JP2018532407A5 - - Google Patents
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- Publication number
- JP2018532407A5 JP2018532407A5 JP2018520157A JP2018520157A JP2018532407A5 JP 2018532407 A5 JP2018532407 A5 JP 2018532407A5 JP 2018520157 A JP2018520157 A JP 2018520157A JP 2018520157 A JP2018520157 A JP 2018520157A JP 2018532407 A5 JP2018532407 A5 JP 2018532407A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- chimeric receptor
- endodomain
- receptor
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022007006A JP2022058681A (ja) | 2015-10-23 | 2022-01-20 | 受容体 |
| JP2023222448A JP2024024014A (ja) | 2015-10-23 | 2023-12-28 | 受容体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1518816.2 | 2015-10-23 | ||
| GBGB1518816.2A GB201518816D0 (en) | 2015-10-23 | 2015-10-23 | Receptor |
| PCT/GB2016/053290 WO2017068360A1 (en) | 2015-10-23 | 2016-10-21 | Receptor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022007006A Division JP2022058681A (ja) | 2015-10-23 | 2022-01-20 | 受容体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018532407A JP2018532407A (ja) | 2018-11-08 |
| JP2018532407A5 true JP2018532407A5 (https=) | 2019-10-03 |
| JP7082046B2 JP7082046B2 (ja) | 2022-06-07 |
Family
ID=55130152
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520157A Active JP7082046B2 (ja) | 2015-10-23 | 2016-10-21 | 受容体 |
| JP2022007006A Withdrawn JP2022058681A (ja) | 2015-10-23 | 2022-01-20 | 受容体 |
| JP2023222448A Pending JP2024024014A (ja) | 2015-10-23 | 2023-12-28 | 受容体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022007006A Withdrawn JP2022058681A (ja) | 2015-10-23 | 2022-01-20 | 受容体 |
| JP2023222448A Pending JP2024024014A (ja) | 2015-10-23 | 2023-12-28 | 受容体 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11242377B2 (https=) |
| EP (1) | EP3364998A1 (https=) |
| JP (3) | JP7082046B2 (https=) |
| CN (1) | CN108135988A (https=) |
| AU (1) | AU2016342560B2 (https=) |
| CA (1) | CA3001792A1 (https=) |
| GB (1) | GB201518816D0 (https=) |
| HK (1) | HK1252163A1 (https=) |
| WO (1) | WO2017068360A1 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| PL3560953T3 (pl) * | 2014-12-24 | 2024-05-13 | Autolus Limited | Komórka |
| GB201514875D0 (en) | 2015-08-20 | 2015-10-07 | Autolus Ltd | Receptor |
| GB201518816D0 (en) * | 2015-10-23 | 2015-12-09 | Autolus Ltd | Receptor |
| EP3439675A4 (en) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| CN110191955B (zh) * | 2016-12-13 | 2024-05-31 | 西雅图儿童医院（Dba西雅图儿童研究所） | 在体外和体内对工程化的细胞中表达的化学物质诱导的信号传导复合物进行外源性药物激活的方法 |
| US11649288B2 (en) | 2017-02-07 | 2023-05-16 | Seattle Children's Hospital | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| US12312416B2 (en) | 2018-02-06 | 2025-05-27 | Seattle Children's Hospital | Fluorescein-specific cars exhibiting optimal t cell function against FL-PLE labelled tumors |
| AU2019225174B2 (en) | 2018-02-23 | 2025-11-20 | Endocyte, Inc. | Sequencing method for CAR T cell therapy |
| CN111819192A (zh) | 2018-03-02 | 2020-10-23 | 艾洛基治疗公司 | 可诱导的嵌合细胞激素受体 |
| WO2019210057A1 (en) | 2018-04-27 | 2019-10-31 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Rapamycin resistant cells |
| CN110615843B (zh) * | 2018-06-20 | 2023-05-09 | 上海隆耀生物科技有限公司 | 一种包含第三信号受体的嵌合抗原受体及其应用 |
| GB201814203D0 (en) * | 2018-08-31 | 2018-10-17 | King S College London | Engineered regulatory t cell |
| CN111378046B (zh) * | 2018-12-27 | 2024-03-15 | 上海细胞治疗集团有限公司 | 一种免疫效应细胞转换受体 |
| CN114502188B (zh) * | 2019-02-21 | 2025-04-04 | 艾贝乐医药科技有限公司 | 人工免疫监视嵌合抗原受体及其表达细胞 |
| PE20211902A1 (es) | 2019-03-01 | 2021-09-27 | Allogene Therapeutics Inc | Receptores de citocinas quimericos constitutivamente activos |
| AU2020232216B2 (en) | 2019-03-01 | 2025-09-25 | Allogene Therapeutics, Inc. | Chimeric cytokine receptors bearing a PD-1 ectodomain |
| US12528856B2 (en) | 2019-08-30 | 2026-01-20 | Allogene Therapeutics, Inc. | Chimeric cytokine receptors comprising TGF β binding domains |
| EP4031583A4 (en) * | 2019-09-16 | 2023-11-15 | Fred Hutchinson Cancer Center | CHIMERIC RECEPTOR PROTEINS AND THEIR USES |
| CN115210252A (zh) | 2020-02-04 | 2022-10-18 | 西雅图儿童医院（Dba西雅图儿童研究所） | 抗二硝基苯酚的嵌合抗原受体 |
| MX2022010340A (es) | 2020-02-24 | 2022-09-19 | Allogene Therapeutics Inc | Celulas t con car de bcma con actividades mejoradas. |
| CN111269326A (zh) * | 2020-02-28 | 2020-06-12 | 南京北恒生物科技有限公司 | 新型嵌合抗原受体及其用途 |
| WO2022037625A1 (en) * | 2020-08-19 | 2022-02-24 | Shandong Boan Biotechnology Co., Ltd. | Stealth chimeric antigen receptor and use thereof in reducing cytotoxicity towards normal cells |
| EP4403580A1 (en) | 2023-01-23 | 2024-07-24 | Medizinische Hochschule Hannover | Anti-entpd3 chimeric antigen receptor |
| CN120981484A (zh) | 2023-01-23 | 2025-11-18 | 汉诺威医学院 | 抗entpd3嵌合抗原受体 |
| AU2024219048A1 (en) | 2023-02-07 | 2025-08-07 | Quell Therapeutics Limited | Culture method for treg cells |
| WO2024175805A1 (en) | 2023-02-24 | 2024-08-29 | Medizinische Hochschule Hannover | Chimeric antigen receptor |
| EP4420676A1 (en) | 2023-02-24 | 2024-08-28 | Medizinische Hochschule Hannover | Chimeric antigen receptor |
| WO2024194355A1 (en) | 2023-03-20 | 2024-09-26 | Medizinische Hochschule Hannover | Chimeric antigen receptor |
| EP4434539A1 (en) | 2023-03-20 | 2024-09-25 | Medizinische Hochschule Hannover | Chimeric antigen receptor |
| CN117903311B (zh) * | 2024-03-20 | 2024-10-25 | 湖南卓润生物科技有限公司 | sST2特异性结合蛋白及其制备方法和应用 |
| WO2026008994A1 (en) | 2024-07-04 | 2026-01-08 | Quell Therapeutics Limited | Expression construct |
| GB202411558D0 (en) | 2024-08-06 | 2024-09-18 | Quell Therapeutics Ltd | Culture method |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9809658D0 (en) | 1998-05-06 | 1998-07-01 | Celltech Therapeutics Ltd | Biological products |
| EP2126054B1 (en) | 2007-01-31 | 2016-07-06 | Yeda Research And Development Company Limited | Redirected, genetically-engineered t regulatory cells and their use in suppression of autoimmune and inflammatory disease |
| WO2012033885A1 (en) | 2010-09-08 | 2012-03-15 | Baylor College Of Medicine | Immunotherapy of cancer using genetically engineered gd2-specific t cells |
| CA2832569A1 (en) * | 2011-04-08 | 2012-10-11 | Baylor College Of Medicine | Reversing the effects of the tumor microenvironment using chimeric cytokine receptors |
| US10391126B2 (en) | 2011-11-18 | 2019-08-27 | Board Of Regents, The University Of Texas System | CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA |
| AU2013204922B2 (en) | 2012-12-20 | 2015-05-14 | Celgene Corporation | Chimeric antigen receptors |
| CN113005091A (zh) | 2013-02-06 | 2021-06-22 | 细胞基因公司 | 具有改进特异性的修饰的t淋巴细胞 |
| JP6493692B2 (ja) | 2013-03-15 | 2019-04-10 | セルジーン コーポレイション | 修飾されたｔリンパ球 |
| BR112017001183A2 (pt) * | 2014-07-21 | 2017-11-28 | Novartis Ag | tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado |
| TWI719942B (zh) * | 2014-07-21 | 2021-03-01 | 瑞士商諾華公司 | 使用ｃｄ３３嵌合抗原受體治療癌症 |
| WO2016127257A1 (en) * | 2015-02-12 | 2016-08-18 | University Health Network | Chimeric antigen receptors |
| WO2016134284A1 (en) * | 2015-02-19 | 2016-08-25 | University Of Florida Research Foundation, Inc. | Chimeric antigen receptors and uses thereof |
| US10786549B2 (en) | 2015-04-23 | 2020-09-29 | Baylor College Of Medicine | CD5 chimeric antigen receptor for adoptive T cell therapy |
| US11154572B2 (en) | 2015-06-05 | 2021-10-26 | Board Of Regents, The University Of Texas System | Methods of treatment with natural killer cells matched for killer immunoglobulin receptor type |
| GB201514875D0 (en) | 2015-08-20 | 2015-10-07 | Autolus Ltd | Receptor |
| GB201518816D0 (en) * | 2015-10-23 | 2015-12-09 | Autolus Ltd | Receptor |
-
2015
- 2015-10-23 GB GBGB1518816.2A patent/GB201518816D0/en not_active Ceased
-
2016
- 2016-10-21 US US15/770,110 patent/US11242377B2/en active Active
- 2016-10-21 WO PCT/GB2016/053290 patent/WO2017068360A1/en not_active Ceased
- 2016-10-21 EP EP16787536.8A patent/EP3364998A1/en not_active Withdrawn
- 2016-10-21 HK HK18111556.3A patent/HK1252163A1/zh unknown
- 2016-10-21 CA CA3001792A patent/CA3001792A1/en not_active Abandoned
- 2016-10-21 JP JP2018520157A patent/JP7082046B2/ja active Active
- 2016-10-21 CN CN201680061278.7A patent/CN108135988A/zh active Pending
- 2016-10-21 AU AU2016342560A patent/AU2016342560B2/en not_active Expired - Fee Related
-
2021
- 2021-12-22 US US17/560,022 patent/US20220275052A1/en active Pending
-
2022
- 2022-01-20 JP JP2022007006A patent/JP2022058681A/ja not_active Withdrawn
-
2023
- 2023-12-28 JP JP2023222448A patent/JP2024024014A/ja active Pending
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