JP2017504576A5 - - Google Patents
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- Publication number
- JP2017504576A5 JP2017504576A5 JP2016536162A JP2016536162A JP2017504576A5 JP 2017504576 A5 JP2017504576 A5 JP 2017504576A5 JP 2016536162 A JP2016536162 A JP 2016536162A JP 2016536162 A JP2016536162 A JP 2016536162A JP 2017504576 A5 JP2017504576 A5 JP 2017504576A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- acetamide
- hydroxypropan
- hexafluoro
- cyclopropylmethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13195813 | 2013-12-05 | ||
| EP13195813.4 | 2013-12-05 | ||
| EP14183274 | 2014-09-02 | ||
| EP14183274.1 | 2014-09-02 | ||
| PCT/EP2014/076390 WO2015082533A1 (en) | 2013-12-05 | 2014-12-03 | Ror gamma (rory) modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017504576A JP2017504576A (ja) | 2017-02-09 |
| JP2017504576A5 true JP2017504576A5 (enExample) | 2018-12-27 |
| JP6461960B2 JP6461960B2 (ja) | 2019-01-30 |
Family
ID=52021176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016536162A Expired - Fee Related JP6461960B2 (ja) | 2013-12-05 | 2014-12-03 | ＲＯＲガンマ（γ）モジュレータ |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9738600B2 (enExample) |
| EP (1) | EP3077372B8 (enExample) |
| JP (1) | JP6461960B2 (enExample) |
| KR (1) | KR102251128B1 (enExample) |
| CN (1) | CN105980353B (enExample) |
| AU (1) | AU2014359324B2 (enExample) |
| CA (1) | CA2932483C (enExample) |
| CL (1) | CL2016001364A1 (enExample) |
| CR (1) | CR20160303A (enExample) |
| DK (1) | DK3077372T3 (enExample) |
| DO (1) | DOP2016000125A (enExample) |
| EA (1) | EA030393B1 (enExample) |
| ES (1) | ES2722409T3 (enExample) |
| HR (1) | HRP20190483T1 (enExample) |
| HU (1) | HUE043258T2 (enExample) |
| IL (1) | IL246018B (enExample) |
| LT (1) | LT3077372T (enExample) |
| MX (1) | MX368721B (enExample) |
| MY (1) | MY179106A (enExample) |
| PE (1) | PE20160891A1 (enExample) |
| PH (1) | PH12016501066A1 (enExample) |
| PL (1) | PL3077372T3 (enExample) |
| PT (1) | PT3077372T (enExample) |
| RS (1) | RS58650B1 (enExample) |
| SI (1) | SI3077372T1 (enExample) |
| TN (1) | TN2016000224A1 (enExample) |
| UA (1) | UA117941C2 (enExample) |
| WO (1) | WO2015082533A1 (enExample) |
| ZA (1) | ZA201604043B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2942871A1 (en) * | 2014-03-27 | 2015-10-01 | Piramal Enterprises Limited | Ror-gamma modulators and uses thereof |
| CA2940264A1 (en) * | 2014-04-16 | 2015-10-22 | Glenmark Pharmaceuticals S.A. | Aryl and heteroaryl ether compounds as ror gamma modulators |
| TWI705057B (zh) | 2014-10-30 | 2020-09-21 | 比利時商健生藥品公司 | 用作ＲＯＲγｔ調節劑之三氟甲基醇 |
| US9861618B2 (en) | 2014-10-30 | 2018-01-09 | Janssen Pharmaceutica Nv | Thiazoles as modulators of RORγt |
| WO2016069978A1 (en) | 2014-10-30 | 2016-05-06 | Janssen Pharmaceutica Nv | AMIDE SUBSTITUTED THIAZOLES AS MODULATORS OF RORγT |
| CN107614062A (zh) | 2015-03-12 | 2018-01-19 | 加利福尼亚大学董事会 | 用RORγ抑制剂治疗癌症的方法 |
| KR102702236B1 (ko) | 2015-05-15 | 2024-09-04 | 오리진 온콜로지 리미티드 | Ror 감마 조절제로서의 치환된 테트라하이드로퀴놀리논 화합물 |
| WO2016193894A1 (en) * | 2015-05-29 | 2016-12-08 | Glenmark Pharmaceuticals S.A. | Treatment of respiratory disorders using ror- gamma inhibitors |
| EP3101008A1 (en) * | 2015-06-05 | 2016-12-07 | Lead Pharma Cel Models IP B.V. | Ror gamma (rory) modulators |
| EP3101005A1 (en) * | 2015-06-05 | 2016-12-07 | Lead Pharma Cel Models IP B.V. | Ror gamma (rory) modulators |
| WO2017010399A1 (ja) * | 2015-07-10 | 2017-01-19 | 塩野義製薬株式会社 | ＲＯＲγｔ阻害作用を有する化合物およびそれらを含有する医薬組成物 |
| KR101947976B1 (ko) | 2015-12-15 | 2019-02-13 | 아스트라제네카 아베 | 이소인돌 화합물 |
| TW201803869A (zh) | 2016-04-27 | 2018-02-01 | 健生藥品公司 | 作為ＲＯＲγＴ調節劑之６－胺基吡啶－３－基噻唑 |
| WO2018011747A1 (en) * | 2016-07-14 | 2018-01-18 | Cadila Healthcare Limited | Polycyclic compounds as ror-gamma modulators |
| TW201811760A (zh) | 2016-07-14 | 2018-04-01 | 印度商卡迪拉保健有限公司 | 新穎的環丙基衍生物 |
| AR110481A1 (es) | 2016-12-05 | 2019-04-03 | Lead Pharma Holding Bv | MODULADORES DE ROR g (RORg) |
| WO2018116285A1 (en) * | 2016-12-23 | 2018-06-28 | Glenmark Pharmaceuticals S.A. | Substituted morpholine derivatives as ror gamma modulators |
| EP3638661A1 (en) | 2017-06-14 | 2020-04-22 | Astrazeneca AB | 2,3-dihydroisoindole-1-carboxamides useful as ror-gamma modulators |
| CN112566901A (zh) | 2018-06-18 | 2021-03-26 | 詹森药业有限公司 | 作为RORγt的调节剂的苯基取代的吡唑类 |
| US10975057B2 (en) | 2018-06-18 | 2021-04-13 | Janssen Pharmaceutica Nv | 6-aminopyridin-3-yl pyrazoles as modulators of RORgT |
| US11034658B2 (en) | 2018-06-18 | 2021-06-15 | Janssen Pharmaceutica Nv | Pyridinyl pyrazoles as modulators of RORγT |
| CN112334450A (zh) | 2018-06-18 | 2021-02-05 | 詹森药业有限公司 | 作为RORγt的调节剂的苯基和吡啶基取代的咪唑 |
| CN113874080B (zh) | 2019-02-06 | 2024-09-27 | 戴斯阿尔法公司 | Il-17a调节剂及其用途 |
| JP7566889B2 (ja) * | 2019-09-16 | 2024-10-15 | ダイス・アルファ・インコーポレイテッド | Ｉｌ－１７ａモジュレーターおよびその使用 |
| CN112759541B (zh) * | 2019-10-21 | 2023-03-17 | 复旦大学 | 类吲哚衍生物及其用途 |
| TW202136238A (zh) * | 2020-01-06 | 2021-10-01 | 大陸商廣東東陽光藥業有限公司 | RORγt抑制劑及其製備方法和用途 |
| CN113072521B (zh) * | 2020-01-06 | 2024-04-05 | 广东东阳光药业股份有限公司 | RORγt抑制剂及其在药物中的应用 |
| CN114075139B (zh) * | 2020-08-14 | 2025-09-26 | 广东东阳光药业股份有限公司 | 五元杂芳环类化合物及其在药物中的应用 |
| CN120383557A (zh) * | 2024-01-26 | 2025-07-29 | 上海医药集团股份有限公司 | 一种乙磺酰苯基乙酰胺类化合物的晶型、其制备方法及应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011115892A1 (en) * | 2010-03-15 | 2011-09-22 | Griffin Patrick R | Modulators of the retinoic acid receptor-related orphan receptors |
| WO2012027965A1 (en) * | 2010-09-01 | 2012-03-08 | Glaxo Group Limited | Novel compounds |
| WO2013029338A1 (en) * | 2011-09-01 | 2013-03-07 | Glaxo Group Limited | Novel compounds |
| WO2014062655A1 (en) * | 2012-10-16 | 2014-04-24 | Janssen Pharmaceutica Nv | HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt |
| WO2013171729A2 (en) | 2013-01-08 | 2013-11-21 | Glenmark Pharmaceuticals S.A. | Aryl and heteroaryl amide compounds as rorgamat modulator |
| CN105121404A (zh) * | 2013-03-15 | 2015-12-02 | 豪夫迈·罗氏有限公司 | 作为RORc调节剂的芳基磺酰胺和氨基磺酸衍生物 |
| EP2781217A1 (en) * | 2013-03-18 | 2014-09-24 | ETH Zurich | ROR gamma modulators |
-
2014
- 2014-12-03 WO PCT/EP2014/076390 patent/WO2015082533A1/en not_active Ceased
- 2014-12-03 PL PL14809794T patent/PL3077372T3/pl unknown
- 2014-12-03 EA EA201691173A patent/EA030393B1/ru not_active IP Right Cessation
- 2014-12-03 SI SI201431174T patent/SI3077372T1/sl unknown
- 2014-12-03 HR HRP20190483TT patent/HRP20190483T1/hr unknown
- 2014-12-03 ES ES14809794T patent/ES2722409T3/es active Active
- 2014-12-03 PT PT14809794T patent/PT3077372T/pt unknown
- 2014-12-03 EP EP14809794.2A patent/EP3077372B8/en active Active
- 2014-12-03 RS RS20190494A patent/RS58650B1/sr unknown
- 2014-12-03 CA CA2932483A patent/CA2932483C/en active Active
- 2014-12-03 DK DK14809794.2T patent/DK3077372T3/en active
- 2014-12-03 PE PE2016000733A patent/PE20160891A1/es unknown
- 2014-12-03 CR CR20160303A patent/CR20160303A/es unknown
- 2014-12-03 MY MYPI2016702008A patent/MY179106A/en unknown
- 2014-12-03 KR KR1020167017849A patent/KR102251128B1/ko not_active Expired - Fee Related
- 2014-12-03 LT LTEP14809794.2T patent/LT3077372T/lt unknown
- 2014-12-03 CN CN201480074695.6A patent/CN105980353B/zh not_active Expired - Fee Related
- 2014-12-03 JP JP2016536162A patent/JP6461960B2/ja not_active Expired - Fee Related
- 2014-12-03 MX MX2016007275A patent/MX368721B/es active IP Right Grant
- 2014-12-03 UA UAA201607189A patent/UA117941C2/uk unknown
- 2014-12-03 US US15/102,098 patent/US9738600B2/en not_active Expired - Fee Related
- 2014-12-03 AU AU2014359324A patent/AU2014359324B2/en not_active Ceased
- 2014-12-03 HU HUE14809794A patent/HUE043258T2/hu unknown
- 2014-12-03 TN TN2016000224A patent/TN2016000224A1/en unknown
-
2016
- 2016-06-03 CL CL2016001364A patent/CL2016001364A1/es unknown
- 2016-06-03 DO DO2016000125A patent/DOP2016000125A/es unknown
- 2016-06-03 PH PH12016501066A patent/PH12016501066A1/en unknown
- 2016-06-05 IL IL246018A patent/IL246018B/en active IP Right Grant
- 2016-06-14 ZA ZA2016/04043A patent/ZA201604043B/en unknown
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