JP2023511184A5 - - Google Patents
Info
- Publication number
- JP2023511184A5 JP2023511184A5 JP2022544413A JP2022544413A JP2023511184A5 JP 2023511184 A5 JP2023511184 A5 JP 2023511184A5 JP 2022544413 A JP2022544413 A JP 2022544413A JP 2022544413 A JP2022544413 A JP 2022544413A JP 2023511184 A5 JP2023511184 A5 JP 2023511184A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- val
- cit
- gly
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062964181P | 2020-01-22 | 2020-01-22 | |
| US62/964,181 | 2020-01-22 | ||
| PCT/EP2021/051259 WO2021148500A1 (en) | 2020-01-22 | 2021-01-21 | Compounds and conjugates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023511184A JP2023511184A (ja) | 2023-03-16 |
| JP2023511184A5 true JP2023511184A5 (https=) | 2024-01-30 |
Family
ID=74494865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022544413A Pending JP2023511184A (ja) | 2020-01-22 | 2021-01-21 | 化合物及びその複合体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230097908A1 (https=) |
| EP (1) | EP4093439A1 (https=) |
| JP (1) | JP2023511184A (https=) |
| KR (1) | KR20220130749A (https=) |
| CN (1) | CN114980934A (https=) |
| AU (1) | AU2021210570A1 (https=) |
| BR (1) | BR112022014391A2 (https=) |
| CA (1) | CA3166732A1 (https=) |
| MX (1) | MX2022009052A (https=) |
| WO (1) | WO2021148500A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3241157A1 (en) * | 2021-12-16 | 2023-06-22 | Wei Zhou | Camptothecin compound and conjugate thereof |
| AU2023279443A1 (en) | 2022-06-03 | 2025-01-23 | Ube Corporation | Antibody-multidrug conjugate |
| CN115160403B (zh) * | 2022-07-05 | 2025-06-27 | 博石丰生命科技(南通)有限公司 | 特异性拓扑异构酶抑制剂和可用于抗体药物偶联物及其制备方法 |
| WO2026078165A1 (en) | 2024-10-10 | 2026-04-16 | Astrazeneca Ab | Conjugates comprising cleavable linkers |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4939255A (en) * | 1987-06-24 | 1990-07-03 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic camptothecin derivatives |
| JP2540357B2 (ja) * | 1987-06-24 | 1996-10-02 | 第一製薬株式会社 | 六環性化合物 |
| JP3008226B2 (ja) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | 六環性化合物 |
| DK1791565T3 (en) | 2004-09-23 | 2016-08-01 | Genentech Inc | Cysteingensplejsede antibodies and conjugates |
| SI1934174T1 (sl) | 2005-10-07 | 2011-08-31 | Exelixis Inc | Inhibitorji MEK in postopki za njihovo uporabo |
| RS52060B (sr) | 2006-01-25 | 2012-04-30 | Sanofi | Citotoksični agensi koji sadrže nove derivate tomaimicina |
| JP5394246B2 (ja) * | 2007-03-30 | 2014-01-22 | ジェネンテック， インコーポレイテッド | 抗体及びイムノコンジュゲートとこれらの使用方法 |
| CL2008001334A1 (es) | 2007-05-08 | 2008-09-22 | Genentech Inc | Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer. |
| NZ584514A (en) | 2007-10-19 | 2012-07-27 | Genentech Inc | Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates |
| AU2010295646B2 (en) * | 2009-09-15 | 2016-02-11 | Ellipses Pharma Limited | Treatment of cancer |
| KR102445502B1 (ko) * | 2014-04-10 | 2022-09-21 | 다이이찌 산쿄 가부시키가이샤 | 항her3 항체-약물 콘주게이트 |
| AU2016359230B2 (en) * | 2015-11-25 | 2020-04-23 | Ligachem Biosciences Inc. | Conjugates comprising self-immolative groups and methods related thereto |
| GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| AU2017359155A1 (en) | 2016-11-10 | 2019-06-13 | Medimmune, Llc | Binding molecules specific for ASCT2 and uses thereof |
| JP7244987B2 (ja) * | 2016-12-14 | 2023-03-23 | シージェン インコーポレイテッド | 多剤抗体薬物コンジュゲート |
| WO2019195535A1 (en) * | 2018-04-05 | 2019-10-10 | Novartis Ag | Trispecific binding molecules against cancers and uses thereof |
| SG11202010496WA (en) * | 2018-05-18 | 2020-12-30 | Daiichi Sankyo Co Ltd | Anti-muc1 antibody-drug conjugate |
| MX2021011812A (es) * | 2019-03-29 | 2021-10-22 | Medimmune Ltd | Compuestos y conjugados de estos. |
| CN110974975B (zh) * | 2019-12-12 | 2023-10-20 | 成都百利多特生物药业有限责任公司 | 一种快速释放的抗体药物偶联物 |
| CN116390771A (zh) * | 2020-07-13 | 2023-07-04 | 瑞泽恩制药公司 | 与蛋白中的谷氨酰胺残基缀合的喜树碱类似物及其用途 |
| NL2026947B1 (en) * | 2020-11-20 | 2022-07-01 | Synaffix Bv | Tyrosine-based antibody conjugates |
-
2021
- 2021-01-21 EP EP21702596.4A patent/EP4093439A1/en not_active Withdrawn
- 2021-01-21 CA CA3166732A patent/CA3166732A1/en active Pending
- 2021-01-21 KR KR1020227028552A patent/KR20220130749A/ko active Pending
- 2021-01-21 US US17/759,083 patent/US20230097908A1/en not_active Abandoned
- 2021-01-21 MX MX2022009052A patent/MX2022009052A/es unknown
- 2021-01-21 JP JP2022544413A patent/JP2023511184A/ja active Pending
- 2021-01-21 WO PCT/EP2021/051259 patent/WO2021148500A1/en not_active Ceased
- 2021-01-21 AU AU2021210570A patent/AU2021210570A1/en not_active Abandoned
- 2021-01-21 CN CN202180010092.XA patent/CN114980934A/zh active Pending
- 2021-01-21 BR BR112022014391A patent/BR112022014391A2/pt not_active IP Right Cessation
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