JP2021528451A5 - - Google Patents

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Publication number
JP2021528451A5
JP2021528451A5 JP2020572372A JP2020572372A JP2021528451A5 JP 2021528451 A5 JP2021528451 A5 JP 2021528451A5 JP 2020572372 A JP2020572372 A JP 2020572372A JP 2020572372 A JP2020572372 A JP 2020572372A JP 2021528451 A5 JP2021528451 A5 JP 2021528451A5
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JP
Japan
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alkylene
alkyl
halo
independently selected
membered
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JP2020572372A
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English (en)
Japanese (ja)
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JP7214086B2 (ja
JP2021528451A (ja
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Priority claimed from PCT/EP2019/067351 external-priority patent/WO2020002611A1/en
Publication of JP2021528451A publication Critical patent/JP2021528451A/ja
Publication of JP2021528451A5 publication Critical patent/JP2021528451A5/ja
Application granted granted Critical
Publication of JP7214086B2 publication Critical patent/JP7214086B2/ja
Active legal-status Critical Current
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JP2020572372A 2018-06-28 2019-06-28 二環式コア部分を有する新規lxrモジュレーター Active JP7214086B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18180450.1 2018-06-28
EP18180450 2018-06-28
PCT/EP2019/067351 WO2020002611A1 (en) 2018-06-28 2019-06-28 Novel lxr modulators with bicyclic core moiety

Publications (3)

Publication Number Publication Date
JP2021528451A JP2021528451A (ja) 2021-10-21
JP2021528451A5 true JP2021528451A5 (enExample) 2022-06-16
JP7214086B2 JP7214086B2 (ja) 2023-01-30

Family

ID=62947921

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020572372A Active JP7214086B2 (ja) 2018-06-28 2019-06-28 二環式コア部分を有する新規lxrモジュレーター

Country Status (27)

Country Link
US (3) US11618747B2 (enExample)
EP (1) EP3814331B9 (enExample)
JP (1) JP7214086B2 (enExample)
KR (1) KR102678581B1 (enExample)
CN (1) CN112689630A (enExample)
AR (1) AR117599A1 (enExample)
AU (1) AU2019293727B2 (enExample)
BR (1) BR112020026405A2 (enExample)
CA (1) CA3104956C (enExample)
CL (1) CL2020003300A1 (enExample)
DK (1) DK3814331T3 (enExample)
EA (1) EA202092821A1 (enExample)
ES (1) ES2956045T3 (enExample)
FI (1) FI3814331T3 (enExample)
HU (1) HUE063538T2 (enExample)
IL (2) IL310623A (enExample)
LT (1) LT3814331T (enExample)
MX (1) MX2020014258A (enExample)
PH (1) PH12020552269A1 (enExample)
PL (1) PL3814331T3 (enExample)
PT (1) PT3814331T (enExample)
PY (1) PY1950412A (enExample)
SI (1) SI3814331T1 (enExample)
SM (1) SMT202300334T1 (enExample)
TW (1) TWI748194B (enExample)
UY (1) UY38283A (enExample)
WO (1) WO2020002611A1 (enExample)

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TWI748194B (zh) 2018-06-28 2021-12-01 德商菲尼克斯 Fxr有限責任公司 含有雙環核心部分之新穎lxr調節劑
CN115697969B (zh) 2020-04-03 2026-08-11 弗特克斯药品有限公司 α-1抗胰蛋白酶调节剂
AU2021247285A1 (en) 2020-04-03 2022-10-27 Vertex Pharmaceuticals Incorporated Modulators of alpha-1 antitrypsin
CA3177531A1 (en) * 2020-04-03 2021-10-07 Vertex Pharmaceuticals Incorporated Indole derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (aatd)
JP7732999B2 (ja) 2020-04-03 2025-09-02 バーテックス ファーマシューティカルズ インコーポレイテッド アルファ1-アンチトリプシンのモジュレーター
EP4188931A2 (en) 2020-07-27 2023-06-07 Vertex Pharmaceuticals Incorporated Processes for preparing modulators of alpha-1 antitrypsin
JP2025540601A (ja) * 2022-11-03 2025-12-16 オルソバイオ, インコーポレイテッド 脂質異常症を治療するための二環式のコア部分を有するlxr調節因子

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