|
ES324609A1
(es)
|
1966-03-24 |
1966-12-16 |
Patronato De Investigacien Cie |
Procedimiento para la preparaciën de indolil-alquil hidrazinas
|
|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
JPS5666928A
(en)
|
1979-11-05 |
1981-06-05 |
Hitachi Ltd |
Pulse generating circuit
|
|
US4352795A
(en)
|
1981-01-29 |
1982-10-05 |
Warner-Lambert Company |
7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
JPS61134325A
(ja)
|
1984-12-04 |
1986-06-21 |
Teijin Ltd |
ハイブリツド抗体遺伝子の発現方法
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
ZW10887A1
(en)
|
1986-06-25 |
1987-10-28 |
Injectall Ltd |
Improvements in apparatus for injecting substances into liquids
|
|
DK8189A
(da)
|
1988-01-12 |
1989-07-13 |
Bunge Australia |
Antigen-antistof-konjugater, deres fremstilling og anvendelse
|
|
DE3815826A1
(de)
|
1988-05-09 |
1989-11-23 |
Henkel Kgaa |
Verfahren zur herstellung von vicinal diacyloxysubstituierten verbindungen
|
|
US5470829A
(en)
|
1988-11-17 |
1995-11-28 |
Prisell; Per |
Pharmaceutical preparation
|
|
EP0401384B1
(en)
|
1988-12-22 |
1996-03-13 |
Kirin-Amgen, Inc. |
Chemically modified granulocyte colony stimulating factor
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5089261A
(en)
|
1989-01-23 |
1992-02-18 |
Cetus Corporation |
Preparation of a polymer/interleukin-2 conjugate
|
|
US5122614A
(en)
|
1989-04-19 |
1992-06-16 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
US5324844A
(en)
|
1989-04-19 |
1994-06-28 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
EP0470128B2
(en)
|
1989-04-19 |
2003-08-13 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
IL90193A
(en)
|
1989-05-04 |
1993-02-21 |
Biomedical Polymers Int |
Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
|
|
US5650388A
(en)
|
1989-11-22 |
1997-07-22 |
Enzon, Inc. |
Fractionated polyalkylene oxide-conjugated hemoglobin solutions
|
|
US5312808A
(en)
|
1989-11-22 |
1994-05-17 |
Enzon, Inc. |
Fractionation of polyalkylene oxide-conjugated hemoglobin solutions
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
NL194941C
(nl)
|
1990-02-15 |
2003-08-04 |
Cordis Corp |
Werkwijze voor het aanbrengen van een fysiologisch actieve verbinding op een substraatoppervlak.
|
|
US5275838A
(en)
|
1990-02-28 |
1994-01-04 |
Massachusetts Institute Of Technology |
Immobilized polyethylene oxide star molecules for bioapplications
|
|
US5171264A
(en)
|
1990-02-28 |
1992-12-15 |
Massachusetts Institute Of Technology |
Immobilized polyethylene oxide star molecules for bioapplications
|
|
US5219564A
(en)
|
1990-07-06 |
1993-06-15 |
Enzon, Inc. |
Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
|
|
WO1992000748A1
(en)
|
1990-07-06 |
1992-01-23 |
Enzon, Inc. |
Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
|
|
FR2672053B1
(fr)
|
1991-01-30 |
1993-04-23 |
Atochem |
Polyether bloc amides, leur procede de synthese.
|
|
EP0531472B1
(en)
|
1991-03-06 |
2003-08-13 |
MERCK PATENT GmbH |
Humanized monoclonal antibodies
|
|
FR2673946B1
(fr)
|
1991-03-15 |
1993-05-28 |
Atochem |
Polyether bloc amides, leur procede de synthese.
|
|
WO1992016555A1
(en)
|
1991-03-18 |
1992-10-01 |
Enzon, Inc. |
Hydrazine containing conjugates of polypeptides and glycopolypeptides with polymers
|
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
|
US5281698A
(en)
|
1991-07-23 |
1994-01-25 |
Cetus Oncology Corporation |
Preparation of an activated polymer ester for protein conjugation
|
|
AU669124B2
(en)
|
1991-09-18 |
1996-05-30 |
Kyowa Hakko Kirin Co., Ltd. |
Process for producing humanized chimera antibody
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
GB9125979D0
(en)
|
1991-12-06 |
1992-02-05 |
Wellcome Found |
Antibody
|
|
AU660534B2
(en)
|
1992-02-13 |
1995-06-29 |
Novo Nordisk A/S |
Polyethylene or polypropylene glycol containing polymer
|
|
ATE171472T1
(de)
|
1992-02-19 |
1998-10-15 |
Schering Corp |
Klonierung und expression von humanisierten monoklonalen antikörpern gegen menschliches interleukin-4
|
|
US5686072A
(en)
|
1992-06-17 |
1997-11-11 |
Board Of Regents, The University Of Texas |
Epitope-specific monoclonal antibodies and immunotoxins and uses thereof
|
|
AU5006993A
(en)
|
1992-08-21 |
1994-03-15 |
Enzon, Inc. |
Novel attachment of polyalkylene oxides to bio-effecting substances
|
|
US5614549A
(en)
|
1992-08-21 |
1997-03-25 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US5298643A
(en)
|
1992-12-22 |
1994-03-29 |
Enzon, Inc. |
Aryl imidate activated polyalkylene oxides
|
|
US5349001A
(en)
|
1993-01-19 |
1994-09-20 |
Enzon, Inc. |
Cyclic imide thione activated polyalkylene oxides
|
|
US5321095A
(en)
|
1993-02-02 |
1994-06-14 |
Enzon, Inc. |
Azlactone activated polyalkylene oxides
|
|
US5484892A
(en)
|
1993-05-21 |
1996-01-16 |
Dana-Farber Cancer Institute, Inc. |
Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells
|
|
WO1994028937A1
(en)
|
1993-06-16 |
1994-12-22 |
Enzon, Inc. |
Conjugated biodhesives
|
|
US5965566A
(en)
|
1993-10-20 |
1999-10-12 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5840900A
(en)
|
1993-10-20 |
1998-11-24 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5880131A
(en)
|
1993-10-20 |
1999-03-09 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5605976A
(en)
|
1995-05-15 |
1997-02-25 |
Enzon, Inc. |
Method of preparing polyalkylene oxide carboxylic acids
|
|
US5643575A
(en)
|
1993-10-27 |
1997-07-01 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5919455A
(en)
|
1993-10-27 |
1999-07-06 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5446090A
(en)
|
1993-11-12 |
1995-08-29 |
Shearwater Polymers, Inc. |
Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
|
|
US5618528A
(en)
|
1994-02-28 |
1997-04-08 |
Sterling Winthrop Inc. |
Biologically compatible linear block copolymers of polyalkylene oxide and peptide units
|
|
WO1995033490A1
(en)
|
1994-06-02 |
1995-12-14 |
Enzon, Inc. |
Method of solubilizing substantially water insoluble materials
|
|
US5730990A
(en)
|
1994-06-24 |
1998-03-24 |
Enzon, Inc. |
Non-antigenic amine derived polymers and polymer conjugates
|
|
ES2251723T3
(es)
|
1994-08-12 |
2006-05-01 |
Immunomedics, Inc. |
Inmunoconjugados y anticuerpos humanizados especificos para linfoma de celulas b y celulas de leucemia.
|
|
US5824784A
(en)
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
|
US5932462A
(en)
|
1995-01-10 |
1999-08-03 |
Shearwater Polymers, Inc. |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
|
US5705154A
(en)
|
1995-03-08 |
1998-01-06 |
Schering Corporation |
Humanized monoclonal antibodies against human interleukin-4
|
|
US5756593A
(en)
|
1995-05-15 |
1998-05-26 |
Enzon, Inc. |
Method of preparing polyalkyene oxide carboxylic acids
|
|
US5672662A
(en)
|
1995-07-07 |
1997-09-30 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
|
|
US5919442A
(en)
|
1995-08-11 |
1999-07-06 |
Dendritech, Inc. |
Hyper comb-branched polymer conjugates
|
|
JPH11513669A
(ja)
|
1995-10-13 |
1999-11-24 |
アメリカ合衆国 |
ジスルフィド安定化抗体フラグメントを含む免疫毒素
|
|
ATE330644T1
(de)
|
1995-12-18 |
2006-07-15 |
Angiotech Biomaterials Corp |
Vernetzten polymerisatmassen und verfahren für ihre verwendung
|
|
US6900304B2
(en)
|
1996-01-31 |
2005-05-31 |
The Regents Of The University Of California |
Emission ratiometric indicators of phosphorylation
|
|
US8669074B2
(en)
|
1996-01-31 |
2014-03-11 |
The Regents Of The University Of California |
Chimeric phosphorylation indicator
|
|
EP0888125B1
(en)
|
1996-03-20 |
2004-05-26 |
Immunomedics, Inc. |
GLYCOSYLATED IgG ANTIBODIES
|
|
EP1731174A3
(en)
|
1996-08-02 |
2007-01-17 |
Ortho-McNeil Pharmaceutical, Inc. |
Polypeptides having a covalently bound N-terminal polyethylene glycol via hydrazone or oxime bond
|
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
EP0970227B1
(en)
|
1997-03-20 |
2008-01-09 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Recombinant antibodies and immunoconjugates targeted to cd-22 bearing cells and tumors
|
|
US6183744B1
(en)
|
1997-03-24 |
2001-02-06 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
JP3957765B2
(ja)
|
1997-04-07 |
2007-08-15 |
ジェネンテク・インコーポレイテッド |
抗ｖｅｇｆ抗体
|
|
EP2338915A3
(en)
|
1997-04-07 |
2011-10-12 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
EP0981548A4
(en)
|
1997-04-30 |
2005-11-23 |
Enzon Inc |
GLYCOSYLATABLE SINGLE CHAIN ANTIGEN-BINDING PROTEINS, MANUFACTURE AND USE THEREOF
|
|
ES2248898T3
(es)
|
1997-05-02 |
2006-03-16 |
The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services |
Inmunotoxinas que comprenden una proteina onc dirigida contra celulas malignas.
|
|
US5990237A
(en)
|
1997-05-21 |
1999-11-23 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
|
|
GB9712892D0
(en)
|
1997-06-20 |
1997-08-20 |
Eclagen Ltd |
Identification of mhc binding peptides
|
|
GB9718913D0
(en)
|
1997-09-05 |
1997-11-12 |
Glaxo Group Ltd |
Substituted oxindole derivatives
|
|
US6011042A
(en)
|
1997-10-10 |
2000-01-04 |
Enzon, Inc. |
Acyl polymeric derivatives of aromatic hydroxyl-containing compounds
|
|
US6111107A
(en)
|
1997-11-20 |
2000-08-29 |
Enzon, Inc. |
High yield method for stereoselective acylation of tertiary alcohols
|
|
US6180095B1
(en)
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
|
WO1999030727A1
(en)
|
1997-12-17 |
1999-06-24 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
|
US5985263A
(en)
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
|
US5965119A
(en)
|
1997-12-30 |
1999-10-12 |
Enzon, Inc. |
Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
|
|
DK1411075T3
(da)
|
1998-03-12 |
2008-10-27 |
Nektar Therapeutics Al Corp |
Fremgangsmåde til fremstilling af polymerkonjugater
|
|
US6153655A
(en)
|
1998-04-17 |
2000-11-28 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
|
DE69930328T2
(de)
|
1998-08-27 |
2006-12-14 |
Spirogen Ltd., Ryde |
Dimere Pyrrolobenzodiazepine
|
|
US6465612B1
(en)
|
1998-09-23 |
2002-10-15 |
The Regents Of The University Of California |
Synthetic peptides, conjugation reagents and methods
|
|
CA2375912C
(en)
|
1999-06-09 |
2014-03-11 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target b-cells
|
|
CN1284603C
(zh)
|
1999-10-08 |
2006-11-15 |
内科塔治疗亚拉巴马公司 |
杂双官能聚乙二醇衍生物和它们的制备方法
|
|
US7097840B2
(en)
|
2000-03-16 |
2006-08-29 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
US6570040B2
(en)
|
2000-03-16 |
2003-05-27 |
The Regents Of The University Of California |
Chemoselective ligation
|
|
US6911535B2
(en)
|
2000-03-22 |
2005-06-28 |
Solvlink Biosciences |
Biomolecule/polymer conjugates
|
|
US20050201981A1
(en)
|
2004-03-10 |
2005-09-15 |
Chih-Ping Liu |
Method of optimizing treatment with interferon-tau
|
|
BRPI0116728B1
(pt)
|
2001-01-05 |
2018-10-30 |
Pfizer Inc. |
anticorpos para receptor de fator de crescimento i semelhante à insulina
|
|
US7321026B2
(en)
|
2001-06-27 |
2008-01-22 |
Skytech Technology Limited |
Framework-patched immunoglobulins
|
|
CA2461351C
(en)
|
2001-09-26 |
2014-08-05 |
Ira H. Pastan |
Mutated anti-cd22 antibodies with increased affinity to cd22-expressing leukemia cells
|
|
US20040001828A1
(en)
|
2002-02-21 |
2004-01-01 |
Joseph Tuscano |
Treatment methods using anti-CD22 antibodies
|
|
GB0210121D0
(en)
|
2002-05-02 |
2002-06-12 |
Celltech R&D Ltd |
Biological products
|
|
US7456260B2
(en)
|
2002-06-17 |
2008-11-25 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Humanized antibody
|
|
AU2003264009A1
(en)
|
2002-08-15 |
2004-03-03 |
Epitomics, Inc. |
Humanized rabbit antibodies
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
US8188116B2
(en)
|
2002-09-04 |
2012-05-29 |
Vanderbilt University |
Agents for therapy efficacy monitoring and deep tissue imaging
|
|
US7754884B2
(en)
|
2005-01-03 |
2010-07-13 |
Vanderbilt University |
Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging
|
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
EP2325301B1
(en)
|
2003-02-11 |
2015-09-02 |
Shire Human Genetic Therapies, Inc. |
Diagnosis and treatment of multiple sulfatase deficiency and others using a formylglycine generating enzyme (FGE)
|
|
EP1651659A4
(en)
|
2003-08-07 |
2008-09-17 |
Epitomics Inc |
METHOD FOR HUMANIZATION OF MONOCLONAL RABBIT ANTIBODIES
|
|
EP1670804A2
(en)
|
2003-09-10 |
2006-06-21 |
GPC Biotech AG |
Heterobicyclic compounds as pharmaceutically active agents
|
|
EP1723126A2
(en)
|
2003-10-22 |
2006-11-22 |
Eli Lilly And Company |
Novel mch receptor antagonists
|
|
WO2005067546A2
(en)
|
2004-01-13 |
2005-07-28 |
Ambit Biosciences Corporation |
Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
|
|
CN1560035A
(zh)
|
2004-03-12 |
2005-01-05 |
沈阳药科大学 |
5－羟基吲哚－3－羧酸脂类衍生物
|
|
WO2005113765A2
(en)
|
2004-05-06 |
2005-12-01 |
Biomarin Pharmaceutical Inc. |
Methods of activation of sulfatases and methods and compositions of using the same
|
|
JP4806680B2
(ja)
|
2004-05-19 |
2011-11-02 |
メダレックス インコーポレイテッド |
自己犠牲リンカー及び薬剤複合体
|
|
KR20120064120A
(ko)
|
2004-06-01 |
2012-06-18 |
제넨테크, 인크. |
항체 약물 접합체 및 방법
|
|
RU2007103298A
(ru)
|
2004-06-30 |
2008-08-10 |
Новартис АГ (CH) |
Композиции и способы доставки противоопухолевых агентов
|
|
KR101270829B1
(ko)
|
2004-09-23 |
2013-06-07 |
제넨테크, 인크. |
시스테인 유전자조작 항체 및 접합체
|
|
JP4728340B2
(ja)
|
2004-10-25 |
2011-07-20 |
リガンド・ファーマシューティカルズ・インコーポレイテッド |
トロンボポエチン活性を変調する化合物および変調方法
|
|
US7255012B2
(en)
|
2004-12-01 |
2007-08-14 |
Rosemount Inc. |
Process fluid flow device with variable orifice
|
|
ES2417133T3
(es)
|
2005-02-03 |
2013-08-06 |
Antitope Limited |
Anticuerpos y proteínas humanas
|
|
CA2596925C
(en)
|
2005-02-08 |
2017-07-04 |
Km Biologics Co., Ltd. |
Method for improving expression level and stability of antibody
|
|
WO2006121820A1
(en)
|
2005-05-05 |
2006-11-16 |
Valeant Research & Development |
Phosphoramidate prodrugs for treatment of viral infection
|
|
WO2007027248A2
(en)
|
2005-05-16 |
2007-03-08 |
Valeant Research & Development |
3', 5' - cyclic nucleoside analogues for treatment of hcv
|
|
JP5171621B2
(ja)
|
2005-07-07 |
2013-03-27 |
シアトル ジェネティックス， インコーポレイテッド |
フェニルアラニン側鎖修飾をｃ末端に有するモノメチルバリン化合物
|
|
TW200745096A
(en)
|
2005-08-23 |
2007-12-16 |
Organon Nv |
Indole derivatives
|
|
EP2455382B1
(en)
|
2005-12-13 |
2016-10-26 |
Incyte Holdings Corporation |
Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
|
|
CA2644906C
(en)
|
2006-03-06 |
2016-05-10 |
Medimmune, Inc. |
Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
SI2032606T1
(sl)
*
|
2006-05-30 |
2014-02-28 |
Genentech, Inc. |
Protitelesa in imunokonjugati in njihove uporabe
|
|
ES2567402T3
(es)
|
2006-05-30 |
2016-04-22 |
Genentech, Inc. |
Anticuerpos anti CD22, sus inmunoconjugados y usos de los mismos
|
|
JP5539717B2
(ja)
|
2006-07-14 |
2014-07-02 |
塩野義製薬株式会社 |
オキシム化合物およびその使用
|
|
WO2008019303A2
(en)
|
2006-08-04 |
2008-02-14 |
Enanta Pharmaceuticals, Inc. |
Pyridazinonyl macrocyclic hepatitis c serine protease inhibitors
|
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
KR101552735B1
(ko)
|
2006-12-01 |
2015-09-14 |
메다렉스, 엘.엘.시. |
씨디22에 결합하는 인간 항체 및 이의 용도
|
|
US8729232B2
(en)
|
2008-03-27 |
2014-05-20 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
CN102348807B
(zh)
|
2009-01-12 |
2015-04-15 |
苏特罗生物制药公司 |
利用体外蛋白合成体系将非天然氨基酸引入蛋白的单装载体系
|
|
US9238878B2
(en)
|
2009-02-17 |
2016-01-19 |
Redwood Bioscience, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
WO2010117939A1
(en)
|
2009-04-06 |
2010-10-14 |
Schering Corporation |
Hcv inhibitor and therapeutic agent combinations
|
|
AR078471A1
(es)
|
2009-10-02 |
2011-11-09 |
Sanofi Aventis |
COMPUESTOS MAITANSINOIDES Y EL USO DE ESTOS PARA PREPARAR CONJUGADOS CON UN ANTICUERPO LOS CUALES SE UTILIZAN COMO AGENTES ANTICANCERIGENOS Y EL PROCEDIMIENTO DE PREPARACIoN DE ESTOS CONJUGADOS
|
|
ES2535393T3
(es)
|
2009-12-22 |
2015-05-11 |
F. Hoffmann-La Roche Ag |
Agregación dependiente de secuencia
|
|
KR20110093055A
(ko)
|
2010-02-11 |
2011-08-18 |
다우어드밴스드디스플레이머티리얼 유한회사 |
신규한 유기 발광 화합물 및 이를 채용하고 있는 유기 전계 발광 소자
|
|
AR083495A1
(es)
|
2010-10-22 |
2013-02-27 |
Esbatech Alcon Biomed Res Unit |
Anticuerpos estables y solubles
|
|
CA2819373A1
(en)
|
2010-12-09 |
2012-06-14 |
Amgen Inc. |
Bicyclic compounds as pim inhibitors
|
|
AU2012205301B2
(en)
|
2011-01-14 |
2017-01-05 |
Redwood Bioscience, Inc. |
Aldehyde-tagged immunoglobulin polypeptides and method of use thereof
|
|
US20170049906A1
(en)
|
2012-05-21 |
2017-02-23 |
President And Fellows Of Harvard College |
Translocation of non-natural chemical entities through anthrax protective antigen pore
|
|
US20140004097A1
(en)
|
2012-06-29 |
2014-01-02 |
Shire Human Genetic Therapies, Inc. |
Method of producing recombinant iduronate-2-sulfatase
|
|
KR102165464B1
(ko)
|
2012-07-19 |
2020-10-14 |
레드우드 바이오사이언스 인코포레이티드 |
Cd22에 대해 특이적인 항체 및 이들의 사용 방법
|
|
US9439972B2
(en)
|
2012-09-10 |
2016-09-13 |
Ad Lunam Labs, Inc. |
Antifungal serum
|
|
AU2013341711A1
(en)
|
2012-11-12 |
2015-05-21 |
Redwood Bioscience, Inc. |
Compounds and methods for producing a conjugate
|
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
|
SI2900277T1
(sl)
|
2012-12-13 |
2022-05-31 |
Immunomedics, Inc. |
Odmerki imunokonjugatov protiteles in SN-38 za boljšo učinkovitost in zmanjšano toksičnost
|
|
CN105722859B
(zh)
|
2013-07-25 |
2021-05-07 |
西托姆克斯治疗公司 |
多特异性抗体、多特异性可活化抗体及其使用方法
|
|
WO2015081282A1
(en)
*
|
2013-11-27 |
2015-06-04 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
|
WO2015187428A1
(en)
|
2014-06-06 |
2015-12-10 |
Redwood Bioscience, Inc. |
Anti-her2 antibody-maytansine conjugates and methods of use thereof
|
|
CA2973343C
(en)
|
2015-02-05 |
2023-08-08 |
R.P. Scherer Technologies, Llc |
Activated formylglycine-generating enzymes and methods of producing and using the same
|
|
EP4257134A3
(en)
|
2015-06-25 |
2024-01-24 |
Immunomedics, Inc. |
Combining anti-hla-dr or anti-trop-2 antibodies with microtubule inhibitors, parp inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
KR102783230B1
(ko)
|
2015-11-09 |
2025-03-19 |
알.피.쉐러 테크놀러지즈 엘엘씨 |
항-cd22 항체-메이탄신 콘쥬게이트 및 그것의 사용 방법
|
|
CA3082912A1
(en)
|
2017-12-11 |
2019-06-20 |
Triphase Accelerator U.S. Corporation |
Anti-cd22 antibody-maytansine conjugates, combinations, and methods of use thereof
|