JP6926126B2 - Ｐａｄ４のヘテロアリール阻害剤 - Google Patents

Ｐａｄ４のヘテロアリール阻害剤 Download PDF

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JP6926126B2
JP6926126B2 JP2018563393A JP2018563393A JP6926126B2 JP 6926126 B2 JP6926126 B2 JP 6926126B2 JP 2018563393 A JP2018563393 A JP 2018563393A JP 2018563393 A JP2018563393 A JP 2018563393A JP 6926126 B2 JP6926126 B2 JP 6926126B2
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methyl
disease
mmol
ring
pharmaceutically acceptable
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JP2019505597A5 (https=
JP2019505597A (ja
Inventor
ラジェシュ・デブラジ
グナナサンバンダム・クマラベル
ホリー・アットン
エドワード・ボーモント
エリーズ・ガドゥロー
ローラ・グリーブ
フィリップ・スティーブン・ケリー
クリスティーナ・レッチ
ミルコ・メニコーニ
ナット・モンク
ジョーダン・パルフリー
コスタス・パパドポウロス
ヘザー・タイ
フィリップ・エイ・ウッズ
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Padlock Therapeutics Inc
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Padlock Therapeutics Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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