JP2025176137A5 - - Google Patents
Info
- Publication number
- JP2025176137A5 JP2025176137A5 JP2025151940A JP2025151940A JP2025176137A5 JP 2025176137 A5 JP2025176137 A5 JP 2025176137A5 JP 2025151940 A JP2025151940 A JP 2025151940A JP 2025151940 A JP2025151940 A JP 2025151940A JP 2025176137 A5 JP2025176137 A5 JP 2025176137A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- independently
- carbons
- membered ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063118568P | 2020-11-25 | 2020-11-25 | |
| US63/118,568 | 2020-11-25 | ||
| PCT/US2021/060763 WO2022115563A1 (en) | 2020-11-25 | 2021-11-24 | Extended release hydrogel conjugates of c-natriuretic peptides |
| JP2023531536A JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Division JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025176137A JP2025176137A (ja) | 2025-12-03 |
| JP2025176137A5 true JP2025176137A5 (https=) | 2026-01-05 |
Family
ID=81754916
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Active JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
| JP2025151940A Pending JP2025176137A (ja) | 2020-11-25 | 2025-09-12 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Active JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240041982A1 (https=) |
| EP (1) | EP4251150A4 (https=) |
| JP (2) | JP7837333B2 (https=) |
| CN (1) | CN116635027A (https=) |
| WO (1) | WO2022115563A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3236278A1 (en) | 2021-12-13 | 2023-06-22 | Kennett Sprogoe | Effective doses of cnp conjugates |
| IL316466A (en) | 2022-05-23 | 2024-12-01 | Ascendis Pharma Growth Disorders As | Liquid pharmaceutical formulations of cnp compounds |
| WO2024104922A1 (en) | 2022-11-14 | 2024-05-23 | Ascendis Pharma Growth Disorders A/S | Method of improving skeletal muscle function |
| AU2024240722A1 (en) | 2023-03-20 | 2025-09-18 | Ascendis Pharma Growth Disorders A/S | Method of treatment of a thoracolumbar deformity in a human subject with achondroplasia |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1105409E (pt) * | 1999-05-17 | 2006-07-31 | Conjuchem Inc | Proteccao de peptidos terapeuticos endogenos da actividade de peptidases por conjugacao a componentes do sangue |
| WO2010033216A1 (en) * | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Polymer conjugates of nesiritide peptides |
| ES2608457T3 (es) * | 2009-05-20 | 2017-04-11 | Biomarin Pharmaceutical Inc. | Variantes de péptido natriurético de tipo C |
| KR102109067B1 (ko) * | 2011-09-07 | 2020-05-13 | 프로린크스 엘엘시 | 생분해성 교차결합을 가지는 하이드로젤 |
| EP3242689A1 (en) * | 2015-01-09 | 2017-11-15 | Ascendis Pharma Growth Disorders A/S | Cnp prodrugs |
| PL3386531T3 (pl) * | 2015-12-08 | 2022-02-28 | Biomarin Pharmaceutical Inc. | Zastosowanie wariantów peptydu natriuretycznego typu c w leczeniu choroby zwyrodnieniowej stawów |
| IL259827B2 (en) * | 2016-01-08 | 2025-07-01 | Ascendis Pharma Growth Disorders As | Controlled-release CNP agonists with low initial NPR-B activity |
| LT3400019T (lt) * | 2016-01-08 | 2022-12-12 | Ascendis Pharma Growth Disorders A/S | Cnp provaistai su prie žiedo fragmento prijungtu nešikliu |
| NZ743487A (en) * | 2016-01-08 | 2023-02-24 | Ascendis Pharma Growth Disorders As | Controlled-release cnp agonists with increased nep stability |
| EP3922269A1 (en) * | 2016-03-16 | 2021-12-15 | Prolynx LLC | Extended release conjugates of exenatide analogs |
| US11896671B2 (en) * | 2016-07-13 | 2024-02-13 | Ascendis Pharma A/S | Conjugation method for carrier-linked prodrugs |
| WO2020206358A1 (en) * | 2019-04-05 | 2020-10-08 | Prolynx Llc | Improved conjugation linkers |
| KR20220004134A (ko) * | 2019-04-26 | 2022-01-11 | 프로린크스 엘엘시 | 서방형 사이토카인 컨쥬게이트 |
-
2021
- 2021-11-24 WO PCT/US2021/060763 patent/WO2022115563A1/en not_active Ceased
- 2021-11-24 CN CN202180079063.9A patent/CN116635027A/zh active Pending
- 2021-11-24 EP EP21899093.5A patent/EP4251150A4/en active Pending
- 2021-11-24 US US18/038,687 patent/US20240041982A1/en active Pending
- 2021-11-24 JP JP2023531536A patent/JP7837333B2/ja active Active
-
2025
- 2025-09-12 JP JP2025151940A patent/JP2025176137A/ja active Pending
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