971716B (zh) * | 2017-12-28 | 2023-08-01 | 上海细胞治疗研究院 | 自分泌cd47抗体的egfr特异性car-t细胞及其用途 |
| WO2019157454A1 (en) | 2018-02-11 | 2019-08-15 | Memorial Sloan-Kettering Cancer Center | Non-hla restricted t cell receptors and uses thereof |
| JP2021514360A (ja) * | 2018-02-23 | 2021-06-10 | カーサリクス プロプライエタリー リミテッド | Tag−72を標的化するt細胞疾患処置 |
| GB201804701D0 (en) * | 2018-03-23 | 2018-05-09 | Gammadelta Therapeutics Ltd | Lymphocytes expressing heterologous targeting constructs |
| GB201807945D0 (en) * | 2018-05-16 | 2018-06-27 | Ospedale San Raffaele Srl | Vector production |
| EP3801568A4 (en) * | 2018-05-31 | 2022-03-16 | Washington University | GENOMIC-EDITED INVARIANT NATURAL KILLER T CELLS FOR THE TREATMENT OF HEMATOLOGICAL MALIGNITIES |
| MX2020014243A (es) | 2018-06-19 | 2021-05-12 | Biontech Us Inc | Neoantigenos y usos de los mismos. |
| EP3830133A1 (en) | 2018-08-01 | 2021-06-09 | City of Hope | Tag72 targeted chimeric antigen receptor modified t cells for treatment of tag72-positive tumors |
| CA3142947A1 (en) * | 2019-06-12 | 2020-12-17 | The Regents Of The University Of California | Engineered off-the-shelf immune cells and methods of use thereof |
| CA3162755A1 (en) | 2019-11-25 | 2021-06-03 | Kyoto University | T-cell master cell bank |
| US20230203125A1 (en) * | 2020-05-22 | 2023-06-29 | Chongqing Precision Biotech Co., Ltd. | Fusion protein for reversing tumor microenvironment and use thereof |
| EP4161536A4 (en) * | 2020-06-04 | 2024-08-14 | Carisma Therapeutics Inc. | Novel constructs for chimeric antigen receptors |
| WO2022061837A1 (en) * | 2020-09-27 | 2022-03-31 | Jiangsu Cell Tech Medical Research Institute Co., Ltd. | Fibronectin extra domain b (edb) -specific car-t for cancer |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| US12144827B2 (en) | 2021-02-25 | 2024-11-19 | Lyell Immunopharma, Inc. | ROR1 targeting chimeric antigen receptor |
| BR112023018844A2 (pt) * | 2021-04-07 | 2023-10-10 | Century Therapeutics Inc | Composições e métodos para geração de células t gama-delta de células-tronco pluripotentes induzidas |
| WO2022216624A1 (en) * | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells |
| WO2023110824A1 (en) * | 2021-12-15 | 2023-06-22 | Novo Nordisk A/S | Novel integrin associated protein (iap) |
| CN114573710A (zh) * | 2022-02-16 | 2022-06-03 | 南方医科大学珠江医院 | 一种靶向抗原同时外泌cd47抗体的免疫细胞及其应用 |
| WO2024036214A2 (en) * | 2022-08-10 | 2024-02-15 | Jasper Therapeutics, Inc. | Modified stem cell compositions and methods for use |
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| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5350674A (en) | 1992-09-04 | 1994-09-27 | Becton, Dickinson And Company | Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof |
| US5786146A (en) | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| EP0937095A4 (en) * | 1996-10-25 | 1999-12-22 | Cell Genesys Inc | TARGETED CYTOLYSIS OF CANCER CELLS |
| US6908763B1 (en) | 1997-08-22 | 2005-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian common lymphoid progenitor cell |
| US6331393B1 (en) | 1999-05-14 | 2001-12-18 | University Of Southern California | Process for high-throughput DNA methylation analysis |
| US6761883B2 (en) | 1999-06-29 | 2004-07-13 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian myeloid progenitor cell subsets |
| CA2375974C (en) | 1999-06-29 | 2010-11-02 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian myeloid progenitor cell subsets |
| HK1047109A1 (zh) | 1999-10-15 | 2003-02-07 | University Of Massachusetts | 作为指定基因干预工具的rna干预轨迹基因 |
| US6326193B1 (en) | 1999-11-05 | 2001-12-04 | Cambria Biosciences, Llc | Insect control agent |
| AU2001275474A1 (en) | 2000-06-12 | 2001-12-24 | Akkadix Corporation | Materials and methods for the control of nematodes |
| DE10130800B4 (de) | 2001-06-22 | 2005-06-23 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierung mit hoher Sensitivität |
| US7446190B2 (en) * | 2002-05-28 | 2008-11-04 | Sloan-Kettering Institute For Cancer Research | Nucleic acids encoding chimeric T cell receptors |
| AU2003273542A1 (en) | 2002-05-31 | 2003-12-19 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of identifying and isolating stem cells and cancer stem cells |
| US7592174B2 (en) | 2002-05-31 | 2009-09-22 | The Board Of Trustees Of The Leland Stanford Junior University | Isolation of mesenchymal stem cells |
| EP1536688B1 (en) | 2002-09-13 | 2011-12-28 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian megakaryocyte progenitor cell |
| US20050129671A1 (en) | 2003-03-11 | 2005-06-16 | City Of Hope | Mammalian antigen-presenting T cells and bi-specific T cells |
| WO2005021594A2 (en) * | 2003-08-29 | 2005-03-10 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Minimally immunogenic variants of sdr-grafted humanized antibody cc49 and their use |
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| WO2005123909A2 (en) | 2004-06-09 | 2005-12-29 | The Board Of Trustees Of The Leland Stanford Junior University | Isolation and characterization of muscle regenerating cells |
| US7641897B2 (en) | 2004-11-23 | 2010-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Feeder layer and serum independent embryonic stem cells |
| US8691780B2 (en) | 2005-02-17 | 2014-04-08 | The Board Of Trustees Of The Leland Stanford Junior University | Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby |
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| US7514229B2 (en) | 2005-09-29 | 2009-04-07 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for diagnosing and evaluating treatment of blood disorders |
| US8377448B2 (en) | 2006-05-15 | 2013-02-19 | The Board Of Trustees Of The Leland Standford Junior University | CD47 related compositions and methods for treating immunological diseases and disorders |
| EP3424950A1 (en) | 2006-10-06 | 2019-01-09 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Prevention of tissue ischemia, related methods and compositions |
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| US8765390B2 (en) | 2006-12-08 | 2014-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Identification and isolation of squamous carcinoma stem cells |
| EP3043181B1 (en) | 2008-01-15 | 2020-04-08 | The Board of Trustees of the Leland Stanford Junior University | Markers of acute myeloid leukemia stem cells |
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| HRP20230297T1 (hr) | 2012-07-13 | 2023-05-12 | The Trustees Of The University Of Pennsylvania | UPRAVLJANJE TOKSIČNOŠĆU ZA ANTI-TUMORSKO DJELOVANJE CAR-a |
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| WO2014165707A2 (en) * | 2013-04-03 | 2014-10-09 | Memorial Sloan-Kettering Cancer Center | Effective generation of tumor-targeted t-cells derived from pluripotent stem cells |
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| ES2792849T3 (es) * | 2014-02-10 | 2020-11-12 | Univ Emory | Expresión de polipéptido químico con receptores de linfocitos variables en células inmunes y usos para tratar el cáncer |
| US20180214527A1 (en) * | 2015-03-26 | 2018-08-02 | City Of Hope | Bi-specific targeted chimeric antigen receptor t cells |
| KR20250141836A (ko) * | 2015-11-04 | 2025-09-29 | 페이트 세러퓨틱스, 인코포레이티드 | 만능 세포의 유전자 조작 |
| CN105331586B (zh) | 2015-11-20 | 2020-09-15 | 上海细胞治疗研究院 | 一种包含高效杀伤启动机制的肿瘤精准t细胞及其用途 |
| AU2016361451B2 (en) * | 2015-11-27 | 2024-01-25 | Cartherics Pty. Ltd. | Genetically modified cells and uses thereof |
-
2016
- 2016-11-23 AU AU2016361451A patent/AU2016361451B2/en active Active
- 2016-11-23 CA CA3004120A patent/CA3004120A1/en active Pending
- 2016-11-23 SG SG11201803493UA patent/SG11201803493UA/en unknown
- 2016-11-23 CN CN201680069543.6A patent/CN109152824B/zh active Active
- 2016-11-23 US US15/778,836 patent/US11400145B2/en active Active
- 2016-11-23 EP EP16867445.5A patent/EP3380117B1/en active Active
- 2016-11-23 ES ES16867445T patent/ES2862907T3/es active Active
- 2016-11-23 IL IL296410A patent/IL296410A/en unknown
- 2016-11-23 EP EP20169648.1A patent/EP3708588A1/en active Pending
- 2016-11-23 ES ES20169645T patent/ES2988976T3/es active Active
- 2016-11-23 WO PCT/AU2016/051141 patent/WO2017088012A1/en not_active Ceased
- 2016-11-23 EP EP20169645.7A patent/EP3708587B1/en active Active
- 2016-11-23 JP JP2018546725A patent/JP6976960B2/ja active Active
- 2016-11-23 CN CN202211541314.3A patent/CN116121281B/zh active Active
- 2016-11-23 MY MYPI2018701648A patent/MY189819A/en unknown
- 2016-11-23 SG SG10201912825XA patent/SG10201912825XA/en unknown
-
2018
- 2018-05-24 IL IL259586A patent/IL259586B2/en unknown
-
2021
- 2021-11-10 JP JP2021183110A patent/JP2022027762A/ja active Pending
-
2022
- 2022-06-09 US US17/836,052 patent/US20220305106A1/en not_active Abandoned
-
2024
- 2024-01-08 AU AU2024200108A patent/AU2024200108A1/en active Pending
- 2024-01-26 JP JP2024010098A patent/JP2024028648A/ja active Pending
-
2025
- 2025-07-17 US US19/271,861 patent/US20250340612A1/en active Pending
- 2025-12-18 JP JP2025265629A patent/JP2026034683A/ja active Pending
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