JP2017534591A5 - - Google Patents

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Publication number
JP2017534591A5
JP2017534591A5 JP2017516735A JP2017516735A JP2017534591A5 JP 2017534591 A5 JP2017534591 A5 JP 2017534591A5 JP 2017516735 A JP2017516735 A JP 2017516735A JP 2017516735 A JP2017516735 A JP 2017516735A JP 2017534591 A5 JP2017534591 A5 JP 2017534591A5
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JP
Japan
Prior art keywords
alkyl
compound according
aryl
heteroaryl
disease
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JP2017516735A
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English (en)
Japanese (ja)
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JP6770511B2 (ja
JP2017534591A (ja
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Priority claimed from PCT/US2015/052611 external-priority patent/WO2016053855A1/en
Publication of JP2017534591A publication Critical patent/JP2017534591A/ja
Publication of JP2017534591A5 publication Critical patent/JP2017534591A5/ja
Application granted granted Critical
Publication of JP6770511B2 publication Critical patent/JP6770511B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017516735A 2014-09-29 2015-09-28 心肺障害の処置のためのスフィンゴシン−1−リン酸受容体モジュレーター Expired - Fee Related JP6770511B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462056946P 2014-09-29 2014-09-29
US62/056,946 2014-09-29
PCT/US2015/052611 WO2016053855A1 (en) 2014-09-29 2015-09-28 Sphingosine-1-phospate receptor modulators for treatment of cardiopulmonary disorders

Publications (3)

Publication Number Publication Date
JP2017534591A JP2017534591A (ja) 2017-11-24
JP2017534591A5 true JP2017534591A5 (enExample) 2018-10-25
JP6770511B2 JP6770511B2 (ja) 2020-10-14

Family

ID=55631308

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017516735A Expired - Fee Related JP6770511B2 (ja) 2014-09-29 2015-09-28 心肺障害の処置のためのスフィンゴシン−1−リン酸受容体モジュレーター

Country Status (13)

Country Link
US (2) US10323029B2 (enExample)
EP (1) EP3209732B1 (enExample)
JP (1) JP6770511B2 (enExample)
KR (1) KR102307037B1 (enExample)
CN (1) CN107001806B (enExample)
AU (1) AU2015324163B2 (enExample)
CA (1) CA2962922C (enExample)
EA (1) EA031503B1 (enExample)
ES (1) ES2895174T3 (enExample)
IL (1) IL251387B (enExample)
SG (1) SG11201702483QA (enExample)
WO (1) WO2016053855A1 (enExample)
ZA (1) ZA201702403B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2962922C (en) 2014-09-29 2021-10-26 The Scripps Research Institute Sphingosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders
CN109153667B (zh) * 2016-02-24 2021-04-02 阿塞西翁制药公司 新型钾通道抑制剂
US11049009B2 (en) * 2017-06-12 2021-06-29 Western Digital Technologies, Inc. Identifying memory block write endurance using machine learning
WO2019064212A1 (en) * 2017-09-29 2019-04-04 Novartis Ag DOSAGE DIAGRAM OF SIPONIMOD
MX2021000395A (es) * 2018-07-11 2021-05-12 Rubedo Life Sciences Inc Composiciones senolíticas y usos de las mismas.
KR102218280B1 (ko) * 2019-01-30 2021-02-22 주식회사 엑세쏘바이오파마 P1p 유도체의 패혈증 치료제 용도
CN120817941A (zh) * 2019-05-03 2025-10-21 普拉克西斯精密药物股份有限公司 Kcnt1抑制剂和使用方法
CN113200971B (zh) * 2021-05-14 2022-06-28 济南大学 一类具有芳香基哌嗪结构的吲哚恶二唑衍生物的合成和应用
MX2023013690A (es) * 2021-05-17 2024-01-30 Hk Inno N Corp Derivado de benzamida, metodo para preparar el mismo, y composicion farmaceutica para la prevencion o tratamiento del cancer que contiene el mismo como ingrediente activo.
WO2025176104A1 (en) 2024-02-19 2025-08-28 Ono Pharmaceutical Co., Ltd. Heterocyclic derivatives having s1p3 receptor antagonistic activity

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2085736A (en) * 1933-12-06 1937-07-06 Du Pont Compounds of the triphenylmethane series
US3217012A (en) * 1960-10-26 1965-11-09 Purdue Research Foundation Substituted pyridines, process for and new compositions
US3916000A (en) * 1971-07-21 1975-10-28 Commw Scient Ind Res Org Alkylation process
EP0355864A3 (en) * 1984-03-15 1991-09-18 Wako Pure Chemical Industries, Ltd. Method of quantitatively measuring an oxidative substance by using triphenyl methane type leuco compounds as coloring matter
US6028103A (en) * 1994-09-16 2000-02-22 Children's Medical Center Corporation Triaryl methane compounds and analogues thereof useful for the treatment or prevention of sickle cell disease or diseases characterized by abnormal cell proliferation
US20020156301A1 (en) * 1997-06-17 2002-10-24 Sumitomo Chemical Co., Ltd. Triphenylmethane derivatives and use thereof
ATE448193T1 (de) * 2002-01-18 2009-11-15 Merck & Co Inc ßN-(BENZYL)AMINOALKYL CARBOXYLATE, PHOSPHINATE, PHOSPHONATE UND TETRAZOLE ALS EDG REZEPTORAGONISTENß
ES2348300T3 (es) * 2003-08-27 2010-12-02 Zentiva, K.S. Procedimiento para eliminar el grupo protector trifenilmetano.
US7888376B2 (en) * 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
CN101528699A (zh) * 2005-11-23 2009-09-09 布里斯托尔—迈尔斯斯奎布公司 杂环胆固醇酯转运蛋白抑制剂
US7947712B2 (en) * 2006-08-23 2011-05-24 Wyeth Llc 8-hydroxyquinoline compounds and methods thereof
US8445686B2 (en) 2007-08-27 2013-05-21 Abbvie Inc. 4-(4-pyridinyl)-benzamides and their use as rock activity modulators
AU2009225869B2 (en) * 2008-03-18 2014-01-23 Merck Sharp & Dohme Llc Substituted 4-hydroxypyrimidine-5-carboxamides
CA2724426A1 (en) * 2008-05-19 2009-11-26 Schering Corporation Bicyclic heterocycle derivatives and use thereof as gpr119 modulators
WO2010014948A1 (en) * 2008-08-01 2010-02-04 The University Of Utah Research Foundation Methods of treatment using wnt inhibitors
WO2010056758A1 (en) * 2008-11-12 2010-05-20 Yangbo Feng Quinazoline derivatives as kinase inhibitors
JP2013028538A (ja) * 2009-11-13 2013-02-07 Dainippon Sumitomo Pharma Co Ltd 新規アミド誘導体
JP2013544831A (ja) 2010-12-03 2013-12-19 アラーガン インコーポレイテッド スフィンゴシン−1−リン酸(s1p)受容体モジュレーターとしての新規アゼチジン誘導体
JP2013544833A (ja) 2010-12-03 2013-12-19 アラーガン インコーポレイテッド スフィンゴシン−1−リン酸(s1p)受容体モジュレーターとしての新規ピリジン誘導体
AU2011337004A1 (en) * 2010-12-03 2013-07-11 Allergan, Inc. Novel phenyl oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators
AP2013007331A0 (en) * 2011-06-24 2013-12-31 Amgen Inc TRPM8 antagonists and their use in treatments
DE202013011832U1 (de) * 2012-04-11 2014-07-25 Fluoron Gmbh Färbemittel
US9410058B2 (en) 2014-04-10 2016-08-09 United States Gypsum Company Compositions and methods for water-resistant gypsum fiber products
CA2962922C (en) 2014-09-29 2021-10-26 The Scripps Research Institute Sphingosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders

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