HUE057083T2 - C-típusú nátriuretikus peptid változatainak alkalmazása oszteoartritisz kezelésére - Google Patents

C-típusú nátriuretikus peptid változatainak alkalmazása oszteoartritisz kezelésére

Info

Publication number
HUE057083T2
HUE057083T2 HUE16852866A HUE16852866A HUE057083T2 HU E057083 T2 HUE057083 T2 HU E057083T2 HU E16852866 A HUE16852866 A HU E16852866A HU E16852866 A HUE16852866 A HU E16852866A HU E057083 T2 HUE057083 T2 HU E057083T2
Authority
HU
Hungary
Prior art keywords
natriuretic peptide
type natriuretic
peptide variants
treat osteoarthritis
osteoarthritis
Prior art date
Application number
HUE16852866A
Other languages
English (en)
Inventor
Charles O'neill
Todd Oppeneer
Jason Pinkstaff
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of HUE057083T2 publication Critical patent/HUE057083T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2242Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/58Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HUE16852866A 2015-12-08 2016-12-08 C-típusú nátriuretikus peptid változatainak alkalmazása oszteoartritisz kezelésére HUE057083T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562264682P 2015-12-08 2015-12-08

Publications (1)

Publication Number Publication Date
HUE057083T2 true HUE057083T2 (hu) 2022-04-28

Family

ID=59013378

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16852866A HUE057083T2 (hu) 2015-12-08 2016-12-08 C-típusú nátriuretikus peptid változatainak alkalmazása oszteoartritisz kezelésére

Country Status (17)

Country Link
US (2) US11202819B2 (hu)
EP (2) EP3386531B1 (hu)
JP (1) JP7104625B2 (hu)
KR (1) KR20180088459A (hu)
CN (1) CN108697766A (hu)
AU (2) AU2016365751B2 (hu)
CA (1) CA3007315A1 (hu)
DK (1) DK3386531T3 (hu)
ES (1) ES2901769T3 (hu)
HR (1) HRP20211908T1 (hu)
HU (1) HUE057083T2 (hu)
IL (1) IL259690B2 (hu)
MX (1) MX2018006986A (hu)
PL (1) PL3386531T3 (hu)
PT (1) PT3386531T (hu)
RU (2) RU2759679C2 (hu)
WO (1) WO2017100400A2 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3400022A1 (en) 2016-01-08 2018-11-14 Ascendis Pharma Growth Disorders A/S Controlled-release cnp agonists with low initial npr-b activity
BR112018011008A2 (pt) 2016-01-08 2018-12-04 Ascendis Pharma Growth Disorders As agonistas de cnp de liberação controlada com ligação a npr-c baixa
AU2017205273C1 (en) 2016-01-08 2022-12-01 Ascendis Pharma Growth Disorders A/S Controlled-release CNP agonists with reduced side-effects
WO2017118700A1 (en) 2016-01-08 2017-07-13 Ascendis Pharma Growth Disorders A/S Controlled-release cnp agonists with increased nep stability
EP3400019B1 (en) 2016-01-08 2022-09-28 Ascendis Pharma Growth Disorders A/S Cnp prodrugs with carrier attachment at the ring moiety
WO2017118693A1 (en) 2016-01-08 2017-07-13 Ascendis Pharma Growth Disorders A/S Cnp prodrugs with large carrier moieties
KR102531327B1 (ko) 2016-09-29 2023-05-11 아센디스 파마 그로우쓰 디스오더스 에이/에스 조절 방출 cnp 아고니스트를 사용한 병용 요법
BR112020021966A2 (pt) * 2018-04-27 2021-01-26 Remy Biosciences, Inc. dispositivos médicos, veículos de liberação e fabricação dos mesmos
JP2022520193A (ja) * 2019-02-11 2022-03-29 アセンディス ファーマ グロース ディスオーダーズ エー/エス Cnpコンジュゲートの乾燥医薬製剤
EP4337957A1 (en) * 2021-05-11 2024-03-20 Texas Tech University System Targeted selenium conjugates as countermeasures for pathogenic viruses and cells
WO2023108005A1 (en) * 2021-12-07 2023-06-15 Biomarin Pharmaceutical Inc. C-type natriuretic peptide therapy of bone-related disorders
WO2024104922A1 (en) 2022-11-14 2024-05-23 Ascendis Pharma Growth Disorders A/S Method of improving skeletal muscle function

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252714A (en) 1990-11-28 1993-10-12 The University Of Alabama In Huntsville Preparation and use of polyethylene glycol propionaldehyde
JP2809533B2 (ja) 1991-01-31 1998-10-08 壽之 松尾 Cnp類似体ペプチド
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
IL142118A0 (en) 2001-03-20 2002-03-10 Prochon Biotech Ltd Method and composition for treatment of skeletal dysplasias
WO2005094890A1 (ja) * 2004-03-31 2005-10-13 Kazuwa Nakao 身長増加用組成物
WO2005094889A1 (ja) 2004-03-31 2005-10-13 Chugai Seiyaku Kabushiki Kaisha 関節炎症治療剤又は予防剤
CL2008003476A1 (es) 2007-11-21 2009-08-14 Biomarin Pharm Inc Variante del peptido natriuretico de tipo c (cnp); composicion farmaceutica que la comprende; y su uso para tratar una displasia del esqueleto o un trastorno de la musculatura lisa vascular.
ES2904360T3 (es) 2009-05-20 2022-04-04 Biomarin Pharm Inc Variantes de péptido natriurético de tipo C
EP2658979B1 (en) * 2010-12-27 2018-02-14 Alexion Pharmaceuticals, Inc. Compositions comprising natriuretic peptides and methods of use thereof

Also Published As

Publication number Publication date
DK3386531T3 (da) 2022-01-03
RU2759679C2 (ru) 2021-11-16
EP3386531B1 (en) 2021-10-13
JP2019505486A (ja) 2019-02-28
RU2021132347A (ru) 2022-03-24
WO2017100400A2 (en) 2017-06-15
ES2901769T3 (es) 2022-03-23
EP4019038A3 (en) 2022-09-28
HRP20211908T1 (hr) 2022-03-04
JP7104625B2 (ja) 2022-07-21
US20220160836A1 (en) 2022-05-26
PL3386531T3 (pl) 2022-02-28
MX2018006986A (es) 2018-09-05
CN108697766A (zh) 2018-10-23
PT3386531T (pt) 2021-12-29
IL259690B (en) 2022-10-01
AU2016365751B2 (en) 2023-12-21
AU2016365751A1 (en) 2018-06-21
RU2018124600A3 (hu) 2020-01-13
EP4019038A2 (en) 2022-06-29
IL259690B2 (en) 2023-02-01
US20190247467A1 (en) 2019-08-15
RU2018124600A (ru) 2020-01-13
EP3386531A2 (en) 2018-10-17
US11202819B2 (en) 2021-12-21
WO2017100400A3 (en) 2017-10-26
AU2024201852A1 (en) 2024-04-11
IL259690A (en) 2018-07-31
KR20180088459A (ko) 2018-08-03
CA3007315A1 (en) 2017-06-15

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