|
GB8808015D0
(en)
|
1988-04-06 |
1988-05-05 |
Ritter M A |
Chemical compounds
|
|
WO1990005183A1
(en)
|
1988-10-31 |
1990-05-17 |
Immunex Corporation |
Interleukin-4 receptors
|
|
AU665763B2
(en)
|
1991-05-03 |
1996-01-18 |
Seragen, Inc. |
Interleukin receptor targeted molecules for treatment of inflammatory arthritis
|
|
JP3315427B2
(ja)
|
1992-03-05 |
2002-08-19 |
大日本除蟲菊株式会社 |
皮膚炎治療剤
|
|
US5714146A
(en)
|
1992-08-26 |
1998-02-03 |
Board Of Regents Of The University Of Washington |
IL-4 bone therapy
|
|
EP0604693A1
(en)
|
1992-12-29 |
1994-07-06 |
Schering-Plough |
Monoclonal antibodies against the human interleukin-4 receptor and hybridomas producing the same
|
|
RU2162711C2
(ru)
|
1993-09-07 |
2001-02-10 |
Смитклайн Бичам Корпорейшн |
Рекомбинантные il4-антитела, используемые для лечения нарушений, связанных с действием il4
|
|
EP1113818B1
(en)
|
1998-09-18 |
2006-05-17 |
Dynavax Technologies Corporation |
METHODS OF TREATING IgE-ASSOCIATED DISORDERS AND COMPOSITIONS FOR USE THEREIN
|
|
US6927044B2
(en)
|
1998-09-25 |
2005-08-09 |
Regeneron Pharmaceuticals, Inc. |
IL-1 receptor based cytokine traps
|
|
EP1283851B1
(en)
|
2000-05-26 |
2012-03-28 |
Immunex Corporation |
Use of il-4r antibodies and compositions thereof
|
|
US7879328B2
(en)
|
2000-06-16 |
2011-02-01 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator
|
|
KR100572408B1
(ko)
|
2000-07-26 |
2006-04-19 |
가부시키가이샤 호오도 |
진양성 조성물 및 창상치유촉진 조성물
|
|
CN1529618A
(zh)
|
2000-12-22 |
2004-09-15 |
�Ʒ� |
耐受性诱导
|
|
US20030103938A1
(en)
|
2001-05-09 |
2003-06-05 |
Alk-Abello A/S |
Pharmaceutical compositions for preventing or treating Th1 and Th2 cell related diseases by modulating the Th1/Th2 ratio
|
|
BR0117009A
(pt)
|
2001-05-11 |
2004-04-20 |
Novartis Ag |
Composiçoes para utilização no tratamento de distúrbios associados a ige
|
|
JP4339598B2
(ja)
|
2001-05-23 |
2009-10-07 |
デュオトール アーベー |
毒素サブユニットまたはそのフラグメントと共に、又はこれとコンジュゲートされたアレルゲンの経皮投与によるアレルギー反応の抑制
|
|
WO2003048083A2
(en)
|
2001-11-30 |
2003-06-12 |
Biogen Idec Ma Inc. |
Antibodies against monocyte chemotactic proteins
|
|
CN1326879C
(zh)
|
2002-03-29 |
2007-07-18 |
先灵公司 |
人源抗白细胞介素5单克隆抗体及其制备方法和包含这些抗体的组合物
|
|
WO2004047793A1
(en)
|
2002-11-26 |
2004-06-10 |
Alk-Abelló A/S |
Pharmaceutical allergen product
|
|
CA2514839A1
(en)
|
2003-02-01 |
2004-08-19 |
Tanox, Inc. |
A method for generating high affinity antibodies
|
|
US7923209B2
(en)
|
2003-03-14 |
2011-04-12 |
Anergis, S.A. |
Allergen peptide fragments and use thereof
|
|
UA93653C2
(ru)
|
2003-11-07 |
2011-03-10 |
Иммунекс Корпорейшн |
Выделенное антитело, kotopoe специфически связывается c человеческим рецептором il-4 (il-4r)
|
|
AU2004309373A1
(en)
|
2003-12-22 |
2005-07-14 |
Amgen Inc. |
Methods for identifying functional antibodies
|
|
WO2005085284A1
(en)
|
2004-02-27 |
2005-09-15 |
Regeneron Pharmaceuticals, Inc. |
Il-4/il-13 sepecific polypetides and therapeutic uses thereof
|
|
US20090098142A1
(en)
|
2004-06-09 |
2009-04-16 |
Kasaian Marion T |
Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
|
|
AR049390A1
(es)
*
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
|
JP5234445B2
(ja)
|
2004-10-05 |
2013-07-10 |
源一郎 杣 |
薬剤
|
|
US8030003B2
(en)
|
2004-12-07 |
2011-10-04 |
Children's Hospital Medical Center |
Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3
|
|
TWI306862B
(en)
|
2005-01-03 |
2009-03-01 |
Hoffmann La Roche |
Antibodies against il-13 receptor alpha 1 and uses thereof
|
|
JP5065253B2
(ja)
|
2005-05-06 |
2012-10-31 |
ザイモジェネティクス, インコーポレイテッド |
Il−31モノクローナル抗体とその使用法
|
|
US8679545B2
(en)
|
2005-11-12 |
2014-03-25 |
The Regents Of The University Of California |
Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
|
|
US8324192B2
(en)
|
2005-11-12 |
2012-12-04 |
The Regents Of The University Of California |
Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
|
|
MY159787A
(en)
|
2006-06-02 |
2017-01-31 |
Regeneron Pharma |
High affinity antibodies to human il-6 receptor
|
|
JP4221018B2
(ja)
|
2006-08-31 |
2009-02-12 |
トヨタ自動車株式会社 |
頭部保護エアバッグ装置
|
|
MX2009003393A
(es)
|
2006-10-02 |
2009-05-11 |
Regeneron Pharma |
Anticuerpos humanos de alta afinidad para el receptor de il-4 humano.
|
|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
KR101555068B1
(ko)
|
2007-03-22 |
2015-10-06 |
제넨테크, 인크. |
막 결합형 ige에 결합하는 세포자멸성 항-ige 항체
|
|
EP2022507A1
(en)
|
2007-08-07 |
2009-02-11 |
Universität Hamburg |
Antibody compositions specific for lgE, lgG4 and lgA epitopes as tools for the design of hypoallergenic molecules for specific immunotherapy
|
|
US8637239B2
(en)
|
2007-11-05 |
2014-01-28 |
The Board Of Trustees Of The University Of Illinois |
Minimally-invasive measurement of esophageal inflammation
|
|
US8092804B2
(en)
|
2007-12-21 |
2012-01-10 |
Medimmune Limited |
Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
|
|
DE202008006598U1
(de)
|
2008-04-11 |
2008-10-02 |
Alk-Abelló A/S |
Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung
|
|
US20090264392A1
(en)
|
2008-04-21 |
2009-10-22 |
Meritage Pharma, Inc. |
Treating eosinophilic esophagitis
|
|
CA2748712A1
(en)
|
2008-12-01 |
2010-06-10 |
Children's Hospital Medical Center |
Methods of determining efficacy of glucocorticoid treatment of eosinophilic esophagitis
|
|
US20120088814A1
(en)
|
2009-03-31 |
2012-04-12 |
Isis Pharmaceuticals, Inc. |
Methods of modulating an immune response to a viral infection
|
|
US8497528B2
(en)
|
2010-05-06 |
2013-07-30 |
Taiwan Semiconductor Manufacturing Company, Ltd. |
Method for fabricating a strained structure
|
|
CN102596237A
(zh)
|
2009-09-07 |
2012-07-18 |
Dbv技术公司 |
治疗嗜酸细胞性食管炎的方法
|
|
US8993347B2
(en)
*
|
2009-12-17 |
2015-03-31 |
Cornell University |
Methods for detecting antibodies in mucosal samples and device for sampling mucosal material
|
|
EP2585075B8
(en)
|
2010-06-24 |
2021-09-22 |
ViroPharma Biologics LLC |
Methods of treatment for esophageal inflammation
|
|
PH12013500672A1
(en)
|
2010-10-06 |
2013-06-03 |
Regeneron Pharma |
Stabilized formulations containing anti-interleukin-4-receptor (il-4r) antibodies
|
|
CN103298937B
(zh)
|
2010-11-17 |
2016-05-25 |
中外制药株式会社 |
具有代替凝血因子viii的功能的功能的多特异性抗原结合分子
|
|
RU2453303C1
(ru)
|
2010-12-23 |
2012-06-20 |
Общество с ограниченной ответственностью "ЦитоНИР" (ООО "ЦитоНИР") |
Фармацевтическая композиция для лечения атопического дерматита
|
|
WO2012094643A2
(en)
|
2011-01-06 |
2012-07-12 |
Children's Hospital Medical Center |
Esophageal cytokine expression profiles in eosinophilic esophagitis
|
|
US20130052190A1
(en)
|
2011-02-22 |
2013-02-28 |
Oxagen Limited |
CRTH2 Antagonists for Treatment of Eosinophilic Diseases and Conditions
|
|
EP2723899B1
(en)
|
2011-06-21 |
2020-11-18 |
Children's Hospital Medical Center |
Diagnostic methods for eosinophilic esophagitis
|
|
US8790651B2
(en)
|
2011-07-21 |
2014-07-29 |
Zoetis Llc |
Interleukin-31 monoclonal antibody
|
|
EP2763683A1
(en)
|
2011-10-06 |
2014-08-13 |
N.V. Nutricia |
Treatment of eosinophilic esophagitis
|
|
MX2014007239A
(es)
|
2011-12-16 |
2014-08-08 |
Atopix Therapeutics Ltd |
Combinacion de un antagonista crth2 y un inhibidor de bomba de proton para el tratamiento de esofagitis eosinofilica.
|
|
EP2809684A1
(en)
|
2012-01-31 |
2014-12-10 |
Genentech, Inc. |
Anti-ig-e m1' antibodies and methods using same
|
|
WO2013155010A1
(en)
|
2012-04-09 |
2013-10-17 |
Children's Hospital Medical Center |
Non-invasive biomarkers for eosinophilic esophagitis
|
|
PT3470432T
(pt)
|
2012-08-21 |
2021-12-14 |
Regeneron Pharma |
Métodos para tratamento ou prevenção da asma por meio de administração de um antagonista de il-4r
|
|
BR112015005048A8
(pt)
*
|
2012-09-07 |
2018-01-30 |
Regeneron Pharma |
métodos para tratar dermatite atópica por administração de antagonista il-4r
|
|
WO2014059178A1
(en)
|
2012-10-10 |
2014-04-17 |
Rhode Island Hospital |
Differential expression of novel protein markers for the diagnosis and treatment of eosinophilic esophagitis
|
|
PL2953972T3
(pl)
|
2013-02-05 |
2021-03-08 |
Engmab Sàrl |
Metoda wyboru przeciwciał przeciwko bcma
|
|
TWI697334B
(zh)
|
2013-06-04 |
2020-07-01 |
美商再生元醫藥公司 |
藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
|
|
KR20210132232A
(ko)
*
|
2013-06-21 |
2021-11-03 |
사노피 바이오테크놀로지 |
Il-4r 길항제를 투여함에 의한 비용종증의 치료 방법
|
|
TWI682781B
(zh)
|
2013-07-11 |
2020-01-21 |
美商再生元醫藥公司 |
藉由投與il-4r抑制劑治療嗜酸性食道炎的方法
|
|
RU2552929C1
(ru)
|
2013-11-14 |
2015-06-10 |
Общество С Ограниченной Ответственностью "Фарминтерпрайсез" |
Фармацевтическая композиция, содержащая производные глутаримидов, и их применение для лечения эозинофильных заболеваний
|
|
IL315136A
(en)
|
2014-02-21 |
2024-10-01 |
Sanofi Biotechnology |
Methods for treating or preventing asthma by administering an il-4rantagonist
|
|
JP6526037B2
(ja)
|
2014-02-28 |
2019-06-05 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
Il−4rアンタゴニストを投与することによる皮膚感染を処置するための方法
|
|
EP3218412A1
(en)
|
2014-11-14 |
2017-09-20 |
Sanofi Biotechnology |
Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist
|
|
AU2017220184B2
(en)
*
|
2016-02-19 |
2024-04-18 |
Regeneron Pharmaceuticals, Inc. |
Methods for enhancing efficacy of a vaccine by administering an IL-4R antagonist
|
|
TWI728172B
(zh)
|
2016-08-18 |
2021-05-21 |
美商愛戴爾製藥股份有限公司 |
治療嗜伊紅性食道炎之方法
|
|
CA3035202A1
(en)
|
2016-09-01 |
2018-03-08 |
Regeneron Pharmaceuticals, Inc. |
Methods for preventing or treating allergy by administering an il-4r antagonist
|
|
CA3037499A1
(en)
|
2016-09-22 |
2018-03-29 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating severe atopic dermatitis by administering an il-4r inhibitor
|
|
IL268349B2
(en)
|
2017-02-17 |
2024-08-01 |
Hutchinson Fred Cancer Res |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
US20200179511A1
(en)
|
2017-04-28 |
2020-06-11 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
US11053309B2
(en)
|
2017-08-04 |
2021-07-06 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating active eosinophilic esophagitis
|
|
PT3515465T
(pt)
|
2017-08-18 |
2024-03-04 |
Regeneron Pharma |
Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r
|
|
CA3079946A1
(en)
|
2017-10-30 |
2019-05-09 |
Sanofi Biotechnology |
Methods for treating or preventing asthma by administering an il-4r antagonist
|
|
JP2021523188A
(ja)
|
2018-05-13 |
2021-09-02 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
Il−4r阻害剤を投与することによって重度のアトピー性皮膚炎を処置するための方法
|
|
KR20250158077A
(ko)
|
2018-06-14 |
2025-11-05 |
아지노모토 가부시키가이샤 |
항체에 대한 친화성 물질 및 생체 직교성 관능기를 갖는 화합물 또는 이의 염
|
|
CN121102493A
(zh)
|
2019-03-21 |
2025-12-12 |
瑞泽恩制药公司 |
用于治疗过敏症的il-4/il-13途径抑制剂和浆细胞消融的组合
|
|
WO2020223541A1
(en)
|
2019-05-01 |
2020-11-05 |
Sanofi Biotechnology |
Methods for treating or preventing asthma by administering an il-33 antagonist
|
|
WO2021026203A1
(en)
|
2019-08-05 |
2021-02-11 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an il-4r antagonist
|
|
MX2022001247A
(es)
|
2019-08-05 |
2022-04-25 |
Regeneron Pharma |
Metodos para tratar dermatitis atopica mediante la administracion de un antagonista il-4r.
|
|
CA3161037A1
(en)
|
2019-12-09 |
2021-06-17 |
Sanofi Biotechnology |
Methods for treating digitally-identified il-4/il-13 related disorders
|
|
EP4126951A1
(en)
|
2020-03-27 |
2023-02-08 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating atopic dermatitis by administering an il-4r antagonist
|
|
BR112022022235A2
(pt)
|
2020-05-22 |
2023-03-28 |
Regeneron Pharma |
Métodos para tratamento de esofagite eosinofílica através da administração de inibidor de il-4r
|
|
JP2023544406A
(ja)
|
2020-10-05 |
2023-10-23 |
サノフィ・バイオテクノロジー |
Il-4rアンタゴニストを投与することによって小児対象における喘息を治療するための方法
|
|
KR20230130681A
(ko)
|
2021-01-08 |
2023-09-12 |
리제너론 파아마슈티컬스, 인크. |
Il-4r 길항제 투여에 의한 땅콩 알레르기를 치료하는방법 및 땅콩 알레르기원 특이적 면역치료를 강화하는 방법
|