|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
WO1988001513A1
(fr)
|
1986-08-28 |
1988-03-10 |
Teijin Limited |
Complexe d'anticorps cytocide et procede de production
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5151510A
(en)
|
1990-04-20 |
1992-09-29 |
Applied Biosystems, Inc. |
Method of synethesizing sulfurized oligonucleotide analogs
|
|
ES2091684T3
(es)
|
1992-11-13 |
1996-11-01 |
Idec Pharma Corp |
Aplicacion terapeutica de anticuerpos quimericos y radiomarcados contra el antigeno de diferenciacion restringida de los linfocitos b humanos para el tratamiento del linfoma de las celulas b.
|
|
EP1210428B1
(en)
|
1999-08-23 |
2015-03-18 |
Dana-Farber Cancer Institute, Inc. |
Pd-1, a receptor for b7-4, and uses therefor
|
|
JP5004390B2
(ja)
|
1999-08-23 |
2012-08-22 |
デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド |
新規ｂ７−４分子およびその用途
|
|
US6803192B1
(en)
|
1999-11-30 |
2004-10-12 |
Mayo Foundation For Medical Education And Research |
B7-H1, a novel immunoregulatory molecule
|
|
PT1234031T
(pt)
|
1999-11-30 |
2017-06-26 |
Mayo Foundation |
B7-h1, uma nova molécula imunoregulatória
|
|
EP1286700A2
(en)
|
2000-06-01 |
2003-03-05 |
Universite Catholique De Louvain |
Tumor activated prodrug compounds
|
|
JP2004501624A
(ja)
|
2000-06-28 |
2004-01-22 |
ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー |
Ｐｄ−ｌ２分子：新規ｐｄ−１リガンドおよびその使用
|
|
US7465790B2
(en)
|
2000-10-09 |
2008-12-16 |
Isis Innovation, Inc. |
Therapeutic antibodies
|
|
AU9399501A
(en)
|
2000-10-09 |
2002-04-22 |
Isis Innovation |
Therapeutic antibodies
|
|
EP2388590A1
(en)
|
2001-04-02 |
2011-11-23 |
Dana Farber Cancer Institute |
PD-1, a receptor for B7-4, and uses thereof
|
|
WO2002086083A2
(en)
|
2001-04-20 |
2002-10-31 |
Mayo Foundation For Medical Education And Research |
Methods of enhancing cell responsiveness
|
|
CA2466279A1
(en)
|
2001-11-13 |
2003-05-22 |
Dana-Farber Cancer Institute, Inc. |
Agents that modulate immune cell activation and methods of use thereof
|
|
AU2003281200A1
(en)
|
2002-07-03 |
2004-01-23 |
Tasuku Honjo |
Immunopotentiating compositions
|
|
US20040109855A1
(en)
|
2002-07-23 |
2004-06-10 |
Herman Waldmann |
Therapeutic antibodies with reduced side effect
|
|
WO2004021861A2
(en)
|
2002-09-03 |
2004-03-18 |
Vit Lauermann |
Targeted release
|
|
US7432351B1
(en)
|
2002-10-04 |
2008-10-07 |
Mayo Foundation For Medical Education And Research |
B7-H1 variants
|
|
US7449300B2
(en)
|
2002-11-21 |
2008-11-11 |
Mayo Foundation For Medical Education And Research |
Detection of antibodies specific for B7-H1 in subjects with diseases or pathological conditions mediated by activated T cells
|
|
PT3428191T
(pt)
|
2004-10-06 |
2024-12-30 |
Mayo Found Medical Education & Res |
B7-h1 e tratamento do carcinona de células renais
|
|
CN109485727A
(zh)
|
2005-05-09 |
2019-03-19 |
小野药品工业株式会社 |
程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法
|
|
EP3130350A1
(en)
|
2005-06-08 |
2017-02-15 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1)pathway
|
|
KR101411165B1
(ko)
|
2005-07-01 |
2014-06-25 |
메다렉스, 엘.엘.시. |
예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날항체
|
|
AU2006284651C1
(en)
|
2005-08-31 |
2013-09-12 |
The Regents Of The University Of California |
Cellular libraries of peptide sequences (CLiPS) and methods of using the same
|
|
CA2645347A1
(en)
|
2006-03-10 |
2007-09-20 |
Diatos |
Anticancer drugs conjugated to antibody via an enzyme cleavable linker
|
|
NZ720288A
(en)
|
2006-12-27 |
2020-02-28 |
Harvard College |
Compositions and methods for the treatment of infections and tumors
|
|
CA2673659A1
(en)
|
2006-12-27 |
2008-07-10 |
The Johns Hopkins University |
Methods of detecting and diagnosing inflamatory responses and disorders by determining the level of soluble b7-h4
|
|
NZ600758A
(en)
|
2007-06-18 |
2013-09-27 |
Merck Sharp & Dohme |
Antibodies to human programmed death receptor pd-1
|
|
EP3492488A1
(en)
|
2007-08-22 |
2019-06-05 |
The Regents of The University of California |
Activatable binding polypeptides and methods of identification and use thereof
|
|
US8062852B2
(en)
|
2007-10-01 |
2011-11-22 |
The Children's Hospital And Regional Medical Center |
Detection and treatment of autoimmune disorders
|
|
ES2592216T3
(es)
|
2008-09-26 |
2016-11-28 |
Dana-Farber Cancer Institute, Inc. |
Anticuerpos anti-PD-1, PD-L1 y PD-L2 humanos y sus usos
|
|
KR101050829B1
(ko)
|
2008-10-02 |
2011-07-20 |
서울대학교산학협력단 |
항 ｐｄ-1 항체 또는 항 ｐｄ-ｌ1 항체를 포함하는 항암제
|
|
CN102282265B
(zh)
|
2008-11-28 |
2020-07-24 |
埃默里大学 |
用于治疗传染病和肿瘤的方法
|
|
EP2356131A4
(en)
|
2008-12-08 |
2012-09-12 |
Tegopharm Corp |
MASKING LIGANDS FOR REVERSIBLE INHIBITION OF VERSATILE COMPOUNDS
|
|
WO2010077634A1
(en)
|
2008-12-09 |
2010-07-08 |
Genentech, Inc. |
Anti-pd-l1 antibodies and their use to enhance t-cell function
|
|
WO2010081173A2
(en)
|
2009-01-12 |
2010-07-15 |
Cytomx Therapeutics, Llc |
Modified antibody compositions, methods of making and using thereof
|
|
US8741295B2
(en)
|
2009-02-09 |
2014-06-03 |
Universite De La Mediterranee |
PD-1 antibodies and PD-L1 antibodies and uses thereof
|
|
NZ599405A
(en)
|
2009-11-24 |
2014-09-26 |
Medimmune Ltd |
Targeted binding agents against b7-h1
|
|
IL300733B1
(en)
|
2010-03-05 |
2025-10-01 |
Univ Johns Hopkins |
Compositions and methods for antibodies and fusion proteins targeted for immune modulation
|
|
CA2792561C
(en)
|
2010-04-06 |
2021-10-26 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of cd274/pd-l1 gene
|
|
US20110280877A1
(en)
|
2010-05-11 |
2011-11-17 |
Koji Tamada |
Inhibition of B7-H1/CD80 interaction and uses thereof
|
|
US8962804B2
(en)
|
2010-10-08 |
2015-02-24 |
City Of Hope |
Meditopes and meditope-binding antibodies and uses thereof
|
|
TWI803876B
(zh)
|
2011-03-28 |
2023-06-01 |
法商賽諾菲公司 |
具有交叉結合區定向之雙重可變區類抗體結合蛋白
|
|
PL2699264T3
(pl)
|
2011-04-20 |
2018-08-31 |
Medimmune, Llc |
Przeciwciała i inne cząsteczki wiążące B7-H1 i PD-1
|
|
AR087405A1
(es)
|
2011-08-01 |
2014-03-19 |
Genentech Inc |
Metodos para tratar el cancer por el uso de antagonistas de union al eje pd-1 e inhibidores de mek
|
|
US20130071403A1
(en)
|
2011-09-20 |
2013-03-21 |
Vical Incorporated |
Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
|
|
US8956619B2
(en)
|
2011-10-25 |
2015-02-17 |
University Of Maryland, Baltimore County |
Soluble CD80 as a therapeutic to reverse immune supression in cancer patients
|
|
EP2785375B1
(en)
|
2011-11-28 |
2020-07-22 |
Merck Patent GmbH |
Anti-pd-l1 antibodies and uses thereof
|
|
GB201203442D0
(en)
|
2012-02-28 |
2012-04-11 |
Univ Birmingham |
Immunotherapeutic molecules and uses
|
|
AU2013251310B2
(en)
|
2012-04-27 |
2018-02-15 |
Cytomx Therapeutics, Inc. |
Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
|
|
US9856320B2
(en)
|
2012-05-15 |
2018-01-02 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting PD-1/PD-L1 signaling
|
|
CN104736168B
(zh)
|
2012-05-31 |
2018-09-21 |
索伦托治疗有限公司 |
与pd-l1结合的抗原结合蛋白
|
|
US9856314B2
(en)
|
2012-06-22 |
2018-01-02 |
Cytomx Therapeutics, Inc. |
Activatable antibodies having non-binding steric moieties and methods of using the same
|
|
US9845356B2
(en)
|
2012-08-03 |
2017-12-19 |
Dana-Farber Cancer Institute, Inc. |
Single agent anti-PD-L1 and PD-L2 dual binding antibodies and methods of use
|
|
US9309510B2
(en)
|
2012-08-10 |
2016-04-12 |
Cytomx Therapeutics, Inc. |
Protease-resistant systems for polypeptide display and methods of making and using thereof
|
|
JP6461800B2
(ja)
|
2012-10-04 |
2019-01-30 |
デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド |
ヒトモノクローナル抗ｐｄ−ｌ１抗体および使用方法
|
|
WO2014066834A1
(en)
|
2012-10-26 |
2014-05-01 |
The University Of Chicago |
Synergistic combination of immunologic inhibitors for the treatment of cancer
|
|
WO2014074852A1
(en)
|
2012-11-09 |
2014-05-15 |
President And Fellows Of Harvard College |
Compositions and methods for modulating an immune response
|
|
BR112015012644A2
(pt)
|
2012-11-30 |
2017-12-19 |
Hoffmann La Roche |
método para determinar a necessidade de um paciente com câncer, método de tratamento do câncer, composição farmacêutica, uso de um ácido nucleico ou anticorpo e kit;
|
|
EP2934575A2
(en)
|
2012-12-19 |
2015-10-28 |
Amplimmune, Inc. |
B7-h4 specific antibodies, and compositions and methods of use thereof
|
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
|
CN112162094A
(zh)
|
2013-01-04 |
2021-01-01 |
西托姆克斯治疗公司 |
用于检测生物系统中的蛋白酶活性的组合物和方法
|
|
WO2014107873A1
(zh)
|
2013-01-11 |
2014-07-17 |
苏州丁孚靶点生物技术有限公司 |
用于肿瘤治疗的试剂、其用途及方法
|
|
EP2948475A2
(en)
|
2013-01-23 |
2015-12-02 |
AbbVie Inc. |
Methods and compositions for modulating an immune response
|
|
AU2014214843A1
(en)
|
2013-02-07 |
2015-05-21 |
Immunomedics, Inc. |
Pro-drug form (P2PDox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer
|
|
WO2014165082A2
(en)
|
2013-03-13 |
2014-10-09 |
Medimmune, Llc |
Antibodies and methods of detection
|
|
JP6483082B2
(ja)
|
2013-03-15 |
2019-03-13 |
ジェネンテック， インコーポレイテッド |
Ｐｄ−１及びｐｄ−ｌ１に関連する状態を治療するためのバイオマーカー及び方法
|
|
AR095363A1
(es)
|
2013-03-15 |
2015-10-14 |
Genentech Inc |
Biomarcadores y métodos para el tratamiento de condiciones relacionadas con pd-1 y pd-l1
|
|
CN111423511B
(zh)
|
2013-05-31 |
2024-02-23 |
索伦托药业有限公司 |
与pd-1结合的抗原结合蛋白
|
|
KR20160013049A
(ko)
|
2013-06-03 |
2016-02-03 |
노파르티스 아게 |
항-pd-l1 항체 및 mek 억제제 및/또는 braf 억제제의 조합물
|
|
EP3004877A4
(en)
|
2013-06-06 |
2017-04-19 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment prevention, and treatment of cancer using pd-l1 isoforms
|
|
CN104250302B
(zh)
|
2013-06-26 |
2017-11-14 |
上海君实生物医药科技股份有限公司 |
抗pd‑1抗体及其应用
|
|
FR3008408B1
(fr)
|
2013-07-11 |
2018-03-09 |
Mc Saf |
Nouveaux conjugues anticorps-medicament et leur utilisation en therapie
|
|
CA2918795A1
(en)
|
2013-07-25 |
2015-01-29 |
Cytomx Therapeutics, Inc. |
Multispecific antibodies, multispecific activatable antibodies and methods of using the same
|
|
WO2015035112A1
(en)
|
2013-09-05 |
2015-03-12 |
The Johns Hopkins University |
Cancer therapy via a combination of epigenetic modulation and immune modulation
|
|
WO2015038538A1
(en)
|
2013-09-10 |
2015-03-19 |
Medimmune, Llc |
Compositions and methods for treating sepsis
|
|
RU2701327C2
(ru)
|
2013-09-11 |
2019-09-25 |
Медиммьюн Лимитед |
Антитела к b7-h1 для лечения опухолей
|
|
AR097584A1
(es)
|
2013-09-12 |
2016-03-23 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano
|
|
ES2792183T3
(es)
|
2013-09-13 |
2020-11-10 |
Beigene Switzerland Gmbh |
Anticuerpos anti-PD1 y su uso como productos terapéuticos y de diagnóstico
|
|
EP3757130A1
(en)
|
2013-09-26 |
2020-12-30 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
RS59880B1
(sr)
|
2013-09-27 |
2020-03-31 |
Hoffmann La Roche |
Formulacije za anti-pdl1 antitelo
|
|
US10259875B2
(en)
|
2013-10-01 |
2019-04-16 |
Mayo Foundation For Medical Education And Research |
Methods for treating cancer in patients with elevated levels of BIM
|
|
US10202454B2
(en)
|
2013-10-25 |
2019-02-12 |
Dana-Farber Cancer Institute, Inc. |
Anti-PD-L1 monoclonal antibodies and fragments thereof
|
|
KR20160093012A
(ko)
|
2013-11-05 |
2016-08-05 |
코그네이트 바이오서비시즈, 인코포레이티드 |
암 치료를 위한 체크포인트 억제제 및 치료제의 배합물
|
|
WO2015069697A2
(en)
|
2013-11-05 |
2015-05-14 |
Nkt Therapeutics Inc. |
Combination therapy
|
|
EP3074035B1
(en)
|
2013-11-25 |
2020-05-13 |
FameWave Ltd. |
Compositions comprising anti-ceacam1 and anti-pd antibodies for cancer therapy
|
|
WO2015081158A1
(en)
|
2013-11-26 |
2015-06-04 |
Bristol-Myers Squibb Company |
Method of treating hiv by disrupting pd-1/pd-l1 signaling
|
|
US10241115B2
(en)
|
2013-12-10 |
2019-03-26 |
Merck Sharp & Dohme Corp. |
Immunohistochemical proximity assay for PD-1 positive cells and PD-ligand positive cells in tumor tissue
|
|
US20160303231A1
(en)
|
2013-12-11 |
2016-10-20 |
Robert Iannone |
Treating cancer with a combination of a pd-1 antagonist and a vegfr inhibitor
|
|
KR102630750B1
(ko)
|
2013-12-17 |
2024-01-30 |
제넨테크, 인크. |
Pd-1 축 결합 길항제 및 탁산을 이용한 암 치료 방법
|
|
WO2015092394A1
(en)
|
2013-12-17 |
2015-06-25 |
Kymab Limited |
Antibodies for use in treating conditions related to specific pcsk9 variants in specific patients populations
|
|
US9067998B1
(en)
|
2014-07-15 |
2015-06-30 |
Kymab Limited |
Targeting PD-1 variants for treatment of cancer
|
|
US9914769B2
(en)
|
2014-07-15 |
2018-03-13 |
Kymab Limited |
Precision medicine for cholesterol treatment
|
|
KR20160089532A
(ko)
|
2013-12-17 |
2016-07-27 |
제넨테크, 인크. |
Pd-1 축 결합 길항제 및 항-cd20 항체를 사용하여 암을 치료하는 방법
|
|
US9045545B1
(en)
|
2014-07-15 |
2015-06-02 |
Kymab Limited |
Precision medicine by targeting PD-L1 variants for treatment of cancer
|
|
US8992927B1
(en)
|
2014-07-15 |
2015-03-31 |
Kymab Limited |
Targeting human NAV1.7 variants for treatment of pain
|
|
HRP20201906T1
(hr)
|
2013-12-20 |
2021-04-02 |
Fred Hutchinson Cancer Research Center |
Označene kimerne efektorske molekule i njihovi receptori
|
|
ES2923641T3
(es)
|
2013-12-30 |
2022-09-29 |
Epimab Biotherapeutics Inc |
Inmunoglobulina con Fabs en tándem y usos de la misma
|
|
EP4070818A3
(en)
|
2014-01-06 |
2023-01-11 |
The Trustees of the University of Pennsylvania |
Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy
|
|
AU2015205530B8
(en)
|
2014-01-13 |
2019-09-19 |
Pieris Pharmaceuticals Gmbh |
Multi-specific polypeptide useful for localized tumor immunomodulation
|
|
EP3094736A4
(en)
|
2014-01-14 |
2017-10-25 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment, prevention, and treatment of melanoma using pd-l1 isoforms
|
|
CN105263521B
(zh)
|
2014-01-15 |
2021-06-29 |
卡德门企业有限公司 |
免疫调节剂
|
|
CA2936244A1
(en)
|
2014-01-21 |
2015-07-30 |
Medimmune, Llc |
Compositions and methods for modulating and redirecting immune responses
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗ｐｄ-ｌ１之人類抗體
|
|
SG11201606577YA
(en)
|
2014-02-10 |
2016-09-29 |
Merck Patent Gmbh |
TARGETED TGFβ INHIBITION
|
|
US10519237B2
(en)
|
2014-03-12 |
2019-12-31 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
WO2015157162A1
(en)
|
2014-04-06 |
2015-10-15 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Histone deacetylase as a modulator of pdl1 expression and activity
|
|
EP3603748A1
(en)
|
2014-05-13 |
2020-02-05 |
MedImmune Limited |
Anti-b7-h1 and anti-ctla-4 antibodies for treating non-small cell lung cancer
|
|
US11505605B2
(en)
|
2014-05-13 |
2022-11-22 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirected antigen-binding molecule for cells having immunosuppression function
|
|
WO2015179654A1
(en)
|
2014-05-22 |
2015-11-26 |
Mayo Foundation For Medical Education And Research |
Distinguishing antagonistic and agonistic anti b7-h1 antibodies
|
|
KR20150135148A
(ko)
|
2014-05-23 |
2015-12-02 |
주식회사 제넥신 |
Pd-l1 융합 단백질 및 이의 용도
|
|
US9885721B2
(en)
|
2014-05-29 |
2018-02-06 |
Spring Bioscience Corporation |
PD-L1 antibodies and uses thereof
|
|
RU2016151757A
(ru)
|
2014-05-29 |
2018-07-02 |
Медиммьюн Лимитед |
Антагонисты pdl-1 и pd-1 для лечения hpv-отрицательных форм рака
|
|
WO2015181343A2
(en)
|
2014-05-30 |
2015-12-03 |
Ventana Medical Systems, Inc. |
Multiplex assay for improved scoring of tumor tissues stained for pd-l1
|
|
WO2015195163A1
(en)
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Pd-l1 antagonist fully human antibody
|
|
US10449227B2
(en)
|
2014-06-27 |
2019-10-22 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Conjugates for immunotherapy
|
|
CN106604742B
(zh)
|
2014-07-03 |
2019-01-11 |
百济神州有限公司 |
抗pd-l1抗体及其作为治疗剂及诊断剂的用途
|
|
EP4001311B1
(en)
|
2014-07-09 |
2025-11-05 |
Birdie Biopharmaceuticals Inc. |
Anti-pd-l1/pd-1 combinations for treating tumors
|
|
EP3168236B1
(en)
|
2014-07-09 |
2019-09-04 |
Nippon Zenyaku Kogyo Co., Ltd. |
Anti-canine pd-1 antibody or anti-canine pd-l1 antibody
|
|
CN112546231A
(zh)
|
2014-07-09 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗癌症的联合治疗组合物和联合治疗方法
|
|
EP3309174B1
(en)
|
2014-07-11 |
2022-05-11 |
Ventana Medical Systems, Inc. |
Anti-pd-l1 antibodies and diagnostic uses thereof
|
|
US9139648B1
(en)
|
2014-07-15 |
2015-09-22 |
Kymab Limited |
Precision medicine by targeting human NAV1.9 variants for treatment of pain
|
|
JP6843736B2
(ja)
|
2014-07-16 |
2021-03-17 |
トランジェーヌＴｒａｎｓｇｅｎｅ |
腫瘍溶解性ウイルスと免疫チェックポイントモジュレーターとの組合せ
|
|
MX2017000857A
(es)
|
2014-07-18 |
2017-10-11 |
Advaxis Inc |
Combinación de un antagonista de la proteina de muerte programada (pd-1) y una vacuna basada en listeria para tratar el cáncer de próstata.
|
|
SG10201901057UA
(en)
|
2014-08-05 |
2019-03-28 |
Cb Therapeutics Inc |
Anti-pd-l1 antibodies
|
|
CN106687124B
(zh)
|
2014-08-07 |
2022-03-15 |
冈村春树 |
并用il-18与分子靶向抗体的癌治疗药
|
|
EP3070102A1
(en)
|
2015-03-18 |
2016-09-21 |
F. Hoffmann-La Roche AG |
Combination therapy of antibodies human cd40 activating antibodies and anti human pld-1 antibodies
|
|
SG11201701039PA
(en)
|
2014-08-14 |
2017-03-30 |
Hoffmann La Roche |
Combination therapy of antibodies activating human cd40 and antibodies against human pd-l1
|
|
WO2016030455A1
(en)
|
2014-08-28 |
2016-03-03 |
Medimmune Limited |
Anti-b7-h1 and anti-ctla-4 antibodies for treating non-small lung cancer
|
|
AU2015308527C1
(en)
|
2014-08-29 |
2021-07-15 |
F. Hoffmann-La Roche Ag |
Combination therapy of tumor-targeted IL-2 variant immunocytokines and antibodies against human PD-L1
|
|
CN112546238A
(zh)
|
2014-09-01 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
WO2016040238A1
(en)
|
2014-09-08 |
2016-03-17 |
Celgene Corporation |
Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-pd1 or anti-pdl1 monoclonal antibody
|
|
ES2853823T3
(es)
|
2014-09-30 |
2021-09-17 |
Intervet Int Bv |
Anticuerpos de PD-L1 que se unen a PD-L1 canino
|
|
MX389663B
(es)
|
2014-10-14 |
2025-03-20 |
Novartis Ag |
Moleculas de anticuerpo que se unen a pd-l1 y usos de las mismas.
|
|
WO2016059602A2
(en)
|
2014-10-16 |
2016-04-21 |
Glaxo Group Limited |
Methods of treating cancer and related compositions
|
|
WO2016065038A1
(en)
|
2014-10-23 |
2016-04-28 |
Five Prime Therapeutics, Inc. |
Slamf1 antagonists and uses thereof
|
|
CN107106590B
(zh)
|
2014-10-24 |
2022-10-18 |
阿斯利康(瑞典)有限公司 |
组合
|
|
US9765147B2
(en)
|
2014-10-29 |
2017-09-19 |
Five Prime Therapeutics, Inc. |
Anti-CSFR1 antibody and anti PD-1 antibody combination therapy for cancer
|
|
MX382902B
(es)
|
2014-10-31 |
2025-03-13 |
Oncomed Pharm Inc |
Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer.
|
|
WO2016071701A1
(en)
|
2014-11-07 |
2016-05-12 |
Kymab Limited |
Treatment of disease using ligand binding to targets of interest
|
|
KR20170082579A
(ko)
|
2014-11-11 |
2017-07-14 |
메디뮨 리미티드 |
종양을 치료하기 위한 치료 조합
|
|
WO2016079049A1
(en)
|
2014-11-17 |
2016-05-26 |
Medimmune Limited |
Therapeutic combinations and methods for treating neoplasia
|
|
CN105777906B
(zh)
|
2014-12-19 |
2019-04-23 |
苏州丁孚靶点生物技术有限公司 |
抗pd-l1全人抗体及其应用
|
|
WO2016104657A1
(ja)
|
2014-12-26 |
2016-06-30 |
橋本 正 |
癌治療剤
|
|
CA2972757A1
(en)
|
2014-12-31 |
2016-07-07 |
Arthur M. Krieg |
Combination tumor immunotherapy
|
|
GB201500319D0
(en)
|
2015-01-09 |
2015-02-25 |
Agency Science Tech & Res |
Anti-PD-L1 antibodies
|
|
JP2018503399A
(ja)
|
2015-01-14 |
2018-02-08 |
コンパス セラピューティクス リミテッド ライアビリティ カンパニー |
多特異性免疫調節抗原結合構築物
|
|
WO2016112870A1
(en)
|
2015-01-16 |
2016-07-21 |
Tse-Wen Chang |
Molecular constructs with targeting and effector elements
|
|
KR20240132103A
(ko)
|
2015-01-29 |
2024-09-02 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
관문 억제제 및 백신 조합 및 면역요법을 위한 이들의 사용
|
|
ES2791950T3
(es)
|
2015-02-03 |
2020-11-06 |
Ventana Med Syst Inc |
Ensayo histoquímico para evaluar la expresión del ligando de muerte programada 1 (PD-L1)
|
|
MA41460A
(fr)
|
2015-02-03 |
2017-12-12 |
Oncomed Pharm Inc |
Agents de liaison à la tnfrsf et leurs utilisations
|
|
WO2016128912A1
(en)
|
2015-02-12 |
2016-08-18 |
Acerta Pharma B.V. |
Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, a pd-1 inhibitor, and/or a pd-l1 inhibitor
|
|
CN112263677A
(zh)
|
2015-02-26 |
2021-01-26 |
默克专利股份公司 |
用于治疗癌症的pd-1/pd-l1抑制剂
|
|
CA2977532A1
(en)
|
2015-03-06 |
2016-09-15 |
Dana-Farber Cancer Institute, Inc. |
Pd-l2 biomarkers predictive of pd-1 pathway inhibitor responses in esophagogastric cancers
|
|
EP3067062A1
(en)
|
2015-03-13 |
2016-09-14 |
Ipsen Pharma S.A.S. |
Combination of tasquinimod or a pharmaceutically acceptable salt thereof and a pd1 and/or pdl1 inhibitor, for use as a medicament
|
|
MX2017011644A
(es)
|
2015-03-13 |
2017-12-04 |
Cytomx Therapeutics Inc |
Anticuerpos anti-pdl1, anticuerpos anti-pdl1 activables y metodos de uso de los mismos.
|
|
WO2016154412A2
(en)
|
2015-03-26 |
2016-09-29 |
The Trustees Of The University Of Pennsylvania |
Combination of a pd-1 antagonist and a listeria based vaccine for treating pancreatic cancer
|
|
US20180085398A1
(en)
|
2015-03-30 |
2018-03-29 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of treating cancer
|
|
US20180078650A1
(en)
|
2015-03-30 |
2018-03-22 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of treating acute myeloid leukemia
|
|
JP6936784B2
(ja)
|
2015-03-30 |
2021-09-22 |
エスティーキューブ，インコーポレイテッド |
グリコシル化ｐｄ−ｌ１に特異的な抗体およびその使用方法
|
|
CA2977749A1
(en)
|
2015-03-30 |
2016-10-06 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of treating renal cell cancer
|
|
US11026921B2
(en)
|
2015-03-30 |
2021-06-08 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of treating cancer
|
|
US20180071340A1
(en)
|
2015-03-30 |
2018-03-15 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of treating multiple myeloma
|
|
HK1247578A1
(zh)
|
2015-04-01 |
2018-09-28 |
Medimmune Limited |
用於治疗非小细胞肺癌的组合抗pd-l1和抗ctla4抗体
|
|
EP3286213B1
(en)
|
2015-04-20 |
2021-08-04 |
Etubics Corporation |
Methods and compositions for combination immunotherapy
|
|
JP2018515450A
(ja)
|
2015-04-23 |
2018-06-14 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
アンジオポイエチン２に結合する抗体のプログラムデスリガンド１に結合する抗体との併用療法
|
|
US10585100B2
(en)
|
2015-04-30 |
2020-03-10 |
Kyoto University |
Method of predicting effect of treatment by PD-1/PD-L1 blockade using abnormality of PD-L1 (CD274) as index
|
|
WO2016183326A1
(en)
|
2015-05-12 |
2016-11-17 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
WO2016181348A1
(en)
|
2015-05-14 |
2016-11-17 |
Pfizer Inc. |
Combinations comprising a pyrrolidine-2,5-dione ido1 inhibitor and an anti-body
|
|
US20160347848A1
(en)
|
2015-05-28 |
2016-12-01 |
Medimmune Limited |
Therapeutic combinations and methods for treating neoplasia
|
|
US11078278B2
(en)
|
2015-05-29 |
2021-08-03 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
EP3303619B1
(en)
|
2015-05-29 |
2020-06-10 |
H. Hoffnabb-La Roche Ag |
Pd-l1 promoter methylation in cancer
|
|
CN106243225B
(zh)
|
2015-06-11 |
2021-01-19 |
智翔（上海）医药科技有限公司 |
新型抗-pd-l1抗体
|
|
EP3307777A4
(en)
|
2015-06-11 |
2019-02-13 |
Wuxi Biologics (Shanghai) Co. Ltd. |
NOVEL ANTI-PD-L1 ANTIBODIES
|
|
MY193229A
(en)
|
2015-06-16 |
2022-09-26 |
Merck Patent GmbH |
Pd-l1 antagonist combination treatments
|
|
ES2987376T3
(es)
|
2015-06-29 |
2024-11-14 |
Verastem Inc |
Composiciones terapéuticas, combinaciones y métodos de uso
|
|
KR20180025865A
(ko)
|
2015-07-06 |
2018-03-09 |
리제너론 파마슈티칼스 인코포레이티드 |
다중특이적 항원 결합 분자 및 이의 용도
|
|
PL3322731T3
(pl)
|
2015-07-14 |
2021-05-31 |
Bristol-Myers Squibb Company |
Sposób leczenia raka inhibitorem immunologicznych punktów kontrolnych; przeciwciałem, które wiąże się z receptorem programowanej śmierci-1 (pd-1) lub ligandem receptora programowanej śmierci 1 (pd-l1)
|
|
US20170021019A1
(en)
|
2015-07-22 |
2017-01-26 |
Matthew Zibelman |
COMBINATION OF IMMUNOMODULATORY AGENT WITH PD-1 or PD-L1 CHECKPOINT INHIBITORS IN THE TREATMENT OF CANCER
|
|
CN106397592A
(zh)
|
2015-07-31 |
2017-02-15 |
苏州康宁杰瑞生物科技有限公司 |
针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白
|
|
WO2017020291A1
(en)
|
2015-08-06 |
2017-02-09 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
US20180230431A1
(en)
|
2015-08-07 |
2018-08-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination Therapy
|
|
AR105654A1
(es)
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
|
US11639389B2
(en)
|
2015-09-30 |
2023-05-02 |
Igm Biosciences, Inc. |
Binding molecules with modified J-chain
|
|
US20180296561A1
(en)
|
2015-10-07 |
2018-10-18 |
The University Of North Carolina At Chapel Hill |
The Methods For Treatment Of Tumors
|
|
JP6850290B2
(ja)
|
2015-10-15 |
2021-03-31 |
デューク ユニバーシティー |
併用療法
|
|
US10364280B2
(en)
|
2015-10-30 |
2019-07-30 |
Affibody Ab |
Polypeptide
|
|
MX382321B
(es)
|
2015-10-30 |
2025-03-13 |
Affibody Ab |
Nuevo polipéptido con afinidad por pd-l1.
|
|
CA3004804A1
(en)
|
2015-11-17 |
2017-05-26 |
Jiangsu Hengrui Medicine Co., Ltd. |
Pd-l1 antibody, antigen-binding fragment thereof and medical application thereof
|
|
US20180346571A1
(en)
|
2015-11-17 |
2018-12-06 |
Oncomed Pharmaceuticals, Inc. |
Pd-l1-binding agents and uses thereof
|
|
JP6952691B2
(ja)
*
|
2015-11-19 |
2021-10-20 |
ジェネンテック， インコーポレイテッド |
Ｂ−ｒａｆ阻害剤及び免疫チェックポイント阻害剤を使用してがんを治療する方法
|
|
US20180362650A1
(en)
|
2015-12-07 |
2018-12-20 |
Kyoto University |
Pd-1 signal inhibitor combination therapy
|
|
PL3386541T3
(pl)
|
2015-12-07 |
2021-04-06 |
Merck Patent Gmbh |
Wodna formulacja farmaceutyczna zawierającą przeciwciało anty-pd-1 awelumab
|
|
CN105461808B
(zh)
|
2015-12-24 |
2019-03-19 |
长春金赛药业股份有限公司 |
单克隆抗体及其应用
|
|
US20190022129A1
(en)
|
2016-01-08 |
2019-01-24 |
Biothera, Inc. |
Beta-glucan immunotherapies affecting the immune microenvironment
|
|
SG11201805422WA
(en)
|
2016-01-11 |
2018-07-30 |
Inhibrx Inc |
Multivalent and multispecific ox40-binding fusion proteins
|
|
CN109310755A
(zh)
|
2016-02-02 |
2019-02-05 |
卡德门企业有限公司 |
Pd-l1和kdr的双特异性结合蛋白
|
|
AU2017214692B2
(en)
|
2016-02-06 |
2021-11-04 |
Epimab Biotherapeutics, Inc. |
Fabs-in-tandem immunoglobulin and uses thereof
|
|
AU2017226510C1
(en)
|
2016-03-04 |
2019-05-16 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
A pdl-1 antibody, pharmaceutical composition thereof and use thereof
|
|
WO2017161154A2
(en)
|
2016-03-16 |
2017-09-21 |
H. Lee Moffitt Cancer Center & Research Institute, Inc. |
Pd1 and pdl-1 expression during progression from myelodysplastic syndrome to acute myelogenous leukemia
|
|
RU2744959C2
(ru)
|
2016-03-23 |
2021-03-17 |
Мэбспейс Байосайнсиз (Сучжоу) Ко., Лтд |
Новые анти-pd-l1 антитела
|
|
JP7241541B2
(ja)
|
2016-03-29 |
2023-03-17 |
エスティーキューブ，インコーポレイテッド |
グリコシル化ｐｄ－ｌ１に特異的な二重機能抗体およびその使用方法
|
|
PL3439653T3
(pl)
|
2016-04-07 |
2021-07-05 |
Chemocentryx, Inc. |
Zmniejszenie obciążenia guzem przez podawanie antagonistów ccr1 w skojarzeniu z inhibitorami pd-1 lub inhibitorami pd-l1
|
|
EP3440109B1
(en)
|
2016-04-07 |
2025-07-23 |
Cancer Research Technology Limited |
Anti cd25 fc gamma receptor antibodies for tumor specific cell depletion in combination with pd-1 antagonists
|
|
JP2019513737A
(ja)
|
2016-04-08 |
2019-05-30 |
ギリアード サイエンシーズ， インコーポレイテッド |
がん、炎症性疾患および自己免疫疾患を処置するための組成物および方法
|
|
KR20190003958A
(ko)
|
2016-04-15 |
2019-01-10 |
제넨테크, 인크. |
암의 치료 및 모니터링 방법
|
|
JP2019514889A
(ja)
|
2016-04-25 |
2019-06-06 |
メディミューン，エルエルシー |
抗ｐｄ−ｌ１および抗ｃｔｌａ−４抗体の共製剤を含む組成物
|
|
JP2019514969A
(ja)
|
2016-05-04 |
2019-06-06 |
エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド |
分子イメージング及びがんの免疫療法のためのδオピオイド受容体標的化薬
|
|
CN120350015A
(zh)
|
2016-05-05 |
2025-07-22 |
宾夕法尼亚大学理事会 |
靶向检查点分子的dna单克隆抗体
|
|
AR108377A1
(es)
|
2016-05-06 |
2018-08-15 |
Medimmune Llc |
Proteínas de unión biespecíficas y sus usos
|
|
WO2017196867A1
(en)
|
2016-05-09 |
2017-11-16 |
Igm Biosciences, Inc. |
Anti-pd-l1 antibodies
|
|
TWI794171B
(zh)
|
2016-05-11 |
2023-03-01 |
美商滬亞生物國際有限公司 |
Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
|
|
EP3458481A4
(en)
|
2016-05-18 |
2020-07-29 |
Mayo Foundation for Medical Education and Research |
TARGETING PD-L1 ON TUMOR CELLS
|
|
HRP20240617T1
(hr)
|
2016-05-20 |
2024-07-19 |
Biohaven Therapeutics Ltd. |
Primjena riluzola, prolijekova riluzola ili analoga riluzola sa imunoterapijama za liječenje raka
|
|
WO2017202744A1
(en)
|
2016-05-26 |
2017-11-30 |
Merck Patent Gmbh |
Pd-1 / pd-l1 inhibitors for cancer treatment
|
|
WO2017205801A1
(en)
|
2016-05-27 |
2017-11-30 |
Takeda Pharmaceutical Company Limited |
Combination of immunotherapy agents and spleen tyrosine kinase inhibitors
|
|
CN107459578B
(zh)
|
2016-05-31 |
2021-11-26 |
泰州迈博太科药业有限公司 |
一种靶向cd47与pd-l1的双功能融合蛋白
|
|
KR102397783B1
(ko)
|
2016-06-01 |
2022-05-12 |
브리스톨-마이어스 스큅 컴퍼니 |
Pd-l1 결합 폴리펩티드에 의한 pet 영상화
|
|
WO2017210335A1
(en)
|
2016-06-01 |
2017-12-07 |
Bristol-Myers Squibb Company |
Imaging methods using 18f-radiolabeled biologics
|
|
MX2018015584A
(es)
|
2016-06-13 |
2019-09-18 |
I Mab |
Anticuerpos anti-pd-l1 y usos de los mismos.
|
|
US20190106494A1
(en)
|
2016-06-13 |
2019-04-11 |
Askgene Pharma Inc. |
PD-L1 Specific Monoclonal Antibodies for Disease Treatment and Diagnosis
|
|
CN109414500B
(zh)
|
2016-06-13 |
2022-02-25 |
奥美药业有限公司 |
治疗和诊断用pd-l1特异性单克隆抗体
|
|
BR112018076260A2
(pt)
|
2016-06-20 |
2019-03-26 |
Kymab Limited |
anticorpo ou fragmento do mesmo que se liga especificamente a hpd-l1, anticorpo biespecífico ou proteína de fusão, uso de um anticorpo ou fragmento, método, composição farmacêutica, método de modulação, método de inibição, método de tratamento, ácido nucleico, vetor, hospedeiro e imunocitocina
|
|
US9567399B1
(en)
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
|
IL321335A
(en)
|
2016-06-29 |
2025-08-01 |
Checkpoint Therapeutics Inc |
PD-L1-specific antibodies and methods of using them
|
|
SG11201900138TA
(en)
|
2016-07-07 |
2019-02-27 |
Iovance Biotherapeutics Inc |
Programmed death 1 ligand 1 (pd-l1) binding proteins and methods of use thereof
|
|
CN106243223B
(zh)
|
2016-07-28 |
2019-03-05 |
北京百特美博生物科技有限公司 |
抗人pdl1抗体及其用途
|
|
US10919966B2
(en)
|
2016-08-05 |
2021-02-16 |
Y-Biologics Inc. |
Antibody to programmed death-ligand 1 (PD-L1) and use thereof
|
|
CN106977602B
(zh)
|
2016-08-23 |
2018-09-25 |
中山康方生物医药有限公司 |
一种抗pd1单克隆抗体、其药物组合物及其用途
|
|
JP2019529437A
(ja)
|
2016-09-20 |
2019-10-17 |
メディミューン，エルエルシー |
抗ｐｄ−ｌ１抗体単独療法に対する固形腫瘍の奏効性を特徴付けるための組成物および方法
|
|
AU2017329780B2
(en)
|
2016-09-20 |
2024-11-14 |
Merck Patent Gmbh |
Diagnostic anti-PD-L1 antibody and use thereof
|
|
EP3522923A1
(en)
|
2016-10-06 |
2019-08-14 |
Pfizer Inc |
Dosing regimen of avelumab for the treatment of cancer
|
|
CN106478819B
(zh)
|
2016-10-27 |
2018-12-07 |
常州费洛斯药业科技有限公司 |
一种针对pd-l1的单克隆抗体或抗体片段
|
|
RU2770590C2
(ru)
|
2016-10-30 |
2022-04-18 |
Шанхай Хенлиус Байотек, Инк. |
Антитела против pd-l1 и их варианты
|
|
EP3538142A4
(en)
|
2016-11-11 |
2020-07-01 |
Medimmune, LLC |
ANTI-PD-L1 AND ANTI-CTLA-4 ANTIBODIES FOR THE TREATMENT OF NON-SMALL CELL LUNG CANCER
|
|
EP3548515A1
(en)
|
2016-12-01 |
2019-10-09 |
Regeneron Pharmaceuticals, Inc. |
Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging
|
|
BR112019011370A2
(pt)
|
2016-12-01 |
2019-10-15 |
Glaxosmithkline Ip Dev Ltd |
terapia de combinação
|
|
US20200024352A1
(en)
|
2016-12-08 |
2020-01-23 |
Eli Lilly And Company |
Anti-tim-3 antibodies for combination with anti-pd-l1 antibodies
|
|
US11273155B2
(en)
|
2016-12-12 |
2022-03-15 |
Daiichi Sankyo Company, Limited |
Combination of antibody-drug conjugate and immune checkpoint inhibitor
|
|
KR20190095921A
(ko)
|
2016-12-12 |
2019-08-16 |
제넨테크, 인크. |
항-pd-l1 항체 및 안티안드로겐을 사용하여 암을 치료하는 방법
|
|
CN106978400A
(zh)
|
2016-12-13 |
2017-07-25 |
无锡傲锐东源生物科技有限公司 |
抗pd‑l1蛋白单克隆抗体及其用途
|
|
WO2018115859A1
(en)
|
2016-12-20 |
2018-06-28 |
Kymab Limited |
Multispecific antibody with combination therapy for immuno-oncology
|
|
JP7304287B2
(ja)
|
2016-12-22 |
2023-07-06 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
抗ｐｄ－ｌ１／ｐｄ１治療の不成功後の、抗ｐｄ－ｌ１抗体との組み合わせでの抗ｃｓｆ－１ｒ抗体を用いた腫瘍の治療
|
|
RU2766582C2
(ru)
|
2016-12-23 |
2022-03-15 |
Ремд Биотерапьютикс, Инк. |
Иммунотерапия с применением антител, связывающих лиганд 1 белка программируемой смерти клеток (PD-L1)
|
|
CN109071656B
(zh)
|
2017-01-05 |
2021-05-18 |
璟尚生物制药公司 |
检查点调节物拮抗剂
|
|
JP7252526B2
(ja)
|
2017-01-23 |
2023-04-05 |
スチョー アルファマブ カンパニー リミテッド |
Ｐｄ－ｌ１結合ポリペプチド又は化合物
|
|
CN106699891B
(zh)
|
2017-01-25 |
2019-04-09 |
北京天广实生物技术股份有限公司 |
一种抗pd-l1抗体、其药物组合物及其用途
|
|
CA3052652A1
(en)
|
2017-02-16 |
2018-08-23 |
John KURLAND |
Anti-pd-l1 antibody treatment of bladder cancer
|
|
CN110662764B
(zh)
|
2017-02-16 |
2023-08-22 |
湘潭腾华生物科技有限公司 |
抗程序性死亡配体1(pd-l1)抗体及其治疗用途
|
|
CN108456251A
(zh)
|
2017-02-21 |
2018-08-28 |
上海君实生物医药科技股份有限公司 |
抗pd-l1抗体及其应用
|
|
CN116836285A
(zh)
|
2017-03-09 |
2023-10-03 |
健玛保 |
针对pd-l1的抗体
|
|
LT3596116T
(lt)
|
2017-03-16 |
2023-11-10 |
Alpine Immune Sciences, Inc. |
Imunomoduliacinių baltymų pd-l1 variantai ir jų naudojimo būdai
|
|
WO2018175279A2
(en)
|
2017-03-20 |
2018-09-27 |
The General Hospital Corporation |
MITIGATING Fc-Fc RECEPTOR INTERACTIONS IN CANCER IMMUNOTHERAPY
|
|
CA3057758A1
(en)
|
2017-03-29 |
2018-10-04 |
Glycotope Gmbh |
Pd-l1 and ta-muc1 antibodies
|
|
WO2018178123A1
(en)
|
2017-03-29 |
2018-10-04 |
Glycotope Gmbh |
BISPECIFIC MUC-1 x PD-L1 ANTIBODIES
|
|
IL269718B2
(en)
|
2017-03-30 |
2024-10-01 |
Merck Patent Gmbh |
Combination of an anti-pd-l1 antibody and a dna-pk inhibitor for the treatment of cancer
|
|
RU2665790C1
(ru)
|
2017-04-17 |
2018-09-04 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело к pd-l1
|
|
EP3630838A1
(en)
*
|
2017-06-01 |
2020-04-08 |
CytomX Therapeutics, Inc. |
Activatable anti-pdl1 antibodies, and methods of use thereof
|
|
CN107973854B
(zh)
|
2017-12-11 |
2021-05-04 |
苏州银河生物医药有限公司 |
Pdl1单克隆抗体及其应用
|
|
CN108250296B
(zh)
|
2018-01-17 |
2020-07-07 |
长春金赛药业有限责任公司 |
全人源抗人pd-l1单克隆抗体及其应用
|
|
CN108276492B
(zh)
|
2018-01-31 |
2021-12-14 |
中国药科大学 |
抗pd－l1单克隆抗体及其应用
|