JP2020510617A5 - - Google Patents
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- Publication number
- JP2020510617A5 JP2020510617A5 JP2019529473A JP2019529473A JP2020510617A5 JP 2020510617 A5 JP2020510617 A5 JP 2020510617A5 JP 2019529473 A JP2019529473 A JP 2019529473A JP 2019529473 A JP2019529473 A JP 2019529473A JP 2020510617 A5 JP2020510617 A5 JP 2020510617A5
- Authority
- JP
- Japan
- Prior art keywords
- benzyl
- pyrazine
- phenyl
- oxo
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662428997P | 2016-12-01 | 2016-12-01 | |
| US62/428,997 | 2016-12-01 | ||
| US201762477512P | 2017-03-28 | 2017-03-28 | |
| US62/477,512 | 2017-03-28 | ||
| PCT/US2017/064229 WO2018102693A1 (en) | 2016-12-01 | 2017-12-01 | Cell impermeable coelenterazine analogues |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510617A JP2020510617A (ja) | 2020-04-09 |
| JP2020510617A5 true JP2020510617A5 (enExample) | 2021-01-21 |
| JP7139330B2 JP7139330B2 (ja) | 2022-09-20 |
Family
ID=60972321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529473A Active JP7139330B2 (ja) | 2016-12-01 | 2017-12-01 | 細胞不透過性セレンテラジンアナログ |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10577370B2 (enExample) |
| EP (2) | EP3548492B1 (enExample) |
| JP (1) | JP7139330B2 (enExample) |
| DK (1) | DK3548492T5 (enExample) |
| WO (1) | WO2018102693A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3548492B1 (en) * | 2016-12-01 | 2023-07-05 | Promega Corporation | Cell impermeable coelenterazine analogues |
| JP7036343B2 (ja) * | 2017-03-28 | 2022-03-15 | 国立大学法人電気通信大学 | 新規セレンテラジン誘導体 |
| EP3788048A1 (en) * | 2018-05-01 | 2021-03-10 | Promega Corporation | Coelenterazine compounds as nanoluc suicide substrates |
| JP7653351B2 (ja) * | 2018-08-23 | 2025-03-28 | プロメガ コーポレイション | セレンテラジン類似体 |
| IL318819A (en) | 2018-10-03 | 2025-04-01 | Promega Corp | Compounds and methods for stabilizing cholinetyrazine and its derivatives |
| CN111116594B (zh) * | 2019-12-03 | 2021-05-28 | 山东大学 | 一种C-6位改造NanoLuc类型类似物及其制备方法与应用 |
| KR102940072B1 (ko) * | 2022-01-10 | 2026-03-17 | 주식회사 엘지화학 | 환상 술폰산에스테르 유도체 화합물의 제조방법 |
| CN116082185B (zh) * | 2023-04-06 | 2023-07-21 | 佛山职业技术学院 | 虫酰肼类半抗原、抗原、抗体、检测装置及其制备与应用 |
| WO2026128753A2 (en) | 2024-12-12 | 2026-06-18 | Juno Therapeutics, Inc. | Methods for assessing cell proliferation of cell compositions |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7268229B2 (en) | 2001-11-02 | 2007-09-11 | Promega Corporation | Compounds to co-localize luminophores with luminescent proteins |
| US8883486B2 (en) | 2004-05-04 | 2014-11-11 | Universite De Montreal | Arrestin biosensor |
| US20080248511A1 (en) | 2007-03-26 | 2008-10-09 | Promega Corporation | Methods to quench light from optical reactions |
| ES2795287T3 (es) | 2009-05-01 | 2020-11-23 | Promega Corp | Luciferasas de Oplophorus sintéticas con mayor emisión de luz |
| CA2815381C (en) | 2010-11-02 | 2019-03-19 | Promega Corporation | Coelenterazine derivatives and methods of using same |
| CN103443121B (zh) * | 2010-11-02 | 2016-04-20 | 普罗梅加公司 | 新型腔肠素底物及其使用方法 |
| US9273343B2 (en) | 2011-09-02 | 2016-03-01 | Promega Corporation | Compounds and methods for assaying redox state of metabolically active cells and methods for measuring NAD(P)/NAD(P)H |
| WO2013078244A1 (en) | 2011-11-21 | 2013-05-30 | Promega Corporation | Carboxy x rhodamine analogs |
| CN104395306B (zh) * | 2012-03-02 | 2019-04-23 | 皮尔斯生物科技有限公司 | 作为生物分子的标记染料的吲哚衍生物 |
| US9790537B2 (en) | 2014-01-29 | 2017-10-17 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| EP3099691B1 (en) | 2014-01-29 | 2019-11-20 | Promega Corporation | Pro-substrates for live cell applications |
| EP3313846B1 (en) | 2015-06-25 | 2020-05-06 | Promega Corporation | Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases |
| JP7092677B2 (ja) | 2016-02-15 | 2022-06-28 | プロメガ コーポレイション | セレンテラジン類似体 |
| CN105968114B (zh) * | 2016-05-27 | 2018-11-09 | 山东大学 | 一种腔肠素类似物及其制备方法与应用 |
| JP7212612B2 (ja) * | 2016-07-28 | 2023-01-25 | プロメガ コーポレイション | セレンテラジン類縁体 |
| JP7200102B2 (ja) * | 2016-11-01 | 2023-01-06 | プロメガ コーポレイション | エネルギー受容体に係留されたセレンテラジン類縁体 |
| EP3548492B1 (en) * | 2016-12-01 | 2023-07-05 | Promega Corporation | Cell impermeable coelenterazine analogues |
-
2017
- 2017-12-01 EP EP17829356.9A patent/EP3548492B1/en active Active
- 2017-12-01 WO PCT/US2017/064229 patent/WO2018102693A1/en not_active Ceased
- 2017-12-01 JP JP2019529473A patent/JP7139330B2/ja active Active
- 2017-12-01 US US15/829,262 patent/US10577370B2/en active Active
- 2017-12-01 EP EP23175129.8A patent/EP4279490A3/en active Pending
- 2017-12-01 DK DK17829356.9T patent/DK3548492T5/da active
-
2019
- 2019-12-23 US US16/725,602 patent/US11192894B2/en active Active
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