JP2021535207A5 - - Google Patents

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Publication number
JP2021535207A5
JP2021535207A5 JP2021533405A JP2021533405A JP2021535207A5 JP 2021535207 A5 JP2021535207 A5 JP 2021535207A5 JP 2021533405 A JP2021533405 A JP 2021533405A JP 2021533405 A JP2021533405 A JP 2021533405A JP 2021535207 A5 JP2021535207 A5 JP 2021535207A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
compound according
alkyl
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2021533405A
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English (en)
Japanese (ja)
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JP7579253B2 (ja
JP2021535207A (ja
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Priority claimed from PCT/US2019/047968 external-priority patent/WO2020041741A1/en
Publication of JP2021535207A publication Critical patent/JP2021535207A/ja
Publication of JP2021535207A5 publication Critical patent/JP2021535207A5/ja
Priority to JP2024187991A priority Critical patent/JP7846735B2/ja
Application granted granted Critical
Publication of JP7579253B2 publication Critical patent/JP7579253B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021533405A 2018-08-24 2019-08-23 甲状腺ホルモン受容体ベータアゴニスト化合物 Active JP7579253B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024187991A JP7846735B2 (ja) 2018-08-24 2024-10-25 甲状腺ホルモン受容体ベータアゴニスト化合物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862722312P 2018-08-24 2018-08-24
US62/722,312 2018-08-24
US201962867117P 2019-06-26 2019-06-26
US62/867,117 2019-06-26
PCT/US2019/047968 WO2020041741A1 (en) 2018-08-24 2019-08-23 Thyroid hormone receptor beta agonist compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024187991A Division JP7846735B2 (ja) 2018-08-24 2024-10-25 甲状腺ホルモン受容体ベータアゴニスト化合物

Publications (3)

Publication Number Publication Date
JP2021535207A JP2021535207A (ja) 2021-12-16
JP2021535207A5 true JP2021535207A5 (enExample) 2022-08-30
JP7579253B2 JP7579253B2 (ja) 2024-11-07

Family

ID=69584321

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021533405A Active JP7579253B2 (ja) 2018-08-24 2019-08-23 甲状腺ホルモン受容体ベータアゴニスト化合物
JP2024187991A Active JP7846735B2 (ja) 2018-08-24 2024-10-25 甲状腺ホルモン受容体ベータアゴニスト化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024187991A Active JP7846735B2 (ja) 2018-08-24 2024-10-25 甲状腺ホルモン受容体ベータアゴニスト化合物

Country Status (9)

Country Link
US (2) US10800767B2 (enExample)
EP (1) EP3840755B1 (enExample)
JP (2) JP7579253B2 (enExample)
CN (1) CN112805005A (enExample)
AU (2) AU2019325656B2 (enExample)
CA (1) CA3110520A1 (enExample)
MA (1) MA53448A (enExample)
TW (1) TWI837169B (enExample)
WO (1) WO2020041741A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI884745B (zh) 2018-10-12 2025-05-21 美商拓臻股份有限公司 甲狀腺素受體β促效劑化合物
CN111320609A (zh) 2018-12-13 2020-06-23 拓臻股份有限公司 一种THRβ受体激动剂化合物及其制备方法和用途
KR20220017917A (ko) 2019-05-08 2022-02-14 알리고스 테라퓨틱스 인코포레이티드 Thr-베타의 조절제 및 이의 사용 방법
WO2020228577A1 (zh) * 2019-05-10 2020-11-19 深圳微芯生物科技股份有限公司 一种哒嗪酮衍生物及其应用
AU2020336272A1 (en) 2019-08-23 2022-04-14 Terns Pharmaceuticals, Inc. Thyroid hormone receptor beta agonist compounds
WO2021050945A1 (en) * 2019-09-12 2021-03-18 Terns, Inc. Thyroid hormone receptor beta agonist compounds
CN114437034A (zh) * 2020-11-06 2022-05-06 深圳微芯生物科技股份有限公司 一种酞嗪类化合物的可药用盐、晶型及其制备方法
AU2021377248B2 (en) * 2020-11-13 2025-12-18 Inipharm, Inc. Dichlorophenol hsd17b13 inhibitors and uses thereof
CN114621207B (zh) * 2020-12-11 2025-02-11 广东东阳光药业股份有限公司 一种作为甲状腺激素β受体激动剂的化合物及其用途
PE20240097A1 (es) * 2021-03-03 2024-01-18 Terns Pharmaceuticals Inc Compuestos agonistas beta del receptor de la hormona tiroidea
WO2022194278A1 (zh) * 2021-03-19 2022-09-22 南京明德新药研发有限公司 双环苯酚类化合物及其应用
CN116940566A (zh) * 2021-03-19 2023-10-24 南京明德新药研发有限公司 双环吡啶酮类化合物及其应用
EP4568664B1 (en) 2023-04-07 2026-04-01 Terns Pharmaceuticals, Inc. Combination comprising a thr-beta agonist and a glp-1r agonist for use in treating obesity
CN116554063B (zh) * 2023-05-23 2025-03-07 江苏省农用激素工程技术研究中心有限公司 氟胺磺隆中间体的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1471049A4 (en) 2002-01-30 2006-08-16 Kissei Pharmaceutical NEW THYROIDIAN HORMONE RECEPTOR LIGAND, MEDICINAL PREPARATIONS CONTAINING THE SAME AND USE THEREOF
US7572799B2 (en) * 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
GB0327319D0 (en) 2003-11-24 2003-12-24 Pfizer Ltd Novel pharmaceuticals
DK1919878T3 (da) * 2005-07-21 2010-10-25 Hoffmann La Roche Pyridazinonderivater som thyroidhormonreceptoragonister
WO2007132475A1 (en) * 2006-05-15 2007-11-22 Cadila Healthcare Limited Selective tr-beta 1 agonist
WO2008130637A1 (en) * 2007-04-18 2008-10-30 New York University Hydrazide compounds as thyroid hormone receptor modulators and uses thereof
TWI698430B (zh) * 2015-02-13 2020-07-11 南北兄弟藥業投資有限公司 三環化合物及其在藥物中的應用
JP7156722B2 (ja) 2018-01-23 2022-10-19 深▲チェン▼市塔吉瑞生物医薬有限公司 置換ピリダジノン化合物
ES3029158T3 (en) 2018-06-12 2025-06-23 Xizang Haisco Pharmaceutical Co Ltd Thyroid hormone receptor agonists and uses thereof
CA3113373A1 (en) 2018-10-12 2020-04-16 InventisBio Co., Ltd. Thyroid hormone receptor agonists

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