JP2017534591A5 - - Google Patents

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Publication number
JP2017534591A5
JP2017534591A5 JP2017516735A JP2017516735A JP2017534591A5 JP 2017534591 A5 JP2017534591 A5 JP 2017534591A5 JP 2017516735 A JP2017516735 A JP 2017516735A JP 2017516735 A JP2017516735 A JP 2017516735A JP 2017534591 A5 JP2017534591 A5 JP 2017534591A5
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JP
Japan
Prior art keywords
alkyl
compound according
aryl
heteroaryl
disease
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JP2017516735A
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English (en)
Japanese (ja)
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JP6770511B2 (ja
JP2017534591A (ja
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Priority claimed from PCT/US2015/052611 external-priority patent/WO2016053855A1/en
Publication of JP2017534591A publication Critical patent/JP2017534591A/ja
Publication of JP2017534591A5 publication Critical patent/JP2017534591A5/ja
Application granted granted Critical
Publication of JP6770511B2 publication Critical patent/JP6770511B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017516735A 2014-09-29 2015-09-28 心肺障害の処置のためのスフィンゴシン−1−リン酸受容体モジュレーター Expired - Fee Related JP6770511B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462056946P 2014-09-29 2014-09-29
US62/056,946 2014-09-29
PCT/US2015/052611 WO2016053855A1 (en) 2014-09-29 2015-09-28 Sphingosine-1-phospate receptor modulators for treatment of cardiopulmonary disorders

Publications (3)

Publication Number Publication Date
JP2017534591A JP2017534591A (ja) 2017-11-24
JP2017534591A5 true JP2017534591A5 (enExample) 2018-10-25
JP6770511B2 JP6770511B2 (ja) 2020-10-14

Family

ID=55631308

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017516735A Expired - Fee Related JP6770511B2 (ja) 2014-09-29 2015-09-28 心肺障害の処置のためのスフィンゴシン−1−リン酸受容体モジュレーター

Country Status (13)

Country Link
US (2) US10323029B2 (enExample)
EP (1) EP3209732B1 (enExample)
JP (1) JP6770511B2 (enExample)
KR (1) KR102307037B1 (enExample)
CN (1) CN107001806B (enExample)
AU (1) AU2015324163B2 (enExample)
CA (1) CA2962922C (enExample)
EA (1) EA031503B1 (enExample)
ES (1) ES2895174T3 (enExample)
IL (1) IL251387B (enExample)
SG (1) SG11201702483QA (enExample)
WO (1) WO2016053855A1 (enExample)
ZA (1) ZA201702403B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015324163B2 (en) 2014-09-29 2020-06-25 The Scripps Research Institute Sphingosine-1-phospate receptor modulators for treatment of cardiopulmonary disorders
WO2017144183A1 (en) * 2016-02-24 2017-08-31 Acesion Pharma Aps Novel potassium channel inhibitors
US11049009B2 (en) * 2017-06-12 2021-06-29 Western Digital Technologies, Inc. Identifying memory block write endurance using machine learning
US20200316021A1 (en) * 2017-09-29 2020-10-08 Novartis Ag Dosing Regimen of Siponimod
CN112469697B (zh) * 2018-07-11 2025-02-14 鲁贝多生命科学公司 抗衰老组合物及其用途
KR102218280B1 (ko) * 2019-01-30 2021-02-22 주식회사 엑세쏘바이오파마 P1p 유도체의 패혈증 치료제 용도
AU2020267356B2 (en) * 2019-05-03 2025-04-24 Praxis Precision Medicines, Inc. KCNT1 inhibitors and methods of use
CN113200971B (zh) * 2021-05-14 2022-06-28 济南大学 一类具有芳香基哌嗪结构的吲哚恶二唑衍生物的合成和应用
EP4342882A4 (en) * 2021-05-17 2024-08-28 HK inno.N Corporation BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING IT AS ACTIVE INGREDIENT
WO2025176104A1 (en) 2024-02-19 2025-08-28 Ono Pharmaceutical Co., Ltd. Heterocyclic derivatives having s1p3 receptor antagonistic activity

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US3217012A (en) * 1960-10-26 1965-11-09 Purdue Research Foundation Substituted pyridines, process for and new compositions
US3916000A (en) * 1971-07-21 1975-10-28 Commw Scient Ind Res Org Alkylation process
EP0355864A3 (en) * 1984-03-15 1991-09-18 Wako Pure Chemical Industries, Ltd. Method of quantitatively measuring an oxidative substance by using triphenyl methane type leuco compounds as coloring matter
US6028103A (en) * 1994-09-16 2000-02-22 Children's Medical Center Corporation Triaryl methane compounds and analogues thereof useful for the treatment or prevention of sickle cell disease or diseases characterized by abnormal cell proliferation
US20020156301A1 (en) * 1997-06-17 2002-10-24 Sumitomo Chemical Co., Ltd. Triphenylmethane derivatives and use thereof
JP4709488B2 (ja) * 2002-01-18 2011-06-22 メルク・シャープ・エンド・ドーム・コーポレイション Edg受容体作動薬としてのN−(ベンジル)アミノアルキルカルボン酸化合物、ホスフィン酸化合物、ホスホン酸化合物およびテトラゾール類
US20060287537A1 (en) * 2003-08-27 2006-12-21 Stanislav Radl Method of removing the triphenylmethane protecting group
CN101528699A (zh) * 2005-11-23 2009-09-09 布里斯托尔—迈尔斯斯奎布公司 杂环胆固醇酯转运蛋白抑制剂
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US8445686B2 (en) 2007-08-27 2013-05-21 Abbvie Inc. 4-(4-pyridinyl)-benzamides and their use as rock activity modulators
WO2009117269A1 (en) * 2008-03-18 2009-09-24 Merck & Co., Inc. Substituted 4-hydroxypyrimidine-5-carboxamides
EP2297117B1 (en) * 2008-05-19 2012-10-31 Merck Sharp & Dohme Corp. Bicyclic heterocycle derivatives and use thereof as gpr119 modulators
WO2010014948A1 (en) * 2008-08-01 2010-02-04 The University Of Utah Research Foundation Methods of treatment using wnt inhibitors
WO2010056758A1 (en) * 2008-11-12 2010-05-20 Yangbo Feng Quinazoline derivatives as kinase inhibitors
JP2013028538A (ja) * 2009-11-13 2013-02-07 Dainippon Sumitomo Pharma Co Ltd 新規アミド誘導体
CN103338764A (zh) * 2010-12-03 2013-10-02 阿勒根公司 作为鞘氨醇1-磷酸(s1p)受体调节剂的新型氮杂环丁烷衍生物
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KR20130133234A (ko) 2010-12-03 2013-12-06 알러간, 인코포레이티드 스핑고신 1-포스페이트 (s1p) 수용체 조절제로서의 신규한 피리딘 유도체
CA2839699A1 (en) * 2011-06-24 2012-12-27 Amgen Inc. Trpm8 antagonists and their use in treatments
DE202013011832U1 (de) * 2012-04-11 2014-07-25 Fluoron Gmbh Färbemittel
US9410058B2 (en) 2014-04-10 2016-08-09 United States Gypsum Company Compositions and methods for water-resistant gypsum fiber products
AU2015324163B2 (en) 2014-09-29 2020-06-25 The Scripps Research Institute Sphingosine-1-phospate receptor modulators for treatment of cardiopulmonary disorders

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