|
JP2011500823A
(ja)
*
|
2007-10-22 |
2011-01-06 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
Pi3キナーゼ阻害物質としてのピリドスルホンアミド誘導体
|
|
US20100048524A1
(en)
|
2008-03-14 |
2010-02-25 |
Angela Brodie |
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
|
|
JP5599783B2
(ja)
|
2008-05-30 |
2014-10-01 |
アムジエン・インコーポレーテツド |
Pi3キナーゼの阻害薬
|
|
DK2308877T3
(da)
|
2008-08-05 |
2014-04-22 |
Daiichi Sankyo Co Ltd |
Imidazopyridin-2-on-derivater
|
|
PT2385832E
(pt)
|
2009-01-08 |
2015-11-02 |
Curis Inc |
Inibidores de fosfoinoritide 3-quinase com uma fração de ligação ao zinco
|
|
EP2393827B1
(en)
|
2009-02-05 |
2015-10-07 |
Tokai Pharmaceuticals, Inc. |
Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens
|
|
US8765747B2
(en)
*
|
2009-06-12 |
2014-07-01 |
Dana-Farber Cancer Institute, Inc. |
Fused 2-aminothiazole compounds
|
|
UA111579C2
(uk)
|
2009-08-17 |
2016-05-25 |
Інтеллікіне Ллк |
ГЕТЕРОЦИКЛІЧНІ ПОХІДНІ 2-АМІНОБЕНЗО[d]ОКСАЗОЛУ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ НА ЇХ ОСНОВІ ТА ЇХ ЗАСТОСУВАННЯ ДЛЯ ЛІКУВАННЯ ЗАХВОРЮВАННЯ, ПОВ'АНОГО З РІ3-КІНАЗОЮ
|
|
EP2937345B1
(en)
|
2009-12-29 |
2018-03-21 |
Dana-Farber Cancer Institute, Inc. |
Type ii raf kinase inhibitors
|
|
US20110319405A1
(en)
*
|
2010-06-28 |
2011-12-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Treatment and prevention of diffuse parenchymal lung disease by selective active-site mTOR inhibitors
|
|
UY33337A
(es)
|
2010-10-18 |
2011-10-31 |
Respivert Ltd |
DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS
|
|
WO2012116237A2
(en)
|
2011-02-23 |
2012-08-30 |
Intellikine, Llc |
Heterocyclic compounds and uses thereof
|
|
PT3111938T
(pt)
|
2011-04-01 |
2019-07-10 |
Curis Inc |
Inibidores de fosfoinoritide 3-quinase com uma fração de ligação ao zinco
|
|
AU2012315953A1
(en)
|
2011-09-30 |
2014-04-03 |
Kineta, Inc. |
Anti-viral compounds
|
|
WO2013071264A1
(en)
*
|
2011-11-11 |
2013-05-16 |
Intellikine, Llc |
Combination of kinase inhibitors and uses thereof
|
|
JP6106685B2
(ja)
|
2011-11-17 |
2017-04-05 |
ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド |
C−jun−n−末端キナーゼ(jnk)の阻害剤
|
|
CA2867700A1
(en)
*
|
2012-03-23 |
2013-09-26 |
Memorial Sloan-Kettering Cancer Center |
Potentiating antibody-induced complement-mediated cytotoxicity via pi3k inhibition
|
|
DK2897644T3
(en)
*
|
2012-09-20 |
2018-09-10 |
Novartis Ag |
Pharmaceutical combination comprising a phosphatidylinositol 3-kinase inhibitor and an aromatase inhibitor
|
|
EP2909194A1
(en)
|
2012-10-18 |
2015-08-26 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (cdk7)
|
|
USRE48175E1
(en)
|
2012-10-19 |
2020-08-25 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged small molecules as inducers of protein degradation
|
|
US10000483B2
(en)
|
2012-10-19 |
2018-06-19 |
Dana-Farber Cancer Institute, Inc. |
Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof
|
|
US9073946B2
(en)
*
|
2013-01-15 |
2015-07-07 |
Kineta, Inc. |
Anti-viral compounds
|
|
US20140275560A1
(en)
*
|
2013-03-13 |
2014-09-18 |
Dow Agrosciences Llc |
Preparation of 1,3-(substituted-diaryl)-1,2,4-triazoles and intermediates therefrom
|
|
US20140275564A1
(en)
*
|
2013-03-13 |
2014-09-18 |
Dow Agrosciences Llc |
Process for the preparation of certain triaryl rhamnose carbamates
|
|
CA2904170A1
(en)
|
2013-03-14 |
2014-09-25 |
University Of Maryland, Baltimore |
Androgen receptor down-regulating agents and uses thereof
|
|
KR20160058774A
(ko)
|
2013-08-12 |
2016-05-25 |
토카이 파마슈티컬, 아이엔씨. |
안드로겐-표적 치료제를 이용하는 종양 질환 치료를 위한 바이오마커
|
|
JP6441910B2
(ja)
|
2013-09-30 |
2018-12-19 |
シャンハイ インリ ファーマシューティカル カンパニー リミティド |
縮合ピリミジン化合物、中間体、その調製方法、組成物及び使用
|
|
AU2014337044A1
(en)
|
2013-10-18 |
2016-05-05 |
Dana-Farber Cancer Institute, Inc. |
Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7)
|
|
WO2015058126A1
(en)
|
2013-10-18 |
2015-04-23 |
Syros Pharmaceuticals, Inc. |
Heteroaromatic compounds useful for the treatment of prolferative diseases
|
|
IL311677B2
(en)
|
2014-01-13 |
2025-06-01 |
Aurigene Oncology Ltd |
Bicyclic heterocyclyl derivatives as irak4 inhibitors
|
|
TN2016000270A1
(en)
|
2014-01-14 |
2017-10-06 |
Millennium Pharm Inc |
Heteroaryls and uses thereof.
|
|
WO2015108881A1
(en)
|
2014-01-14 |
2015-07-23 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
CA2943609A1
(en)
|
2014-03-27 |
2015-10-01 |
The Brigham And Women's Hospital, Inc. |
Metabolically-activated drug conjugates to overcome resistance in cancer therapy
|
|
US9862688B2
(en)
|
2014-04-23 |
2018-01-09 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged janus kinase inhibitors and uses thereof
|
|
WO2015164614A1
(en)
|
2014-04-23 |
2015-10-29 |
Dana-Farber Cancer Institute, Inc. |
Janus kinase inhibitors and uses thereof
|
|
CN105130973B
(zh)
*
|
2014-05-26 |
2018-05-01 |
海南国瑞堂中药制药有限公司 |
5-吡啶基-2-氨基-苯并[d]噁唑衍生物及其制备方法和用途
|
|
JP2017518307A
(ja)
|
2014-06-02 |
2017-07-06 |
チルドレンズ メディカル センター コーポレーション |
免疫調節のための方法および組成物
|
|
US10870651B2
(en)
|
2014-12-23 |
2020-12-22 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (CDK7)
|
|
CN107427521B
(zh)
|
2015-03-27 |
2021-08-03 |
达纳-法伯癌症研究所股份有限公司 |
细胞周期蛋白依赖性激酶的抑制剂
|
|
CA2986441A1
(en)
|
2015-06-12 |
2016-12-15 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
|
WO2017044858A2
(en)
|
2015-09-09 |
2017-03-16 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
|
US11116754B2
(en)
|
2015-11-13 |
2021-09-14 |
The Trustees Of Columbia University In The City Of New York |
Inhibition of TOR complex 2 increases immunity against bacterial infection
|
|
US10722484B2
(en)
|
2016-03-09 |
2020-07-28 |
K-Gen, Inc. |
Methods of cancer treatment
|
|
WO2018017435A1
(en)
*
|
2016-07-22 |
2018-01-25 |
Accro Bioscience Inc. |
Heteroaryl compounds as inhibitors of necrosis, composition and application thereof
|
|
CN107641118B
(zh)
*
|
2016-07-22 |
2020-11-06 |
爱科诺生物医药股份有限公司 |
具有细胞坏死抑制活性的化合物及其组合物和应用
|
|
CN120267671A
(zh)
*
|
2017-03-31 |
2025-07-08 |
奥锐金肿瘤有限公司 |
用于治疗血液病的化合物和组合物
|
|
TWI804499B
(zh)
*
|
2017-06-23 |
2023-06-11 |
美商維洛斯生物公司 |
Ror1抗體免疫接合物
|
|
WO2018237370A1
(en)
*
|
2017-06-23 |
2018-12-27 |
Accro Bioscience Inc. |
Heteroaryl compounds as inhibitors of necrosis, composition and method using the same
|
|
CN109111464B
(zh)
*
|
2017-06-23 |
2021-02-26 |
爱科诺生物医药股份有限公司 |
一种具有细胞坏死抑制活性的杂环化合物
|
|
MX2020003593A
(es)
|
2017-10-02 |
2020-07-22 |
1St Biotherapeutics Inc |
Compuestos de benzotiazol y metodos para usar los mismos para tratar trastornos neurodegenerativos.
|
|
EP3801069A4
(en)
|
2018-06-01 |
2022-03-16 |
Cornell University |
COMBINATION THERAPY FOR A PI3K-ASSOCIATED DISEASE OR DISORDER
|
|
WO2019234243A1
(en)
|
2018-06-08 |
2019-12-12 |
Ac Immune Sa |
Novel compounds for diagnosis
|
|
EP3810132A4
(en)
|
2018-06-25 |
2022-06-22 |
Dana-Farber Cancer Institute, Inc. |
TAIRE FAMILY KINASE INHIBITORS AND RELATED USES
|
|
EP3849554B1
(en)
|
2018-09-11 |
2025-01-29 |
Curis, Inc. |
Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety
|
|
CN109320511A
(zh)
*
|
2018-10-26 |
2019-02-12 |
广安凯特制药有限公司 |
一种高纯度帕博西尼中间体产品及其制备方法
|
|
CN113164477A
(zh)
|
2018-12-14 |
2021-07-23 |
达纳-法伯癌症研究所股份有限公司 |
C-jun-n-末端激酶的吡唑并吡啶抑制剂及其用途
|
|
EP3902542A4
(en)
|
2018-12-28 |
2022-09-07 |
Dana-Farber Cancer Institute, Inc. |
CYCLIN DEPENDENT KINASE 7 INHIBITORS AND USES THEREOF
|
|
JP2022521537A
(ja)
|
2019-02-22 |
2022-04-08 |
ファースト・バイオセラピューティクス・インコーポレイテッド |
イミダゾピリジニル化合物及び増殖性障害の処置のためのその使用
|
|
KR20210126146A
(ko)
*
|
2019-03-07 |
2021-10-19 |
주식회사 퍼스트바이오테라퓨틱스 |
Pet 방사선추적자로서의 [18f]-라벨링된 벤조티아졸 유도체
|
|
US10385046B1
(en)
|
2019-03-19 |
2019-08-20 |
1ST Biotherapeutics, Inc. |
Processes for preparing benzothiazol compounds and methods of using the same for treating neurodegenerative disorders
|
|
WO2020194260A1
(en)
*
|
2019-03-28 |
2020-10-01 |
1ST Biotherapeutics, Inc. |
Pharmaceutical salts of benzothiazol compounds, polymorphs and methods for preparation thereof
|
|
CN110256466A
(zh)
*
|
2019-07-31 |
2019-09-20 |
昆山迪安医学检验实验室有限公司 |
一种噻唑[5,4-b]-吡啶基生物活性化合物的制备方法及其抗肿瘤活性的检测
|
|
CN114981298B
(zh)
|
2019-12-12 |
2024-08-20 |
听治疗有限责任公司 |
用于预防和治疗听力损失的组合物和方法
|
|
WO2021236717A1
(en)
|
2020-05-20 |
2021-11-25 |
Senda Biosciences, Inc. |
Fused imidazole derivatives as ahr antagonists
|
|
WO2021242955A1
(en)
*
|
2020-05-28 |
2021-12-02 |
Senda Biosciences, Inc. |
Fused azole heterocycles as ahr antagonists
|
|
WO2022038574A1
(en)
*
|
2020-08-21 |
2022-02-24 |
1ST Biotherapeutics, Inc. |
Compounds for prevention or treatment of neurodegenerative disorders
|
|
US12509458B2
(en)
|
2020-08-21 |
2025-12-30 |
1ST Biotherapeutics, Inc. |
[18F]-labeled imidazopyridine derivatives as PET radiotracer
|
|
WO2022064458A1
(en)
|
2020-09-28 |
2022-03-31 |
1ST Biotherapeutics, Inc. |
Indazoles as hematopoietic progenitor kinase 1 (hpk1) inhibitors and methods of using same
|
|
WO2022120039A2
(en)
*
|
2020-12-02 |
2022-06-09 |
Steven Hoffman |
Compositions and methods for modulating cancer in non-human mammals
|
|
CA3214747A1
(en)
|
2021-04-08 |
2022-10-13 |
Reinhard Von Roemeling |
Combination therapies for the treatment of cancer
|
|
US20240382628A1
(en)
|
2021-07-15 |
2024-11-21 |
President And Fellows Of Harvard College |
Compositions and methods relating to cells with adhered particles
|
|
CZ310416B6
(cs)
*
|
2023-12-15 |
2025-05-28 |
Univerzita Hradec Králové |
1-(3-Chlor-4-hydroxyfenyl)-3-(6-((trifluormethyl)thio)benzo[d]thiazol-2-yl)močovina pro použití pro léčbu rakoviny
|
|
GB202415232D0
(en)
|
2024-10-16 |
2024-11-27 |
Nacamed As |
Composition
|