JP2021500311A5 - - Google Patents
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- JP2021500311A5 JP2021500311A5 JP2020515190A JP2020515190A JP2021500311A5 JP 2021500311 A5 JP2021500311 A5 JP 2021500311A5 JP 2020515190 A JP2020515190 A JP 2020515190A JP 2020515190 A JP2020515190 A JP 2020515190A JP 2021500311 A5 JP2021500311 A5 JP 2021500311A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotides
- modification
- capping
- composition
- coupling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024063134A JP2024105256A (ja) | 2017-09-18 | 2024-04-10 | オリゴヌクレオチド調製のための技術 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762560169P | 2017-09-18 | 2017-09-18 | |
| US62/560,169 | 2017-09-18 | ||
| PCT/US2018/051398 WO2019055951A1 (en) | 2017-09-18 | 2018-09-17 | OLIGONUCLEOTIDE PREPARATION TECHNOLOGIES |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024063134A Division JP2024105256A (ja) | 2017-09-18 | 2024-04-10 | オリゴヌクレオチド調製のための技術 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021500311A JP2021500311A (ja) | 2021-01-07 |
| JP2021500311A5 true JP2021500311A5 (enExample) | 2021-11-25 |
| JP7472018B2 JP7472018B2 (ja) | 2024-04-22 |
Family
ID=65723422
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515190A Active JP7472018B2 (ja) | 2017-09-18 | 2018-09-17 | オリゴヌクレオチド調製のための技術 |
| JP2024063134A Pending JP2024105256A (ja) | 2017-09-18 | 2024-04-10 | オリゴヌクレオチド調製のための技術 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024063134A Pending JP2024105256A (ja) | 2017-09-18 | 2024-04-10 | オリゴヌクレオチド調製のための技術 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US11608355B2 (enExample) |
| EP (1) | EP3684755A4 (enExample) |
| JP (2) | JP7472018B2 (enExample) |
| KR (2) | KR20250123934A (enExample) |
| CN (1) | CN111108096A (enExample) |
| AU (2) | AU2018333065B2 (enExample) |
| CA (1) | CA3072110A1 (enExample) |
| SG (1) | SG11202000276YA (enExample) |
| WO (1) | WO2019055951A1 (enExample) |
Families Citing this family (48)
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| PL2872485T3 (pl) | 2012-07-13 | 2021-05-31 | Wave Life Sciences Ltd. | Asymetryczna grupa pomocnicza |
| KR102213609B1 (ko) | 2012-07-13 | 2021-02-08 | 웨이브 라이프 사이언시스 리미티드 | 키랄 제어 |
| BR112016016400A2 (pt) | 2014-01-16 | 2017-10-03 | Wave Life Sciences Ltd | Composições de oligonucleotídeos quiralmente controlados, seu uso, sua composição farmacêutica, e métodos |
| IL320434A (en) | 2015-07-22 | 2025-06-01 | Wave Life Sciences Ltd | Oligonucleotide preparations and methods |
| IL295755A (en) | 2015-10-09 | 2022-10-01 | Wave Life Sciences Ltd | Oligonucleotide compositions and methods thereof |
| CN108779132B (zh) | 2016-03-13 | 2022-04-15 | 波涛生命科学有限公司 | 用于亚磷酰胺和寡核苷酸合成的组合物和方法 |
| EP3452596A4 (en) | 2016-05-04 | 2020-03-18 | Wave Life Sciences Ltd. | OLIGONUCLEOTIDE COMPOSITIONS AND RELATED METHODS |
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| CA3072110A1 (en) | 2017-09-18 | 2019-03-21 | Wave Life Sciences Ltd. | Technologies for oligonucleotide preparation |
| EP3694530A4 (en) | 2017-10-12 | 2021-06-30 | Wave Life Sciences Ltd. | COMPOSITIONS OF OLIGONUCLEOTIDES AND RELATED PROCESSES |
| SG11202009877XA (en) | 2018-04-12 | 2020-11-27 | Wave Life Sciences Ltd | Oligonucleotide compositions and methods of use thereof |
| US12391942B2 (en) | 2018-05-11 | 2025-08-19 | Wave Life Sciences Ltd. | Oligonucleotide compositions and methods of use thereof |
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| MX2022014606A (es) | 2020-05-22 | 2023-03-08 | Wave Life Sciences Ltd | Composiciones de oligonucleótidos bicatenarios y métodos relacionados con las mismas. |
| EP4479535A1 (en) | 2022-02-14 | 2024-12-25 | ProQR Therapeutics II B.V. | Guide oligonucleotides for nucleic acid editing in the treatment of hypercholesterolemia |
| JP2025524566A (ja) | 2022-07-15 | 2025-07-30 | プロキューアール セラピューティクス ツー ベスローテン フェンノートシャップ | Ａｄａｒ媒介ｒｎａ編集のためのオリゴヌクレオチドおよびその使用 |
| US20260027237A1 (en) | 2022-07-15 | 2026-01-29 | Proqr Therapeutics Ii B.V. | Chemically modified oligonucleotides for adar-mediated rna editing |
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| AU2023390632A1 (en) | 2022-12-09 | 2025-07-10 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of cardiovascular disease |
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| WO2024175550A1 (en) | 2023-02-20 | 2024-08-29 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of atherosclerotic cardiovascular disease |
| EP4689110A1 (en) | 2023-03-24 | 2026-02-11 | ProQR Therapeutics II B.V. | Antisense oligonucleotides for the treatment of neurological disorders |
| GB202304363D0 (en) | 2023-03-24 | 2023-05-10 | Proqr Therapeutics Ii Bv | Chemically modified antisense oligonucleotides for use in RNA editing |
| EP4688143A1 (en) | 2023-03-27 | 2026-02-11 | ProQR Therapeutics II B.V. | Antisense oligonucleotides for the treatment of liver disease |
| TW202516003A (zh) | 2023-06-16 | 2025-04-16 | 荷蘭商Ｐｒｏｑｒ治療上市公司Ｉｉ | 用於治療神經退化性疾病之反義寡核苷酸 |
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| WO2025104239A1 (en) | 2023-11-16 | 2025-05-22 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of classic galactosemia |
| WO2025128799A1 (en) | 2023-12-12 | 2025-06-19 | Korro Bio, Inc. | Double-stranded rna-editing oligonucleotides and uses thereof |
| WO2025132708A1 (en) | 2023-12-20 | 2025-06-26 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of huntington's disease |
| GB202404661D0 (en) | 2024-04-02 | 2024-05-15 | Proqr Therapeutics Ii Bv | Antisense oligoncleotides for the treatment of liver disease |
| WO2025224230A1 (en) | 2024-04-25 | 2025-10-30 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of fatty liver disease |
| GB202410081D0 (en) | 2024-07-11 | 2024-08-28 | Proqr Therapeutics Ii Bv | Antisense oligonucleotides for the treatment of cardiovascular disease |
| WO2026022136A1 (en) | 2024-07-23 | 2026-01-29 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of metabolic disorders |
| WO2026050243A1 (en) | 2024-08-26 | 2026-03-05 | Korro Bio, Inc. | Galnac conjugated oligonucleotides for rna editing |
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| AU2023227808A1 (en) | 2022-03-02 | 2024-09-19 | Wave Life Sciences Ltd. | Oligonucleotide compositions and methods thereof for exon skipping |
| EP4507700A2 (en) | 2022-04-15 | 2025-02-19 | Wave Life Sciences Ltd. | Oligonucleotide compositions and methods relating thereto |
| US20250302995A1 (en) | 2022-05-12 | 2025-10-02 | Chikdu Shakti Shivalila | Oligonucleotide compositions and methods thereof |
| AU2023321711A1 (en) | 2022-08-11 | 2025-02-20 | Wave Life Sciences Ltd. | Oligonucleotide compositions and methods thereof |
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2018
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- 2018-09-17 AU AU2018333065A patent/AU2018333065B2/en active Active
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- 2018-09-17 WO PCT/US2018/051398 patent/WO2019055951A1/en not_active Ceased
- 2018-09-17 EP EP18856608.7A patent/EP3684755A4/en active Pending
- 2018-09-17 CN CN201880057920.3A patent/CN111108096A/zh active Pending
- 2018-09-17 KR KR1020257025660A patent/KR20250123934A/ko active Pending
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2023
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