KR102872485B1 - Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법 - Google Patents

Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법

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KR102872485B1
KR102872485B1 KR1020227037662A KR20227037662A KR102872485B1 KR 102872485 B1 KR102872485 B1 KR 102872485B1 KR 1020227037662 A KR1020227037662 A KR 1020227037662A KR 20227037662 A KR20227037662 A KR 20227037662A KR 102872485 B1 KR102872485 B1 KR 102872485B1
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antagonist
pharmaceutical composition
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KR20220151021A (ko
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쥬니퍼 디. 해밀턴
브라이언 엔. 스완손
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리제너론 파아마슈티컬스, 인크.
사노피 바이오테크놀로지
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Application filed by 리제너론 파아마슈티컬스, 인크., 사노피 바이오테크놀로지 filed Critical 리제너론 파아마슈티컬스, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
KR1020227037662A 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법 Active KR102872485B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247014525A KR20240065318A (ko) 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662382501P 2016-09-01 2016-09-01
US62/382,501 2016-09-01
US201662425726P 2016-11-23 2016-11-23
US62/425,726 2016-11-23
PCT/US2017/049538 WO2018045130A1 (en) 2016-09-01 2017-08-31 Methods for preventing or treating allergy by administering an il-4r antagonist
KR1020197009282A KR102462039B1 (ko) 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법

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KR1020197009282A Division KR102462039B1 (ko) 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법

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KR1020247014525A Division KR20240065318A (ko) 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법

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KR20220151021A KR20220151021A (ko) 2022-11-11
KR102872485B1 true KR102872485B1 (ko) 2025-10-20

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KR1020227037662A Active KR102872485B1 (ko) 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법
KR1020247014525A Pending KR20240065318A (ko) 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법
KR1020197009282A Active KR102462039B1 (ko) 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법

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KR1020197009282A Active KR102462039B1 (ko) 2016-09-01 2017-08-31 Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법

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US (2) US11771743B2 (cg-RX-API-DMAC7.html)
EP (2) EP3506931B1 (cg-RX-API-DMAC7.html)
JP (3) JP7584218B2 (cg-RX-API-DMAC7.html)
KR (3) KR102872485B1 (cg-RX-API-DMAC7.html)
CN (2) CN109789196B (cg-RX-API-DMAC7.html)
CA (1) CA3035202A1 (cg-RX-API-DMAC7.html)
ES (1) ES2994774T3 (cg-RX-API-DMAC7.html)
HU (1) HUE067888T2 (cg-RX-API-DMAC7.html)
IL (2) IL320424A (cg-RX-API-DMAC7.html)
MA (1) MA46098B1 (cg-RX-API-DMAC7.html)
MX (2) MX2019002344A (cg-RX-API-DMAC7.html)
PL (1) PL3506931T3 (cg-RX-API-DMAC7.html)
PT (1) PT3506931T (cg-RX-API-DMAC7.html)
WO (1) WO2018045130A1 (cg-RX-API-DMAC7.html)

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