MX2020012064A - Metodos para tratar la dermatitis atopica administrando un inhibidor de il-4r. - Google Patents

Metodos para tratar la dermatitis atopica administrando un inhibidor de il-4r.

Info

Publication number
MX2020012064A
MX2020012064A MX2020012064A MX2020012064A MX2020012064A MX 2020012064 A MX2020012064 A MX 2020012064A MX 2020012064 A MX2020012064 A MX 2020012064A MX 2020012064 A MX2020012064 A MX 2020012064A MX 2020012064 A MX2020012064 A MX 2020012064A
Authority
MX
Mexico
Prior art keywords
methods
inhibitor
atopic dermatitis
administering
treating atopic
Prior art date
Application number
MX2020012064A
Other languages
English (en)
Inventor
Ashish Bansal
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of MX2020012064A publication Critical patent/MX2020012064A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención proporciona métodos para tratar la dermatitis atópica (DA) de moderada a grave o grave. Los métodos de la presente invención comprenden administrar a un sujeto que lo necesite una o más dosis de un inhibidor del receptor de interleucina-4 (IL-4R) tal como un anticuerpo anti-IL-4R.
MX2020012064A 2018-05-13 2019-05-10 Metodos para tratar la dermatitis atopica administrando un inhibidor de il-4r. MX2020012064A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862670824P 2018-05-13 2018-05-13
US201962840493P 2019-04-30 2019-04-30
PCT/US2019/031801 WO2019222055A1 (en) 2018-05-13 2019-05-10 Methods for treating atopic dermatitis by administering an il-4r inhibitor

Publications (1)

Publication Number Publication Date
MX2020012064A true MX2020012064A (es) 2021-04-13

Family

ID=66641513

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020012064A MX2020012064A (es) 2018-05-13 2019-05-10 Metodos para tratar la dermatitis atopica administrando un inhibidor de il-4r.

Country Status (12)

Country Link
US (2) US11292847B2 (es)
EP (1) EP3793597A1 (es)
JP (2) JP2021523188A (es)
KR (1) KR20210010518A (es)
CN (1) CN112153982A (es)
AU (1) AU2019270940A1 (es)
BR (1) BR112020020387A2 (es)
CA (1) CA3099066A1 (es)
MA (1) MA52624A (es)
MX (1) MX2020012064A (es)
SG (1) SG11202009371WA (es)
WO (1) WO2019222055A1 (es)

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WO2019028367A1 (en) 2017-08-04 2019-02-07 Regeneron Pharmaceuticals, Inc. METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES
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Also Published As

Publication number Publication date
CA3099066A1 (en) 2019-11-21
EP3793597A1 (en) 2021-03-24
NZ769607A (en) 2023-11-24
MA52624A (fr) 2021-03-24
AU2019270940A1 (en) 2020-11-26
JP2021523188A (ja) 2021-09-02
US11292847B2 (en) 2022-04-05
CN112153982A (zh) 2020-12-29
KR20210010518A (ko) 2021-01-27
BR112020020387A2 (pt) 2021-01-19
US20220298250A1 (en) 2022-09-22
US20190345253A1 (en) 2019-11-14
SG11202009371WA (en) 2020-10-29
WO2019222055A1 (en) 2019-11-21
JP2024038234A (ja) 2024-03-19

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