JP2023512501A5 - - Google Patents

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Publication number
JP2023512501A5
JP2023512501A5 JP2022544188A JP2022544188A JP2023512501A5 JP 2023512501 A5 JP2023512501 A5 JP 2023512501A5 JP 2022544188 A JP2022544188 A JP 2022544188A JP 2022544188 A JP2022544188 A JP 2022544188A JP 2023512501 A5 JP2023512501 A5 JP 2023512501A5
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JP
Japan
Application number
JP2022544188A
Other languages
Japanese (ja)
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JP2023512501A (ja
JPWO2021148501A5 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/051263 external-priority patent/WO2021148501A1/en
Publication of JP2023512501A publication Critical patent/JP2023512501A/ja
Publication of JPWO2021148501A5 publication Critical patent/JPWO2021148501A5/ja
Publication of JP2023512501A5 publication Critical patent/JP2023512501A5/ja
Withdrawn legal-status Critical Current

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JP2022544188A 2020-01-22 2021-01-21 化合物及びその複合体 Withdrawn JP2023512501A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062964180P 2020-01-22 2020-01-22
US62/964,180 2020-01-22
US202063085414P 2020-09-30 2020-09-30
US63/085,414 2020-09-30
PCT/EP2021/051263 WO2021148501A1 (en) 2020-01-22 2021-01-21 Compounds and conjugates thereof

Publications (3)

Publication Number Publication Date
JP2023512501A JP2023512501A (ja) 2023-03-27
JPWO2021148501A5 JPWO2021148501A5 (https=) 2024-01-19
JP2023512501A5 true JP2023512501A5 (https=) 2024-01-19

Family

ID=74418415

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022544188A Withdrawn JP2023512501A (ja) 2020-01-22 2021-01-21 化合物及びその複合体

Country Status (15)

Country Link
US (1) US20230111996A1 (https=)
EP (1) EP4093438A1 (https=)
JP (1) JP2023512501A (https=)
KR (1) KR20220130191A (https=)
CN (1) CN115052633A (https=)
AU (1) AU2021211892A1 (https=)
BR (1) BR112022013966A2 (https=)
CA (1) CA3167373A1 (https=)
CO (1) CO2022011178A2 (https=)
CR (1) CR20220393A (https=)
EC (1) ECSP22064855A (https=)
IL (1) IL294645A (https=)
MX (1) MX2022008997A (https=)
TW (1) TW202140076A (https=)
WO (1) WO2021148501A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118414339A (zh) 2021-12-16 2024-07-30 迈威(上海)生物科技股份有限公司 一种喜树碱类化合物及其偶联物
CN115160403B (zh) * 2022-07-05 2025-06-27 博石丰生命科技(南通)有限公司 特异性拓扑异构酶抑制剂和可用于抗体药物偶联物及其制备方法
JP2025524728A (ja) 2022-07-15 2025-07-30 フィアン セラピューティクス エルティーディー 抗体-薬物複合体
EP4309676A1 (en) * 2022-07-22 2024-01-24 Emergence Therapeutics AG Novel anti-nectin-4 antibody camptothecin derivative conjugates
EP4583921A1 (en) * 2022-09-07 2025-07-16 Xadcera Biopharmaceutical (Suzhou) Co., Ltd. Anti-trop2/egfr antibodies and uses thereof
CN119630672B (zh) * 2023-02-23 2026-01-30 一线医药(杭州)有限公司 喜树碱衍生物及其偶联物以及其制备方法和医药用途
TW202508638A (zh) * 2023-05-12 2025-03-01 大陸商百奧賽圖(北京)醫藥科技股份有限公司 連結子化合物及配體-藥物接合物、其製備方法及用途
EP4721767A1 (en) 2023-06-05 2026-04-08 Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. Anti-b7-h3 antibody or fragment thereof, and antibody drug conjugate targeting b7-h3
WO2025103192A1 (zh) * 2023-11-16 2025-05-22 上海齐鲁制药研究中心有限公司 一种氘代喜树碱化合物及其制备和应用
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4939255A (en) * 1987-06-24 1990-07-03 Daiichi Pharmaceutical Co., Ltd. Hexa-cyclic camptothecin derivatives
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
KR101270829B1 (ko) 2004-09-23 2013-06-07 제넨테크, 인크. 시스테인 유전자조작 항체 및 접합체
HRP20110498T1 (hr) 2005-10-07 2011-08-31 Exelixis Azetidini kao inhibitori mek za liječenje proliferativnih bolesti
SI1813614T1 (sl) 2006-01-25 2012-01-31 Sanofi 174 Citotoksična sredstva, ki obsegajo nove tomajmicinske derivate
EP2144628B1 (en) 2007-05-08 2012-10-17 Genentech, Inc. Cysteine engineered anti-muc16 antibodies and antibody drug conjugates
MX2010003718A (es) 2007-10-19 2010-04-21 Genentech Inc Anticuerpos anti-tenb2 producidos por ingenieria de cisteina y conjugados de farmaco y anticuerpo.
GB201506393D0 (en) * 2015-04-15 2015-05-27 Berkel Patricius H C Van And Howard Philip W Site-specific antibody-drug conjugates
EP3362100B1 (en) * 2015-10-16 2022-06-22 Genentech, Inc. Hindered disulfide drug conjugates
GB201607478D0 (en) 2016-04-29 2016-06-15 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
WO2018089393A1 (en) 2016-11-10 2018-05-17 Medimmune, Llc Binding molecules specific for asct2 and uses thereof
HUE060364T2 (hu) * 2019-03-29 2023-02-28 Medimmune Ltd Vegyületek és konjugátumaik
CR20230146A (es) * 2020-09-11 2023-06-07 Medimmune Ltd Moléculas de unión a b7-h4 terapéuticas

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