JP2018527360A5 - - Google Patents
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- Publication number
- JP2018527360A5 JP2018527360A5 JP2018512334A JP2018512334A JP2018527360A5 JP 2018527360 A5 JP2018527360 A5 JP 2018527360A5 JP 2018512334 A JP2018512334 A JP 2018512334A JP 2018512334 A JP2018512334 A JP 2018512334A JP 2018527360 A5 JP2018527360 A5 JP 2018527360A5
- Authority
- JP
- Japan
- Prior art keywords
- moiety
- compound according
- protein
- compound
- alkylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562222059P | 2015-09-22 | 2015-09-22 | |
| US62/222,059 | 2015-09-22 | ||
| PCT/US2016/052829 WO2017053391A1 (en) | 2015-09-22 | 2016-09-21 | Modified cytotoxins and their therapeutic use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018527360A JP2018527360A (ja) | 2018-09-20 |
| JP2018527360A5 true JP2018527360A5 (https=) | 2019-10-31 |
Family
ID=58276138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018512334A Pending JP2018527360A (ja) | 2015-09-22 | 2016-09-21 | 修飾された細胞毒とその治療的使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10023581B2 (https=) |
| EP (1) | EP3353159A4 (https=) |
| JP (1) | JP2018527360A (https=) |
| KR (1) | KR20180045001A (https=) |
| CN (1) | CN108368075A (https=) |
| AU (1) | AU2016326392B2 (https=) |
| CA (1) | CA2998528A1 (https=) |
| HK (1) | HK1254461A1 (https=) |
| IL (1) | IL257932A (https=) |
| MX (1) | MX380314B (https=) |
| MY (1) | MY193776A (https=) |
| RU (1) | RU2721949C2 (https=) |
| WO (1) | WO2017053391A1 (https=) |
| ZA (1) | ZA201801482B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2998528A1 (en) * | 2015-09-22 | 2017-03-30 | The Regents Of The University Of California | Modified cytotoxins and their therapeutic use |
| US10286079B2 (en) | 2015-09-22 | 2019-05-14 | The Regents Of The University Of California | Modified cytotoxins and their therapeutic use |
| AU2018237139A1 (en) * | 2017-03-22 | 2019-10-17 | The Regents Of The University Of California | Modified oligonucleotides and therapeutic uses thereof |
| WO2021007322A1 (en) * | 2019-07-09 | 2021-01-14 | Northwestern University | Methods of using modified cytotoxins to treat cancer |
| IT202100025172A1 (it) | 2021-09-30 | 2023-03-30 | Indena Spa | Processo per la preparazione di derivati tassanici |
| KR20250057244A (ko) | 2023-10-20 | 2025-04-29 | (주)블루엔씨 | 고정밀 3d 프린팅 기반 금형 제작 방법 및 장치 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5411984A (en) | 1992-10-16 | 1995-05-02 | Virginia Tech Intellectual Properties, Inc. | Water soluble analogs and prodrugs of taxol |
| AU6803494A (en) * | 1993-06-07 | 1995-01-03 | British Technology Group Limited | Anticancer compounds |
| US5534499A (en) | 1994-05-19 | 1996-07-09 | The University Of British Columbia | Lipophilic drug derivatives for use in liposomes |
| AU735205B2 (en) | 1997-05-16 | 2001-07-05 | Commonwealth Scientific And Industrial Research Organisation | Vaccine and assay |
| US5981564A (en) * | 1998-07-01 | 1999-11-09 | Universite Laval | Water-soluble derivatives of paclitaxel, method for producing same and uses thereof |
| AU2002953095A0 (en) * | 2002-11-29 | 2002-12-19 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| NO319551B1 (no) | 2003-07-04 | 2005-08-29 | Thia Medica As | Proteinmateriale fra enkeltceller |
| GB0321613D0 (en) | 2003-09-15 | 2003-10-15 | Drug Discovery Lab As | Compounds |
| KR101241862B1 (ko) | 2003-09-19 | 2013-03-13 | 노보 노르디스크 에이/에스 | 신규 glp-1 유도체 |
| RU2340616C2 (ru) * | 2003-10-29 | 2008-12-10 | Сонус Фармасьютикалз, Инк. | Токоферол-модифицированные терапевтические лекарственные соединения |
| GB0412181D0 (en) * | 2004-06-01 | 2004-06-30 | Celltech R&D Ltd | Biological products |
| EP1804838A2 (en) * | 2004-09-15 | 2007-07-11 | Drug Discovery Laboratory AS | Drug conjugates of long chain fatty acid or ester moieties as protein binding prodrugs |
| JP5755398B2 (ja) | 2005-03-18 | 2015-07-29 | ノヴォ ノルディスク アー/エス | 伸長されたglp−1化合物 |
| TW200731991A (en) * | 2005-12-20 | 2007-09-01 | Sonus Pharma Inc | Lipophilic di(anticancer drug) compounds, compositions and related methods |
| KR20100126361A (ko) | 2008-02-08 | 2010-12-01 | 에일러론 테라퓨틱스 인코포레이티드 | 치료용 펩티드유사 거대고리 |
| MX2010011165A (es) * | 2008-04-10 | 2011-02-22 | Abraxis Bioscience Llc | Composiciones de derivados de taxano hidrofobos y sus usos. |
| WO2010107487A2 (en) | 2009-03-18 | 2010-09-23 | Wu Nian | Lipid-drug conjugates for drug delivery |
| EP2413937A1 (en) | 2009-04-02 | 2012-02-08 | Shire LLC | Novel dicarboxylic acid linked amino acid and peptide prodrugs of opioids and uses thereof |
| WO2011085000A2 (en) | 2010-01-06 | 2011-07-14 | The University Of North Carolina At Chapel Hill | Fatty acid derivatives and analogs of drugs |
| CN118767117A (zh) | 2010-01-22 | 2024-10-15 | 诺沃—诺迪斯克保健股份有限公司 | 体内功效延长的生长激素 |
| JP5980689B2 (ja) | 2010-01-22 | 2016-08-31 | ノヴォ・ノルディスク・ヘルス・ケア・アーゲー | 安定な成長ホルモン化合物 |
| EP2536434B1 (en) | 2010-02-16 | 2016-04-20 | Novo Nordisk A/S | Purification method |
| RU2012151134A (ru) * | 2010-05-10 | 2014-06-20 | Дзе Реджентс Оф Дзе Юниверсити Оф Калифорния | Логометрическая комбинаторная доставка лекарственных средств |
| EP2392324A1 (en) * | 2010-06-01 | 2011-12-07 | Societe De Coordination De Recherches Therapeutiques | Rhenium complexes and their pharmaceutical use |
| ES2630031T3 (es) | 2010-09-28 | 2017-08-17 | Aegerion Pharmaceuticals, Inc. | Un polipéptido de leptina pinnípedo-humano quimérico con solubilidad aumentada |
| WO2012050923A2 (en) | 2010-09-28 | 2012-04-19 | Amylin Pharmaceuticals, Inc. | Engineered polypeptides having enhanced duration of action |
| WO2012048204A2 (en) * | 2010-10-08 | 2012-04-12 | Virginia Commonwealth University | Prodrugs utilizing a transporter directed uptake mechanism |
| BR112013033239A2 (pt) | 2011-06-22 | 2016-09-06 | Vyome Biosciences | pró-farmácos de conjugado baseado em atifungicos e antibacterianos |
| JP6006309B2 (ja) | 2011-07-08 | 2016-10-12 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド |
| ES2732475T3 (es) | 2011-07-08 | 2019-11-22 | Aegerion Pharmaceuticals Inc | Polipéptidos modificados por ingeniería genética que tienen una duración potenciada de la acción y una inmunogenicidad reducida |
| KR101435261B1 (ko) | 2012-07-23 | 2014-09-02 | 아주대학교산학협력단 | 항암제-링커-알부민 결합체, 이의 제조방법 및 상기 결합체를 포함하는 약물 전달용 조성물 |
| EP2922817A4 (en) * | 2012-11-21 | 2016-06-22 | Univ Sydney | OMEGA-3 Analogs |
| US9962452B2 (en) * | 2013-02-04 | 2018-05-08 | Zhuhai Beihai Biotech Co., Ltd. | Soluble complexes of drug analogs and albumin |
| US20160115192A1 (en) * | 2013-06-10 | 2016-04-28 | Cedars-Sinai Medical Center | Antioxidant, anti-inflammatory and anticancer derivatives of triptolide and nanospheres thereof |
| CN112043835B (zh) | 2013-12-06 | 2022-10-21 | 韩捷 | 用于含氮和羟基的药物的生物可逆引入基团 |
| CN107708702A (zh) * | 2014-11-17 | 2018-02-16 | 塞勒克塔生物科学有限公司 | 磷脂醚类似物作为靶向癌症的药物载体 |
| CN104478813A (zh) * | 2014-12-20 | 2015-04-01 | 苏州博源医疗科技有限公司 | 5-氟尿嘧啶衍生物、5-氟尿嘧啶免疫原及其抗体与5-氟尿嘧啶检测试剂盒 |
| CA2998528A1 (en) * | 2015-09-22 | 2017-03-30 | The Regents Of The University Of California | Modified cytotoxins and their therapeutic use |
| US10286079B2 (en) * | 2015-09-22 | 2019-05-14 | The Regents Of The University Of California | Modified cytotoxins and their therapeutic use |
| US20200048198A1 (en) * | 2017-03-22 | 2020-02-13 | The Regents Of The University Of California | Modified histone deacetylase inhibitors and uses thereof |
| WO2018175622A1 (en) * | 2017-03-22 | 2018-09-27 | The Regents Of The University Of California | Modified anthracycline compounds and their therapeutic use |
| WO2018175601A1 (en) * | 2017-03-22 | 2018-09-27 | The Regents Of The University Of California | Modified platinum compounds and therapeutic uses thereof |
| US20200046859A1 (en) * | 2017-04-27 | 2020-02-13 | The Regents Of The University Of California | Modified mri contrast agents and uses thereof |
-
2016
- 2016-09-21 CA CA2998528A patent/CA2998528A1/en not_active Abandoned
- 2016-09-21 HK HK18113547.1A patent/HK1254461A1/zh unknown
- 2016-09-21 MX MX2018002514A patent/MX380314B/es unknown
- 2016-09-21 EP EP16849481.3A patent/EP3353159A4/en not_active Withdrawn
- 2016-09-21 KR KR1020187008860A patent/KR20180045001A/ko not_active Withdrawn
- 2016-09-21 CN CN201680054455.9A patent/CN108368075A/zh active Pending
- 2016-09-21 WO PCT/US2016/052829 patent/WO2017053391A1/en not_active Ceased
- 2016-09-21 US US15/271,822 patent/US10023581B2/en active Active
- 2016-09-21 JP JP2018512334A patent/JP2018527360A/ja active Pending
- 2016-09-21 RU RU2018107843A patent/RU2721949C2/ru active
- 2016-09-21 MY MYPI2018000369A patent/MY193776A/en unknown
- 2016-09-21 AU AU2016326392A patent/AU2016326392B2/en not_active Expired - Fee Related
-
2018
- 2018-03-02 ZA ZA2018/01482A patent/ZA201801482B/en unknown
- 2018-03-06 IL IL257932A patent/IL257932A/en unknown
- 2018-04-04 US US15/945,285 patent/US10654864B2/en active Active - Reinstated
-
2020
- 2020-04-09 US US16/844,627 patent/US20210047338A1/en not_active Abandoned
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