JP2022530524A5 - - Google Patents
Info
- Publication number
- JP2022530524A5 JP2022530524A5 JP2021564298A JP2021564298A JP2022530524A5 JP 2022530524 A5 JP2022530524 A5 JP 2022530524A5 JP 2021564298 A JP2021564298 A JP 2021564298A JP 2021564298 A JP2021564298 A JP 2021564298A JP 2022530524 A5 JP2022530524 A5 JP 2022530524A5
- Authority
- JP
- Japan
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024193434A JP7844591B2 (ja) | 2019-04-29 | 2024-11-05 | バイパラトピックＦＲ－α抗体及びイムノコンジュゲート |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962840297P | 2019-04-29 | 2019-04-29 | |
| US62/840,297 | 2019-04-29 | ||
| US201962879864P | 2019-07-29 | 2019-07-29 | |
| US62/879,864 | 2019-07-29 | ||
| PCT/US2020/030245 WO2020223221A1 (en) | 2019-04-29 | 2020-04-28 | Biparatopic fr-alpha antibodies and immunoconjugates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024193434A Division JP7844591B2 (ja) | 2019-04-29 | 2024-11-05 | バイパラトピックＦＲ－α抗体及びイムノコンジュゲート |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022530524A JP2022530524A (ja) | 2022-06-29 |
| JP2022530524A5 true JP2022530524A5 (https=) | 2023-05-10 |
| JPWO2020223221A5 JPWO2020223221A5 (https=) | 2023-05-10 |
| JP7585230B2 JP7585230B2 (ja) | 2024-11-18 |
Family
ID=73028723
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021564298A Active JP7585230B2 (ja) | 2019-04-29 | 2020-04-28 | バイパラトピックＦＲ－α抗体及びイムノコンジュゲート |
| JP2024193434A Active JP7844591B2 (ja) | 2019-04-29 | 2024-11-05 | バイパラトピックＦＲ－α抗体及びイムノコンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024193434A Active JP7844591B2 (ja) | 2019-04-29 | 2024-11-05 | バイパラトピックＦＲ－α抗体及びイムノコンジュゲート |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US11396543B2 (https=) |
| EP (1) | EP3962935A4 (https=) |
| JP (2) | JP7585230B2 (https=) |
| KR (1) | KR20220004687A (https=) |
| CN (1) | CN114222756A (https=) |
| AU (1) | AU2020265568B2 (https=) |
| CA (1) | CA3138272A1 (https=) |
| IL (1) | IL287451A (https=) |
| MA (1) | MA55818A (https=) |
| SG (1) | SG11202111109UA (https=) |
| TW (2) | TWI872065B (https=) |
| WO (1) | WO2020223221A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2911499A1 (en) * | 2013-05-14 | 2014-11-20 | Immunogen, Inc. | Anti-folr1 immunoconjugate dosing regimens |
| AU2014312086B2 (en) | 2013-08-30 | 2020-03-12 | Immunogen, Inc. | Antibodies and assays for detection of folate receptor 1 |
| WO2020223221A1 (en) * | 2019-04-29 | 2020-11-05 | Immunogen, Inc. | Biparatopic fr-alpha antibodies and immunoconjugates |
| AU2022207985A1 (en) * | 2021-01-13 | 2023-07-06 | Visterra, Inc. | Humanized complement 5a receptor 1 antibodies and methods of use thereof |
| WO2022256507A1 (en) * | 2021-06-04 | 2022-12-08 | Immunogen, Inc. | Treatment of cancer in patients with soluble fr-alpha |
| KR20240159839A (ko) | 2022-03-09 | 2024-11-06 | 아스트라제네카 아베 | FRα에 대한 결합 분자 |
| TW202409080A (zh) * | 2022-07-26 | 2024-03-01 | 美商沙塔克實驗室股份有限公司 | 用於治療卵巢癌之組合療法 |
| TW202448517A (zh) | 2023-02-16 | 2024-12-16 | 瑞典商阿斯特捷利康公司 | 用治療性結合分子治療癌症的組合療法 |
| WO2025094146A1 (en) | 2023-11-02 | 2025-05-08 | Immunogen Switzerland Gmbh | Vasconstrictors for reducing ocular toxicity of antibody-maytansinoid conjugates |
| US12600795B2 (en) | 2023-12-26 | 2026-04-14 | Medicovestor, Inc. | Oligomeric IgG for immunotherapeutics and diagnostics |
| WO2025252094A1 (zh) * | 2024-06-05 | 2025-12-11 | 长春金赛药业有限责任公司 | 靶向叶酸受体α(FRα)的抗体、双特异性抗体和偶联物，及其制备和用途 |
| US20260001950A1 (en) * | 2024-07-01 | 2026-01-01 | Medicovestor, Inc. | Methods of enhancing efficacy of immunoconjugates using paired human antibodies targeted at non-overlapping b-cell epitopes on the same antigen |
| WO2026020031A2 (en) * | 2024-07-18 | 2026-01-22 | Novarock Biotherapeutics, Ltd. | Cdh17 antibodies and uses thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2556027C (en) | 2004-02-12 | 2015-11-24 | Morphotek, Inc. | Monoclonal antibodies that specifically block biological activity of a tumor antigen |
| EP2172487A1 (en) | 2005-04-22 | 2010-04-07 | Morphotek Inc. | Antibodies with Immune Effector Activity that Internalize in Folate Receptor Alpha-Positive Cells |
| EP1900752A1 (en) * | 2006-09-15 | 2008-03-19 | DOMPE' pha.r.ma s.p.a. | Human anti-folate receptor alpha antibodies and antibody fragments for the radioimmunotherapy of ovarian carcinoma |
| CN103037900B (zh) * | 2010-02-24 | 2016-04-06 | 伊缪诺金公司 | 叶酸受体1抗体与免疫缀合物以及其用途 |
| AU2011323124C1 (en) | 2010-11-05 | 2016-09-22 | Eisai Inc. | Folate receptor alpha as a diagnostic and prognostic marker for folate receptor alpha-expressing cancers |
| IL281714B2 (en) | 2011-04-01 | 2023-11-01 | Immunogen Inc | Methods for increasing the effectiveness of FOLR1 cancer therapy |
| US20120282282A1 (en) | 2011-04-04 | 2012-11-08 | Immunogen, Inc. | Methods for Decreasing Ocular Toxicity of Antibody Drug Conjugates |
| HUE049693T2 (hu) | 2012-08-31 | 2020-10-28 | Immunogen Inc | Diagnosztikai ASSAY-k és készletek a folát receptor 1 kimutatására |
| CA2911499A1 (en) | 2013-05-14 | 2014-11-20 | Immunogen, Inc. | Anti-folr1 immunoconjugate dosing regimens |
| AU2014312086B2 (en) | 2013-08-30 | 2020-03-12 | Immunogen, Inc. | Antibodies and assays for detection of folate receptor 1 |
| IL298044B2 (en) | 2013-10-08 | 2024-11-01 | Immunogen Inc | Dosing regimens of anti-FOLR1 immunoconjugate |
| EP3153178A4 (en) | 2014-06-06 | 2017-12-20 | Kyowa Hakko Kirin Co., Ltd. | Method for treating cancer patients using folr1 targeted drug and antifolate, and drug |
| CN106999604B (zh) | 2014-09-02 | 2021-08-03 | 伊缪诺金公司 | 用于配制抗体药物缀合物组合物的方法 |
| AU2016323968B2 (en) | 2015-09-17 | 2023-07-06 | Immunogen, Inc. | Therapeutic combinations comprising anti-FOLR1 immunoconjugates |
| KR20250171447A (ko) * | 2017-02-28 | 2025-12-08 | 이뮤노젠 아이엔씨 | 자기희생적 펩티드 링커 및 이들의 접합체를 갖는 메이탄시노이드 유도체 |
| GB201707864D0 (en) | 2017-05-16 | 2017-06-28 | Inst Of Cancer Research: Royal Cancer Hospital | Platinum-reistant cancer treatment |
| SG11202001348WA (en) | 2017-09-05 | 2020-03-30 | Immunogen Inc | Methods for detection of folate receptor 1 in a patient sample |
| JP2020534332A (ja) | 2017-09-22 | 2020-11-26 | イミュノジェン， インコーポレイテッド | カチオン交換クロマトグラフィーを使用した三重軽鎖抗体の分離 |
| MA51629A (fr) | 2018-01-12 | 2020-11-18 | Immunogen Inc | Procédés de production, purification et formulation de conjugués anticorps-médicaments |
| WO2020223221A1 (en) * | 2019-04-29 | 2020-11-05 | Immunogen, Inc. | Biparatopic fr-alpha antibodies and immunoconjugates |
| WO2022256507A1 (en) * | 2021-06-04 | 2022-12-08 | Immunogen, Inc. | Treatment of cancer in patients with soluble fr-alpha |
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2020
- 2020-04-28 WO PCT/US2020/030245 patent/WO2020223221A1/en not_active Ceased
- 2020-04-28 US US16/860,822 patent/US11396543B2/en active Active
- 2020-04-28 CN CN202080037442.7A patent/CN114222756A/zh active Pending
- 2020-04-28 KR KR1020217037919A patent/KR20220004687A/ko active Pending
- 2020-04-28 TW TW109114175A patent/TWI872065B/zh active
- 2020-04-28 MA MA055818A patent/MA55818A/fr unknown
- 2020-04-28 AU AU2020265568A patent/AU2020265568B2/en active Active
- 2020-04-28 TW TW113151397A patent/TW202515623A/zh unknown
- 2020-04-28 CA CA3138272A patent/CA3138272A1/en active Pending
- 2020-04-28 EP EP20798751.2A patent/EP3962935A4/en active Pending
- 2020-04-28 SG SG11202111109UA patent/SG11202111109UA/en unknown
- 2020-04-28 JP JP2021564298A patent/JP7585230B2/ja active Active
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2021
- 2021-10-20 IL IL287451A patent/IL287451A/en unknown
-
2022
- 2022-06-10 US US17/838,016 patent/US11834498B2/en active Active
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2023
- 2023-10-24 US US18/493,623 patent/US20240182560A1/en not_active Abandoned
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2024
- 2024-11-05 JP JP2024193434A patent/JP7844591B2/ja active Active
-
2025
- 2025-08-12 US US19/297,369 patent/US20260061058A1/en active Pending