JP2010540462A5 - - Google Patents

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Publication number
JP2010540462A5
JP2010540462A5 JP2010526066A JP2010526066A JP2010540462A5 JP 2010540462 A5 JP2010540462 A5 JP 2010540462A5 JP 2010526066 A JP2010526066 A JP 2010526066A JP 2010526066 A JP2010526066 A JP 2010526066A JP 2010540462 A5 JP2010540462 A5 JP 2010540462A5
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Japan
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substituted
unsubstituted
hydroxy
carbonyl
alkyl
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JP2010526066A
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Japanese (ja)
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JP2010540462A (ja
JP5055432B2 (ja
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Priority claimed from PCT/US2008/077537 external-priority patent/WO2009042694A1/en
Publication of JP2010540462A publication Critical patent/JP2010540462A/ja
Publication of JP2010540462A5 publication Critical patent/JP2010540462A5/ja
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Publication of JP5055432B2 publication Critical patent/JP5055432B2/ja
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JP2010526066A 2007-09-24 2008-09-24 治療のためのβ−セクレターゼ阻害剤としての(3−ヒドロキシ−4−アミノブタン−2−イル)−3−(2−チアゾール−2−イル−ピロリジン−1−カルボニル)ベンズアミド誘導体及び関連する化合物 Expired - Fee Related JP5055432B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97479307P 2007-09-24 2007-09-24
US60/974,793 2007-09-24
PCT/US2008/077537 WO2009042694A1 (en) 2007-09-24 2008-09-24 (3-hydroxy-4-amino-butan-2-yl) -3- (2-thiazol-2-yl-pyrrolidine-1-carbonyl) benzamide derivatives and related compounds as beta-secretase inhibitors for treating

Publications (3)

Publication Number Publication Date
JP2010540462A JP2010540462A (ja) 2010-12-24
JP2010540462A5 true JP2010540462A5 (enExample) 2011-11-10
JP5055432B2 JP5055432B2 (ja) 2012-10-24

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ID=40343545

Family Applications (1)

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JP2010526066A Expired - Fee Related JP5055432B2 (ja) 2007-09-24 2008-09-24 治療のためのβ−セクレターゼ阻害剤としての(3−ヒドロキシ−4−アミノブタン−2−イル)−3−(2−チアゾール−2−イル−ピロリジン−1−カルボニル)ベンズアミド誘導体及び関連する化合物

Country Status (8)

Country Link
US (1) US8299267B2 (enExample)
EP (1) EP2205596A1 (enExample)
JP (1) JP5055432B2 (enExample)
KR (1) KR20100059919A (enExample)
CN (1) CN101868457B (enExample)
CA (1) CA2699787A1 (enExample)
MX (1) MX2010002938A (enExample)
WO (1) WO2009042694A1 (enExample)

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CN105669365B (zh) * 2016-03-04 2022-06-21 中国科学院上海有机化学研究所 含二氟烷基取代的芳基或杂芳基化合物、制备方法和应用
DK3461819T3 (da) 2017-09-29 2020-08-10 Probiodrug Ag Inhibitorer af glutaminylcyklase
CN110117237B (zh) * 2018-02-05 2024-02-02 中国科学院上海有机化学研究所 一种芳香腈或烯基腈类化合物的制备方法
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