JP2021523934A5 - - Google Patents

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Publication number
JP2021523934A5
JP2021523934A5 JP2021506391A JP2021506391A JP2021523934A5 JP 2021523934 A5 JP2021523934 A5 JP 2021523934A5 JP 2021506391 A JP2021506391 A JP 2021506391A JP 2021506391 A JP2021506391 A JP 2021506391A JP 2021523934 A5 JP2021523934 A5 JP 2021523934A5
Authority
JP
Japan
Prior art keywords
alkyl
compound
salt
phenyl
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021506391A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021523934A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/028560 external-priority patent/WO2019204819A1/en
Publication of JP2021523934A publication Critical patent/JP2021523934A/ja
Publication of JP2021523934A5 publication Critical patent/JP2021523934A5/ja
Pending legal-status Critical Current

Links

JP2021506391A 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なアミノピラジンおよび関連化合物 Pending JP2021523934A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862660880P 2018-04-20 2018-04-20
US62/660,880 2018-04-20
PCT/US2019/028560 WO2019204819A1 (en) 2018-04-20 2019-04-22 Aminopyrazines and related compounds useful as mitochondrial uncouplers

Publications (2)

Publication Number Publication Date
JP2021523934A JP2021523934A (ja) 2021-09-09
JP2021523934A5 true JP2021523934A5 (enExample) 2022-04-25

Family

ID=67139787

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2021506390A Pending JP2021523933A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なイミダゾピリジン
JP2021506391A Pending JP2021523934A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なアミノピラジンおよび関連化合物
JP2021506388A Pending JP2021522327A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なオキサジアゾロピラジンおよびオキサジアゾロピリジン

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021506390A Pending JP2021523933A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なイミダゾピリジン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021506388A Pending JP2021522327A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なオキサジアゾロピラジンおよびオキサジアゾロピリジン

Country Status (12)

Country Link
US (3) US11708376B2 (enExample)
EP (3) EP3781165A4 (enExample)
JP (3) JP2021523933A (enExample)
KR (3) KR20210003831A (enExample)
CN (3) CN112262141A (enExample)
AU (2) AU2019256719A1 (enExample)
BR (2) BR112020021466A2 (enExample)
CA (2) CA3097752A1 (enExample)
IL (2) IL278070A (enExample)
MX (2) MX2020011049A (enExample)
WO (3) WO2019204819A1 (enExample)
ZA (2) ZA202006295B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
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US11708376B2 (en) * 2018-04-20 2023-07-25 Virginia Tech Intellectual Properties, Inc. Substituted imidazo[4,5-b]pyridines, imidazo[4,5-b]pyrazines, and oxazolo[4,5- b]pyrazines as mitochondrial uncouplers
WO2020191503A1 (en) * 2019-03-27 2020-10-01 Algernon Pharmaceuticals Inc. Methods and uses of bromantane and derivatives thereof for treating lung disease, fatty liver disease, and kidney disorders
JP2023533016A (ja) 2020-07-11 2023-08-01 ファイザー・インク 抗ウイルス性ヘテロアリールケトン誘導体
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds
EP4482494A4 (en) * 2022-02-21 2026-02-25 Univ Colorado Regents RE-SENSITIZATION OF MULTI-DRUG-RESISTANT GRAM-NEGATIVE (MDR) BACTERIA TO COLISTIN USING IONOPHORES

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EP2863910B1 (en) 2012-06-20 2020-03-11 University Of Virginia Patent Foundation Compositions and methods for regulating glucose homeostasis and insulin action
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US11896591B2 (en) * 2017-05-22 2024-02-13 University Of Virginia Patent Foundation Compositions and methods for preparing and using mitochondrial uncouplers
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