|
US20100047338A1
(en)
|
2008-03-14 |
2010-02-25 |
Angela Brodie |
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
|
|
EP2211615A4
(en)
*
|
2007-10-22 |
2010-10-13 |
Glaxosmithkline Llc |
PYRIDOSULFONAMIDE DERIVATIVES AS PI3 KINASE INHIBITORS
|
|
ES2474147T3
(es)
|
2008-05-30 |
2014-07-08 |
Amgen, Inc |
Inhibidores de PI3 cinasa
|
|
BRPI0917540A2
(pt)
|
2008-08-05 |
2015-11-17 |
Daiichi Sankyo Co Ltd |
composto, sal farmacologicamente aceitavél, composição farmacêutica, e, uso de um composto ou sal farmacologicamente aceitável
|
|
BRPI1004899B8
(pt)
|
2009-01-08 |
2021-05-25 |
Curis Inc |
composto inibidor de fosfoinositida 3-quinase, composição farmacêutica e uso de um composto
|
|
WO2010091306A1
(en)
|
2009-02-05 |
2010-08-12 |
Tokai Pharmaceuticals |
Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens
|
|
CN102480966B
(zh)
*
|
2009-06-12 |
2015-09-16 |
达娜-法勃肿瘤研究所公司 |
融合的杂环化合物及其用途
|
|
JP5819831B2
(ja)
|
2009-08-17 |
2015-11-24 |
インテリカイン， エルエルシー |
複素環式化合物およびそれらの使用
|
|
US9180127B2
(en)
|
2009-12-29 |
2015-11-10 |
Dana-Farber Cancer Institute, Inc. |
Type II Raf kinase inhibitors
|
|
US20110319405A1
(en)
*
|
2010-06-28 |
2011-12-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Treatment and prevention of diffuse parenchymal lung disease by selective active-site mTOR inhibitors
|
|
UY33337A
(es)
|
2010-10-18 |
2011-10-31 |
Respivert Ltd |
DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS
|
|
US9127000B2
(en)
|
2011-02-23 |
2015-09-08 |
Intellikine, LLC. |
Heterocyclic compounds and uses thereof
|
|
AU2012236367B2
(en)
|
2011-04-01 |
2014-10-09 |
Curis, Inc. |
Phosphoinositide 3-kinase inhibitor with a zinc binding moiety
|
|
MX351818B
(es)
*
|
2011-09-30 |
2017-10-30 |
Kineta Inc |
Compuestos antivirales.
|
|
CN104204804B
(zh)
*
|
2011-11-11 |
2016-09-28 |
因特利凯有限责任公司 |
激酶抑制剂的组合及其用途
|
|
US9382239B2
(en)
|
2011-11-17 |
2016-07-05 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of c-Jun-N-terminal kinase (JNK)
|
|
WO2013142245A1
(en)
*
|
2012-03-23 |
2013-09-26 |
Memorial Sloan-Kettering Cancer Center |
Potentiating antibody-induced complement-mediated cytotoxicity via pi3k inhibition
|
|
AU2013318205B2
(en)
*
|
2012-09-20 |
2016-05-19 |
Novartis Ag |
Pharmaceutical combination comprising a phosphatidylinositol 3-kinase inhibitor|and an aromatase inhibitor
|
|
US10112927B2
(en)
|
2012-10-18 |
2018-10-30 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (CDK7)
|
|
US10000483B2
(en)
|
2012-10-19 |
2018-06-19 |
Dana-Farber Cancer Institute, Inc. |
Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof
|
|
US9758522B2
(en)
|
2012-10-19 |
2017-09-12 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged small molecules as inducers of protein degradation
|
|
US9073946B2
(en)
|
2013-01-15 |
2015-07-07 |
Kineta, Inc. |
Anti-viral compounds
|
|
WO2014158649A1
(en)
*
|
2013-03-13 |
2014-10-02 |
Dow Agrosciences Llc |
Preparation of 1,3-(substituted-diaryl)-1,2,4-triazoles
|
|
US20140275564A1
(en)
*
|
2013-03-13 |
2014-09-18 |
Dow Agrosciences Llc |
Process for the preparation of certain triaryl rhamnose carbamates
|
|
AU2014236135A1
(en)
|
2013-03-14 |
2015-09-10 |
Thomas Jefferson University |
Androgen receptor down-regulating agents and uses thereof
|
|
KR20160058774A
(ko)
|
2013-08-12 |
2016-05-25 |
토카이 파마슈티컬, 아이엔씨. |
안드로겐-표적 치료제를 이용하는 종양 질환 치료를 위한 바이오마커
|
|
US9745321B2
(en)
|
2013-09-30 |
2017-08-29 |
Shanghai Yingli Pharmaceutical Co., Ltd |
Fused pyrimidine compound, intermediate, preparation method therefor, and composition and application thereof
|
|
EP3057955B1
(en)
|
2013-10-18 |
2018-04-11 |
Syros Pharmaceuticals, Inc. |
Heteroaromatic compounds useful for the treatment of prolferative diseases
|
|
CN105849099B
(zh)
|
2013-10-18 |
2020-01-17 |
达纳-法伯癌症研究所股份有限公司 |
周期蛋白依赖性激酶7(cdk7)的多环抑制剂
|
|
SMT202400142T1
(it)
|
2014-01-13 |
2024-05-14 |
Aurigene Oncology Ltd |
Enantiomeri (r) e (s) di n-(5-(3-idrossipirrolidin-1-il)-2-morfolinoossazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)ossazolo-carbossammide in qualità di inibitori di irak4 per il trattamento di un cancro
|
|
US9802960B2
(en)
|
2014-01-14 |
2017-10-31 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
US10202373B2
(en)
|
2014-01-14 |
2019-02-12 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
AU2015237200A1
(en)
|
2014-03-27 |
2016-10-06 |
The Brigham And Women's Hospital, Inc. |
Metabolically-activated drug conjugates to overcome resistance in cancer therapy
|
|
US9862688B2
(en)
|
2014-04-23 |
2018-01-09 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged janus kinase inhibitors and uses thereof
|
|
US10017477B2
(en)
|
2014-04-23 |
2018-07-10 |
Dana-Farber Cancer Institute, Inc. |
Janus kinase inhibitors and uses thereof
|
|
CN105130973B
(zh)
*
|
2014-05-26 |
2018-05-01 |
海南国瑞堂中药制药有限公司 |
5-吡啶基-2-氨基-苯并[d]噁唑衍生物及其制备方法和用途
|
|
JP2017518307A
(ja)
|
2014-06-02 |
2017-07-06 |
チルドレンズ メディカル センター コーポレーション |
免疫調節のための方法および組成物
|
|
WO2016105528A2
(en)
|
2014-12-23 |
2016-06-30 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (cdk7)
|
|
CA2978518C
(en)
|
2015-03-27 |
2023-11-21 |
Nathanael S. Gray |
Inhibitors of cyclin-dependent kinases
|
|
WO2016201370A1
(en)
|
2015-06-12 |
2016-12-15 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
|
WO2017044858A2
(en)
|
2015-09-09 |
2017-03-16 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
|
US11116754B2
(en)
|
2015-11-13 |
2021-09-14 |
The Trustees Of Columbia University In The City Of New York |
Inhibition of TOR complex 2 increases immunity against bacterial infection
|
|
WO2017156350A1
(en)
|
2016-03-09 |
2017-09-14 |
K-Gen, Inc. |
Methods of cancer treatment
|
|
WO2018017435A1
(en)
*
|
2016-07-22 |
2018-01-25 |
Accro Bioscience Inc. |
Heteroaryl compounds as inhibitors of necrosis, composition and application thereof
|
|
CN107641118B
(zh)
*
|
2016-07-22 |
2020-11-06 |
爱科诺生物医药股份有限公司 |
具有细胞坏死抑制活性的化合物及其组合物和应用
|
|
EP4252853A3
(en)
*
|
2017-03-31 |
2023-12-13 |
Aurigene Oncology Limited |
Compounds and compositions for treating hematological disorders
|
|
WO2018237370A1
(en)
*
|
2017-06-23 |
2018-12-27 |
Accro Bioscience Inc. |
Heteroaryl compounds as inhibitors of necrosis, composition and method using the same
|
|
CN109111464B
(zh)
*
|
2017-06-23 |
2021-02-26 |
爱科诺生物医药股份有限公司 |
一种具有细胞坏死抑制活性的杂环化合物
|
|
AU2018289581C1
(en)
*
|
2017-06-23 |
2025-01-30 |
VelosBio Inc. |
ROR1 antibody immunoconjugates
|
|
MX2020003593A
(es)
|
2017-10-02 |
2020-07-22 |
1St Biotherapeutics Inc |
Compuestos de benzotiazol y metodos para usar los mismos para tratar trastornos neurodegenerativos.
|
|
CN113194752A
(zh)
|
2018-06-01 |
2021-07-30 |
康奈尔大学 |
Pi3k相关疾病或病症的组合疗法
|
|
US20210252175A1
(en)
|
2018-06-08 |
2021-08-19 |
Ac Immune Sa |
Novel compounds for diagnosis
|
|
CN112367991A
(zh)
|
2018-06-25 |
2021-02-12 |
达纳-法伯癌症研究所股份有限公司 |
Taire家族激酶抑制剂及其用途
|
|
EA202190748A1
(ru)
|
2018-09-11 |
2021-07-22 |
Кьюрис Инк. |
Комбинированная терапия ингибитором фосфоинозитид-3-киназы с цинк-связывающей группировкой
|
|
CN109320511A
(zh)
*
|
2018-10-26 |
2019-02-12 |
广安凯特制药有限公司 |
一种高纯度帕博西尼中间体产品及其制备方法
|
|
WO2020140098A1
(en)
|
2018-12-28 |
2020-07-02 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 and uses thereof
|
|
IL285708B2
(en)
|
2019-02-22 |
2025-02-01 |
1St Biotherapeutics Inc |
Imidazopyridinyl compounds and their uses in the treatment of degenerative neurological diseases
|
|
JP7456641B2
(ja)
*
|
2019-03-07 |
2024-03-27 |
ファースト・バイオセラピューティクス・インコーポレイテッド |
Ｐｅｔ放射性トレーサーとしての［１８ｆ］標識ベンゾチアゾール誘導体
|
|
US10385046B1
(en)
|
2019-03-19 |
2019-08-20 |
1ST Biotherapeutics, Inc. |
Processes for preparing benzothiazol compounds and methods of using the same for treating neurodegenerative disorders
|
|
WO2020194260A1
(en)
*
|
2019-03-28 |
2020-10-01 |
1ST Biotherapeutics, Inc. |
Pharmaceutical salts of benzothiazol compounds, polymorphs and methods for preparation thereof
|
|
CN110256466A
(zh)
*
|
2019-07-31 |
2019-09-20 |
昆山迪安医学检验实验室有限公司 |
一种噻唑[5,4-b]-吡啶基生物活性化合物的制备方法及其抗肿瘤活性的检测
|
|
JP7769388B2
(ja)
|
2019-12-12 |
2025-11-13 |
ティン セラピューティクス，インコーポレイテッド |
聴覚損失の予防及び治療のための組成物及び方法
|
|
WO2021242955A1
(en)
*
|
2020-05-28 |
2021-12-02 |
Senda Biosciences, Inc. |
Fused azole heterocycles as ahr antagonists
|
|
EP4200269A1
(en)
*
|
2020-08-21 |
2023-06-28 |
1st Biotherapeutics, Inc. |
[ 18F]-LABELED IMIDAZOPYRIDINE DERIVATIVES AS PET RADIOTRACER

|
|
WO2022038574A1
(en)
*
|
2020-08-21 |
2022-02-24 |
1ST Biotherapeutics, Inc. |
Compounds for prevention or treatment of neurodegenerative disorders
|
|
EP4217358A4
(en)
|
2020-09-28 |
2025-01-08 |
1st Biotherapeutics, Inc. |
INDAZOLES AS INHIBITORS OF HEMATOPOETIC PRECURSOR KINASE 1 (HPK1) AND METHODS OF USE THEREOF
|
|
PH12023552792A1
(en)
|
2021-04-08 |
2024-05-20 |
Curis Inc |
Combination therapies for the treatment of cancer
|
|
US20240382628A1
(en)
|
2021-07-15 |
2024-11-21 |
President And Fellows Of Harvard College |
Compositions and methods relating to cells with adhered particles
|
|
CZ310416B6
(cs)
*
|
2023-12-15 |
2025-05-28 |
Univerzita Hradec Králové |
1-(3-Chlor-4-hydroxyfenyl)-3-(6-((trifluormethyl)thio)benzo[d]thiazol-2-yl)močovina pro použití pro léčbu rakoviny
|