JP2021523111A5 - - Google Patents
Info
- Publication number
- JP2021523111A5 JP2021523111A5 JP2020561071A JP2020561071A JP2021523111A5 JP 2021523111 A5 JP2021523111 A5 JP 2021523111A5 JP 2020561071 A JP2020561071 A JP 2020561071A JP 2020561071 A JP2020561071 A JP 2020561071A JP 2021523111 A5 JP2021523111 A5 JP 2021523111A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- oplophorus
- oxo
- optionally substituted
- pyrazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862665346P | 2018-05-01 | 2018-05-01 | |
| US62/665,346 | 2018-05-01 | ||
| PCT/US2019/029975 WO2019213119A1 (en) | 2018-05-01 | 2019-04-30 | Coelenterazine compounds as nanoluc suicide substrates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021523111A JP2021523111A (ja) | 2021-09-02 |
| JP2021523111A5 true JP2021523111A5 (enExample) | 2022-05-13 |
| JP7419260B2 JP7419260B2 (ja) | 2024-01-22 |
Family
ID=66530467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020561071A Active JP7419260B2 (ja) | 2018-05-01 | 2019-04-30 | NanoLuc自殺基質としてのセレンテラジン化合物 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US11655247B2 (enExample) |
| EP (1) | EP3788048A1 (enExample) |
| JP (1) | JP7419260B2 (enExample) |
| WO (1) | WO2019213119A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7653351B2 (ja) | 2018-08-23 | 2025-03-28 | プロメガ コーポレイション | セレンテラジン類似体 |
| IL318819A (en) | 2018-10-03 | 2025-04-01 | Promega Corp | Compounds and methods for stabilizing cholinetyrazine and its derivatives |
| KR20230147105A (ko) * | 2021-01-28 | 2023-10-20 | 진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. | 리가제 융합 단백질 및 그 응용 |
| CN120051474A (zh) | 2022-10-14 | 2025-05-27 | 普罗美加公司 | 腔肠素类似物 |
| US20250206747A1 (en) | 2023-12-20 | 2025-06-26 | Promega Corporation | Coelenterazine analogues |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7268229B2 (en) | 2001-11-02 | 2007-09-11 | Promega Corporation | Compounds to co-localize luminophores with luminescent proteins |
| US8883486B2 (en) | 2004-05-04 | 2014-11-11 | Universite De Montreal | Arrestin biosensor |
| US20080248511A1 (en) | 2007-03-26 | 2008-10-09 | Promega Corporation | Methods to quench light from optical reactions |
| ES2795287T3 (es) | 2009-05-01 | 2020-11-23 | Promega Corp | Luciferasas de Oplophorus sintéticas con mayor emisión de luz |
| CN103443121B (zh) * | 2010-11-02 | 2016-04-20 | 普罗梅加公司 | 新型腔肠素底物及其使用方法 |
| CA2815381C (en) | 2010-11-02 | 2019-03-19 | Promega Corporation | Coelenterazine derivatives and methods of using same |
| US9273343B2 (en) | 2011-09-02 | 2016-03-01 | Promega Corporation | Compounds and methods for assaying redox state of metabolically active cells and methods for measuring NAD(P)/NAD(P)H |
| WO2013078244A1 (en) | 2011-11-21 | 2013-05-30 | Promega Corporation | Carboxy x rhodamine analogs |
| CN104395306B (zh) | 2012-03-02 | 2019-04-23 | 皮尔斯生物科技有限公司 | 作为生物分子的标记染料的吲哚衍生物 |
| US9790537B2 (en) | 2014-01-29 | 2017-10-17 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| EP3099691B1 (en) | 2014-01-29 | 2019-11-20 | Promega Corporation | Pro-substrates for live cell applications |
| EP3313846B1 (en) | 2015-06-25 | 2020-05-06 | Promega Corporation | Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases |
| JP7092677B2 (ja) | 2016-02-15 | 2022-06-28 | プロメガ コーポレイション | セレンテラジン類似体 |
| JP7212612B2 (ja) | 2016-07-28 | 2023-01-25 | プロメガ コーポレイション | セレンテラジン類縁体 |
| JP7200102B2 (ja) | 2016-11-01 | 2023-01-06 | プロメガ コーポレイション | エネルギー受容体に係留されたセレンテラジン類縁体 |
| EP3548492B1 (en) * | 2016-12-01 | 2023-07-05 | Promega Corporation | Cell impermeable coelenterazine analogues |
-
2019
- 2019-04-30 EP EP19723958.5A patent/EP3788048A1/en active Pending
- 2019-04-30 WO PCT/US2019/029975 patent/WO2019213119A1/en not_active Ceased
- 2019-04-30 US US16/399,410 patent/US11655247B2/en active Active
- 2019-04-30 JP JP2020561071A patent/JP7419260B2/ja active Active
-
2023
- 2023-04-05 US US18/296,203 patent/US12570654B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230175036A1 (en) | Self-immolative probes for enzyme activity detection | |
| RU2080321C1 (ru) | Азотсодержащие гетероциклические соединения в виде рацемата или отдельных энантиомеров, являющиеся ингибиторами биосинтеза лейкотриена | |
| US12326385B2 (en) | Cell-permeable fluorogenic fluorophores | |
| US12018157B2 (en) | Tunable photoactivatable silicon rhodamine fluorophores | |
| JP2020504754A5 (enExample) | ||
| CN112566986A (zh) | 经硅取代的罗丹明染料和染料缀合物 | |
| US20160047748A1 (en) | Fluorescent probe | |
| Chevalier | The how and why of naphthalimide/heterocycle-fused hybrid dyes: an overview of the latest developments in the quest for dyes with innovative optical properties | |
| JP2535569B2 (ja) | 新規な写真用シアンカプラ―を含有するハロゲン化銀カラ―写真感光材料 | |
| GB2031876A (en) | Colour couplers for use in photographic materials | |
| JP4206381B2 (ja) | パーオキシナイトライト測定用試薬 | |
| Rehse et al. | New 1H‐Pyrazole‐4‐Carboxamides with Antiplatelet Activity | |
| US4910124A (en) | Color image-forming process | |
| BRPI0813550B1 (pt) | Composto derivado fluorescente de poliaminas, seu processo de síntese e seu uso | |
| US20150079622A1 (en) | Modified Nucleic Acid Binding Cyanine Dyes for the Detection of Reactive Oxygen Species | |
| US7977120B2 (en) | Fluorescent sensors for cellular amines | |
| US20230085832A1 (en) | Methods and compositions for assessing cell viability | |
| JPH01557A (ja) | 新規なシアンカプラーを含有するハロゲン化銀カラー写真感光材料 | |
| JPH05209152A (ja) | ゼラチンの硬膜方法、硬膜されたゼラチン組成物及び写真要素 | |
| EP3556762A1 (en) | Novel tunable photoactivatable silicon rhodamine fluorophores | |
| US20240385087A1 (en) | Method for staining mitochondria | |
| JPS63287851A (ja) | カラ−感光材料 | |
| JPH01105251A (ja) | 新規なシアンカプラーを含有するハロゲン化銀カラー写真感光材料 | |
| GB2282605A (en) | Photographic sensitising dyes | |
| JPH02864A (ja) | 画像保存性及びカブリの改良された熱現像感光材料 |