JP2019505597A5 - - Google Patents
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- JP2019505597A5 JP2019505597A5 JP2018563393A JP2018563393A JP2019505597A5 JP 2019505597 A5 JP2019505597 A5 JP 2019505597A5 JP 2018563393 A JP2018563393 A JP 2018563393A JP 2018563393 A JP2018563393 A JP 2018563393A JP 2019505597 A5 JP2019505597 A5 JP 2019505597A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662298726P | 2016-02-23 | 2016-02-23 | |
| US62/298,726 | 2016-02-23 | ||
| PCT/US2017/018790 WO2017147102A1 (en) | 2016-02-23 | 2017-02-22 | Heteroaryl inhibitors of pad4 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019505597A JP2019505597A (ja) | 2019-02-28 |
| JP2019505597A5 true JP2019505597A5 (https=) | 2020-04-02 |
| JP6926126B2 JP6926126B2 (ja) | 2021-08-25 |
Family
ID=58191708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018563393A Active JP6926126B2 (ja) | 2016-02-23 | 2017-02-22 | Ｐａｄ４のヘテロアリール阻害剤 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11198681B2 (https=) |
| EP (1) | EP3419969B1 (https=) |
| JP (1) | JP6926126B2 (https=) |
| KR (1) | KR102759005B1 (https=) |
| CN (1) | CN109071497B (https=) |
| AR (1) | AR107694A1 (https=) |
| AU (1) | AU2017223416A1 (https=) |
| BR (1) | BR112018016433A2 (https=) |
| CA (1) | CA3015482A1 (https=) |
| EA (1) | EA201891910A1 (https=) |
| ES (1) | ES2770102T3 (https=) |
| IL (1) | IL261167A (https=) |
| MX (1) | MX2018009773A (https=) |
| SG (1) | SG11201807021UA (https=) |
| TW (1) | TW201825476A (https=) |
| UY (1) | UY37134A (https=) |
| WO (1) | WO2017147102A1 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3015482A1 (en) | 2016-02-23 | 2017-08-31 | Padlock Therapeutics, Inc. | Heteroaryl inhibitors of pad4 |
| WO2018022897A1 (en) | 2016-07-27 | 2018-02-01 | Padlock Therapeutics, Inc. | Covalent inhibitors of pad4 |
| US11026937B2 (en) | 2016-09-12 | 2021-06-08 | Padlock Therapeutics, Inc. | Heteroaryl inhibitors of PAD4 |
| JP7504349B2 (ja) * | 2017-09-19 | 2024-06-24 | 三菱瓦斯化学株式会社 | 半導体リソグラフィー膜形成組成物、並びにレジストパターン形成方法及びデバイス |
| RU2764243C2 (ru) * | 2017-09-22 | 2022-01-14 | ДЖУБИЛАНТ ЭПИПЭД ЭлЭлСи | Гетероциклические соединения в качестве ингибиторов PAD |
| AU2018352142B2 (en) | 2017-10-18 | 2022-08-25 | Jubilant Epipad LLC | Imidazo-pyridine compounds as PAD inhibitors |
| US11629135B2 (en) | 2017-11-06 | 2023-04-18 | Jubilant Prodell Llc | Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation |
| PT3704120T (pt) | 2017-11-24 | 2024-07-03 | Jubilant Episcribe Llc | Compostos heterocíclicos como inibidores de prmt5 |
| WO2019122202A1 (en) * | 2017-12-20 | 2019-06-27 | Ecole Polytechnique Federale De Lausanne (Epfl) | Sting inhibitors |
| MX2020009517A (es) | 2018-03-13 | 2021-01-20 | Jubilant Prodel LLC | Compuestos biciclicos como inhibidores de la interaccion/activacio n de pdl/pd-l1. |
| JP7447080B2 (ja) * | 2018-08-08 | 2024-03-11 | ブリストル－マイヤーズ スクイブ カンパニー | Ｐａｄ４阻害剤としての置換チエノピロール |
| MX2021001565A (es) | 2018-08-08 | 2021-04-19 | Bristol Myers Squibb Co | Inhibidores tipo indol y azaindol de enzimas peptidil arginina deiminasas (pad). |
| US20220348562A1 (en) * | 2018-08-08 | 2022-11-03 | Bristol-Myers Squibb Company | Benzimidazole inhibitors of pad enzymes |
| KR102459614B1 (ko) * | 2019-08-30 | 2022-10-31 | 주식회사 티에스디라이프사이언스 | 이미다조피리딘 유도체 및 이를 유효성분으로 함유하는 약학적 조성물 |
| TW202115083A (zh) * | 2019-09-27 | 2021-04-16 | 大陸商南京藥捷安康生物科技有限公司 | 肽醯精胺酸脫亞胺酶抑制劑及其用途 |
| CN115210229A (zh) | 2020-01-03 | 2022-10-18 | 博格有限责任公司 | 多环酰胺作为治疗癌症的ube2k调节剂 |
| WO2021158840A1 (en) | 2020-02-06 | 2021-08-12 | Bristol-Myers Squibb Company | Macrocyclic pad4 inhibitors useful as immunosuppressant |
| CN113248507A (zh) * | 2020-02-09 | 2021-08-13 | 上海茂晟康慧科技有限公司 | 瑞德西韦关键中间体7-卤代吡咯并[1,2-f][1,2,4]三嗪-4-胺的合成方法 |
| TW202140477A (zh) | 2020-02-12 | 2021-11-01 | 美商必治妥美雅史谷比公司 | 雜環ｐａｄ４抑制劑 |
| WO2021222353A1 (en) | 2020-04-30 | 2021-11-04 | Gilead Sciences, Inc. | Macrocyclic inhibitors of peptidylarginine deiminases |
| CN112618546B (zh) * | 2020-12-22 | 2022-03-01 | 陈昊 | Pad4抑制剂在制备放射治疗增敏药物方面的应用 |
| TW202233174A (zh) | 2020-12-22 | 2022-09-01 | 美商基利科學股份有限公司 | 肽基精胺酸去亞胺酶之抑制劑 |
| WO2022140390A1 (en) | 2020-12-22 | 2022-06-30 | Gilead Sciences, Inc. | Inhibitors of peptidylarginine deiminases |
| KR20220122879A (ko) * | 2021-02-26 | 2022-09-05 | 주식회사 티에스디라이프사이언스 | 이미다조피리딘 유도체 및 이를 유효성분으로 함유하는 약학적 조성물 |
| EP4698530A1 (en) | 2023-04-18 | 2026-02-25 | Kallyope, Inc. | Nk3 modulators and uses thereof |
| IL324670A (en) | 2023-06-30 | 2026-01-01 | Bristol Myers Squibb Co | KRAS inhibitors |
| KR20260041867A (ko) | 2023-07-21 | 2026-03-27 | 브리스톨-마이어스 스큅 컴퍼니 | Pad4 조정제의 시트룰린화 및 활성을 평가하는 방법 |
| WO2025080781A1 (en) * | 2023-10-12 | 2025-04-17 | Kallyope, Inc. | Nk3 modulators and uses thereof |
| WO2026020127A2 (en) | 2024-07-19 | 2026-01-22 | Bristol-Myers Squibb Company | Methods of assessing citrullination and activity of pad2 modulators |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101916443B1 (ko) | 2012-07-26 | 2018-11-08 | 글락소 그룹 리미티드 | Pad4 억제제로서의 2-(아자인돌-2-일) 벤즈이미다졸 |
| KR20180005250A (ko) | 2015-05-21 | 2018-01-15 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | Pad4 억제제로서의 벤조이미다졸 유도체 |
| AR107032A1 (es) * | 2015-12-09 | 2018-03-14 | Padlock Therapeutics Inc | Inhibidores bicíclicos de pad4 |
| AR107030A1 (es) * | 2015-12-09 | 2018-03-14 | Padlock Therapeutics Inc | Inhibidores aza-bencimidazol de pad4 |
| CA3015482A1 (en) | 2016-02-23 | 2017-08-31 | Padlock Therapeutics, Inc. | Heteroaryl inhibitors of pad4 |
| WO2018022897A1 (en) | 2016-07-27 | 2018-02-01 | Padlock Therapeutics, Inc. | Covalent inhibitors of pad4 |
| US11026937B2 (en) | 2016-09-12 | 2021-06-08 | Padlock Therapeutics, Inc. | Heteroaryl inhibitors of PAD4 |
-
2017
- 2017-02-22 CA CA3015482A patent/CA3015482A1/en not_active Abandoned
- 2017-02-22 TW TW106105844A patent/TW201825476A/zh unknown
- 2017-02-22 AR ARP170100442A patent/AR107694A1/es unknown
- 2017-02-22 CN CN201780025089.9A patent/CN109071497B/zh active Active
- 2017-02-22 BR BR112018016433-0A patent/BR112018016433A2/pt not_active IP Right Cessation
- 2017-02-22 AU AU2017223416A patent/AU2017223416A1/en not_active Abandoned
- 2017-02-22 US US16/078,376 patent/US11198681B2/en active Active
- 2017-02-22 EA EA201891910A patent/EA201891910A1/ru unknown
- 2017-02-22 EP EP17708142.9A patent/EP3419969B1/en active Active
- 2017-02-22 ES ES17708142T patent/ES2770102T3/es active Active
- 2017-02-22 SG SG11201807021UA patent/SG11201807021UA/en unknown
- 2017-02-22 WO PCT/US2017/018790 patent/WO2017147102A1/en not_active Ceased
- 2017-02-22 KR KR1020187027136A patent/KR102759005B1/ko active Active
- 2017-02-22 MX MX2018009773A patent/MX2018009773A/es unknown
- 2017-02-22 UY UY0001037134A patent/UY37134A/es unknown
- 2017-02-22 JP JP2018563393A patent/JP6926126B2/ja active Active
-
2018
- 2018-08-15 IL IL261167A patent/IL261167A/en unknown
-
2021
- 2021-11-09 US US17/522,348 patent/US11897866B2/en active Active
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