JP2021523933A5 - - Google Patents

Info

Publication number
JP2021523933A5
JP2021523933A5 JP2021506390A JP2021506390A JP2021523933A5 JP 2021523933 A5 JP2021523933 A5 JP 2021523933A5 JP 2021506390 A JP2021506390 A JP 2021506390A JP 2021506390 A JP2021506390 A JP 2021506390A JP 2021523933 A5 JP2021523933 A5 JP 2021523933A5
Authority
JP
Japan
Prior art keywords
trifluoromethyl
pyrazine
imidazo
phenyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021506390A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021523933A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/028555 external-priority patent/WO2019204816A1/en
Publication of JP2021523933A publication Critical patent/JP2021523933A/ja
Publication of JP2021523933A5 publication Critical patent/JP2021523933A5/ja
Pending legal-status Critical Current

Links

JP2021506390A 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なイミダゾピリジン Pending JP2021523933A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862660880P 2018-04-20 2018-04-20
US62/660,880 2018-04-20
PCT/US2019/028555 WO2019204816A1 (en) 2018-04-20 2019-04-22 Imidazopyridines useful as mitochondrial uncouplers

Publications (2)

Publication Number Publication Date
JP2021523933A JP2021523933A (ja) 2021-09-09
JP2021523933A5 true JP2021523933A5 (enExample) 2022-04-26

Family

ID=67139787

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2021506390A Pending JP2021523933A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なイミダゾピリジン
JP2021506391A Pending JP2021523934A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なアミノピラジンおよび関連化合物
JP2021506388A Pending JP2021522327A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なオキサジアゾロピラジンおよびオキサジアゾロピリジン

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021506391A Pending JP2021523934A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なアミノピラジンおよび関連化合物
JP2021506388A Pending JP2021522327A (ja) 2018-04-20 2019-04-22 ミトコンドリア脱共役剤として有用なオキサジアゾロピラジンおよびオキサジアゾロピリジン

Country Status (12)

Country Link
US (3) US11708376B2 (enExample)
EP (3) EP3781567B1 (enExample)
JP (3) JP2021523933A (enExample)
KR (3) KR20210003831A (enExample)
CN (3) CN112262146A (enExample)
AU (2) AU2019256722A1 (enExample)
BR (2) BR112020021469A2 (enExample)
CA (2) CA3097752A1 (enExample)
IL (2) IL278070A (enExample)
MX (2) MX2020011050A (enExample)
WO (3) WO2019204819A1 (enExample)
ZA (2) ZA202006296B (enExample)

Families Citing this family (5)

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KR20210003831A (ko) * 2018-04-20 2021-01-12 버지니아 테크 인터렉추얼 프라퍼티스, 인크. 미토콘드리아 언커플러로서 유용한 아미노피라진 및 관련 화합물
WO2020191503A1 (en) * 2019-03-27 2020-10-01 Algernon Pharmaceuticals Inc. Methods and uses of bromantane and derivatives thereof for treating lung disease, fatty liver disease, and kidney disorders
WO2022013684A1 (en) 2020-07-11 2022-01-20 Pfizer Inc. Antiviral heteroaryl ketone derivatives
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds
US20250170127A1 (en) * 2022-02-21 2025-05-29 The Regents Of The University Of Colorado, A Body Corporate Re-sensitizing multidrug-resistant (mdr) gram-negative bacteria to colistin using ionophores

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US11896591B2 (en) * 2017-05-22 2024-02-13 University Of Virginia Patent Foundation Compositions and methods for preparing and using mitochondrial uncouplers
KR20210003831A (ko) * 2018-04-20 2021-01-12 버지니아 테크 인터렉추얼 프라퍼티스, 인크. 미토콘드리아 언커플러로서 유용한 아미노피라진 및 관련 화합물

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