JP2007502264A5 - - Google Patents

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Publication number
JP2007502264A5
JP2007502264A5 JP2006523062A JP2006523062A JP2007502264A5 JP 2007502264 A5 JP2007502264 A5 JP 2007502264A5 JP 2006523062 A JP2006523062 A JP 2006523062A JP 2006523062 A JP2006523062 A JP 2006523062A JP 2007502264 A5 JP2007502264 A5 JP 2007502264A5
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JP
Japan
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nhc
compound according
independently
compound
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JP2006523062A
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English (en)
Japanese (ja)
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JP2007502264A (ja
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Priority claimed from GBGB0319124.4A external-priority patent/GB0319124D0/en
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Publication of JP2007502264A publication Critical patent/JP2007502264A/ja
Publication of JP2007502264A5 publication Critical patent/JP2007502264A5/ja
Withdrawn legal-status Critical Current

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JP2006523062A 2003-08-14 2004-08-13 Ｈｍ７４ａ受容体アゴニストとしての２−置換安息香酸誘導体 Withdrawn JP2007502264A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0319124.4A GB0319124D0 (en) 2003-08-14 2003-08-14 Chemical compounds
PCT/GB2004/003528 WO2005016870A1 (en) 2003-08-14 2004-08-13 2-substituted benzoic acid derivatives as hm74a receptor agonists

Publications (2)

Publication Number Publication Date
JP2007502264A JP2007502264A (ja) 2007-02-08
JP2007502264A5 true JP2007502264A5 (enExample) 2007-09-13

Family

ID=28052522

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006523062A Withdrawn JP2007502264A (ja) 2003-08-14 2004-08-13 Ｈｍ７４ａ受容体アゴニストとしての２−置換安息香酸誘導体

Country Status (4)

Country Link
EP (1) EP1670749A1 (enExample)
JP (1) JP2007502264A (enExample)
GB (1) GB0319124D0 (enExample)
WO (1) WO2005016870A1 (enExample)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094572B2 (en) 2003-03-14 2006-08-22 Bristol-Myers Squibb Polynucleotide encoding a novel human G-protein coupled receptor variant of HM74, HGPRBMY74
WO2005020921A2 (en) * 2003-08-29 2005-03-10 Exelixis, Inc. C-kit modulators and methods of use
TWI258478B (en) 2003-10-31 2006-07-21 Arena Pharm Inc Tetrazole derivatives and methods of treatment of metabolic-related disorders thereof
CA2587207A1 (en) * 2004-11-23 2006-06-01 Merck & Co., Inc. Niacin receptor agonists, compositions containing such compounds and methods of treatment
WO2006060461A1 (en) 2004-12-03 2006-06-08 Schering Corporation Substituted piperazines as cb1 antagonists
PE20060949A1 (es) 2004-12-23 2006-10-11 Arena Pharm Inc Derivados fusionados de pirazol como agonistas del receptor de niacina
GB0428526D0 (en) 2004-12-30 2005-02-09 Novartis Ag Organic compounds
EP1856053A1 (en) 2005-01-14 2007-11-21 Millennium Pharmaceuticals, Inc. Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity
GB0503054D0 (en) * 2005-02-14 2005-03-23 Smithkline Beecham Corp Chemical compounds
GB0503053D0 (en) * 2005-02-14 2005-03-23 Smithkline Beecham Corp Chemical compounds
GB0503056D0 (en) * 2005-02-14 2005-03-23 Smithkline Beecham Corp Chemical compounds
US20080221108A1 (en) * 2005-02-14 2008-09-11 Richard Hatley Anthranilic Acid Derivatives As Hm74A Receptor Agonists
AU2006236939A1 (en) * 2005-04-13 2006-10-26 Merck Sharp & Dohme Corp. Niacin receptor agonists, compositions containing such compounds and methods of treatment
KR100955112B1 (ko) 2005-06-14 2010-04-28 에프. 호프만-라 로슈 아게 안트라닐산 유도체
DK1901731T3 (da) 2005-06-28 2011-06-14 Merck Sharp & Dohme Niacinreceptoragonister, sammensætninger indeholdende sådanne forbindelser og fremgangsmåder til behandling
GB0516462D0 (en) * 2005-08-10 2005-09-14 Smithkline Beecham Corp Novel compounds
JP5112316B2 (ja) * 2005-08-10 2013-01-09 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 選択的ｈｍ７４ａアゴニストとしてのキサンチン誘導体
GB0516464D0 (en) * 2005-08-10 2005-09-14 Smithkline Beecham Corp Novel compounds
JP2009507791A (ja) * 2005-08-29 2009-02-26 メルク エンド カムパニー インコーポレーテッド ナイアシン受容体アゴニスト、このような化合物を含有する組成物、および治療方法
CA2622960A1 (en) * 2005-09-20 2007-03-29 Merck & Co., Inc. Niacin receptor agonists, compositions containing such compounds and methods of treatment
US20090042926A1 (en) * 2005-12-20 2009-02-12 Jason Imbriglio Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment
US8633160B2 (en) 2005-12-30 2014-01-21 Nono Inc. Small molecule inhibitors of PDZ interactions
KR101384572B1 (ko) * 2005-12-30 2014-04-24 아버 비타 코포레이션 Ｐｄｚ 상호작용의 소형 분자 억제제
WO2007092364A2 (en) * 2006-02-07 2007-08-16 Merck & Co., Inc. Niacin receptor agonists, compositions containing such compounds and methods of treatment
JP2009533436A (ja) * 2006-04-11 2009-09-17 メルク エンド カムパニー インコーポレーテッド ナイアシン受容体アゴニスト、かかる化合物を含有する組成物、及び治療法
US8071625B2 (en) 2006-08-02 2011-12-06 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
WO2008016676A2 (en) * 2006-08-02 2008-02-07 Cytokinetics, Incorporated Certain chemical entities, compositions, and methods
US8063082B2 (en) * 2006-08-02 2011-11-22 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
KR100832750B1 (ko) 2006-12-08 2008-05-27 한국화학연구원 Ｎ-페닐아마이드 유도체를 함유하는 허혈성 질환의 예방또는 치료용 조성물
WO2008069611A1 (en) * 2006-12-08 2008-06-12 Korea Research Institute Of Chemical Technology N-phenylamide derivative, process for the preparation thereof, and composition for preventing or treating ischemic diseases comprising same
US8309534B2 (en) 2007-05-15 2012-11-13 Medical College Of Georgia Research Institute, Inc. Compositions comprising a GPR109 ligand for treating disorders of the digestive tract and/or cancer
KR20100044251A (ko) 2007-08-15 2010-04-29 싸이토키네틱스, 인코포레이티드 특정 화학 물질, 조성물 및 방법
JP5627453B2 (ja) 2008-03-31 2014-11-19 株式会社レナサイエンス プラスミノーゲンアクチベーターインヒビター−１阻害剤
US8785473B2 (en) * 2009-03-31 2014-07-22 Renascience Co., Ltd. Plasminogen activator inhibitor-1 inhibitor
US8664425B2 (en) * 2010-02-02 2014-03-04 Honeywell International Inc. Bluegreen fluorescent compounds
US9527805B2 (en) * 2010-09-10 2016-12-27 Robert A. Casero Small molecules as epigenetic modulators of lysine-specific demethylase 1 and methods of treating disorders
WO2013092786A1 (en) * 2011-12-23 2013-06-27 Norgine B.V. Compositions comprising cetilistat
US10092537B2 (en) 2013-04-15 2018-10-09 Renascience Co., Ltd. Use for PAI-1 inhibitor
CN104418764B (zh) * 2013-09-11 2017-02-01 上海伊明化学科技有限公司 一种二氢燕麦酰基邻氨基苯甲酸d合成方法
ES2578377B1 (es) * 2014-12-22 2017-05-04 Consejo Superior De Investigaciones Científicas (Csic) Compuestos moduladores del sensor neuronal de calcio dream y sus usos terapéuticos.
CN106511110B (zh) * 2016-10-25 2019-10-01 福州美乐莲生物科技有限公司 二氢燕麦生物碱d盐类化合物作为化妆品活性成分的应用及其合成方法
EP3668843A1 (en) 2017-08-15 2020-06-24 Inflazome Limited Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
TW201910317A (zh) 2017-08-15 2019-03-16 愛爾蘭商英弗雷佐姆有限公司 新穎化合物
TW201910316A (zh) 2017-08-15 2019-03-16 愛爾蘭商英弗雷佐姆有限公司 新穎化合物
EP3707137A1 (en) 2017-11-09 2020-09-16 Inflazome Limited Novel sulfonamide carboxamide compounds
PE20210050A1 (es) 2017-11-09 2021-01-08 Inflazome Ltd Nuevos compuestos de sulfonamida carboxamida
WO2019166619A1 (en) 2018-03-02 2019-09-06 Inflazome Limited Novel compounds
EP3662908A1 (en) * 2018-12-04 2020-06-10 Consejo Superior de Investigaciones Cientificas (CSIC) Modulating compounds of kchip2 and its use for the treatment of cardiovascular pathologies
CN109553550B (zh) * 2018-12-29 2022-02-22 上海克琴科技有限公司 一种合成二氢燕麦生物碱的方法
CN112939803B (zh) * 2021-02-07 2023-07-18 郑州轻工业大学 一种二氢燕麦生物碱d的制备工艺
CN114478296B (zh) * 2022-02-14 2024-07-19 河南旭瑞新材料科技有限公司 一种二氢燕麦生物碱的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2934543A1 (de) * 1979-08-27 1981-04-02 Basf Ag, 6700 Ludwigshafen Substituierte n-benzoylanthranilsaeurederivate und deren anydroverbindungen, verfahren zu ihrer herstellung und ihre verwendung als herbizide
JPS59122449A (ja) * 1982-12-28 1984-07-14 Kissei Pharmaceut Co Ltd 芳香族カルボン酸アミド誘導体の製造方法
JPS6097946A (ja) * 1983-11-01 1985-05-31 Ono Pharmaceut Co Ltd カルボキサミド誘導体
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
US5808144A (en) * 1995-11-27 1998-09-15 Teijin Limited Benzene derivatives
FR2763334A1 (fr) * 1997-05-13 1998-11-20 Lipha Derives anthraniliques
BR9811828A (pt) * 1997-08-05 2000-08-15 American Home Prod Análogos do ácido antranìlico
BR9811845A (pt) * 1997-08-05 2000-08-08 American Home Prod Análogos do ácido antranìlico
US6649656B1 (en) * 1998-07-24 2003-11-18 Teijin Limited Anthranilic acid derivatives
DE69926148D1 (en) * 1998-11-09 2005-08-18 Black James Foundation Gastrin und cholecystokinin rezeptor ligande
AR022204A1 (es) * 1999-01-08 2002-09-04 Norgine Bv Compuesto, proceso para su preparacion, composicion farmaceutica y producto comestible que lo comprende.
AU2001234089B2 (en) * 2000-02-15 2005-08-11 Teijin Limited Cancer remedy comprising anthranilic acid derivative as active ingredient
DE10133665A1 (de) * 2001-07-11 2003-01-30 Boehringer Ingelheim Pharma Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung

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