JP2025176137A5 - - Google Patents
Info
- Publication number
- JP2025176137A5 JP2025176137A5 JP2025151940A JP2025151940A JP2025176137A5 JP 2025176137 A5 JP2025176137 A5 JP 2025176137A5 JP 2025151940 A JP2025151940 A JP 2025151940A JP 2025151940 A JP2025151940 A JP 2025151940A JP 2025176137 A5 JP2025176137 A5 JP 2025176137A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- independently
- carbons
- membered ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063118568P | 2020-11-25 | 2020-11-25 | |
| US63/118,568 | 2020-11-25 | ||
| PCT/US2021/060763 WO2022115563A1 (en) | 2020-11-25 | 2021-11-24 | Extended release hydrogel conjugates of c-natriuretic peptides |
| JP2023531536A JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Division JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025176137A JP2025176137A (ja) | 2025-12-03 |
| JP2025176137A5 true JP2025176137A5 (https=) | 2026-01-05 |
Family
ID=81754916
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Active JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
| JP2025151940A Pending JP2025176137A (ja) | 2020-11-25 | 2025-09-12 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Active JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240041982A1 (https=) |
| EP (1) | EP4251150A4 (https=) |
| JP (2) | JP7837333B2 (https=) |
| CN (1) | CN116635027A (https=) |
| WO (1) | WO2022115563A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023110758A1 (en) | 2021-12-13 | 2023-06-22 | Ascendis Pharma Growth Disorders A/S | Effective doses of cnp conjugates |
| EP4529454A1 (en) | 2022-05-23 | 2025-04-02 | Ascendis Pharma Growth Disorders A/S | Liquid pharmaceutical formulations of cnp compounds |
| WO2024104922A1 (en) | 2022-11-14 | 2024-05-23 | Ascendis Pharma Growth Disorders A/S | Method of improving skeletal muscle function |
| AU2024240722A1 (en) | 2023-03-20 | 2025-09-18 | Ascendis Pharma Growth Disorders A/S | Method of treatment of a thoracolumbar deformity in a human subject with achondroplasia |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2373680C (en) * | 1999-05-17 | 2008-07-29 | Conjuchem Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
| EP2334335A1 (en) * | 2008-09-19 | 2011-06-22 | Nektar Therapeutics | Polymer conjugates of cd-np peptides |
| PT2432489T (pt) * | 2009-05-20 | 2016-12-07 | Biomarin Pharm Inc | Variantes do péptido natriurético de tipo c |
| CA2848142C (en) * | 2011-09-07 | 2021-05-18 | Prolynx Llc | Hydrogels with biodegradable crosslinking |
| EP3242689A1 (en) * | 2015-01-09 | 2017-11-15 | Ascendis Pharma Growth Disorders A/S | Cnp prodrugs |
| HUE057083T2 (hu) * | 2015-12-08 | 2022-04-28 | Biomarin Pharm Inc | C-típusú nátriuretikus peptid változatainak alkalmazása oszteoartritisz kezelésére |
| WO2017118700A1 (en) * | 2016-01-08 | 2017-07-13 | Ascendis Pharma Growth Disorders A/S | Controlled-release cnp agonists with increased nep stability |
| DK3400019T3 (da) * | 2016-01-08 | 2022-10-24 | Ascendis Pharma Growth Disorders As | CNP-prodrugs med bærerbinding ved ringenheden |
| IL259827B2 (en) * | 2016-01-08 | 2025-07-01 | Ascendis Pharma Growth Disorders As | Controlled-release CNP agonists with low initial NPR-B activity |
| KR20180129825A (ko) * | 2016-03-16 | 2018-12-05 | 프로린크스 엘엘시 | 엑세나타이드 유사체의 연장된 방출 컨쥬게이트 |
| US11896671B2 (en) * | 2016-07-13 | 2024-02-13 | Ascendis Pharma A/S | Conjugation method for carrier-linked prodrugs |
| CN119970617A (zh) * | 2019-04-05 | 2025-05-13 | 普罗林科斯有限责任公司 | 改良偶联接头 |
| CN114126638A (zh) * | 2019-04-26 | 2022-03-01 | 普罗林科斯有限责任公司 | 缓慢释放的细胞因子偶联物 |
-
2021
- 2021-11-24 WO PCT/US2021/060763 patent/WO2022115563A1/en not_active Ceased
- 2021-11-24 US US18/038,687 patent/US20240041982A1/en active Pending
- 2021-11-24 EP EP21899093.5A patent/EP4251150A4/en active Pending
- 2021-11-24 JP JP2023531536A patent/JP7837333B2/ja active Active
- 2021-11-24 CN CN202180079063.9A patent/CN116635027A/zh active Pending
-
2025
- 2025-09-12 JP JP2025151940A patent/JP2025176137A/ja active Pending
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