JP2022518743A5 - - Google Patents
Info
- Publication number
- JP2022518743A5 JP2022518743A5 JP2021542159A JP2021542159A JP2022518743A5 JP 2022518743 A5 JP2022518743 A5 JP 2022518743A5 JP 2021542159 A JP2021542159 A JP 2021542159A JP 2021542159 A JP2021542159 A JP 2021542159A JP 2022518743 A5 JP2022518743 A5 JP 2022518743A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- alkyl
- aryl
- heterocyclyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024151730A JP2024170512A (ja) | 2019-01-23 | 2024-09-03 | 抗体－薬物コンジュゲート用のグリコシド含有ペプチドリンカー |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962795875P | 2019-01-23 | 2019-01-23 | |
| US62/795,875 | 2019-01-23 | ||
| PCT/US2020/014658 WO2020154437A1 (en) | 2019-01-23 | 2020-01-22 | Glycoside-containing peptide linkers for antibody-drug conjugates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024151730A Division JP2024170512A (ja) | 2019-01-23 | 2024-09-03 | 抗体－薬物コンジュゲート用のグリコシド含有ペプチドリンカー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022518743A JP2022518743A (ja) | 2022-03-16 |
| JP2022518743A5 true JP2022518743A5 (https=) | 2023-01-31 |
| JP7550768B2 JP7550768B2 (ja) | 2024-09-13 |
Family
ID=71736993
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021542159A Active JP7550768B2 (ja) | 2019-01-23 | 2020-01-22 | 抗体－薬物コンジュゲート用のグリコシド含有ペプチドリンカー |
| JP2024151730A Pending JP2024170512A (ja) | 2019-01-23 | 2024-09-03 | 抗体－薬物コンジュゲート用のグリコシド含有ペプチドリンカー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024151730A Pending JP2024170512A (ja) | 2019-01-23 | 2024-09-03 | 抗体－薬物コンジュゲート用のグリコシド含有ペプチドリンカー |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220226490A1 (https=) |
| EP (1) | EP3914262A4 (https=) |
| JP (2) | JP7550768B2 (https=) |
| KR (1) | KR20210119450A (https=) |
| CN (3) | CN119896746A (https=) |
| AU (1) | AU2020210919B2 (https=) |
| CA (1) | CA3127098A1 (https=) |
| WO (1) | WO2020154437A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119896746A (zh) * | 2019-01-23 | 2025-04-29 | R.P.谢勒技术有限责任公司 | 用于抗体-药物缀合物的含有糖苷的肽接头 |
| CN116783208A (zh) * | 2020-11-20 | 2023-09-19 | R.P.谢勒技术有限责任公司 | 用于抗体-药物缀合物的糖苷双裂解接头 |
| US12187810B2 (en) * | 2020-11-20 | 2025-01-07 | R.P. Scherer Technologies, Llc | Glycoside dual-cleavage linkers for antibody-drug conjugates |
| AU2022207454A1 (en) * | 2021-01-15 | 2023-06-22 | R.P. Scherer Technologies, Llc | Camptothecine antibody-drug conjugates and methods of use thereof |
| CN116847885A (zh) * | 2021-01-15 | 2023-10-03 | R.P.谢勒技术有限责任公司 | 用于抗体-药物缀合物的双切割酯接头 |
| IL305335A (en) * | 2021-02-25 | 2023-10-01 | Allygen Group | Targeted conjugates containing activator molecules and their uses |
| AU2022230398A1 (en) * | 2021-03-03 | 2023-08-31 | R.P. Scherer Technologies, Llc | Branched linkers for antibody-drug conjugates and methods of use thereof |
| US20250121090A1 (en) * | 2021-07-30 | 2025-04-17 | R.P. Scherer Technologies, Llc | Antibody-Drug Conjugates and Methods of Use Thereof |
| TW202440164A (zh) | 2022-12-13 | 2024-10-16 | 美商克林提克斯醫藥股份有限公司 | 生長抑素亞型-2受體（sst2r）靶向治療劑及其用途 |
| KR20250169306A (ko) | 2023-04-18 | 2025-12-02 | 아스트라제네카 아베 | 절단가능한 링커를 포함하는 접합체 |
| TW202525344A (zh) * | 2023-08-15 | 2025-07-01 | 瑞典商阿斯特捷利康公司 | 包含可切割連接子的軛合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2988786A4 (en) * | 2013-04-22 | 2016-12-21 | Avelas Biosciences Inc | COMPOSITIONS FOR SELECTIVE DRUG ADMINISTRATION AND METHOD OF USE |
| CN115504924A (zh) * | 2013-11-27 | 2022-12-23 | 雷德伍德生物科技股份有限公司 | 肼基-吡咯并化合物及用于生成缀合物的方法 |
| EP3373937B1 (en) * | 2015-11-09 | 2021-12-22 | R.P. Scherer Technologies, LLC | Anti-cd22 antibody-maytansine conjugates and methods of use thereof |
| US10195283B2 (en) * | 2016-03-18 | 2019-02-05 | R.P. Scherer Technologies, Llc | Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate |
| CN119367549A (zh) * | 2017-06-21 | 2025-01-28 | 芬兰吉利科斯有限公司 | 亲水性接头及其共轭物 |
| WO2019113248A1 (en) * | 2017-12-07 | 2019-06-13 | The Regents Of The University Of California | Anti-upar antibody-drug conjugates and methods of use thereof |
| CN119896746A (zh) * | 2019-01-23 | 2025-04-29 | R.P.谢勒技术有限责任公司 | 用于抗体-药物缀合物的含有糖苷的肽接头 |
-
2020
- 2020-01-22 CN CN202510154420.3A patent/CN119896746A/zh active Pending
- 2020-01-22 KR KR1020217026304A patent/KR20210119450A/ko active Pending
- 2020-01-22 AU AU2020210919A patent/AU2020210919B2/en active Active
- 2020-01-22 CN CN202080013223.5A patent/CN113874046B/zh active Active
- 2020-01-22 CN CN202510154419.0A patent/CN119896745A/zh active Pending
- 2020-01-22 US US17/423,796 patent/US20220226490A1/en active Pending
- 2020-01-22 JP JP2021542159A patent/JP7550768B2/ja active Active
- 2020-01-22 WO PCT/US2020/014658 patent/WO2020154437A1/en not_active Ceased
- 2020-01-22 EP EP20744386.2A patent/EP3914262A4/en active Pending
- 2020-01-22 CA CA3127098A patent/CA3127098A1/en active Pending
-
2024
- 2024-09-03 JP JP2024151730A patent/JP2024170512A/ja active Pending
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