JP2021535207A5 - - Google Patents
Info
- Publication number
- JP2021535207A5 JP2021535207A5 JP2021533405A JP2021533405A JP2021535207A5 JP 2021535207 A5 JP2021535207 A5 JP 2021535207A5 JP 2021533405 A JP2021533405 A JP 2021533405A JP 2021533405 A JP2021533405 A JP 2021533405A JP 2021535207 A5 JP2021535207 A5 JP 2021535207A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound according
- alkyl
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024187991A JP7846735B2 (ja) | 2018-08-24 | 2024-10-25 | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
| JP2026061675A JP2026117048A (ja) | 2018-08-24 | 2026-04-03 | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862722312P | 2018-08-24 | 2018-08-24 | |
| US62/722,312 | 2018-08-24 | ||
| US201962867117P | 2019-06-26 | 2019-06-26 | |
| US62/867,117 | 2019-06-26 | ||
| PCT/US2019/047968 WO2020041741A1 (en) | 2018-08-24 | 2019-08-23 | Thyroid hormone receptor beta agonist compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024187991A Division JP7846735B2 (ja) | 2018-08-24 | 2024-10-25 | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021535207A JP2021535207A (ja) | 2021-12-16 |
| JP2021535207A5 true JP2021535207A5 (enExample) | 2022-08-30 |
| JP7579253B2 JP7579253B2 (ja) | 2024-11-07 |
Family
ID=69584321
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021533405A Active JP7579253B2 (ja) | 2018-08-24 | 2019-08-23 | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
| JP2024187991A Active JP7846735B2 (ja) | 2018-08-24 | 2024-10-25 | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
| JP2026061675A Pending JP2026117048A (ja) | 2018-08-24 | 2026-04-03 | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024187991A Active JP7846735B2 (ja) | 2018-08-24 | 2024-10-25 | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
| JP2026061675A Pending JP2026117048A (ja) | 2018-08-24 | 2026-04-03 | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10800767B2 (enExample) |
| EP (2) | EP4755882A3 (enExample) |
| JP (3) | JP7579253B2 (enExample) |
| CN (2) | CN122562793A (enExample) |
| AU (2) | AU2019325656B2 (enExample) |
| CA (1) | CA3110520A1 (enExample) |
| DK (1) | DK3840755T3 (enExample) |
| ES (1) | ES3070127T3 (enExample) |
| MA (1) | MA53448A (enExample) |
| TW (1) | TWI837169B (enExample) |
| WO (1) | WO2020041741A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI884745B (zh) | 2018-10-12 | 2025-05-21 | 美商拓臻股份有限公司 | 甲狀腺素受體β促效劑化合物 |
| CN121081472A (zh) | 2018-12-13 | 2025-12-09 | 拓臻股份有限公司 | 一种THRβ受体激动剂化合物及其制备方法和用途 |
| WO2020227549A1 (en) | 2019-05-08 | 2020-11-12 | Aligos Therapeutics, Inc. | MODULATORS OF THR-β AND METHODS OF USE THEREOF |
| WO2020228577A1 (zh) * | 2019-05-10 | 2020-11-19 | 深圳微芯生物科技股份有限公司 | 一种哒嗪酮衍生物及其应用 |
| CA3154488A1 (en) | 2019-08-23 | 2021-03-04 | Terns Pharmaceuticals, Inc. | Thyroid hormone receptor beta agonist compounds |
| CA3154391A1 (en) * | 2019-09-12 | 2021-03-18 | Terns Pharmaceuticals, Inc. | Thyroid hormone receptor beta agonist compounds |
| JP2023537271A (ja) | 2020-07-24 | 2023-08-31 | イニファーム，インク． | チオフェンｈｓｄ１７ｂ１３阻害剤とその使用 |
| CN114437034A (zh) * | 2020-11-06 | 2022-05-06 | 深圳微芯生物科技股份有限公司 | 一种酞嗪类化合物的可药用盐、晶型及其制备方法 |
| CN116670118B (zh) | 2020-11-13 | 2026-02-06 | 伊尼制药公司 | 二氯苯酚hsd17b13抑制剂及其用途 |
| CN114621207B (zh) * | 2020-12-11 | 2025-02-11 | 广东东阳光药业股份有限公司 | 一种作为甲状腺激素β受体激动剂的化合物及其用途 |
| JP2024510935A (ja) * | 2021-03-03 | 2024-03-12 | ターンズ・ファーマシューティカルズ・インコーポレイテッド | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
| US20240239761A1 (en) * | 2021-03-19 | 2024-07-18 | Medshine Discovery Inc. | Bicyclic phenol compounds and use thereof |
| CN116940566A (zh) * | 2021-03-19 | 2023-10-24 | 南京明德新药研发有限公司 | 双环吡啶酮类化合物及其应用 |
| US12617772B2 (en) | 2021-04-05 | 2026-05-05 | Inipharm, Inc. | Hydroxypyridine HSD17B13 inhibitors and uses thereof |
| PE20252787A1 (es) | 2023-04-07 | 2025-12-22 | Terns Pharmaceuticals Inc | Combinacion que comprende un agonista de thr-beta y un agonista de glp-1r para su uso en el tratamiento de un trastorno hepatico o una enfermedad cardiometabolica |
| CN116554063B (zh) * | 2023-05-23 | 2025-03-07 | 江苏省农用激素工程技术研究中心有限公司 | 氟胺磺隆中间体的制备方法 |
| WO2026092583A1 (en) | 2024-10-30 | 2026-05-07 | Ascletis Pharma (China) Co., Limited | Thr-beta modulators, alone or in combination with glp-1r\gipr\gcgr modulators for the treatment of metabolic diseases and alopecia areata diseases |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2473162A1 (en) * | 2002-01-30 | 2003-08-07 | Kissei Pharmaceutical Co., Ltd. | Novel thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof |
| US7572799B2 (en) * | 2003-11-24 | 2009-08-11 | Pfizer Inc | Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors |
| GB0327319D0 (en) * | 2003-11-24 | 2003-12-24 | Pfizer Ltd | Novel pharmaceuticals |
| ATE480524T1 (de) * | 2005-07-21 | 2010-09-15 | Hoffmann La Roche | Pyridazinonderivate als schilddrüsenhormon- rezeptoragonisten |
| WO2007132475A1 (en) | 2006-05-15 | 2007-11-22 | Cadila Healthcare Limited | Selective tr-beta 1 agonist |
| WO2008130637A1 (en) * | 2007-04-18 | 2008-10-30 | New York University | Hydrazide compounds as thyroid hormone receptor modulators and uses thereof |
| TWI698430B (zh) * | 2015-02-13 | 2020-07-11 | 南北兄弟藥業投資有限公司 | 三環化合物及其在藥物中的應用 |
| CN109574995B (zh) | 2018-01-23 | 2020-07-24 | 深圳市塔吉瑞生物医药有限公司 | 取代的哒嗪酮化合物 |
| ES3029158T3 (en) | 2018-06-12 | 2025-06-23 | Xizang Haisco Pharmaceutical Co Ltd | Thyroid hormone receptor agonists and uses thereof |
| CN119552152A (zh) | 2018-10-12 | 2025-03-04 | 益方生物科技(上海)股份有限公司 | 甲状腺激素受体激动剂 |
-
2019
- 2019-08-23 WO PCT/US2019/047968 patent/WO2020041741A1/en not_active Ceased
- 2019-08-23 MA MA053448A patent/MA53448A/fr unknown
- 2019-08-23 CN CN202610545235.1A patent/CN122562793A/zh active Pending
- 2019-08-23 DK DK19852050.4T patent/DK3840755T3/da active
- 2019-08-23 EP EP26158747.1A patent/EP4755882A3/en active Pending
- 2019-08-23 AU AU2019325656A patent/AU2019325656B2/en active Active
- 2019-08-23 US US16/549,979 patent/US10800767B2/en active Active
- 2019-08-23 ES ES19852050T patent/ES3070127T3/es active Active
- 2019-08-23 JP JP2021533405A patent/JP7579253B2/ja active Active
- 2019-08-23 TW TW108130298A patent/TWI837169B/zh active
- 2019-08-23 EP EP19852050.4A patent/EP3840755B1/en active Active
- 2019-08-23 CA CA3110520A patent/CA3110520A1/en active Pending
- 2019-08-23 CN CN201980066702.0A patent/CN112805005B/zh active Active
-
2024
- 2024-08-29 US US18/818,705 patent/US20250236615A1/en active Pending
- 2024-10-25 JP JP2024187991A patent/JP7846735B2/ja active Active
-
2025
- 2025-07-22 AU AU2025206402A patent/AU2025206402A1/en active Pending
-
2026
- 2026-04-03 JP JP2026061675A patent/JP2026117048A/ja active Pending
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