JP2019500058A - α−アミラーゼ組み合わせ変異体 - Google Patents

α−アミラーゼ組み合わせ変異体 Download PDF

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Publication number
JP2019500058A
JP2019500058A JP2018549408A JP2018549408A JP2019500058A JP 2019500058 A JP2019500058 A JP 2019500058A JP 2018549408 A JP2018549408 A JP 2018549408A JP 2018549408 A JP2018549408 A JP 2018549408A JP 2019500058 A JP2019500058 A JP 2019500058A
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Prior art keywords
amylase
mutant
starch
amino acid
enzyme
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JP2019500058A5 (https=
Inventor
ケヴァス、ウィリアム
シャーマ、ヴィヴェック
ワイルズ、デイビッド・イー
リー、サン‐キュ
フィナン・ディナ
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ダニスコ・ユーエス・インク
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Publication of JP2019500058A publication Critical patent/JP2019500058A/ja
Publication of JP2019500058A5 publication Critical patent/JP2019500058A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
JP2018549408A 2015-12-09 2016-12-09 α−アミラーゼ組み合わせ変異体 Pending JP2019500058A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562265301P 2015-12-09 2015-12-09
US62/265,301 2015-12-09
PCT/US2016/066031 WO2017100720A1 (en) 2015-12-09 2016-12-09 Alpha-amylase combinatorial variants

Publications (2)

Publication Number Publication Date
JP2019500058A true JP2019500058A (ja) 2019-01-10
JP2019500058A5 JP2019500058A5 (https=) 2019-10-17

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018549408A Pending JP2019500058A (ja) 2015-12-09 2016-12-09 α−アミラーゼ組み合わせ変異体

Country Status (6)

Country Link
US (4) US11920170B2 (https=)
EP (2) EP3387124B1 (https=)
JP (1) JP2019500058A (https=)
CN (1) CN108779448B (https=)
DK (1) DK3387124T3 (https=)
WO (1) WO2017100720A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022041064A (ja) * 2020-08-31 2022-03-11 花王株式会社 α－アミラーゼ変異体
JP2023095355A (ja) * 2021-12-24 2023-07-06 花王株式会社 アミラーゼ配合洗浄剤組成物

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11920170B2 (en) * 2015-12-09 2024-03-05 Danisco Us Inc. Alpha-amylase combinatorial variants
WO2019040412A1 (en) 2017-08-23 2019-02-28 Danisco Us Inc METHODS AND COMPOSITIONS FOR EFFICIENT GENETIC MODIFICATION OF BACILLUS LICHENIFORMIS STRAINS
BR112020022475A2 (pt) * 2018-05-04 2021-02-09 Danisco Us Inc. processo simplificado para produzir maltodextrina e xaropes de especialidade
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
EP3830231A1 (en) * 2018-07-31 2021-06-09 Danisco US Inc. Variant alpha-amylases having amino acid substitutions that lower the pka of the general acid
BR112021006967A2 (pt) * 2018-10-12 2021-07-13 Danisco Us Inc. alfa-amilases com mutações que melhoram a estabilidade na presença de quelantes
CN113302270A (zh) * 2018-12-03 2021-08-24 诺维信公司 低pH粉末洗涤剂组合物
WO2020260223A1 (en) * 2019-06-24 2020-12-30 Novozymes A/S Alpha-amylase variants
EP4031560A1 (en) 2019-08-14 2022-07-27 Danisco US Inc Compositions and methods for increased protein production in bacillus licheniformis
BR112022007697A2 (pt) * 2019-10-24 2022-07-12 Danisco Us Inc Alfa-amilase variante que forma maltopentaose/maltohexaose
AU2020405786A1 (en) * 2019-12-20 2022-08-11 Henkel Ag & Co. Kgaa Cleaning compositions comprising dispersins IX
US20230167386A1 (en) * 2020-05-21 2023-06-01 Dupont Nutrition Biosciences Aps Uninhibited amylases for brewing with high tannin materials
EP4223879A4 (en) * 2020-10-02 2024-12-11 Kao Corporation Alpha-amylase variant
EP4387982A2 (en) * 2021-08-20 2024-06-26 Danisco US Inc. Methods and compositions for enhanced protein production in bacillus cells
EP4433586A2 (en) * 2021-11-18 2024-09-25 Danisco US Inc. High performance alpha-amylases for starch liquefaction
EP4525615A2 (en) 2022-05-14 2025-03-26 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014164834A1 (en) * 2013-03-11 2014-10-09 Danisco Us Inc. Alpha-amylase combinatorial variants

Family Cites Families (192)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
GB1483591A (en) 1973-07-23 1977-08-24 Novo Industri As Process for coating water soluble or water dispersible particles by means of the fluid bed technique
GB1590432A (en) 1976-07-07 1981-06-03 Novo Industri As Process for the production of an enzyme granulate and the enzyme granuate thus produced
JPS5534046A (en) 1978-09-01 1980-03-10 Cpc International Inc Novel glucoamyrase having excellent heat resistance and production
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
NO840200L (no) 1983-01-28 1984-07-30 Cefus Corp Glukoamylase cdna.
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US4536477A (en) 1983-08-17 1985-08-20 Cpc International Inc. Thermostable glucoamylase and method for its production
US5422267A (en) 1984-05-22 1995-06-06 Robert R. Yocum Industrial yeast comprising an integrated glucoamylase gene
US5763257A (en) 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
DK263584D0 (da) 1984-05-29 1984-05-29 Novo Industri As Enzymholdige granulater anvendt som detergentadditiver
US5972682A (en) 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US4587215A (en) 1984-06-25 1986-05-06 Uop Inc. Highly thermostable amyloglucosidase
US4628031A (en) 1984-09-18 1986-12-09 Michigan Biotechnology Institute Thermostable starch converting enzymes
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
EG18543A (en) 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
DE3750450T2 (de) 1986-08-29 1995-01-05 Novo Industri As Enzymhaltiger Reinigungsmittelzusatz.
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
EP0305216B1 (en) 1987-08-28 1995-08-02 Novo Nordisk A/S Recombinant Humicola lipase and process for the production of recombinant humicola lipases
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
DE68924654T2 (de) 1988-01-07 1996-04-04 Novonordisk As Spezifische Protease.
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体ｄｎａ、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
JP2728531B2 (ja) 1988-03-24 1998-03-18 ノボ ノルディスク アクティーゼルスカブ セルラーゼ調製品
US5648263A (en) 1988-03-24 1997-07-15 Novo Nordisk A/S Methods for reducing the harshness of a cotton-containing fabric
WO1991000353A2 (en) 1989-06-29 1991-01-10 Gist-Brocades N.V. MUTANT MICROBIAL α-AMYLASES WITH INCREASED THERMAL, ACID AND/OR ALKALINE STABILITY
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
KR100236540B1 (ko) 1990-04-14 2000-01-15 레클로우크스 라우에르 알카리성 바실러스-리파제, 이를 코-딩하는 dna 서열 및 리파제를 생산하는 바실러스 균주
DK0531372T4 (da) 1990-05-09 2004-08-09 Novozymes As Cellulasepræparat omfattende et endoglucanaseenzym
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
US5162210A (en) 1990-06-29 1992-11-10 Iowa State University Research Foundation Process for enzymatic hydrolysis of starch to glucose
AU657278B2 (en) 1990-09-13 1995-03-09 Novo Nordisk A/S Lipase variants
CZ37393A3 (en) 1990-09-28 1994-04-13 Procter & Gamble Liquid cleansing preparation with enhanced stability and cleansing efficiency of enzyme
ES2174820T3 (es) 1991-01-16 2002-11-16 Procter & Gamble Composiciones detergentes compactas con celulasa de alta actividad.
CZ285148B6 (cs) 1991-04-30 1999-05-12 The Procter And Gamble Company Kapalné detergentní směsi s borito-polyolovým komplexem k inhibici proteolytického enzymu
EP0511456A1 (en) 1991-04-30 1992-11-04 The Procter & Gamble Company Liquid detergents with aromatic borate ester to inhibit proteolytic enzyme
ES2121014T3 (es) 1991-05-01 1998-11-16 Novo Nordisk As Enzimas estabilizadas y composiciones detergentes.
US5340735A (en) 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
DK72992D0 (da) 1992-06-01 1992-06-01 Novo Nordisk As Enzym
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
WO1994002597A1 (en) 1992-07-23 1994-02-03 Novo Nordisk A/S MUTANT α-AMYLASE, DETERGENT, DISH WASHING AGENT, AND LIQUEFACTION AGENT
ATE262035T1 (de) 1992-10-06 2004-04-15 Novozymes As Zellulosevarianten
US5281526A (en) 1992-10-20 1994-01-25 Solvay Enzymes, Inc. Method of purification of amylase by precipitation with a metal halide and 4-hydroxybenzic acid or a derivative thereof
KR950702240A (ko) 1993-04-27 1995-06-19 한스 발터 라벤 세제로의 이용을 위한 새로운 리파제 변형체
DK52393D0 (https=) 1993-05-05 1993-05-05 Novo Nordisk As
DK76893D0 (https=) 1993-06-28 1993-06-28 Novo Nordisk As
US5335791A (en) 1993-08-12 1994-08-09 Simco/Ramic Corporation Backlight sorting system and method
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
CA2173329C (en) 1993-10-08 2011-07-12 Henrik Bisgard-Frantzen Amylase variants
US5817495A (en) 1993-10-13 1998-10-06 Novo Nordisk A/S H2 O2 -stable peroxidase variants
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
DE69527835T2 (de) 1994-02-22 2003-04-10 Novozymes A/S, Bagsvaerd Methode zur herstellung einer variante eines lipolytischen enzymes
EP1921147B1 (en) 1994-02-24 2011-06-08 Henkel AG & Co. KGaA Improved enzymes and detergents containing them
ES2364774T3 (es) 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
US5691295A (en) 1995-01-17 1997-11-25 Cognis Gesellschaft Fuer Biotechnologie Mbh Detergent compositions
DE69536145D1 (de) 1994-03-08 2011-04-07 Novozymes As Neuartige alkalische Zellulasen
US5824531A (en) 1994-03-29 1998-10-20 Novid Nordisk Alkaline bacilus amylase
WO1995030744A2 (en) 1994-05-04 1995-11-16 Genencor International Inc. Lipases with improved surfactant resistance
DE69534685T2 (de) * 1994-06-15 2006-09-07 Kirin Beer K.K. Transferase und amylase, verfahren zur herstellung dieser enzyme, ihre verwendung und für die kodierende gene
JP4335272B2 (ja) * 1994-06-15 2009-09-30 キリンホールディングス株式会社 新規トランスフェラーゼ及びアミラーゼ、それらの製造法及び利用、並びに該新規酵素類の遺伝子
DK0772684T3 (da) 1994-06-17 2005-12-12 Genencor Int Amylolytiske enzymer afledt fra B. Licheniformis alpha-amylasen med forbedrede karakteristika
WO1995035381A1 (en) 1994-06-20 1995-12-28 Unilever N.V. Modified pseudomonas lipases and their use
AU2884695A (en) 1994-06-23 1996-01-19 Unilever Plc Modified pseudomonas lipases and their use
PL318209A1 (en) 1994-08-11 1997-05-26 Genencor Int Improved cleaning composition
DE69535733T2 (de) 1994-10-06 2009-04-23 Novozymes A/S Ein enzympräparat mit endoglucanase aktivität
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
US5827719A (en) 1994-10-26 1998-10-27 Novo Nordisk A/S Enzyme with lipolytic activity
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
KR100511499B1 (ko) 1995-02-03 2005-12-21 노보자임스 에이/에스 소정 특성을 가지는 알파-아밀라제 돌연변이체를 디자인하는 방법
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
CN102080070B (zh) 1995-03-17 2016-01-20 诺沃奇梅兹有限公司 新的内切葡聚糖酶
EP0815193A1 (en) 1995-03-24 1998-01-07 Genencor International Inc. An improved laundry detergent composition comprising amylase
EP0839186B1 (en) 1995-07-14 2004-11-10 Novozymes A/S A modified enzyme with lipolytic activity
EP0839224A1 (en) 1995-07-19 1998-05-06 Novo Nordisk A/S Treatment of fabrics
AU6655196A (en) 1995-08-11 1997-03-12 Novo Nordisk A/S Novel lipolytic enzymes
WO1997010342A1 (en) 1995-09-13 1997-03-20 Genencor International, Inc. Alkaliphilic and thermophilic microorganisms and enzymes obtained therefrom
ES2432519T3 (es) 1996-04-30 2013-12-04 Novozymes A/S Mutantes de alfa-amilasa
US6211134B1 (en) 1996-05-14 2001-04-03 Genecor International, Inc. Mutant α-amylase
US5763385A (en) 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
AU3938997A (en) 1996-08-26 1998-03-19 Novo Nordisk A/S A novel endoglucanase
EP1726644A1 (en) 1996-09-17 2006-11-29 Novozymes A/S Cellulase variants
WO1998015257A1 (en) 1996-10-08 1998-04-16 Novo Nordisk A/S Diaminobenzoic acid derivatives as dye precursors
JP4044143B2 (ja) 1996-11-04 2008-02-06 ノボザイムス アクティーゼルスカブ ズブチラーゼ変異体及び組成物
EP0932667B1 (en) 1996-11-04 2008-10-01 Novozymes A/S Subtilase variants and compositions
CA2274806C (en) 1996-12-09 2011-02-01 Genencor International, Inc. H mutant alpha-amylase enzymes
WO1998034946A1 (en) 1997-02-12 1998-08-13 Massachusetts Institute Of Technology Daxx, a novel fas-binding protein that activates jnk and apoptosis
JPH10262661A (ja) * 1997-03-25 1998-10-06 Cci Corp 新規なα−アミラーゼおよびその単離方法
EP1002061A1 (en) 1997-07-04 2000-05-24 Novo Nordisk A/S FAMILY 6 ENDO-1,4-$g(b)-GLUCANASE VARIANTS AND CLEANING COMPOSIT IONS CONTAINING THEM
US6008026A (en) 1997-07-11 1999-12-28 Genencor International, Inc. Mutant α-amylase having introduced therein a disulfide bond
US6080568A (en) 1997-08-19 2000-06-27 Genencor International, Inc. Mutant α-amylase comprising modification at residues corresponding to A210, H405 and/or T412 in Bacillus licheniformis
US6187576B1 (en) 1997-10-13 2001-02-13 Novo Nordisk A/S α-amylase mutants
AR015977A1 (es) 1997-10-23 2001-05-30 Genencor Int Variantes de proteasa multiplemente substituida con carga neta alterada para su empleo en detergentes
US6204232B1 (en) 1997-10-30 2001-03-20 Novo Nordisk A/S α-amlase mutants
CN1261567C (zh) 1997-11-26 2006-06-28 诺维信公司 热稳定的葡糖淀粉酶
DE69837559T3 (de) 1997-12-24 2011-07-21 Genencor International, Inc., Calif. Verfahren zur Bestimmung der Waschleistung eines Enzyms.
AU2411699A (en) 1998-02-18 1999-09-06 Novo Nordisk A/S Alkaline bacillus amylase
WO1999043793A1 (en) 1998-02-27 1999-09-02 Novo Nordisk A/S Amylolytic enzyme variants
CN1292028B (zh) 1998-02-27 2013-08-14 诺维信公司 麦芽α淀粉酶变体
KR20010041617A (ko) 1998-03-09 2001-05-25 피아 스타르 전분으로부터 글루코스 시럽의 효소성 제조
MXPA01000352A (es) 1998-07-15 2002-06-04 Novozymes As Varientes de glucoamilasa.
DE19834180A1 (de) 1998-07-29 2000-02-03 Benckiser Nv Zusammensetzung zur Verwendung in einer Geschirrspülmaschine
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
US6197565B1 (en) 1998-11-16 2001-03-06 Novo-Nordisk A/S α-Amylase variants
WO2000060059A2 (en) 1999-03-30 2000-10-12 NovozymesA/S Alpha-amylase variants
ATE422538T1 (de) 1999-03-31 2009-02-15 Novozymes As Polypeptide mit alkaliner alpha-amylase-aktivität und für diese kodierende nukleinsäuren
JP4745503B2 (ja) 1999-03-31 2011-08-10 ノボザイムス アクティーゼルスカブ アルカリα−アミラーゼ活性を有するポリペプチド及びそれらをコードする核酸
JP4741128B2 (ja) 1999-08-20 2011-08-03 ノボザイムス アクティーゼルスカブ アルカリバチルスアミラーゼ
US6254645B1 (en) 1999-08-20 2001-07-03 Genencor International, Inc. Enzymatic modification of the surface of a polyester fiber or article
US6933140B1 (en) 1999-11-05 2005-08-23 Genencor International, Inc. Enzymes useful for changing the properties of polyester
AU1269601A (en) 1999-11-10 2001-06-06 Novozymes A/S Fungamyl-like alpha-amylase variants
AU3724801A (en) 2000-03-03 2001-09-12 Novozymes A/S Polypeptides having alkaline alpha-amylase activity and nucleic acids encoding same
JP5571274B2 (ja) 2000-03-08 2014-08-13 ノボザイムス アクティーゼルスカブ 改変された特性を有する変異体
US20030104969A1 (en) 2000-05-11 2003-06-05 Caswell Debra Sue Laundry system having unitized dosing
AU2001258229A1 (en) 2000-05-12 2001-11-26 Novozymes A/S Alpha-amylase variants with altered 1,6-activity
WO2001096537A2 (en) 2000-06-14 2001-12-20 Novozymes A/S Pre-oxidized alpha-amylase
EP2308980A3 (en) 2000-08-01 2011-04-27 Novozymes A/S Alpha-amylase mutants with altered properties
EP1326965A2 (en) 2000-10-13 2003-07-16 Novozymes A/S Alpha-amylase variant with altered properties
ES2431044T5 (es) 2000-11-27 2022-05-27 Procter & Gamble Método de lavado de vajillas
CA2426645C (en) 2000-11-27 2008-06-10 The Procter & Gamble Company Detergent pouch comprising superposed or superposable compartments
ATE449840T1 (de) 2001-05-15 2009-12-15 Novozymes As Alpha-amylasevariante mit veränderten eigenschaften
DE10138753B4 (de) 2001-08-07 2017-07-20 Henkel Ag & Co. Kgaa Wasch- und Reinigungsmittel mit Hybrid-Alpha-Amylasen
EP1354939A1 (en) 2002-04-19 2003-10-22 The Procter & Gamble Company Pouched cleaning compositions
AU2004252572B2 (en) 2003-06-25 2011-09-08 Novozymes A/S Polypeptides having alpha-amylase activity and polypeptides encoding same
WO2005003311A2 (en) 2003-06-25 2005-01-13 Novozymes A/S Enzymes for starch processing
ES2383366T3 (es) 2003-06-25 2012-06-20 Novozymes A/S Enzimas para el tratamiento de almidón
EP1664285A2 (en) 2003-08-22 2006-06-07 Novozymes A/S Fungal alpha-amylase variants
WO2005018336A1 (en) 2003-08-22 2005-03-03 Novozymes A/S Process for preparing a dough comprising a starch-degrading glucogenic exo-amylase of family 13
EP1516917B1 (en) 2003-09-22 2006-07-26 The Procter & Gamble Company Liquid unit dose detergent composition
US8703459B2 (en) 2003-12-05 2014-04-22 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Catalytic domains of beta(1,4)-galactosyltransferase I having altered metal ion specificity
DK1709167T3 (da) 2004-01-08 2010-08-16 Novozymes As Amylase
DE102004020720A1 (de) 2004-04-28 2005-12-01 Henkel Kgaa Verfahren zur Herstellung von Wasch- oder Reinigungsmitteln
US7413887B2 (en) 2004-05-27 2008-08-19 Genecor International, Inc. Trichoderma reesei glucoamylase and homologs thereof
GB0416155D0 (en) 2004-07-20 2004-08-18 Unilever Plc Laundry product
EP1797179A1 (en) 2004-08-02 2007-06-20 Novozymes A/S Maltogenic alpha-amylase variants
WO2006012902A2 (en) 2004-08-02 2006-02-09 Novozymes A/S Creation of diversity in polypeptides
EP2258837A1 (en) 2004-09-10 2010-12-08 Novozymes North America, Inc. Methods for preventing, removing, reducing, or disrupting biofilm
GB0423986D0 (en) 2004-10-29 2004-12-01 Unilever Plc Method of preparing a laundry product
US7659101B2 (en) 2004-12-15 2010-02-09 Novozymes A/S Alkaline Bacillus amylase
CA2592083C (en) 2004-12-22 2017-02-21 Novozymes A/S Hybrid enzymes consisting of an endo-amylase first amino acid sequence and a carbohydrate-binding module as second amino acid sequence
AU2006261444A1 (en) 2005-06-24 2006-12-28 Novozymes A/S Amylases for pharmaceutical use
US20080293610A1 (en) 2005-10-12 2008-11-27 Andrew Shaw Use and production of storage-stable neutral metalloprotease
CA2642970C (en) 2006-03-22 2013-09-24 The Procter & Gamble Company Liquid treatment compositions comprising pearlescent agents
EP2038410A1 (en) 2006-06-30 2009-03-25 Novozymes A/S Bacterial alpha-amylase variants
GB0613069D0 (en) 2006-06-30 2006-08-09 Unilever Plc Laundry articles
KR20090031906A (ko) 2006-07-18 2009-03-30 다니스코 유에스 인크. 광범위한 온도에 걸쳐 활성인 프로테아제 변이형
BRPI0722093A2 (pt) 2006-12-21 2014-04-01 Danisco Us Inc Genencor Div Composições e usos para um polipeptídeo de alfa-amilase da espécie bacillus 195
GB0700931D0 (en) 2007-01-18 2007-02-28 Reckitt Benckiser Nv Dosage element and a method of manufacturing a dosage element
WO2008092919A1 (en) 2007-02-01 2008-08-07 Novozymes A/S Alpha-amylase and its use
US8021863B2 (en) 2007-02-19 2011-09-20 Novozymes A/S Polypeptides with starch debranching activity
US8206966B2 (en) 2007-11-05 2012-06-26 Danisco Us Inc. Alpha-amylase variants with altered properties
AU2009212526A1 (en) 2008-02-04 2009-08-13 Danisco Us Inc. TS23 alpha-amylase variants with altered properties
ES2465228T5 (es) 2008-02-08 2022-03-18 Procter & Gamble Proceso para fabricar una bolsa soluble en agua
US8066818B2 (en) 2008-02-08 2011-11-29 The Procter & Gamble Company Water-soluble pouch
US20090233830A1 (en) 2008-03-14 2009-09-17 Penny Sue Dirr Automatic detergent dishwashing composition
EP2107107A1 (en) 2008-04-02 2009-10-07 The Procter and Gamble Company Water-soluble pouch comprising a detergent composition
EP2280992A1 (en) 2008-05-16 2011-02-09 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
MX364987B (es) 2008-06-06 2019-05-17 Danisco Us Inc Alfa-amilasas variantes de bacillus subtilis y metodos de uso de las mismas.
CN102046783A (zh) 2008-06-06 2011-05-04 丹尼斯科美国公司 包含变体微生物蛋白酶的组合物和方法
ES2379951T3 (es) 2008-06-13 2012-05-07 The Procter & Gamble Company Bolsa multicompartimental
RU2560978C2 (ru) 2008-11-11 2015-08-20 ДАНИСКО ЮЭс ИНК. Протеазы, содержащие одну или несколько комбинируемых мутаций
US20100192985A1 (en) 2008-11-11 2010-08-05 Wolfgang Aehle Compositions and methods comprising serine protease variants
EP2857515B1 (en) 2008-11-20 2018-02-21 Novozymes Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
US20100125046A1 (en) 2008-11-20 2010-05-20 Denome Frank William Cleaning products
EP2213717B1 (en) 2009-01-28 2017-06-28 The Procter & Gamble Company Laundry multi-compartment pouch composition
WO2010088447A1 (en) 2009-01-30 2010-08-05 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2010091221A1 (en) 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP2216393B1 (en) 2009-02-09 2024-04-24 The Procter & Gamble Company Detergent composition
EP2406373B1 (en) 2009-03-10 2014-05-28 Danisco US Inc. Bacillus megaterium strain dsm90-related alpha-amylases, and methods of use, thereof
EP2414515A2 (en) 2009-04-01 2012-02-08 Danisco US Inc. Cleaning system comprising an alpha-amylase and a protease
WO2010117511A1 (en) 2009-04-08 2010-10-14 Danisco Us Inc. Halomonas strain wdg195-related alpha-amylases, and methods of use, thereof
GB0906281D0 (en) 2009-04-09 2009-05-20 Reckitt Benckiser Nv Detergent compositions
MY158753A (en) 2009-05-19 2016-11-15 Procter & Gamble A method for printing water-soluble film
AR079338A1 (es) 2009-12-09 2012-01-18 Danisco Us Inc Variantes de proteasa de bacillus y acidos nucleicos que codifican dichas variantes
CN102933227A (zh) 2009-12-22 2013-02-13 诺维信公司 包含增强性多肽和淀粉降解酶的组合物及其用途
WO2011076897A1 (en) 2009-12-22 2011-06-30 Novozymes A/S Use of amylase variants at low temperature
WO2011080353A1 (en) 2010-01-04 2011-07-07 Novozymes A/S Stabilization of alpha-amylases towards calcium depletion and acidic ph
MX364609B (es) 2010-01-29 2019-05-02 Monosol Llc Pelicula soluble en agua mejorada que tiene una mezcla de polimeros de pvoh, y envases realizados a partir de la misma.
EP3404087A1 (en) 2010-02-10 2018-11-21 Novozymes A/S Alpha-amylase variants with high stability in presence of a chelating agent
US20110240510A1 (en) 2010-04-06 2011-10-06 Johan Maurice Theo De Poortere Optimized release of bleaching systems in laundry detergents
JP6448904B2 (ja) 2010-05-06 2019-01-09 ダニスコ・ユーエス・インク サブチリシン変異体を含む組成物及び方法
WO2011153516A2 (en) 2010-06-03 2011-12-08 Mascoma Corporation Yeast expressing saccharolytic enzymes for consolidated bioprocessing using starch and cellulose
EP2399979B2 (en) 2010-06-24 2021-12-29 The Procter & Gamble Company Soluble unit dose articles comprising a cationic polymer
WO2012027404A1 (en) 2010-08-23 2012-03-01 The Sun Products Corporation Unit dose detergent compositions and methods of production and use thereof
WO2012059336A1 (en) 2010-11-03 2012-05-10 Henkel Ag & Co. Kgaa Laundry article having cleaning properties
GB201101536D0 (en) 2011-01-31 2011-03-16 Reckitt Benckiser Nv Cleaning article
JP6105560B2 (ja) 2011-05-05 2017-03-29 ダニスコ・ユーエス・インク セリンプロテアーゼ変異体を含む組成物及び方法
EP4345161A3 (en) 2011-10-28 2024-06-12 Danisco Us Inc Variant maltohexaose-forming alpha-amylase variants
DK4026902T3 (da) 2012-06-08 2025-07-14 Danisco Us Inc Variante alfa-amylaser med øget aktivitet på stivelsespolymerer
US20160160199A1 (en) * 2013-10-03 2016-06-09 Danisco Us Inc. Alpha-amylases from exiguobacterium, and methods of use, thereof
MX2016006489A (es) 2013-11-20 2016-08-03 Danisco Us Inc Alfa-amilasas variantes que tienen susceptibilidad reducida a la escision por proteasas y metodos de uso.
JP6474992B2 (ja) 2014-10-21 2019-02-27 浜松ホトニクス株式会社 光検出ユニット
US11920170B2 (en) * 2015-12-09 2024-03-05 Danisco Us Inc. Alpha-amylase combinatorial variants

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014164834A1 (en) * 2013-03-11 2014-10-09 Danisco Us Inc. Alpha-amylase combinatorial variants
WO2014164800A1 (en) * 2013-03-11 2014-10-09 Danisco Us Inc. Alpha-amylase combinatorial variants
WO2014164777A1 (en) * 2013-03-11 2014-10-09 Danisco Us Inc. Alpha-amylase combinatorial variants

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022041064A (ja) * 2020-08-31 2022-03-11 花王株式会社 α－アミラーゼ変異体
JP7510309B2 (ja) 2020-08-31 2024-07-03 花王株式会社 α－アミラーゼ変異体
JP2023095355A (ja) * 2021-12-24 2023-07-06 花王株式会社 アミラーゼ配合洗浄剤組成物

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