JP2020504754A5 - - Google Patents
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- Publication number
- JP2020504754A5 JP2020504754A5 JP2019535843A JP2019535843A JP2020504754A5 JP 2020504754 A5 JP2020504754 A5 JP 2020504754A5 JP 2019535843 A JP2019535843 A JP 2019535843A JP 2019535843 A JP2019535843 A JP 2019535843A JP 2020504754 A5 JP2020504754 A5 JP 2020504754A5
- Authority
- JP
- Japan
- Prior art keywords
- carboxamide
- group
- amino
- ethyl
- oxoethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- CQUNASYKUVRVAK-UHFFFAOYSA-N CC(CCOCCOCCOCCOCCNC)=O Chemical compound CC(CCOCCOCCOCCOCCNC)=O CQUNASYKUVRVAK-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662439600P | 2016-12-28 | 2016-12-28 | |
| US62/439,600 | 2016-12-28 | ||
| PCT/US2017/068686 WO2018125992A1 (en) | 2016-12-28 | 2017-12-28 | Functionalized nanoluc inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020504754A JP2020504754A (ja) | 2020-02-13 |
| JP2020504754A5 true JP2020504754A5 (enExample) | 2021-02-12 |
| JP7161475B2 JP7161475B2 (ja) | 2022-10-26 |
Family
ID=61007855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019535843A Active JP7161475B2 (ja) | 2016-12-28 | 2017-12-28 | 官能化ｎａｎｏｌｕｃ阻害剤 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10815247B2 (enExample) |
| EP (1) | EP3562823B1 (enExample) |
| JP (1) | JP7161475B2 (enExample) |
| WO (1) | WO2018125992A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10513694B2 (en) | 2015-06-25 | 2019-12-24 | Promega Corporation | Thienopyrrole compounds and uses thereof |
| WO2018125992A1 (en) | 2016-12-28 | 2018-07-05 | Promega Corporation | Functionalized nanoluc inhibitors |
| US12181452B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
| US11709155B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US12180581B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| WO2019232384A1 (en) * | 2018-06-01 | 2019-12-05 | Promega Corporation | Inhibitors of oplophorus luciferase-derived bioluminescent complexes |
| US11691976B2 (en) | 2018-08-23 | 2023-07-04 | Promega Corporation | Coelenterazine analogues |
| JP6671574B1 (ja) | 2018-08-27 | 2020-03-25 | 大日本住友製薬株式会社 | 光学活性なアザビシクロ環誘導体 |
| CN111848657B (zh) * | 2019-04-24 | 2021-12-31 | 中国科学院上海药物研究所 | 靶向酪氨酸激酶识别的可逆性荧光化合物及其制备方法和应用 |
| US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
| EP4628889A3 (en) | 2020-09-24 | 2025-12-10 | Waters Technologies Corporation | Chromatographic hardware improvements for the separation of reactive molecules |
| EP4602045A1 (en) | 2022-10-14 | 2025-08-20 | Promega Corporation | Coelenterazine analogues |
| US20250206747A1 (en) | 2023-12-20 | 2025-06-26 | Promega Corporation | Coelenterazine analogues |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3828535A1 (de) | 1988-08-23 | 1990-03-08 | Basf Ag | Benzimidazol-2-carbonsaeureanilide, ihre verwendung als lichtschutzmittel fuer organisches material und mit diesen aniliden stabilisiertes organisches material |
| US5283179A (en) | 1990-09-10 | 1994-02-01 | Promega Corporation | Luciferase assay method |
| EP0746544B1 (en) * | 1994-02-22 | 1998-09-09 | Merrell Pharmaceuticals Inc. | Novel indole derivatives useful to treat estrogen-related neoplasms and disorders |
| US7268229B2 (en) | 2001-11-02 | 2007-09-11 | Promega Corporation | Compounds to co-localize luminophores with luminescent proteins |
| EP1314733A1 (en) | 2001-11-22 | 2003-05-28 | Aventis Pharma Deutschland GmbH | Indole-2-carboxamides as factor Xa inhibitors |
| JP2007537296A (ja) | 2004-05-14 | 2007-12-20 | アボット・ラボラトリーズ | 治療薬としてのキナーゼ阻害薬 |
| FR2897061B1 (fr) | 2006-02-03 | 2010-09-03 | Sanofi Aventis | Derives de n-heteroaryl-carboxamides tricycliques contenant un motif benzimidazole, leur preparation et leur application en therapeutique. |
| US20080248511A1 (en) | 2007-03-26 | 2008-10-09 | Promega Corporation | Methods to quench light from optical reactions |
| US8163910B2 (en) | 2007-10-03 | 2012-04-24 | Elitech Holding B.V. | Amide-substituted xanthene dyes |
| US8338392B2 (en) | 2008-02-20 | 2012-12-25 | The Wistar Institute | MicroRNA modulators and method for identifying and using the same |
| US20100305093A1 (en) | 2009-04-09 | 2010-12-02 | Exelixis, Inc. | Inhibitors of mTOR and Methods of Making and Using |
| DK2456864T3 (en) | 2009-05-01 | 2015-12-21 | Promega Corp | SYNTHETIC OPLOPHORUS luciferases WITH IMPROVED LIGHT MISSION |
| US20130178453A1 (en) | 2010-02-09 | 2013-07-11 | Ironwood Pharmaceuticals, Inc. | Cannabinoid Agonists |
| PT2635583E (pt) | 2010-11-02 | 2015-09-11 | Promega Corp | Derivados da coelenterazina e métodos de utilização da mesma |
| US8669103B2 (en) | 2010-11-02 | 2014-03-11 | Promega Corporation | Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use |
| EP2751089B1 (en) | 2011-09-02 | 2018-11-14 | Promega Corporation | Compounds and methods for assaying redox state of metabolically active cells and methods for measuring nad(p)/nad(p)h |
| EP2900833B1 (en) | 2012-09-26 | 2018-05-30 | Promega Corporation | Real-time monitoring |
| WO2015067302A1 (en) | 2013-11-05 | 2015-05-14 | Ecole Polytechnique Federale De Lausanne (Epfl) | Sensor molecules and uses thereof |
| WO2015116867A1 (en) | 2014-01-29 | 2015-08-06 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| US9927430B2 (en) | 2014-01-29 | 2018-03-27 | Promega Corporation | Pro-substrates for live cell applications |
| EP3304078B1 (en) | 2015-06-05 | 2022-08-31 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
| US10513694B2 (en) | 2015-06-25 | 2019-12-24 | Promega Corporation | Thienopyrrole compounds and uses thereof |
| WO2018125992A1 (en) | 2016-12-28 | 2018-07-05 | Promega Corporation | Functionalized nanoluc inhibitors |
-
2017
- 2017-12-28 WO PCT/US2017/068686 patent/WO2018125992A1/en not_active Ceased
- 2017-12-28 EP EP17832700.3A patent/EP3562823B1/en active Active
- 2017-12-28 JP JP2019535843A patent/JP7161475B2/ja active Active
- 2017-12-28 US US15/856,302 patent/US10815247B2/en active Active
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