JP2022534245A5 - - Google Patents
Info
- Publication number
- JP2022534245A5 JP2022534245A5 JP2021570258A JP2021570258A JP2022534245A5 JP 2022534245 A5 JP2022534245 A5 JP 2022534245A5 JP 2021570258 A JP2021570258 A JP 2021570258A JP 2021570258 A JP2021570258 A JP 2021570258A JP 2022534245 A5 JP2022534245 A5 JP 2022534245A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- independently
- polymer
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962853658P | 2019-05-28 | 2019-05-28 | |
| US62/853,658 | 2019-05-28 | ||
| US201962907458P | 2019-09-27 | 2019-09-27 | |
| US62/907,458 | 2019-09-27 | ||
| PCT/US2020/035007 WO2020243370A1 (en) | 2019-05-28 | 2020-05-28 | Polymer comprising multiple functionalized sidechains for biomolecule delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022534245A JP2022534245A (ja) | 2022-07-28 |
| JP2022534245A5 true JP2022534245A5 (https=) | 2023-06-05 |
| JP7805789B2 JP7805789B2 (ja) | 2026-01-26 |
Family
ID=71094892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021570258A Active JP7805789B2 (ja) | 2019-05-28 | 2020-05-28 | 生体分子送達のための複数の機能化側鎖を含むポリマー |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220340712A1 (https=) |
| EP (1) | EP3976015A1 (https=) |
| JP (1) | JP7805789B2 (https=) |
| KR (1) | KR20220013570A (https=) |
| AU (1) | AU2020282798A1 (https=) |
| CA (1) | CA3142035A1 (https=) |
| WO (1) | WO2020243370A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3788094A2 (en) | 2018-04-27 | 2021-03-10 | Genedit Inc. | Cationic polymer and use for biomolecule delivery |
| WO2020067142A1 (en) | 2018-09-25 | 2020-04-02 | The University Of Tokyo | Amphiphilic poly(amino acid), block copolymer using the amphiphilic poly(amino acid), and complex including the amphiphilic poly(amino acid) or the block copolymer and nucleic acid |
| US20240285781A1 (en) | 2021-06-11 | 2024-08-29 | GenEdit, Inc. | Biodegradable polymer comprising side chains with polyamine and polyalkylene oxide groups |
| WO2024020332A1 (en) * | 2022-07-18 | 2024-01-25 | Bridgeway Innovations, Llc | Oxidatively degrading and ros scavenging polymers for medical applications |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9811059D0 (en) * | 1998-05-23 | 1998-07-22 | Univ Strathclyde | Polyamino acid vesicles |
| IL131074A0 (en) * | 1999-07-23 | 2001-03-19 | Polygene Ltd | A biodegradable polycation composition for delivery of an anionic macromolecule |
| WO2010075303A1 (en) | 2008-12-23 | 2010-07-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Splicing factors with a puf protein rna-binding domain and a splicing effector domain and uses of same |
| ES2477416T3 (es) * | 2009-02-13 | 2014-07-16 | The University Of Tokyo | Poliamino�cidos cati�nicos y usos de los mismos |
| JP5661626B2 (ja) * | 2009-07-23 | 2015-01-28 | 国立大学法人 東京大学 | アニオン性ポリマー、該アニオン性ポリマーを用いたポリイオンコンプレックスおよび三元系ポリマー複合体、ならびに薬学組成物 |
| JP4655298B1 (ja) * | 2010-02-23 | 2011-03-23 | ナノキャリア株式会社 | 短鎖のカチオン性ポリアミノ酸およびその使用 |
| WO2012068627A1 (en) | 2010-11-24 | 2012-05-31 | The University Of Western Australia | Peptides for the specific binding of rna targets |
| US20120237565A1 (en) * | 2011-03-14 | 2012-09-20 | Intezyne Technologies, Incorporated | Pegylated polyplexes containing two or more different polymers for polynucleotide delivery |
| AU2013248928A1 (en) | 2012-04-16 | 2014-12-04 | The State Board Of Higher Education On Behalf Of The University Of Oregon | Peptides for the binding of nucleotide targets |
| CN113355357B (zh) | 2012-12-12 | 2024-12-03 | 布罗德研究所有限公司 | 对用于序列操纵的改进的系统、方法和酶组合物进行的工程化和优化 |
| EP2840140B2 (en) | 2012-12-12 | 2023-02-22 | The Broad Institute, Inc. | Crispr-Cas based method for mutation of prokaryotic cells |
| US20140310830A1 (en) | 2012-12-12 | 2014-10-16 | Feng Zhang | CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| WO2014093655A2 (en) | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains |
| IL239344B2 (en) | 2012-12-12 | 2024-06-01 | Broad Inst Inc | Systems engineering, methods and optimal guiding components for sequence manipulation |
| US20180237800A1 (en) * | 2015-09-21 | 2018-08-23 | The Regents Of The University Of California | Compositions and methods for target nucleic acid modification |
| WO2017056095A1 (en) * | 2015-09-30 | 2017-04-06 | Ramot At Tel-Aviv University Ltd. | Polyaminated polyglutamic acid-containing compounds and uses thereof for delivering oligonucleotides |
| WO2018094356A2 (en) * | 2016-11-18 | 2018-05-24 | Genedit Inc. | Compositions and methods for target nucleic acid modification |
| WO2021217082A1 (en) * | 2020-04-23 | 2021-10-28 | Genedit Inc. | Polymer with cationic and hydrophobic side chains |
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2020
- 2020-05-28 US US17/614,307 patent/US20220340712A1/en active Pending
- 2020-05-28 JP JP2021570258A patent/JP7805789B2/ja active Active
- 2020-05-28 EP EP20733170.3A patent/EP3976015A1/en active Pending
- 2020-05-28 WO PCT/US2020/035007 patent/WO2020243370A1/en not_active Ceased
- 2020-05-28 KR KR1020217042746A patent/KR20220013570A/ko not_active Ceased
- 2020-05-28 CA CA3142035A patent/CA3142035A1/en active Pending
- 2020-05-28 AU AU2020282798A patent/AU2020282798A1/en active Pending