JP2023531444A5 - - Google Patents

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Publication number
JP2023531444A5
JP2023531444A5 JP2022578631A JP2022578631A JP2023531444A5 JP 2023531444 A5 JP2023531444 A5 JP 2023531444A5 JP 2022578631 A JP2022578631 A JP 2022578631A JP 2022578631 A JP2022578631 A JP 2022578631A JP 2023531444 A5 JP2023531444 A5 JP 2023531444A5
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JP
Japan
Prior art keywords
polyplex
substituted
amine
polymer
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022578631A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023531444A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/034462 external-priority patent/WO2021257262A1/en
Publication of JP2023531444A publication Critical patent/JP2023531444A/ja
Publication of JP2023531444A5 publication Critical patent/JP2023531444A5/ja
Priority to JP2025163591A priority Critical patent/JP2026003134A/ja
Pending legal-status Critical Current

Links

JP2022578631A 2020-06-19 2021-05-27 改変された末端基および増強された肺送達を有するポリ（アミン－ｃｏ－エステル）ポリマー Pending JP2023531444A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025163591A JP2026003134A (ja) 2020-06-19 2025-09-30 改変された末端基および増強された肺送達を有するポリ（アミン－ｃｏ－エステル）ポリマー

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063041739P 2020-06-19 2020-06-19
US63/041,739 2020-06-19
PCT/US2021/034462 WO2021257262A1 (en) 2020-06-19 2021-05-27 Poly(amine-co-ester) polymers with modified end groups and enhanced pulmonary delivery

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025163591A Division JP2026003134A (ja) 2020-06-19 2025-09-30 改変された末端基および増強された肺送達を有するポリ（アミン－ｃｏ－エステル）ポリマー

Publications (2)

Publication Number Publication Date
JP2023531444A JP2023531444A (ja) 2023-07-24
JP2023531444A5 true JP2023531444A5 (https=) 2024-06-04

Family

ID=76859713

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022578631A Pending JP2023531444A (ja) 2020-06-19 2021-05-27 改変された末端基および増強された肺送達を有するポリ（アミン－ｃｏ－エステル）ポリマー
JP2025163591A Pending JP2026003134A (ja) 2020-06-19 2025-09-30 改変された末端基および増強された肺送達を有するポリ（アミン－ｃｏ－エステル）ポリマー

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025163591A Pending JP2026003134A (ja) 2020-06-19 2025-09-30 改変された末端基および増強された肺送達を有するポリ（アミン－ｃｏ－エステル）ポリマー

Country Status (10)

Country Link
US (1) US12558429B2 (https=)
EP (1) EP4168471A1 (https=)
JP (2) JP2023531444A (https=)
KR (1) KR20230042018A (https=)
CN (1) CN116157444A (https=)
AU (1) AU2021293780A1 (https=)
BR (1) BR112022025855A2 (https=)
CA (1) CA3183351A1 (https=)
MX (1) MX2022016581A (https=)
WO (1) WO2021257262A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11814464B2 (en) 2019-04-29 2023-11-14 Yale University Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof
AU2021293780A1 (en) 2020-06-19 2023-02-02 Yale University Poly(amine-co-ester) polymers with modified end groups and enhanced pulmonary delivery
JP2024545093A (ja) * 2021-12-08 2024-12-05 イェール ユニバーシティー 細胞および組織に標的化するためのポリ（アミン－ｃｏ－エステル）ナノ粒子への表面コンジュゲーション
WO2023159189A1 (en) * 2022-02-18 2023-08-24 Yale University Branched poly(amine-co-ester) polymers for more efficient nucleic expression
CN114874422B (zh) * 2022-06-16 2023-05-12 上海云沂生物医药科技有限公司 一种聚烷基胺、其合成方法、颗粒及用途
EP4324485A1 (en) * 2022-08-15 2024-02-21 Branca Banus Ltd A method for the production of pegylated hyperbranched poly( -amino ester)s, pegylated hyperbranched poly( -amino ester)s produced by those methods and their use in enhanced nucleic acid delivery
WO2024103225A1 (zh) * 2022-11-14 2024-05-23 林桂孜 一种阳离子聚酯及其制备方法和应用
EP4725977A1 (en) * 2023-06-08 2026-04-15 Integena Inc Efficient cationic polyester and use thereof
CN119490670A (zh) * 2024-11-26 2025-02-21 山东大学 一种慢病毒转染增强纳米颗粒及其制备方法与应用

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