JP2016529235A5 - - Google Patents
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- JP2016529235A5 JP2016529235A5 JP2016526992A JP2016526992A JP2016529235A5 JP 2016529235 A5 JP2016529235 A5 JP 2016529235A5 JP 2016526992 A JP2016526992 A JP 2016526992A JP 2016526992 A JP2016526992 A JP 2016526992A JP 2016529235 A5 JP2016529235 A5 JP 2016529235A5
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- JP
- Japan
- Prior art keywords
- optionally
- amino
- group
- alkyl
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361846787P | 2013-07-16 | 2013-07-16 | |
| US61/846,787 | 2013-07-16 | ||
| PCT/US2014/046203 WO2015009545A1 (en) | 2013-07-16 | 2014-07-10 | Derivatives of n-urea substituted amino acids as formyl peptide receptor modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016529235A JP2016529235A (ja) | 2016-09-23 |
| JP2016529235A5 true JP2016529235A5 (enExample) | 2017-08-17 |
| JP6653253B2 JP6653253B2 (ja) | 2020-02-26 |
Family
ID=51230227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016526992A Expired - Fee Related JP6653253B2 (ja) | 2013-07-16 | 2014-07-10 | ホルミルペプチド受容体モジュレーターとしてのｎ−尿素置換アミノ酸の誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9428549B2 (enExample) |
| EP (1) | EP3022174B1 (enExample) |
| JP (1) | JP6653253B2 (enExample) |
| KR (1) | KR102313757B1 (enExample) |
| CN (1) | CN105377814B (enExample) |
| AU (1) | AU2014290618B2 (enExample) |
| CA (1) | CA2917811C (enExample) |
| DK (1) | DK3022174T3 (enExample) |
| ES (1) | ES2708571T3 (enExample) |
| RU (1) | RU2696581C2 (enExample) |
| WO (1) | WO2015009545A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5982001B2 (ja) | 2011-10-26 | 2016-08-31 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体モジュレーターとしてのｎ−尿素置換アミノ酸のアミド誘導体 |
| WO2014138046A1 (en) | 2013-03-06 | 2014-09-12 | Allergan, Inc. | Use of agonists of formyl peptide receptor 2 for treating dermatological diseases |
| JP6496728B2 (ja) | 2013-11-21 | 2019-04-03 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ホルミルペプチド受容体の調節因子としてのカルバミン酸フェニル誘導体 |
| NZ720508A (en) | 2013-11-28 | 2019-03-29 | Kyorin Seiyaku Kk | Urea derivative or pharmacologically acceptable salt thereof |
| US9663457B2 (en) | 2014-04-09 | 2017-05-30 | Allergan, Inc. | Carbamoyl hydrazine derivatives as formyl peptide modulators |
| BR112016027133A8 (pt) | 2014-05-21 | 2021-06-29 | Allergan Inc | derivados de imidazol como moduladores do receptor de formil peptídeo, composição farmacêutica e uso |
| EP3303284B1 (en) | 2015-05-27 | 2020-04-08 | Kyorin Pharmaceutical Co., Ltd. | Urea derivative or pharmacologically acceptable salt thereof |
| EA201792382A1 (ru) | 2015-05-27 | 2018-04-30 | Киорин Фармасютикал Ко., Лтд. | Производное мочевины или его фармакологически приемлемая соль |
| JP6900365B2 (ja) * | 2015-08-05 | 2021-07-07 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ホルミルペプチド受容体１（ｆｐｒ１）選択的アゴニストとしてのフェニル尿素類似体 |
| AU2019232704B2 (en) | 2018-03-05 | 2024-03-21 | Bristol-Myers Squibb Company | Phenylpyrrolidinone formyl peptide 2 receptor agonists |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2533210A1 (fr) | 1982-09-17 | 1984-03-23 | Lyon I Universite Claude | Edulcorants de synthese |
| US5284828A (en) * | 1990-05-14 | 1994-02-08 | Fujisawa Pharmaceutical Co. Ltd. | Peptide compound and its preparation |
| JP3387948B2 (ja) * | 1992-12-04 | 2003-03-17 | 富山化学工業株式会社 | 新規なフェニルアラニン誘導体またはその塩 |
| US20030009022A1 (en) * | 1993-03-31 | 2003-01-09 | Cadus Pharmaceutical Corporation | Methods and compositions for identifying receptor effectors |
| JP2968842B2 (ja) * | 1994-02-09 | 1999-11-02 | 塩野義製薬株式会社 | カルバモイルメチルウレア誘導体 |
| RU2134684C1 (ru) * | 1994-02-09 | 1999-08-20 | Сионоги Энд Ко., Лтд. | Производные карбамоилмочевины и фармацевтическая композиция |
| US6423689B1 (en) * | 1997-12-22 | 2002-07-23 | Warner-Lambert Company | Peptidyl calcium channel blockers |
| AU4572999A (en) * | 1998-06-18 | 2000-01-05 | Sepracor, Inc. | Tetrapeptides, analogs and peptidomimetics which bind selectively mammalian opioid receptors |
| AU2003214249A1 (en) * | 2002-04-03 | 2003-10-13 | Bayer Aktiengesellschaft | Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1) |
| KR20060130064A (ko) * | 2003-11-07 | 2006-12-18 | 아카디아 파마슈티칼스 인코포레이티드 | 통증 및 염증 치료에 효과적인 화합물을 동정하기 위한도구로서의 리폭신 수용체, ｆｐｒｌ1의 용도 |
| NZ597122A (en) * | 2009-05-18 | 2013-06-28 | Actelion Pharmaceuticals Ltd | Bridged spiro [2.4] heptane derivatives as alx receptor and/or fprl2 agonists |
| CA2819457A1 (en) * | 2010-12-03 | 2012-06-07 | Allergan, Inc. | Pharmaceutical compositions comprising 3,4-dihydroisoquinolin-2(1h)-yl-3-phenylurea derivatives having formyl peptide receptor like-1 (fprl-1) agonist or antagonist activity |
| JP5982001B2 (ja) * | 2011-10-26 | 2016-08-31 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体モジュレーターとしてのｎ−尿素置換アミノ酸のアミド誘導体 |
| US8541577B2 (en) * | 2011-11-10 | 2013-09-24 | Allergan, Inc. | Aryl urea derivatives as N-formyl peptide receptors like-1 (FPRL-1) receptor modulators |
| US8735622B2 (en) * | 2011-11-30 | 2014-05-27 | The Regents Of The University Of Colorado, A Body Corporate | Histone demethylase inhibitors and methods for using the same |
| CA2898301C (en) * | 2013-03-06 | 2021-11-16 | Allergan, Inc. | Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases |
| WO2014138046A1 (en) * | 2013-03-06 | 2014-09-12 | Allergan, Inc. | Use of agonists of formyl peptide receptor 2 for treating dermatological diseases |
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2014
- 2014-07-10 WO PCT/US2014/046203 patent/WO2015009545A1/en not_active Ceased
- 2014-07-10 AU AU2014290618A patent/AU2014290618B2/en not_active Ceased
- 2014-07-10 DK DK14744725.4T patent/DK3022174T3/da active
- 2014-07-10 JP JP2016526992A patent/JP6653253B2/ja not_active Expired - Fee Related
- 2014-07-10 RU RU2016104844A patent/RU2696581C2/ru active
- 2014-07-10 US US14/328,540 patent/US9428549B2/en active Active
- 2014-07-10 KR KR1020167003770A patent/KR102313757B1/ko not_active Expired - Fee Related
- 2014-07-10 ES ES14744725T patent/ES2708571T3/es active Active
- 2014-07-10 EP EP14744725.4A patent/EP3022174B1/en active Active
- 2014-07-10 CA CA2917811A patent/CA2917811C/en active Active
- 2014-07-10 CN CN201480040132.5A patent/CN105377814B/zh not_active Expired - Fee Related