JP2022534680A5 - - Google Patents

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Publication number
JP2022534680A5
JP2022534680A5 JP2021568274A JP2021568274A JP2022534680A5 JP 2022534680 A5 JP2022534680 A5 JP 2022534680A5 JP 2021568274 A JP2021568274 A JP 2021568274A JP 2021568274 A JP2021568274 A JP 2021568274A JP 2022534680 A5 JP2022534680 A5 JP 2022534680A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
domain
immune cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2021568274A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022534680A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2020/090600 external-priority patent/WO2020228824A1/en
Publication of JP2022534680A publication Critical patent/JP2022534680A/ja
Publication of JP2022534680A5 publication Critical patent/JP2022534680A5/ja
Ceased legal-status Critical Current

Links

JP2021568274A 2019-05-16 2020-05-15 Cd4結合部分を含む免疫細胞受容体 Ceased JP2022534680A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2019/087260 2019-05-16
CN2019087260 2019-05-16
PCT/CN2020/090600 WO2020228824A1 (en) 2019-05-16 2020-05-15 Immune cell receptors comprsing cd4 binding moieties

Publications (2)

Publication Number Publication Date
JP2022534680A JP2022534680A (ja) 2022-08-03
JP2022534680A5 true JP2022534680A5 (https=) 2023-05-22

Family

ID=73289800

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021568290A Withdrawn JP2022533621A (ja) 2019-05-16 2020-05-15 認識分子を含む操作された免疫細胞
JP2021568274A Ceased JP2022534680A (ja) 2019-05-16 2020-05-15 Cd4結合部分を含む免疫細胞受容体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021568290A Withdrawn JP2022533621A (ja) 2019-05-16 2020-05-15 認識分子を含む操作された免疫細胞

Country Status (8)

Country Link
US (2) US20220265711A1 (https=)
EP (2) EP3969572A4 (https=)
JP (2) JP2022533621A (https=)
KR (2) KR20220010722A (https=)
CN (3) CN118420762A (https=)
AU (2) AU2020275049A1 (https=)
SG (2) SG11202112554UA (https=)
WO (2) WO2020228824A1 (https=)

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Publication number Priority date Publication date Assignee Title
TW202110873A (zh) 2019-04-30 2021-03-16 美商聖堤生物科技股份有限公司 嵌合受體及其使用方法
EP4291573A4 (en) * 2021-02-09 2025-01-29 Nanjing Legend Biotech Co., Ltd. Engineered cells and uses thereof
GB202105684D0 (en) * 2021-04-21 2021-06-02 Imperial College Innovations Ltd Chimeric antigen receptor (CAR)-T cells
EP4381081A1 (en) 2021-08-04 2024-06-12 Sana Biotechnology, Inc. Use of cd4-targeted viral vectors
WO2023114949A1 (en) 2021-12-16 2023-06-22 Sana Biotechnology, Inc. Methods and systems of particle production
EP4463135A2 (en) 2022-01-10 2024-11-20 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
WO2023150647A1 (en) 2022-02-02 2023-08-10 Sana Biotechnology, Inc. Methods of repeat dosing and administration of lipid particles or viral vectors and related systems and uses
WO2023193015A1 (en) 2022-04-01 2023-10-05 Sana Biotechnology, Inc. Cytokine receptor agonist and viral vector combination therapies
WO2024026377A1 (en) 2022-07-27 2024-02-01 Sana Biotechnology, Inc. Methods of transduction using a viral vector and inhibitors of antiviral restriction factors
US20260055146A1 (en) 2022-08-24 2026-02-26 Sana Biotechnology, Inc. Delivery of heterologous proteins
CN116063501A (zh) * 2022-08-29 2023-05-05 华道(上海)生物医药有限公司 一种抗cd4抗体及其用途
WO2024064838A1 (en) 2022-09-21 2024-03-28 Sana Biotechnology, Inc. Lipid particles comprising variant paramyxovirus attachment glycoproteins and uses thereof
CN115819622A (zh) * 2022-09-26 2023-03-21 湖南省人民医院(湖南师范大学附属第一医院) 针对b系白血病或淋巴瘤的双靶点car结构及药物组合物
WO2024119157A1 (en) 2022-12-02 2024-06-06 Sana Biotechnology, Inc. Lipid particles with cofusogens and methods of producing and using the same
WO2024220597A2 (en) 2023-04-18 2024-10-24 Sana Biotechnology, Inc. Digital droplet based assay for detecting replication competent lentiviral vector
CN116836284A (zh) * 2023-04-21 2023-10-03 浙江正熙生物技术有限公司 一种抗人cd4抗体及其制备方法和应用
EP4716750A1 (en) 2023-05-23 2026-04-01 Sana Biotechnology, Inc. Tandem fusogens and related lipid particles
CN121941762A (zh) * 2023-09-25 2026-04-28 詹森生物科技公司 用于产生工程化细胞和/或可工程化细胞的组合物和方法
WO2025184529A1 (en) 2024-03-01 2025-09-04 Sana Biotechnology, Inc. Viral particles with fusogen display and related compositions and methods
WO2026032970A1 (en) 2024-08-07 2026-02-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Cd4-specific chimeric antigen receptor and methods and uses thereof

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
AU2006281803B9 (en) * 2005-08-18 2013-05-30 Genmab A/S Therapy with CD4 binding peptides and radiation
CA2861491C (en) * 2012-02-13 2020-08-25 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
RU2658485C2 (ru) * 2012-10-24 2018-06-21 Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез Химерные антигенные рецепторы м971
JP6839074B2 (ja) * 2014-09-17 2021-03-03 ノバルティス アーゲー 養子免疫療法のためのキメラ受容体での細胞毒性細胞のターゲティング
PL3560953T3 (pl) * 2014-12-24 2024-05-13 Autolus Limited Komórka
JP7237449B2 (ja) * 2015-02-27 2023-03-13 アイセル・ジーン・セラピューティクス・エルエルシー 血液系腫瘍を標的としたキメラ抗体受容体(CARs)の構成およびその使用方法
JP6961490B2 (ja) * 2015-04-08 2021-11-05 ノバルティス アーゲー Cd20療法、cd22療法、およびcd19キメラ抗原受容体(car)発現細胞との併用療法
AU2016274989A1 (en) * 2015-06-12 2017-11-02 Immunomedics, Inc. Disease therapy with chimeric antigen receptor (car) constructs and t cells (car-t) or nk cells (car-nk) expressing car constructs
GB201601077D0 (en) * 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibody molecule
WO2017177175A1 (en) * 2016-04-07 2017-10-12 The George Washington University Methods and compositions targeting retroviral latency
KR20190071677A (ko) * 2016-08-13 2019-06-24 유나이티드 바이오파마, 인크. Haart 안정화된 환자에서 cd4에 대한 항체에 의한 hiv 감염의 치료 및 지속적 바이러스 완화
ES2981703T3 (es) * 2016-09-02 2024-10-10 Lentigen Tech Inc Composiciones y métodos para tratar cáncer con DuoCars
CN107964549B (zh) * 2016-10-20 2020-12-08 上海恒润达生生物科技有限公司 靶向cd22的嵌合抗原受体及其用途
WO2019020733A1 (en) * 2017-07-26 2019-01-31 Cellectis METHODS OF IMMUNE CELL SELECTION OF THE ANTIGEN-DEPENDENT CHIMERIC ANTIGENIC RECEPTOR (CAR)
AU2019302603A1 (en) * 2018-07-13 2021-01-14 Nanjing Legend Biotech Co., Ltd. Co-receptor systems for treating infectious diseases

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