JP2002529532A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002529532A5 JP2002529532A5 JP2000582365A JP2000582365A JP2002529532A5 JP 2002529532 A5 JP2002529532 A5 JP 2002529532A5 JP 2000582365 A JP2000582365 A JP 2000582365A JP 2000582365 A JP2000582365 A JP 2000582365A JP 2002529532 A5 JP2002529532 A5 JP 2002529532A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkyl
- methyl
- nitro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 description 18
- -1 nitro, hydroxyl Chemical group 0.000 description 10
- 125000001424 substituent group Chemical group 0.000 description 10
- 229910052739 hydrogen Inorganic materials 0.000 description 7
- 239000001257 hydrogen Substances 0.000 description 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 4
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 description 3
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 description 3
- 125000000217 alkyl group Chemical group 0.000 description 3
- 230000000507 anthelmentic effect Effects 0.000 description 3
- 125000004093 cyano group Chemical group *C#N 0.000 description 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 3
- 229910052736 halogen Inorganic materials 0.000 description 3
- 125000005843 halogen group Chemical group 0.000 description 3
- 150000002367 halogens Chemical group 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 244000045947 parasite Species 0.000 description 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 2
- 125000003358 C2-C20 alkenyl group Chemical group 0.000 description 2
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 2
- 229910052794 bromium Inorganic materials 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 229910052731 fluorine Inorganic materials 0.000 description 2
- 239000011737 fluorine Substances 0.000 description 2
- 125000004438 haloalkoxy group Chemical group 0.000 description 2
- 125000000623 heterocyclic group Chemical group 0.000 description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
- 229910052740 iodine Inorganic materials 0.000 description 2
- 239000011630 iodine Substances 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 description 1
- VUAXHMVRKOTJKP-UHFFFAOYSA-N 2,2-dimethylbutyric acid Chemical compound CCC(C)(C)C(O)=O VUAXHMVRKOTJKP-UHFFFAOYSA-N 0.000 description 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- MNWFXJYAOYHMED-UHFFFAOYSA-N hexane carboxylic acid Natural products CCCCCCC(O)=O MNWFXJYAOYHMED-UHFFFAOYSA-N 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 239000004540 pour-on Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000004544 spot-on Substances 0.000 description 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH2298/98 | 1998-11-17 | ||
| CH229898 | 1998-11-17 | ||
| CH797/99 | 1999-04-29 | ||
| CH79799 | 1999-04-29 | ||
| PCT/EP1999/008765 WO2000029378A2 (en) | 1998-11-17 | 1999-11-15 | Acyclic and cyclic guanidine- and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002529532A JP2002529532A (ja) | 2002-09-10 |
| JP2002529532A5 true JP2002529532A5 (enExample) | 2007-01-25 |
Family
ID=25685711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000582365A Withdrawn JP2002529532A (ja) | 1998-11-17 | 1999-11-15 | 非環状および環状グアニジンおよびアセトアミジン誘導体、それらの製造ならびに農薬特に駆虫薬としての使用 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6538013B2 (enExample) |
| EP (1) | EP1131292B1 (enExample) |
| JP (1) | JP2002529532A (enExample) |
| KR (1) | KR100620470B1 (enExample) |
| CN (1) | CN1177823C (enExample) |
| AR (1) | AR023703A1 (enExample) |
| AT (1) | ATE317385T1 (enExample) |
| AU (1) | AU762529B2 (enExample) |
| BR (1) | BR9915430A (enExample) |
| CA (1) | CA2350742A1 (enExample) |
| CO (1) | CO5210925A1 (enExample) |
| CY (1) | CY1106083T1 (enExample) |
| DE (1) | DE69929820T2 (enExample) |
| DK (1) | DK1131292T3 (enExample) |
| ES (1) | ES2255766T3 (enExample) |
| HK (1) | HK1038563B (enExample) |
| IL (2) | IL142687A0 (enExample) |
| NZ (1) | NZ511380A (enExample) |
| PT (1) | PT1131292E (enExample) |
| RU (1) | RU2245877C2 (enExample) |
| TW (1) | TW561149B (enExample) |
| WO (1) | WO2000029378A2 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| US6933318B1 (en) | 1999-08-12 | 2005-08-23 | Eli Lilly And Company | Topical organic ectoparasiticidal formulations |
| EP1207851A1 (en) * | 1999-08-12 | 2002-05-29 | Eli Lilly And Company | Topical organic ectoparasiticidal formulations |
| US6376548B1 (en) | 2000-01-28 | 2002-04-23 | Rohm And Haas Company | Enhanced propertied pesticides |
| US7186855B2 (en) * | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7232924B2 (en) | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
| PT1404324E (pt) * | 2001-06-11 | 2008-03-05 | Xenoport Inc | Formas de dosagem administradas oralmente de pró-fármacos análogas de gaba tendo toxicidade reduzida |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| JP2003026603A (ja) * | 2001-07-17 | 2003-01-29 | Sumika Life Tech Co Ltd | コンパニオンアニマルの外部寄生虫駆除用水性滴下剤 |
| US7011837B2 (en) * | 2001-08-29 | 2006-03-14 | Rutgers, The State University Of New Jersey | Isolated species of steinernematid nematode and methods of white grub control therewith |
| EP2347654B1 (en) | 2001-09-17 | 2019-02-27 | Elanco US Inc. | Formulation for controlling lice or ticks in catlle |
| CN101597262A (zh) * | 2002-03-05 | 2009-12-09 | 特兰斯泰克制药公司 | 抑制配体与高级糖化终产物受体相互作用的单和双环吡咯衍生物 |
| MXPA05012350A (es) * | 2003-05-20 | 2006-05-25 | Transtech Pharma Inc | Antagonistas rage como agentes para la amiloidosis inversa y enfermedades asociadas con la misma. |
| US7396819B2 (en) * | 2003-08-08 | 2008-07-08 | Virbac Corporation | Anthelmintic formulations |
| US7531186B2 (en) * | 2003-12-17 | 2009-05-12 | Merial Limited | Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz |
| WO2005094210A2 (en) * | 2004-03-12 | 2005-10-13 | The Hartz Mountain Corporation | Multi-action anthelmintic formulations |
| GT200500317A (es) * | 2004-11-05 | 2006-10-27 | Proceso para preparar compuestos de quinolina y productos obtenidos de los mismos | |
| AR054849A1 (es) * | 2005-07-26 | 2007-07-18 | Wyeth Corp | Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas |
| JP5053289B2 (ja) * | 2005-12-22 | 2012-10-17 | エフ エム シー コーポレーション | ビフェントリンおよび強力シペルメトリンの新規な処方物 |
| TW200734334A (en) * | 2006-01-13 | 2007-09-16 | Wyeth Corp | Treatment of substance abuse |
| KR20080110759A (ko) * | 2006-03-24 | 2008-12-19 | 와이어쓰 | 통증 치료 |
| PE20080125A1 (es) * | 2006-03-24 | 2008-04-07 | Wyeth Corp | Metodo para modular la funcion de la vejiga |
| TW200806300A (en) * | 2006-03-24 | 2008-02-01 | Wyeth Corp | New therapeutic combinations for the treatment of depression |
| US20070225278A1 (en) * | 2006-03-24 | 2007-09-27 | Wyeth | Methods for treating cognitive and other disorders |
| RU2340181C1 (ru) * | 2007-03-06 | 2008-12-10 | Александр Анатольевич Хахалин | Инсектоакарицидное средство "инсектал-плюс" |
| CL2008002777A1 (es) * | 2007-09-21 | 2010-01-22 | Wyeth Corp | Metodo de preparacion de compuestos diazepinoquinolinicos quirales por recristalizacion en un sistema de solvente ternario. |
| FR2922108A1 (fr) | 2007-10-11 | 2009-04-17 | Virbac Sa | Utilisation d'un derive de 1-n-(halo-3-pyridylmethyle)-n-methylamino-1-alkylamino -2- nitroethylene pour la preparation d'une composition pharmaceutique veterinaire pour lutter contre les puces |
| CN101854928A (zh) * | 2007-11-08 | 2010-10-06 | 希普洛有限公司 | 包含燕麦蒽酰胺的组合物 |
| US9173728B2 (en) | 2008-11-19 | 2015-11-03 | Merial Inc. | Multi-cavity container having offset indentures for dispensing fluids |
| CN102271672B (zh) | 2008-11-19 | 2015-02-04 | 梅里亚有限公司 | 用于治疗寄生物感染的包含单独的或与甲脒组合的1-芳基吡唑的组合物 |
| EP2470510B1 (en) | 2009-09-30 | 2014-05-14 | TransTech Pharma, LLC | Substituted imidazole derivatives for treatment of alzheimers disease. |
| UA115967C2 (uk) | 2011-01-04 | 2018-01-25 | Зе Клаймат Корпорейшн | Способи генерування карт ґрунтів і приписів щодо посіву насіння |
| WO2012138320A1 (en) * | 2011-04-04 | 2012-10-11 | Carro, A | Ingestible insect repellent composition and system |
| NZ722096A (en) | 2011-12-15 | 2016-11-25 | Alkermes Pharma Ireland Ltd | Prodrugs of secondary amine compounds |
| US10743535B2 (en) | 2017-08-18 | 2020-08-18 | H&K Solutions Llc | Insecticide for flight-capable pests |
| CN111978243B (zh) * | 2019-05-24 | 2022-09-06 | 南开大学 | 草酸单酯类衍生物的合成及其应用 |
| CN111978244B (zh) * | 2019-05-24 | 2022-09-06 | 南开大学 | 一类烯啶虫胺酰基衍生物的合成及其应用 |
| US11895941B2 (en) | 2019-09-23 | 2024-02-13 | Cnh Industrial America Llc | Tillage system with variable fertilizer application |
| TWI893037B (zh) * | 2019-12-23 | 2025-08-11 | 美商欣爍克斯公司 | 製備n6-((2-疊氮基乙氧基)羰基)離胺酸的方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZW5085A1 (en) | 1984-04-13 | 1985-09-18 | Nihon Tokushu Noyaku Seizo Kk | Nitromethylene derivatives,intermediates thereof,processes for production thereof,and insecticides |
| ATE67493T1 (de) * | 1985-02-04 | 1991-10-15 | Bayer Agrochem Kk | Heterocyclische verbindungen. |
| JPH07121909B2 (ja) | 1986-09-10 | 1995-12-25 | 日本バイエルアグロケム株式会社 | 新規複素環式化合物及び殺虫剤 |
| DE3712307A1 (de) | 1987-04-10 | 1988-10-20 | Bayer Ag | 3-substituierte 1-(2-chlor-thiazol-5-yl-methyl)-2- nitroimino-1,3-diazacycloalkane |
| ATE166051T1 (de) | 1987-08-01 | 1998-05-15 | Takeda Chemical Industries Ltd | Zwischenprodukte, ihre herstellung und verwendung zur herstellung alpha-ungesättigter amine |
| DE3887800D1 (de) | 1987-08-04 | 1994-03-24 | Ciba Geigy | Substituierte Guanidine. |
| US4918086A (en) | 1987-08-07 | 1990-04-17 | Ciba-Geigy Corporation | 1-nitro-2,2-diaminoethylene derivatives |
| JP2884412B2 (ja) | 1988-10-21 | 1999-04-19 | 日本バイエルアグロケム株式会社 | 殺虫性シアノ化合物 |
| JP2779403B2 (ja) | 1988-11-29 | 1998-07-23 | 日本バイエルアグロケム株式会社 | 殺虫性ニトロ化合物 |
| IE71183B1 (en) | 1988-12-27 | 1997-01-29 | Takeda Chemical Industries Ltd | Guanidine derivatives their production and insecticides |
| IL93159A (en) | 1989-01-31 | 1996-11-14 | Takeda Chemical Industries Ltd | Process for the production of 1,1,1-trihalogen-2-nitroethanes |
| GB2228003A (en) | 1989-02-13 | 1990-08-15 | Shell Int Research | Pesticidal nitroethene compounds |
| ES2059841T3 (es) | 1989-02-13 | 1994-11-16 | Bayer Agrochem Kk | Nitro compuestos con actividad insecticida. |
| JP2610988B2 (ja) | 1989-03-09 | 1997-05-14 | 日本バイエルアグロケム 株式会社 | 新規ヘテロ環式化合物及び殺虫剤 |
| IL99161A (en) * | 1990-08-17 | 1996-11-14 | Takeda Chemical Industries Ltd | History of guanidine A process for their preparation and preparations from pesticides that contain them |
| IL99445A (en) | 1990-09-18 | 1996-06-18 | Ciba Geigy Ag | Picoline oxides process for their preparation and insecticidal and acaricidal compositions containing them |
| DE4207604A1 (de) | 1991-03-13 | 1992-09-17 | Ciba Geigy Ag | Schaedlingsbekaempfungsmittel |
| JPH05112521A (ja) * | 1991-03-22 | 1993-05-07 | Takeda Chem Ind Ltd | ニトログアニジン誘導体の製造方法、その中間体及びその製造方法 |
| JPH0511251A (ja) | 1991-07-01 | 1993-01-19 | Canon Inc | 高分子液晶の配向方法および高分子液晶素子 |
| JP2783912B2 (ja) | 1992-05-23 | 1998-08-06 | ノバルティス アクチェンゲゼルシャフト | 家畜内の蚤を駆除するための１−〔ｎ−（ハロ−３−ピリジルメチル）〕−ｎ−メチルアミノ−１−アルキルアミノ−２−ニトロエチレン誘導体 |
| DE4232561A1 (de) | 1992-09-29 | 1994-03-31 | Bayer Ag | Bekämpfung von Fischparasiten |
| AU4297197A (en) * | 1996-08-08 | 1998-03-06 | Novartis Ag | Substituted 4-nitroimino-perhydro-1,3,5-oxadiazine derivatives, their use as pesticides and intermediates for their preparation |
-
1999
- 1999-11-12 CO CO99071586A patent/CO5210925A1/es not_active Application Discontinuation
- 1999-11-15 NZ NZ511380A patent/NZ511380A/en unknown
- 1999-11-15 TW TW088119841A patent/TW561149B/zh not_active IP Right Cessation
- 1999-11-15 IL IL14268799A patent/IL142687A0/xx active IP Right Grant
- 1999-11-15 AU AU15531/00A patent/AU762529B2/en not_active Ceased
- 1999-11-15 EP EP99958038A patent/EP1131292B1/en not_active Expired - Lifetime
- 1999-11-15 RU RU2001116594/04A patent/RU2245877C2/ru not_active IP Right Cessation
- 1999-11-15 BR BR9915430-7A patent/BR9915430A/pt not_active Application Discontinuation
- 1999-11-15 WO PCT/EP1999/008765 patent/WO2000029378A2/en not_active Ceased
- 1999-11-15 ES ES99958038T patent/ES2255766T3/es not_active Expired - Lifetime
- 1999-11-15 KR KR1020017006159A patent/KR100620470B1/ko not_active Expired - Fee Related
- 1999-11-15 AR ARP990105795A patent/AR023703A1/es unknown
- 1999-11-15 DK DK99958038T patent/DK1131292T3/da active
- 1999-11-15 HK HK02100209.5A patent/HK1038563B/en not_active IP Right Cessation
- 1999-11-15 JP JP2000582365A patent/JP2002529532A/ja not_active Withdrawn
- 1999-11-15 PT PT99958038T patent/PT1131292E/pt unknown
- 1999-11-15 DE DE69929820T patent/DE69929820T2/de not_active Expired - Fee Related
- 1999-11-15 CA CA002350742A patent/CA2350742A1/en not_active Abandoned
- 1999-11-15 CN CNB998133175A patent/CN1177823C/zh not_active Expired - Fee Related
- 1999-11-15 AT AT99958038T patent/ATE317385T1/de not_active IP Right Cessation
-
2001
- 2001-04-19 IL IL142687A patent/IL142687A/en not_active IP Right Cessation
- 2001-05-07 US US09/850,378 patent/US6538013B2/en not_active Expired - Fee Related
-
2003
- 2003-01-21 US US10/348,574 patent/US6759407B2/en not_active Expired - Fee Related
-
2004
- 2004-02-17 US US10/779,932 patent/US7271184B2/en not_active Expired - Fee Related
-
2006
- 2006-05-04 CY CY20061100580T patent/CY1106083T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002529532A5 (enExample) | ||
| JP5702392B2 (ja) | キサンチンオキシダーゼ阻害剤として効果的な新規化合物、その製造方法及びそれを含有する医薬組成物 | |
| RU2342383C2 (ru) | ПРОИЗВОДНЫЕ ИМИДАЗОЛ-4-ИЛЭТИНИЛПИРИДИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ (ВАРИАНТЫ) И ПРИМЕНЕНИЕ В КАЧЕСТВЕ АНКСИОЛИТИКА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ НАРУШЕНИЙ, ОПОСРЕДУЕМЫХ РЕЦЕПТОРОМ mGLuR5 | |
| JP2007507542A5 (enExample) | ||
| JP2008511683A5 (enExample) | ||
| JP2005527625A5 (enExample) | ||
| JP2017504576A5 (enExample) | ||
| ZA200508158B (en) | Derivatives of piperidinyl- and piperazinyl-alkyl carbamates, preparation methods thereof and application of same in therapeutics | |
| CA2565813A1 (en) | Substituted methyl aryl or heteroaryl amide compounds | |
| JP2009519965A5 (enExample) | ||
| JP2003128673A5 (enExample) | ||
| JP2012522763A5 (enExample) | ||
| CA2486399A1 (en) | Calcium receptor modulating agents | |
| JP2007517035A5 (enExample) | ||
| JP2004534096A5 (enExample) | ||
| JP2007512349A5 (enExample) | ||
| RU2001116594A (ru) | Пестициды | |
| RU97119064A (ru) | Применение альфа(il)-агонистов для лечения недержания мочи | |
| CA2485926A1 (en) | (imidazol-1-yl-methyl)-pyridazine as nmda receptor blocker | |
| CA2683059A1 (en) | Atropisomer of pyrrole derivative | |
| CA2602738A1 (en) | Aminopyrimidine compounds and their salts, process for preparation and pharmaceutical use thereof | |
| JP2004525183A5 (enExample) | ||
| JP2006508192A5 (enExample) | ||
| JP2006507355A5 (enExample) | ||
| RU2007108863A (ru) | Производные пиразола для лечения состояний, опосредованных активацией рецептора аденозина а2в или а3 |