JP2020514299A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020514299A5 JP2020514299A5 JP2019536976A JP2019536976A JP2020514299A5 JP 2020514299 A5 JP2020514299 A5 JP 2020514299A5 JP 2019536976 A JP2019536976 A JP 2019536976A JP 2019536976 A JP2019536976 A JP 2019536976A JP 2020514299 A5 JP2020514299 A5 JP 2020514299A5
- Authority
- JP
- Japan
- Prior art keywords
- chemical formula
- solvate
- hydrate
- structure represented
- following chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(C)C*C(*)(*)SSC*(*)C*CN(*)CIC(CON)CON Chemical compound CC(C)C*C(*)(*)SSC*(*)C*CN(*)CIC(CON)CON 0.000 description 3
- ANZUADGNOKSXOB-UHFFFAOYSA-N CCOc1ccc(C(CC2)C(CC3)C(CC4)C2(C)C4OCCCOC(C(F)(F)F)(C(F)(F)F)C(F)(F)F)c3c1 Chemical compound CCOc1ccc(C(CC2)C(CC3)C(CC4)C2(C)C4OCCCOC(C(F)(F)F)(C(F)(F)F)C(F)(F)F)c3c1 ANZUADGNOKSXOB-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762443822P | 2017-01-09 | 2017-01-09 | |
| US62/443,822 | 2017-01-09 | ||
| PCT/IL2018/050031 WO2018127927A1 (en) | 2017-01-09 | 2018-01-09 | Compounds and methods for trans-membrane delivery of molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020514299A JP2020514299A (ja) | 2020-05-21 |
| JP2020514299A5 true JP2020514299A5 (https=) | 2021-02-18 |
| JP7348064B2 JP7348064B2 (ja) | 2023-09-20 |
Family
ID=62789169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019536976A Active JP7348064B2 (ja) | 2017-01-09 | 2018-01-09 | 分子を経膜送達するための化合物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11230710B2 (https=) |
| EP (1) | EP3565603B1 (https=) |
| JP (1) | JP7348064B2 (https=) |
| KR (1) | KR20190104392A (https=) |
| CN (1) | CN110402152B (https=) |
| AU (1) | AU2018205898B2 (https=) |
| CA (1) | CA3049640A1 (https=) |
| EA (1) | EA201991661A1 (https=) |
| IL (1) | IL267919B2 (https=) |
| WO (1) | WO2018127927A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11318206B2 (en) | 2014-03-28 | 2022-05-03 | Aposense Ltd | Compounds and methods for trans-membrane delivery of molecules |
| WO2018127927A1 (en) | 2017-01-09 | 2018-07-12 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| US10195286B2 (en) * | 2017-07-04 | 2019-02-05 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| WO2019130319A1 (en) * | 2018-01-01 | 2019-07-04 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| WO2020044349A1 (en) * | 2018-08-30 | 2020-03-05 | Aposense Ltd. | Compounds, cojugates and compositions for use in the methods for trans-membrane delivery of molecules |
| WO2023022055A1 (ja) * | 2021-08-17 | 2023-02-23 | 国立大学法人東海国立大学機構 | 修飾ポリヌクレオチド |
| WO2025096244A1 (en) * | 2023-10-30 | 2025-05-08 | Olfera Corporation | Olfactory delivery scaffolds and methods for making and using same |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997040679A1 (en) | 1996-05-01 | 1997-11-06 | Imarx Pharmaceutical Corp. | Methods for delivering compounds into a cell |
| US6090800A (en) | 1997-05-06 | 2000-07-18 | Imarx Pharmaceutical Corp. | Lipid soluble steroid prodrugs |
| WO1998050041A1 (en) | 1997-05-06 | 1998-11-12 | Imarx Pharmaceutical Corp. | Novel prodrugs comprising fluorinated amphiphiles |
| FR2846969A1 (fr) | 2002-11-08 | 2004-05-14 | Salles Jean Pierre | Nouveaux vecteurs moleculaires amphiphiles fluorocarbones a usage biomedical et medical |
| SE527131C2 (sv) | 2004-02-13 | 2005-12-27 | Innoventus Project Ab | Steroider för cancerbehandling |
| WO2006006156A2 (en) | 2004-07-08 | 2006-01-19 | Nst Neurosurvival Technologies Ltd | Compounds/methods for detection of medical disorders |
| KR20070053214A (ko) * | 2004-08-26 | 2007-05-23 | 니콜라스 피라말 인디아 리미티드 | 신규 생분해성 링커를 함유하는 프로드럭 |
| NZ554176A (en) | 2004-10-01 | 2010-04-30 | Prometic Biosciences Inc | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
| RU2408605C2 (ru) | 2005-02-18 | 2011-01-10 | Анджиокем Инк. | Полипептид, способный преодолевать гематоэнцефалический барьер, и его конъюгат |
| AU2007299705B2 (en) | 2006-09-22 | 2012-09-06 | Dharmacon, Inc. | Duplex oligonucleotide complexes and methods for gene silencing by RNA interference |
| WO2009073809A2 (en) | 2007-12-04 | 2009-06-11 | Alnylam Pharmaceuticals, Inc. | Carbohydrate conjugates as delivery agents for oligonucleotides |
| CA2972694C (en) | 2008-05-13 | 2020-02-11 | University Of Washington | Diblock copolymers and polynucleotide complexes thereof for delivery into cells |
| WO2009155335A2 (en) | 2008-06-19 | 2009-12-23 | University Of Maryland, Baltimore | Conjugates of 19f mr imaging tracers and chemotherapeutic agents for drug quantification and drug dose individualization |
| EP2342340A1 (en) | 2008-09-22 | 2011-07-13 | Rxi Pharmaceuticals Corporation | Rna interference in skin indications |
| US20120035362A1 (en) | 2010-08-03 | 2012-02-09 | Berry And Associates, Inc. | Phosphoramidite derivatives of folic acid |
| GB201122458D0 (en) | 2011-12-30 | 2012-02-08 | Univ Wageningen | Modified cascade ribonucleoproteins and uses thereof |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| CA2876860A1 (en) | 2012-05-30 | 2013-12-05 | Baylor College Of Medicine | Supercoiled minivectors as a tool for dna repair, alteration and replacement |
| BR112015008365A2 (pt) | 2012-10-16 | 2017-07-04 | Endocyte Inc | composto da fórmula b-l(d)x, ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto, composição de forma de dosagem unitária ou dose unitária, composição para tratar um câncer em um paciente, e método para tratar um câncer em um paciente |
| WO2014127052A1 (en) | 2013-02-13 | 2014-08-21 | Zondlo Neal | Perfluoro-tert-butyl hydroxyproline |
| AU2014348212C1 (en) | 2013-11-18 | 2018-11-29 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| US9889202B2 (en) | 2014-03-28 | 2018-02-13 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| US9993563B2 (en) | 2014-03-28 | 2018-06-12 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| CA2944141C (en) * | 2014-03-28 | 2023-03-28 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| US20160016855A1 (en) * | 2014-07-21 | 2016-01-21 | Benxin Wu | Fabrication of carbon nanotube-nonoxide structural ceramic nanocomposites through laser sintering |
| WO2018127927A1 (en) | 2017-01-09 | 2018-07-12 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| US10195286B2 (en) | 2017-07-04 | 2019-02-05 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
-
2018
- 2018-01-09 WO PCT/IL2018/050031 patent/WO2018127927A1/en not_active Ceased
- 2018-01-09 IL IL267919A patent/IL267919B2/en unknown
- 2018-01-09 CA CA3049640A patent/CA3049640A1/en active Pending
- 2018-01-09 EA EA201991661A patent/EA201991661A1/ru unknown
- 2018-01-09 JP JP2019536976A patent/JP7348064B2/ja active Active
- 2018-01-09 US US16/476,557 patent/US11230710B2/en active Active
- 2018-01-09 CN CN201880017053.0A patent/CN110402152B/zh active Active
- 2018-01-09 AU AU2018205898A patent/AU2018205898B2/en active Active
- 2018-01-09 KR KR1020197023505A patent/KR20190104392A/ko not_active Withdrawn
- 2018-01-09 EP EP18736287.6A patent/EP3565603B1/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020514299A5 (https=) | ||
| JP7075669B2 (ja) | 核酸送達用カチオン性脂質及びその調製物 | |
| JP2022505234A5 (https=) | ||
| Mével et al. | DODAG; a versatile new cationic lipid that mediates efficient delivery of pDNA and siRNA | |
| JP2017061563A5 (https=) | ||
| JP2019514426A5 (https=) | ||
| ES2987915T3 (es) | Nuevos lípidos catiónicos de bajo peso molecular para el suministro de oligonucleótidos | |
| JP2016153410A5 (https=) | ||
| BR112013016761B1 (pt) | Uso de um composto, composto e composição farmacêutica | |
| JP2010521485A5 (https=) | ||
| JP2012518029A5 (https=) | ||
| JP2022502451A (ja) | 核酸送達のための脂質化カチオン性ペプチド化合物を含む脂質ナノ粒子製剤 | |
| JP2020525502A5 (https=) | ||
| CN114945556B (zh) | 用于核酸转染的类脂质及其用途 | |
| JP2003511045A (ja) | Ｒｎａ結合化合物の同定方法 | |
| CN114681621A (zh) | 肽寡核苷酸缀合物 | |
| AU2019260738B2 (en) | Integrin targeting ligands and uses thereof | |
| AU2018370019B2 (en) | Stable compositions of pegylated carfilzomib compounds | |
| JP2021502346A5 (https=) | ||
| JP2016535058A5 (https=) | ||
| JPWO2021049504A5 (https=) | ||
| JP2013537404A5 (https=) | ||
| CN117529490A (zh) | 用于将药物递送至肝细胞的环状肽-N-乙酰半乳糖胺（GalNAc）缀合物 | |
| JP2018527360A5 (https=) | ||
| US20130079383A1 (en) | Lipid Compounds Targeting VLA-4 |